Ditemukan 9 dokumen yang sesuai dengan query
Sheilla Nadia Valina
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BAKTI bekerja sama dengan PT. XYZ sebagai penyedia kapasitas dalam Proyek USO (Universal Service Obligation) menggunakan teknologi High Throughput Satellite dan memiliki 12 (dua belas) spot-beam Ku-band untuk mencakup semua wilayah Indonesia. PT. XYZ memiliki total kapasitas 1.314 MHz dalam arah forward dan 625.2 MHz dalam arah return untuk 12 (dua belas) spot-beam. Pada Proyek USO Penyediaan Kapasitas Satelit, ada dua jenis layanan yang disediakan, yaitu layanan ground segment Akses Internet dan Backhaul BTS dengan ...
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Depok: Fakultas Teknik Universitas Indonesia, 2020
T-Pdf
UI - Tesis Membership Universitas Indonesia Library
Marwan Fikri Arsyad
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Penyakit kardiovaskular adalah salah satu penyebab kematian yang banyak di dunia saat ini. Salah satu penyebab penyakit kardiovaskular adalah trombosis arterial yang bisa disebabkan oleh agregrasi platelet yang menutup arteri. Salah satu faktor penting dalam agregrasi platelet adalah aktivasi platelet oleh ADP dengan reseptor P2Y 12. Penelitian ini dilakukan untuk mencari kandidat inhibitor ADP P2Y 12 yang berasal dari tanaman herbal Indonesia menggunakan AutoDock dan AutoDock Vina. 96 senyawa yang terbukti memiliki aktivitas inhibisi terhadap ...
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Depok: Fakultas Farmasi Universitas Indonesia, 2017
S69153
UI - Skripsi Membership Universitas Indonesia Library
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Born out of a project of the IUPAC's committee on Medicinal Chemistry and Drug Development, this reference addresses past and current strategies for successful drug analog development, extending the previously published volume by nine new analog classes and eight case studies. Like its precursor, this volume also contains a general section discussing universally applicable strategies for analog discovery and development. Spanning a wide range of therapeutic fields and chemical classes, the two volumes together constitute ...
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Weinheim: Wiley-Vch, 2010
e20375683
eBooks Universitas Indonesia Library
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New strategies and techniques for today's fast-paced discovery process. Today, the pressure is on for high-throughput approaches to accelerate the generation, identification, and optimization of molecules with desirable drug properties. As traditional methods of analysis become antiquated, new analytical strategies and techniques are necessary to meet sample throughput requirements and manpower constraints. Among them, mass spectrometry has grown to be a front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometry provides ...
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Hoboken, New Jersey: John Wiley & Sons, 2005
e20394201
eBooks Universitas Indonesia Library
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This resource provides an integrated and comprehensive overview of modern approaches to drug lead discovery. Each chapter in this book reviews the theoretical background and application of a key technology in drug discovery, complemented by relevant case studies. The coverage includes the key approaches for drug design and discovery, high-throughput screening, fragment screening, multi-target drugs, de novo design, ADMET, natural products. This cutting-edge reference helps medicinal chemists in biotech, pharmaceutical, and other research contexts consider ...
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Hoboken, New Jersey: John Wiley & Sons, 2010
e20394228
eBooks Universitas Indonesia Library
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The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds. Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them. The book includes a table of the most successful drug analogs as based on ...
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Weinheim: Wiley-VCH, 2006
e20395920
eBooks Universitas Indonesia Library
Sotriffer, Christoph.
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Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable degree of accuracy. Alternatively, if active ligands are already available, molecular similarity searches can be used to find new molecules. This virtual screening can even ...
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Weinheim: Wiley-VCH, 2011
e20395196
eBooks Universitas Indonesia Library
Boca Raton: CRC Press, Taylor & Francis Group, 2008
615.19 HIG
Buku Teks Universitas Indonesia Library
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Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. The authors discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results ...
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Weinheim: Wiley-VCH, 2006
e20395921
eBooks Universitas Indonesia Library