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Abstrak :
ABSTRAK
Kondisi stres memiliki efek yang buruk terhadap respon imun, sehingga rentan akan infeksi, termasuk penyakit periodontal. Salah satu biomarker yang dapat mengindikasikan penyakit periodontal adalah interleukin-6 (IL-6). Tiga puluh delapan mahasiswa program profesi FKG UI. Subjek diinstruksikan untuk mengusi kuisioner Dental Environment Stress (DES) dan dilakukan pemeriksaan periodontal dan pengambilan sampel cairan krevikular gingiva serta dianalisis untuk mengetahui kadar IL-6 dengan teknik ELISA. Walaupun uji statistik menunjukkan hubungan yang lemah antara tingkatan stres dengan kondisi periodontal dan kadar IL-6, kondisi klinis menunjukkan kecenderungan perburukan kondisi periodontal seiring peningkatan skor stres.

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ABSTRACT
Stress conditions have a bad effect on the immune response, leading to an imbalance between the host and the parasite so susceptible to infections, including periodontal disease. One biomarker that can indicate periodontal disease is interleukin-6 (IL-6). Thirty eight samples were instructed to filled the Dental Environment Stress (DES) questionnaire, periodontal examination and gingival crevicular fluid were collected. Although statistical tests showed a weak relationship between stress levels and the periodontal condition levels of IL-6, showed a trend of worsening clinical condition of periodontal conditions with increases in stress scores.

Abstrak :
ABSTRAK Stres faktor risiko penyakit periodontal, yang meningkatkan kadar interleukin-1β yang berperan pada kerusakan jaringan periodontal. Tujuan : analisis hubungan antara stres akademik terhadap kondisi jaringan periodontal dan kadar interleukin-1β dalam cairan krevikular gingiva. Metode : 38 orang subjek mengisi kuasioner GDES, pemeriksaan klinis, pemeriksaan laboratorium kadar interleukin-1β dengan ELISA. Hasil : Terdapat perbedaan bermakna antara tingkatan stres akademik dengan kondisi jaringan periodontal dan kadar interleukin-1β (p<0,05); tidak terdapat perbedaan bermakna antara kadar interleukin-1β dengan kondisi jaringan periodontal (p>0,05). Kesimpulan : Stres faktor risiko penyakit periodontal dengan peningkatan kadar interleukin-1β

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ABSTRACT Background: Stress is a risk factor for periodontal disease, with increase levels of interleukin-1β that act for periodontal destruction. Objective: To analyze the relationship between academic stress in dental specialist programme in Dentistry on periodontal tissue conditions and levels of interleukin-1β in gingival fluid krevikular. Methods: 38 subjects fill the quasioner GDES, periodontal examination and laboratorium examination of interleukin-1β with the ELISA test. Results: Significant differences between academic stress to periodontal tissue and levels of interleukin-1β (p<0,05); no significant differences between levels of interleukin-1β to periodontal tissues (p>0,05). Conclusion: Stress is periodontal risk factor with elevated levels of interleukin-1β