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"ABSTRAKLatar belakang:Bayi laringomalasia primer memiliki komorbiditas yang tinggi akibat silent aspiration. Hingga saat ini, belum diketahui prevalensi disfagia dan data mengenai gambaran fungsi menelan bayi laringomalasia primer. Tujuan penelitian: Mengetahuiprevalensi disfagia dan gambaran fungsi menelanpada bayi laringomalasia primersertamengetahui kesesuaian antara SEES dan FEES.Metode: Penelitiancross-sectional yang bersifat deskriptifdan analitik komparatif terhadap 34subjek bayi laringomalasia primersecara konsekutif di RS Dr. Cipto Mangunkusumoperiode Januari-Maret 2020. Hasil:Prevalensi disfagiapada bayi laringomalasiaprimersebanyak 9 dari 34 subjek (26,5%). Gejala disfagia pada bayi< 6 bulan tersering adalah regurgitasi dan apneasaat menyusu (5/6), sedangkan pada bayi>6 bulan adalah terdengar banyak lendir di tenggorok (3/3). Komorbid terbanyak adalah kelainan genetikdan PRGE(3/9). Komplikasi terseringadalah pneumonia aspirasi (6/9). Pada pemeriksaan awal FEES, kontrol postural terganggu(7/9) merupakantanda yang paling sering ditemukan. Pada pemeriksaan FEES, preswallowing leakagedidapatkan pada konsistensi puree, tim saring, dan tim kasar. Pada pemeriksaan SEES dan FEES, residu, penetrasi,dan aspirasipalingbanyak didapatkan pada konsistensi susu. Silent aspirationdidapatkan pada4 dari 9subjek dengan disfagia. Pemeriksaan SEES memiliki kesesuaian dengan FEES berdasarkanuji McNemarpadaparameter ada tidaknya penetrasi, residu, dan aspirasi.Kesimpulan:Prevalensi disfagia pada bayi laringomalasia primersebanyak 9 dari 34 subjek(26,5%), penetrasi dan aspirasi didapatkan pada konsistensi air dan susuterutama pada bayi< 6 bulan, dan SEES memiliki kesesuaian dengan FEESdalam menilai fungsi menelanberdasarkan parameter ada tidaknya residu, penetrasi, dan aspirasi.

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Background:Silent aspiration is oftenunrecognized comorbidity in infants with congenital laryngomalacia with serious medical consequence. However, prevalence of dysphagia and characteristic of dysphagia ininfants with congenital laryngomalacia is still unknown. Aim: To find the prevalence and the overview of swallow function in infants with congenital laryngomalacia and also to know the conformity between SEES and FEES in assessing swallow function. Methods:This is a descriptive cross-sectional and comparative analytic study involving 34 infants with congenital laryngomalacia who came consecutivelytoDr. Cipto Mangunkusumo Hospitalon January-March 2019. Results: The prevalence of dysphagia was 9 out of 34 subjects (26,5%).Dysphagia symptom in infants<6 months was regurgitation and apneawhile bottle/breast feeding (5/6). Meanwhile, in infants>6 monthswaswet sounding voice (3/3). The comorbidities found mostly were geneticanomaly and GERD(3/9). The complication mostly was aspiration pneumonia (6/9). In pre-FESS examination, poor postural controlwas dominant(7/9). In FEES examination, preswallowingleakagewas found in puree, soft steam porridge, and rough steam porridge. In FEES and SEES examination, residue, penetration, and aspirationwas mostly found inthick liquid. Silent aspiration was found in 4 out of 9subjects with dysphagia. SEES has a conformity to FEES based on McNemar test in the presence of residue, penetration, and aspiration. Conclusion: The prevalence of dysphagia in infants with congenital laryngomalaciawas9 out of 34 subjects(26,5%). In FEES examination, penetration,and aspiration were found mostly in thin liquid, <6months of age predominantly.SEES has a conformity to FEES based on presence of residue, penetration, and aspiration in assessing swallow function."

"ABSTRAKLatar belakang: Laringomalasia merupakan kondisi kelemahan struktursupraglotis saat inspirasi sehingga menyebabkan sumbatan jalan nafas atas danmenimbulkan gejala stridor inspirasi. Stridor semakin memburuk pada posisiterlentang. Penyakit penyerta laringomalasia umumnya adalah reflukslaringofaring (RLF) yaitu 25-68%. RLF adalah pergerakan isi lambung secararetrograd menuju laring-faring, menimbulkan gejala dan tanda klinis yangbervariasi. Pemberian omeperazol dapat memperbaiki gejala regurgitasi danstridor serta memperpendek durasi perjalanan alamiah laringomalasiaTujuan: Mengetahui efektifitas omeperazol pada bayi dan anak denganlaringomalasia, mengetahui prevalensi RLF pada laringomalasia, ada tidaknyaRLF berdasar nilai reflux finding score (RFS) menurut Belafsky dan mengetahuiberat ringan gejala laringomalasia berdasar nilai laryngomalacia symptom score(LSS).Metode: Uji controlled trials pada 65 subyek laringomalasia, dibagi kedalamkelompok 42 subyek yang mendapat omeperazol 2 x 2 mg/kg/bb dan 23 subyekyang mendapat plasebo selama 3 bulanHasil : Kelompok omeperazol dengan gejala berat 58,8% mengalami perbaikandibanding kelompok plasebo 66,7% dengan nilai p = 0,716. Kelompokomeperazol dengan RLF positif 58,3% mengalami perbaikan dibandingkelompok plasebo 75% dengan nilai p = 1.0Simpulan : Prevalensi RLF positif sebesar 24,6% dan gejala berat sebesar 44,6%.Efektifitas pemberian omeperazol selama 3 bulan belum terbukti efektif dibandingplasebo berdasarkan perbaikan nilai LSS, RFS dan status gizi. Namun hasiltersebut hanya berlaku sebagai kesimpulan penelitian pendahuluan karena tidakoptimalnya besar sampel dan randomisasi subyek. Perlu penelitian lanjutan untukmembuktikan efektifitas omeperazol pada perbaikan skor LSS, skor RFS danstatus gizi bayi dan anak dengan laringomalasia

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ABSTRACTBackground: laryngomalacia is condition of floopy supraglottis stucture inrespiratory that trigger obstruction the upper airway and it causes symptom stridorinspiratory. Stridor can get worse in face up position. In general, the comorbidityof laryngomalacia is laryngopharyngeal reflux (LPR) about 25-68%. LPR is themovement of gaster retrogradely toward laryngopharyngeal and it triggers varioussymptom and clinical sign. The giving of omeperazole can improve the symptomof regurgitation and stridor and shorten the duration of natural disease oflaryngomalaciaObjective: Knowing the effectivity of giving omeperazole to the babies andchildren with laryngomalacia, knowing the prevalance of LPR to thelaryngomalacia, knowing the positibility of LPR based on the value of refluxfinding score (RFS) according to Belafsky and knowing severity of symptomlaryngomalacia based on the value of laryngomalacia symptom score (LSS).Method: Test on controlled trials on 65 samples with laryngomalacia and isdivided into 42 groups that have been given omeperazole 2x2 mg/kg/bw and 23samples that have been given placebo for 3 monthResult: Omeperazol groups with severe symptom showed the improvement of58,8% compared to placebo groups 66,7% with p = 0.716. Omeperazole groupswith RLF positive showed the improvement of 58,3% compared to placebogroups 75 % with p = 1.0Conclusion: The Prevalence of positive LPR based on RFS is 24,6% and withsevere symptom is 44,6%. The effectivity of giving omeperazole for 3 month hasnot proved effective compared to placebo based on the improvement of valueLSS, RFS and nutrition status. However such result is only valid for theconclusion of initial research because the size of samples were not either optimalor randomized. It is necessary to conduct research continution to prove theeffectivity of giving omeperazole on the improvement of LSS score, RFS scoreand nutrition status of babies and children with laryngomalacia"