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Abstrak :
Latar Belakang : Penggunaan terapi hormon memiliki efek samping pada payudara yang dapat terdeteksi pada ultrasonografi (USG) berupa peningkatan ketebalan jaringan fibroglandular yang berhubungan dengan peningkatan risiko kanker payudara. Hingga saat ini masih terdapat kontroversi mengenai efek samping terapi hormon tibolone terhadap payudara. Tujuan Penelitian : Mengetahui perubahan ketebalan jaringan fibroglandular payudara setelah terapi hormon tibolone. Metode : Penelitian ini berlangsung dari bulan Desember 2013 hingga Agustus 2015 di Departemen Radiologi RSUPN dr. Cipto Mangunkusumo dengan desain penelitian berupa studi kuasi eksperimental dengan amandemen berupa pengambilan data USG payudara sebelum dan sesudah terapi hormone tibolon. Pengukuran dengan USG payudara dilakukan di empat regio (superior, inferior, medial dan lateral) yang kemudian dilakukan analisis terhadap rerata perubahan ketebalan jaringan fibroglandular sebelum dan sesudah terapi hormon tibolone. Hasil : Dari 40 subjek yang dianalisis, terdapat 36 subjek yang mengalami peningkatan ketebalan jaringan fibroglandular. Terdapat perbedaan bermakna (p<0,001) pada ketebalan jaringan fibroglandular payudara sebelum dan sesudah 3 bulan pemberian tibolon. Indeks massa tubuh (p = 0,020) dan riwayat kontrasepsi hormonal (p=0,015) merupakan faktor yang memengaruhi peningkatan ketebalan jaringan fibroglandular payudara sesudah terapi hormon tibolon. Sedangkan paritas, usia melahirkan anak pertama, riwayat menyusui, usia menarke, usia menopause dan riwayat kontrasepsi hormonal tidak berhubungan. Kesimpulan : Terdapat peningkatan ketebalan jaringan fibroglandular berdasarkan pemeriksaan USG payudara perempuan menopause yang mendapat terapi hormon tibolone. ......Background : The use of hormone therapy has side effects in the breast which detected on ultrasound by increasing the thickness of breast fibroglandular tissue associated with increased risk of breast cancer. Until now there is still controversy regarding the side effects of tibolone on the breast tissue. Purpose : This study aims to determine the thickness changes of the fibroglandular tissue due to tibolone hormone therapy. Methods : This research was done between December 2013 untill August 2015 in Department of Radiology, dr. Cipto Mangunkusumo Hospital. Design of this research is a quasi-experimental study with the amendment in the form of data retrieval breast ultrasound before and after tibolon hormone therapy. Measurements with breast ultrasound was done in four regions (superior, inferior, medial and lateral) then the average change in fibroglandular thickness was analyzed. Results : Of the 40 subjects were analyzed, there were 36 subjects showed significant increase (p <0.001) of breast fibroglandular tissue thickness after 3 months of tibolone hormone therapy. The body mass index (p = 0.02) and a history of hormonal contraception (p = 0,01) were factors that influence the increase of fibroglandular thickness post tibolone hormone therapy. While parity, age of first child, history of breastfeeding, age of menarche, age of menopause and history of hormonal contraception were not related. Conclusions : There is an increase of fibroglandular tissue thickness by breast ultrasound examination of menopausal woman who received tibolone hormone theraphy.

Abstrak :
This book is the one of the few textbooks that summarizes the latest information dated to inflammatory breast cancer. The uniqueness of this book is that it has summarized the latest molecular and mechanistic findings, which may lead to novel diagnostic tool or therapeutic approach to fight this deadly disease.

Abstrak :
Encompassing the entire spectrum of breast imaging and diagnostics, this acclaimed text provides a systematic and pragmatic guide for all clinicians involved in diagnosing breast disease. The new third edition has been fully updated to include advances in mammography, ultrasound, breast MRI, percutaneous interventions, and emerging technologies, with pros and cons and evidence-based approaches throughout. Special features of the third edition: Coverage of the field, with comprehensive sections on examination procedures and technical requirements; histologic, clinical, and radiologic appearance of a wide range of breast pathologies; results of international screening studies; and much more. Nearly 1,200 clear radiographic images showing normal findings, benign and malignant disorders, and post-traumatic, post-surgical, and post-therapeutic changes to the breast. Innovations in digital mammography, tomosynthesis, and computer assisted detection (CAD); new chapters on imaging of implants, lesions of uncertain malignant potential, developing technologies; and more. A systematic, highly reproducible methodology for detection, diagnosis, and assessment of findings. Easy-to-follow flowcharts for the diagnostic work-up of both typical and atypical cases. Written by world-renowned authorities with decades of clinical experience, this book provides a brilliant orientation to the multimodality diagnostic approach and therapeutic significance of breast imaging findings. It is an essential reference and board review for radiologists, residents and fellows, gynecologists, oncologists, surgeons, technologists, and any other interdisciplinary specialist working to improve outcomes in breast disease

Abstrak :
Frozen section library : breast provides an easy reference and pocket book about the nuances of adequately handling breast specimens in a fashion that meets the increasingly complex environment of breast pathology. The pros and cons of frozen section versus use of touch imprint as well as related quality assurance requirements are addressed. Other less common uses of intraoperative evaluation, such as diagnosis and margin evaluation are described. The volume includes recommended guidelines for evaluation and documentation of specific gross pathologic features, in conjunction with radiological imaging. Techniques and protocols for such examinations are illustrated. The volume closes with an overview of the newly published guidelines for handling a variety of breast specimens, which are intended to be used for assessment of predictive factors.