Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :
ABSTRAK
Latar belakang: Menurut data tahun 2015 dari WHO dan UNAIDS, ada sekitar 36,7 juta orang di dunia hidup dengan HIV/AIDS. Di Indonesia, berdasarkan data dari Kementerian Kesehatan Republik Indonesia, prevalensi HIV mencapai 0,4 dimana terdapat 232.323 penderita HIV dan 86.780 penderita AIDS yang dilaporkan pada tahun 2016. Kualitas hidup terkait kesehatan pada pasien HIV dapat digunakan sebagai salah satu indikator keberhasilan terapi. Penelitian ini bertujuan untuk mengetahui kesahihan dan keandalan kuesioner WHOQOL-HIV BREF dalam bahasa Indonesia sebagai alat untuk mengukur kualitas hidup pada pasien HIV/AIDS. Metode: Penelitian potong lintang ini dilakukan di Poliklinik khusus HIV RSCM pada bulan November 2016 dengan cara consecutive sampling. Penelitian dilakukan dalam 2 tahap yaitu tahap awal yang merupakan proses adaptasi bahasa dan budaya dan tahap akhir yaitu uji kesahihan dan keandalan dari kuesioner. Hasil : Dari 56 responden yang mengisi kuesioner diketahui bahwa 69,6% laki-laki. Melalui pendekatan multi-trait scaling analysis didapatkan nilai koefisien korelasi yang tinggi terhadap skor total domainnya sehingga dapat dapat dikatakan memiliki validasi yang baik. Korelasi antar domain kuesioner WHOQOL-HIV BREF dan domain kuesioner SF-36 didapatkan 6 domain yang signifikan bermakna (p <0,005) dengan nilai koefisien korelasi kuat (r=0,60-0,79). Keandalan kuesioner dinilai dengan intra class correlation coefficient masing-masing domain 0,401-0,484 dan nilai Alpha Cronbach 0,513-0,798. Kesimpulan: Kuesioner WHOQOL-HIV BREF dalam bahasa Indonesia sahih dan andal. Diharapkan kualitas hidup dapat dipertimbangkan sebagai salah satu acuan respon pengobatan.

---

ABSTRACT
Background According to data from WHO and UNAIDS in 2015, approximately 36.7 million people worldwide living with HIV AIDS. In Indonesia, according to the data from the Ministry of Health Republik Indonesia, the HIV prevalence reached 0.4 where 232.323 people living with HIV and 86.780 people already in AIDS stage at 2016. Health status, which contributes to the quality of life in HIV patients, can be used as one indicators of the success of therapy. This study aims to determine the validity and reliability of the questionnaire WHOQOL HIV BREF in Indonesian as a tool for measuring the quality of life of HIV patients. Methods: A cross sectional study was conducted in HIV Integrated Service Unit Cipto Mangunkusumo General Hospital RSCM in November 2016 with consecutive sampling method. The study was conducted in two phases first, the language and cultural adaptation process and second phase was to test the validity and reliability of the questionnaire. Result: Total 56 respondents who filled the questionnaire, 69.6 % of them were men. Through a multi-trait scaling analysis, correlation coefficient value has a high correlation to the total score domain, and thus can be concluded that it has a good validation. Correlation between questionnaire domain WHOQOL-HIV BREF and SF-36 questionnaire domain obtained 6 significant domain (p <0.005) with a strong correlation coefficient (r=0.60 to 0.79). Reliability of the questionnaire was assessed by intra class correlation coefficient, each domain from 0.401 to 0.484 and 0.513 to 0.798 for Cronbach Alpha. Conclusion: The questionnaire WHOQOL-HIV BREF in the Indonesian language is valid and reliable. As such the quality of life can be considered as one criteria of a successful response of HIV treatment.

Abstrak :
Infeksi HIV menghasilkan radikal bebas yang merusak sel dan berbagai organ tubuh. Antioksidan berperan penting untuk mengatasi kerusakan akibat radikal bebas. Penelitian dengan desain potong lintang ini merupakan bagian dari penelitian bersama untuk mengetahui korelasi kadar antioksidan (beta karoten, vitamin C, E dan seng) dengan kadar SOD pada penderita HIV/AIDS di Pokdisus AIDS FKUI/RSUPNCM, Jakarta. Pengumpulan data dilakukan sejak akhir bulan Februari 2013 sampai Maret 2013 dengan metode consecutive sampling, didapatkan 52 orang subyek memenuhi kriteria penelitian. Hasil penelitian menunjukkan median usia subyek 33 (24-40) tahun dengan 51,9% laki-laki. Sebanyak 94,2% subyek mendapatkan terapi anti retrovirus. Nilai median jumlah limfosit T CD4+ adalah 245 (50-861) sel/µL dan 63,5% subyek berada pada kelompok CDC II. Status gizi 84,6% subyek normal dan lebih dengan nilai median 21,4 (14,4-32,4) kg/m2. Nilai rerata asupan energi subyek 1850,8±454,6 kkal/hari, 76,9% subyek memiliki asupan energi kurang dari kebutuhan total harian. Nilai Median asupan lemak subyek 51,4 (22-129,4) gram/hari dan 63,5% subyek memiliki asupan lemak kurang dari energi total. Semua subyek memiliki asupan serat yang kurang dari angka kecukupan serat, nilai rerata asupan serat subyek adalah 8,6±3,6 gram. Nilai rerata asupan beta karoten subyek 10,92±4,37 mg/hari, 88,5% memiliki asupan beta karoten cukup. Nilai median kadar beta karoten subyek 0,21 (0,01-0,72) µmol/L dan 76,9% subyek memiliki kadar beta karoten rendah. Rerata kadar SOD subyek sebesar 1542,1±281 U/gHb dan 53,8% subyek memiliki kadar SOD normal. Tidak didapatkan korelasi bermakna antara kadar beta karoten dengan SOD pada penderita HIV/AIDS (r=-0,174, p=0,217). ......Free radicals formed on the course of HIV infection can cause cellular and multiple organ damage. Antioxidants play an important role to minimize damage caused by these free radicals. This research is done using cross sectional design and is part of a joint study to assess the correlation between antioxidants (beta-carotene, vitamin C, E, and zinc) and SOD levels in HIV/AIDS patients at Pokdisus AIDS FKUI/RSUPNCM, Jakarta. The study is done from late February 2013 to March 2013 using consecutive sampling method, 52 subjects matched the study’s criteria. Study shows the age median value is 33 (24-40) years old, with 51.9% male. As much as 94.2% subjects were receiving anti retroviral therapy. Median value of CD4+ T lymphocyte count is 245 (50-861) cell/µL, 63.5% subjects belong in the CDC II category. Nutritional status for 84.6% subjects was normal and overweight with median value of 21.4 (14.4-32.4) kg/m2. Mean score for energy intake is 1850.8±454.6 kcal/day and as much as 76.9% subjects have energy intake less than total daily requirement. Median value of fat intake is 51.4 (22-129.4) grams/day and 63.5% subjects have fat intake less than total energy. All subjects were found to have fiber intake less than individual fiber requirement with mean score of 8.6±3.6 grams. Subjects’ mean score for beta-carotene is 10.92±4.37 mg/day and 88.5% of the subjects have adequate beta-carotene intake. Median value of beta-carotene level is 0.21 (0.01-0.72) µmol/L and 76.9% subjects have low beta-carotene level. SOD level mean score is 1542.1±281 U/gHb, 53.8% subjects had normal SOD level. This study found no significant correlation between beta-carotene and SOD levels in HIV/AIDS patients (r=-0.174, p=0.217).

Abstrak :
Abstrak
Men who have sex with men (MSM) comprise a population at risk for HIV infection. Assessing the Quality of Life (QOL) in MSM might be different than other populations. This study showed a secondary analysis from our previous research. It was needed to understand whether peer support and family acceptance had an impact on QOL of MSM living with HIV and ART (Antiretroviral Therapy). A total of 175 respondents were involved in this cross-sectional study that was carried out with purposive sampling. The questionnaires were translated to Bahasa and tested for validity and reliability. Data questionnaires completed were analyzed. Results showed that peer support was positively correlated with QOL (p= 0.023; OR= 2.070), and also, family acceptance was significantly related to QOL (p= 0.001; OR= 2.766). Thus, peer support and family acceptance are important factors affecting the well-being and QOL of MSM living with HIV and ART. This finding can be used for the improvement of QOL in people living with HIV.

Abstrak :
ABSTRAK
Saat ini proporsi kejadian terinfeksi HIV pada perempuan semakin meningkat. Kualitas hidup pada ibu rumah tangga dengan HIV rendah, hal ini dapat disebabkan oleh banyak faktor seperti HIV disclosure, stigma dan stres. Tujuan : Mengidentifikasi hubungan HIV disclosure, stigma dan stres terhadap kualitas hidup ibu rumah tangga dengan HIV di Kupang, menggunakan desain penelitian cross sectional. Sampel terdiri dari 120 ibu rumah tangga dengan HIV di poli VCT Sobat yang dipilih dengan teknik consecutive sampling. Hasil : Ada hubungan antara stres (p=0,011;α=0,005) dan stigma (p=0,001;α=0,005) dengan kualitas hidup ibu rumah tangga dengan HIV. Faktor paling dominan yang mempengaruhi kualitas hidup ibu rumah tangga dengan HIV adalah tingkat stres sedang (p=0,009;α=0,005; OR=7,667; 95% CI= 1,678-35,032). Kesimpulan : Stres dan stigma berhubungan dengan kualitas hidup ibu rumah tangga denfan HIV di Kupang. Direkomendasikan untuk dilakukan deteksi dini tingkat stres pada ibu rumah tangga dengan HIV agar dapat dilakukan intervensi awal untuk mengurangi stigma dan meningkatkan kualitas hidup.

---

ABSTRACT
The proportion of HIV-infected women currently increases. Quality of life in housewives with HIV is low, this can be caused by many factors such as HIV disclosure, stigma and stress. Objective: To identify the relationship between HIV disclosure, stigma and stress on the quality of life of housewives with HIV in Kupang, using a cross sectional study design. The sample consisted of 120 housewives with HIV in poly VCT friends who were selected by consecutive sampling technique. Results: There was a relationship between stress (p = 0.011; α = 0.005) and stigma (p = 0.001; α = 0.005) with the quality of life of housewives with HIV. The most dominant factor affecting the quality of life of housewives with HIV is the moderate stress level (p = 0.009; α = 0.005; OR = 7.667; 95% CI = 1.678-35.032). Conclusion: Stress and stigma are associated with quality of life of housewives with HIV in Kupang. Early detection of stress levels in housewives with HIV is recommended so that early intervention can be carried out to reduce stigma and improve quality of life.