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ABSTRAKLatar belakang: Distribusi histologis kanker paru berbeda antara laki-laki dan perempuan. Perempuan perokok lebih sering terkena adenokarsinoma sedangkan laki-laki perokok lebih sering terkena karsinoma sel skuamosa. Insidens kanker paru perempuan di Asia Timur dinyatakan 2-3 kali lebih banyak dibandingkan perempuan negara barat dan sekitar 70% bukan perokok. Tujuan: Mengetahui angka tahan hidup pasien kanker paru pada perempuan, karakteristik dan faktor-faktor yang mempengaruhi ketahanan hidupnya. Metode: Penelitian dilakukan dengan metode cohort retrospektif dari rekam medis pasien kanker paru yang dirawat dan meninggal di RS Persahabatan dalam kurun waktu Januari 2008-Desember 2012. Hasil: Subjek dalam penelitian ini diperoleh 83 orang dengan rata-rata usia 53 tahun, pendidikan SLTA 49,4%, 86,7% bukan perokok, 71,1% belum pernah pengobatan tuberkulosis, keluhan utama terbanyak nyeri dada 28,9%, dan 57,8% tampilan pasien baik (PS≤2). Karakteristik tumor 81,9% adenokarsinoma, 100% stage IV, 71,1% metastasis di pleura dan masalah pasien terbanyak efusi pleura ganas 42,2%. Lima puluh tiga persen pasien tidak mendapatkan terapi tumor. Masa tengah tahan hidup pasien kanker paru perempuan 42 hari, dan angka tahan hidup (ATH) 1 bulan 59%, 6 bulan 18,1%, 1 tahun 6%, 2 tahun 1,2%. Faktor yang dianggap mempengaruhi ketahanan hidup pasien kanker paru perempuan adalah tampilan pasien dan pemberian terapi. Kesimpulan: Angka tahan hidup pasien kanker perempuan di RS Persahabatan lebih rendah daripada penelitian lain, hal ini dikarenakan semua subjek merupakan stage IV dan sebagian tampilannya buruk. Faktor tampilan yang bagus dan pemberian terapi dianggap meningkatkan ketahanan hidup pasien kanker paru perempuan.
ABSTRACTIntroduction:Histological distribution of lung cancer is different between man and woman. Women smokers are more often exposed to adenocarsinoma, but men smokers are more often get squamous cell carsinoma. Incidence of lung cancer in East Asian women expressed 2-3 times more than the western countries and about 70% are non-smokers. Objective: To know the survival rate of lung cancer in women, the characteristics factors that’s influence the survival. Method: The study was conducted using a retrospective cohort of medical records of patients treated for lung cancer and died at RSUP Persahabatan during the period January 2008-December 2012. Results: Subjects in this study were obtained 83 men with an average age of 53 years, 49.4% high school education, 86.7% non-smokers, 71.1% had never been the treatment of tuberculosis, most major complaint of chest pain 28.9%, and 57 , 8% of patients look good (PS ≤ 2). Tumor characteristics adenocarcinoma 81.9%, 100% stage IV, 71.1% and pleural metastasis in most patients the problem 42.2% of malignant pleural effusions. Fifty-three percent of patients did not receive tumor therapy. Median survival of lung cancer in women 42 days, and the survival rate (SR) of 1 month 59%, 6 months 18.1%, 1-year 6%, 2 years 1.2%. Factors considered to affect the survival of lung cancer in this study are performance status and therapy. Conclusion: Therapy in patients with lung cancer can improve survival of lung cancer in women even though had advanced stage, especially if it has a good performance status."
