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"Sediaan tabir surya merupakan sediaan yang banyak digunakan untuk melindungi kulit dari radiasi sinar UV. Umumnya, pada formulasi tabir surya hanya digunakan zat aktif dengan satu mekanisme kerja. Kombinasi dua mekanisme kerja yaitu UV absorbent dan UV blocker dapat meningkatkan nilai efektif (SPF) dari sediaan tabir surya. Pada penelitian ini dilakukan formulasi krim tabir surya dengan mengkombinasikan zat aktif yang memiliki dua mekanisme kerja yaitu Butil metoksidibenzoilmetan dan Oktil metoksisinamat sebagai UV absorbent serta titanium dioksida sebagai UV blocker untuk diamati peningkatan nilai SPF dari krim tabir surya. Titanium dioksida diformulasikan dalam krim tabir surya yang masing-masing konsentrasinya 0%, 3%, 5%, dan 7%. Konsenstrasi UV absorbent yaitu Butil metoksidibenzoilmetan dan Oktil metoksisinamat berturutturut 2% dan 5%. Stabilitas fisik dari krim diamati, dan ditentukan nilai SPF dari keempat krim tersebut. Uji kestabilan fisik dilakukan dengan penyimpanan sediaan pada tiga suhu yang berbeda yaitu 4°C, 27°C, dan suhu 40°C. Selain itu juga dilakukan test mekanik dan cycling test. Penentuan nilai SPF dilakukan secara in vitro dengan pemaparan pada sinar matahari kemudian dilakukan pengukuran menggunakan spektrofotometer UV-Vis. Hasil uji stabilitas fisik dari keempat krim menunjukkan bahwa krim tersebut memiliki kestabilan fisik yang baik, tetapi adanya penambahan asam sitrat dapat menurunkan kestabilan krim tersebut. Nilai SPF dari krim tabir surya pada konsentrasi 0%, 3%, 5%, dan 7% berturut-turut adalah 4,94 ; 8,00 ; 8,84 dan 9,22. Peningkatan nilai SPF dari krim tabir surya ini dengan konsentrasi titanium dioksida 3%, 5%, dan 7% berturutturut adalah 62%, 79% dan 86%. Penambahan titanium dioksida mempengaruhi peningkatan nilai SPF.

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Sunscreen is one of cosmetic formulation which has been widely used to protect skin from UV radiation. Usually, sunscreen formulations only contains active substance with one mechanism of action. Combination of two mechanisms, UV absorbent and UV blockers, can increase the effectiveness value (SPF) of sunscreen formulation. In this research, sunscreen is formulated by combining two active substances that have different mechanism of action i.e Butyl methoxydibenzoylmethane and Octyl methoxycinnamate as the UV absorbent and titanium dioxide as the UV blocker in order to observe the increase SPF value of sunscreen. Titanium dioxide is formulated in sunscreen cream with the concentrations are 0%, 3%, 5%, and 7%. The concentration of the UV absorbent Butyl methoxydibenzoylmethane and Octyl methoxycinnamate consecutive 2% and 5%. Those four creams are observed for their physical stability and the SPF value. Physical stability test was conducted through three different temperatures storage, i.e. 4°C, 27-30°C, and 40°C. In addition, mechanical test and cycling test are also conducted. SPF value was determined by in vitro with exposing the four creams to the sunlight, which is then measured by spectrophotometer UV-Vis. Physical stability test showed that the cream has a good physical stability, however additional of citric acid can decrease the stability of the cream. SPF value of sunscreen cream at a concentration of 0%, 3%, 5%, and 7%, respectively, 4.94; 8.00; 8.84 and 9.22. Increment of the SPF value from sunscreen cream with titanium dioxide concentration of 3%, 5%, and 7% respectively 62%, 79% and 86%. The value of SPF is positively impacted by an increase of titanium dioxide concentration."

"[ABSTRAK Puskesmas merupakan unit pelaksana teknis dinas kesehatankabupaten/kota yang bertanggung jawab menyelenggarakan pembangunankesehatan di suatu wilayah kerja. Peran apoteker di Puskesmas adalah mengelolaperbekalan farmasi dan pelayanan farmasi klinik. Praktek Kerja Profesi Apotekerdi Puskesmas Kecamatan Sawah Besar bertujuan agar calon apoteker dapatmemahami peranan, tugas, dan tanggung jawab apoteker dalam praktek pelayanankefarmasian, memiliki pengetahuan, keterampilan, sikap perilaku serta wawasandan pengalaman nyata untuk melakukan praktek profesi dan pekerjaankefarmasian di Puskesmas, melihat dan mempelajari strategi dan pengembanganpraktek profesi Apoteker di Puskesmas, memiliki gambaran nyata tentangpermasalahan praktek dan pekerjaan kefarmasian di Puskesmas, berkomunikasidan berinteraksi dengan tenaga kesehatan lain yang bertugas di Puskesmas.Kegiatan yang dilakukan yaitu melakukan pelayanan farmasi klinik, megikutiPuskesmas Keliling, serta berdiskusi tentang pengelolaan perbekalan farmasi dantugas khusus. Puskesmas Kecamatan Sawah Besar perlu menambah sumber dayamanusia yakni apoteker sehingga pekerjaan kefarmasian dapat dilakukan secaramaksimal.ABSTRACT Puskesmas is unit of implementation public health office in regency which

has responsibility to organize health development in a working area. Pharmacist at

Puskesmas has role to manage pharmaceutical supply and clinical pharmacy

service. The purposes of Internship Program in Puskesmas Kecamatan Sawah

Besar are for understanding about the roles, jobs, and responsibilities of

pharmacist candidate in pharmaceutical practice, having knowledge, skills,

attitudes, perception, and real experiences in Puskesmas pharmaceutical practices,

finding strategic ways to develop the role of Puskesmas pharmaceutical and

having a real illustration about problems in pharmaceutical practices,

communicating and interacting with another Puskesmas health workers. The

activities were doing clinical pharmacy services, Puskesmas Keliling, and

discussed about management of pharmacy and special task. Puskesmas

Kecamatan Sawah Besar need to add human resources like pharmacist so that

pharmaceutical practice can be done well., Puskesmas is unit of implementation public health office in regency which

has responsibility to organize health development in a working area. Pharmacist at

Puskesmas has role to manage pharmaceutical supply and clinical pharmacy

service. The purposes of Internship Program in Puskesmas Kecamatan Sawah

Besar are for understanding about the roles, jobs, and responsibilities of

pharmacist candidate in pharmaceutical practice, having knowledge, skills,

attitudes, perception, and real experiences in Puskesmas pharmaceutical practices,

finding strategic ways to develop the role of Puskesmas pharmaceutical and

having a real illustration about problems in pharmaceutical practices,

communicating and interacting with another Puskesmas health workers. The

activities were doing clinical pharmacy services, Puskesmas Keliling, and

discussed about management of pharmacy and special task. Puskesmas

Kecamatan Sawah Besar need to add human resources like pharmacist so that

pharmaceutical practice can be done well.]"