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"Kenaikan suhu global bumi hingga 2 0C memberi pengaruh nyata terhadap produktivitas sapi. Efek negatif kenaikan suhu global dapat dikurangi dengan mempelajari adaptasi hewan pada tingkat individu hingga gen. penelitian bertujuan untuk mempelajari respons fisiologi dan ekspresi gen termoregulator Hsp90 dan ATP1A1 sapi Bali di beberapa daerah di Inonesia. Pengumpulan data fisiologi, sampel darah sapi dn kondisi lingkungan dilakukan di Cipelang Kabupaten Bogor, Desa Lompo Tengah Kabupaten Barru, Desa Sumber Klampok Kabupaten Buleleng, dan Desa Telaga Bertong Kabupaten Sumbawa Barat. Sampel darah diambil dari vena jugularis untuk diisolasi RNA, lalu ditranskripsi balik menjadi cDNA yang kemudian dilanjutkan dengan proses qRT-PCR. Ekspresi gen dilakukan dengan metode komparasi deltas Ct dengn normalisasi oleh gen GADPH.Analisis data fisiologi dan kondisi lingkungan dengan uji multivariate dan korelasi Pearson, sedangkan analisis ekspresi gen dengan uji Kruskal-Wallis. Suhu udara, kelembaban udara dan intensitas matahari di empat lokasi berbeda nyata p=0 , tetapi kecepatan angin tidak berbeda nyata p=0,056 , sehingga mempengaruhi perbedaan suhu kulit, suhu rektum, suhu tubuh dan laju pernapasan. Respons sapi terhadap cekaman panas dengan cara peningkatan suhu kulit, suhu rektum, suhu tubuh, laju pernapasan, peningkatan ekspresi gen Hsp90 dan ATP1A1. Rasio ekspresi gen Hsp90/GADPH dan ATP1A1/GADPH berbeda setiap lokasi penelitian karena dipengaruhi kondisi iklimnya.

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Earth 39 s global temperature rise to 2 0C had a significant effect on the productivity of cattle. The negative effect of the global temperature rise can be reduced by studying the adaptation of animals at the individual level to the gene level. The research aimed to study the physiology response and gene expression of Hsp90 dan ATP1A1 on Bali cattle in some areas in Indonesia. The physiology profiles of cattle, blood samples and environmental conditions were collected from Cipelang, Lompo Tengah village, Sumber Klampok village and Telaga rtong village. Blood samples were taken from jugular vein to isolate RNA that was reverse transcribed info cDNA followed by qRT PCR process. Gene expression was performed by the comparative delta Cycle threshold Ct method which GADPH as internal control gene.

Analysis of physiological data and environmental conditions were done by multivariate test and Pearson correlation test, whereas gene expression analized by Kruskal Wallis test. Air temperature, air humidity and the light intensity at four locations were significantly different p 0, but the wind speed did not differ significantly p 0,056, thus affecting differences in skin, rectal and body temperature, and respiratory rae. Bali cattle responded to heat stress by increasing the skin, rectal and body temperatures respiratory rate, and upregulated of Hsp90 and ATP1A1 genes. The ratio of the genes expression of Hsp90 GADPH an ATP1A1 GADPH were difference each the study sites because it 39 s climatic conditions."

"ABSTRAKKetidakseimbangan termoregulasi berisiko terjadi pada Bayi Berat Lahir Rendah secarastruktur tubuh masih belum matang. Tujuan penulisan karya ilmiah akhir ini adalahmemberikan gambaran tentang bagaimana penerapan model konservasi Levine dalamproses asuhan keperawatan pada bayi berat lahir rendah untuk mencegahketidakseimbangan termoregulasi, juga memberikan gambaran langkah pencegahannyaselama transport BBLR intra hospital. Pada lima kasus kelolaan, masalah termoregulasiyang terjadi meliputi inefektif termoregulasi, risiko inefektif termoregulasi, hipotermiadan hipertermia. Pendekatan teori Konservasi Levine menggunakan prinsip konservasienergi, konservasi integritas struktural, konservasi integritas personal dan konservasiintegritas sosial dilakukan sebagai intervensi keperawatan dalam mengatasi masalahtermoregulasi. Evaluasi yang didapatkan, masalah ketidakseimbangan termoregulasidapat teratasi selama perawatan. Selanjutnya langkah pencegahan ketidakseimbangantermoregulasi pada BBLR yang baru lahir selama transportasi intra hospital dilakukandengan penyusunan Standar Prosedur Operasional Transportasi BBLR Intra hospitaldengan Kangaroo Care berdasarkan model konservasi Levine.

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Thermoregulatory imbalances are at risk for Low Birth Weight Infants, the bodystructure is still immature. The purpose of writing this final scientific paper is toprovide an overview of how the application of the Levine conservation model in thenursing care process in low birth weight infants to prevent thermoregulatoryimbalance, as well as provide an overview of its preventive measures during intrahospital LBW transport. In five cases of management, thermoregulation problemsthat occurred include ineffective thermoregulation, thermoregulatory ineffectiverisks, hypothermia and hyperthermia. The Levine Conservation theory approachuses the principles of energy conservation, conservation of structural integrity,conservation of personal integrity and conservation of social integrity carried out asnursing interventions in overcoming the problem of thermoregulation. Evaluationobtained, the problem of thermoregulation imbalance can be resolved duringtreatment. The next step is to prevent thermoregulation imbalance in newborn LBWduring intra-hospital transportation by preparing Standard Operating Proceduresfor LBW Intra-hospital Transportation with Kangaroo Care based on the Levineconservation model."

"Bayi prematur mempunyai banyak risiko gangguan kesehatan yang dapat dialami akibat fungsi dan sistem tubuh yang belum sempurna. Mandi merupakan tindakan non invasif yang dilakukan setiap hari dan dapat mengakibatkan stres pada bayi. Respon stres yang ditunjukkan oleh bayi prematur selama prosedur memandikan dapat berupa menangis, tremor, kehilangan suhu tubuh, dan perubahan tanda-tanda vital. Tujuan penelitian ini adalah memberikan gambaran penerapan Model Konservasi Levine pada asuhan keperawatan bayi prematur dengan risiko gangguan termoregulasi melalui teknik memandikan swaddled bath. Penelitian ini menggunakan metode studi kasus terhadap lima bayi prematur yang berisiko mengalami gangguan termoregulasi melalui pendekatan proses keperawatan. Gangguan termoregulasi dapat menghambat proses adaptasi bayi prematur dalam mencapai keutuhannya, sehingga diperlakukan intervensi berbasis Model Konservasi Levine melalui empat prinsip konservasi. Hasil penelitian menunjukkan bahwa Model Konservasi Levine dapat digunakan dalam asuhan keperawatan bayi prematur dengan masalah termoregulasi melalui penggunaan teknik memandikan swaddled bath.

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Premature babies have many risks of health problems that can be experienced due to immature body functions and systems. Bathing is a non-invasive action that is performed every day and can cause stress to the baby. The stress respone shown by premature babies during the bathing procedure can be in the form of crying, tremors, loss of body temperature, and changes in vital signs. The purpose of this study was to provide an overview of the application of the Levine Conservation Model in nursing care of premature infants with a risk of thermoregulation disorders through the swaddled bath technique. This research used a case study method of five premature babies who were at risk of experiencing thermoregulation disorders through the nursing process approach. Disorders of thermoregulation can hinder the adaptation process of premature babies in achieving their wholeness, so interventions based on the Levine Conservation Model are treated through four principles of conservation. The results of this study indicate that the Levine Conservation Model can be used in nursing care of premature infants with thermoregulation problems through the use of the swaddled bath technique."

"Pengontrolan suhu tubuh sangat penting pada bayi prematur karena fluktuasi suhu meningkatkan ketidakseimbangan tingkat metabolisme bayi baru lahir. Pengaturan suhu tubuh yang buruk menjadi sasaran faktor lingkungan yang dapat menyebabkan kehilangan panas yang cepat sehingga rentan terhadap peningkatan risiko morbiditas dan mortalitas akibat hipotermia. Tujuan dari penelitian ini untuk mengetahui penerapan teori Konservasi  Levine dalam mengatasi masalah risiko termoregulasi tidak efektif pada bayi baru prematur di ruang Perinatologi. Model Konservasi Levine berfokus pada peningkatan adaptasi dan mempertahankan integritas diri (wholeness) dengan menggunakan prinsip konservasi. Masalah risiko termoregulasi tidak efektif merupakan salah satu gambaran terganggunya konservasi energi mencakup ketersediaan dan pengeluaran energi bayi baru lahir dan menyebabkan terjadinya peningkatan konsumsi oksigen dengan mempertahankan fungsi normal termogenesis

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Body temperature control is very important in preterm infant because temperature fluctuations improve the balance. Poor body temperature regulation is the target of environmental factors that can cause rapid heat loss, making them susceptible to an increased risk of morbidity and mortality due to hypothermia. The purpose of this study was to determine the application of Levine's Conservation theory in overcoming the problem of ineffective thermoregulation risk in premature newborns in the Perinatology room. Levine's Conservation Model focuses on increasing adaptation and maintaining wholeness using conservation principles. The problem of the risk  ineffective thermoregulation is one of the features of the disruption energy conservation and energy expenditure of baby and causes an increase in oxygen consumption by maintaining normal thermogenesis function.

 

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"This book summarises the newest information on seasonal adaptation in animals. Topics include animal hibernation, daily torpor, thermoregulation, heat production, metabolic depression, biochemical adaptations, neurophysiology and energy balance. The contributors to this book present interdisciplinary research at multiple levels ranging from the molecular to the ecophysiological, as well as evolutionary approaches. The chapters of this book provide original data not published elsewhere, which makes it the most up-to-date, comprehensive source of information on these fields. The book’s subchapters correspond to presentations given at the 14th International Hibernation Symposium in August 2012 in Austria. "