Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :
Reaksi anafilaksis adalah reaksi hipersensitivitas serius yang mengancam nyawa jika tidak ditangani dengan cepat. Data epidemiologi mengenai reaksi anafilaksis di Indonesia masih sangat kurang yang ditandai dengan belum adanya laporan yang secara spesifik meneliti prevalens dan insidens kasus anafilaksis di Indonesia. Diagnosis dan penanganan yang tepat dan cepat oleh tenaga medis penting untuk menangani pasien dengan kasus anafilaksis, termasuk pasien anak. Berdasarkan beberapa penelitian yang dilakukan negara lain, pengetahuan dokter, termasuk dokter spesialis anak mengenai reaksi anafilaksis masih kurang baik. Penelitian cross-sectional ini dilakukan untuk mengetahui tingkat pengetahuan dokter spesialis anak yang tergabung dalam Ikatan Dokter Spesialis Anak cabang Jakarta mengenai reaksi anafilaksis dan faktor-faktor yang memengaruhinya. Pengetahuan mengenai reaksi anafilaksis serta faktor yang memengaruhinya didapatkan dari responden dengan pengisian kuesioner secara tertulis. Pada akhir penelitian, sampel yang didapat berjumlah 104 orang. Penelitian ini menunjukkan bahwa 52,9% memiliki pengetahuan cukup, 26,9% memiliki pengetahuan kurang, dan 20,2% memiliki pengetahuan baik mengenai reaksi anafilaksis. Pada analisis antara tingkat pengetahuan dan faktor yang memengaruhinya, hasil uji Chi-Square dan/atau Jonckheere-Terpstra menunjukkan bahwa tidak ada hubungan antara lama praktek sebagai dokter spesialis anak, jumlah kasus anafilaksis yang pernah ditangani, serta jumlah sumber pengetahuan mengenai reaksi anafilaksis terhadap tingkat pengetahuan responden (p>0,05). Sebagai kesimpulan, pengetahuan sebagian dokter spesialis anak mengenai reaksi anafilaksis cukup dan faktor-faktor yang diuji tidak berhubungan terhadap tingkat pengetahuan responden. ...... Anaphylaxis is a severe hypersensitivity reaction that can be fatal if not treated properly. Epidemiological data and research on anaphylaxis in Indonesia are generally scarce. Due to its fast onset and possible fatal outcomes, proper diagnosis and treatment of patients with anaphylaxis, including pediatric patients, by physicians are very important. Based on several studies conducted in other countries, a considerable proportion of physicians, including pediatricians, still have low level of knowledge on the diagnosis and treatment of anaphylaxis. This cross-sectional study aims to understand the level of knowledge about anaphylaxis among pediatricians of the Jakarta branch of Indonesian Pediatric Society. Level of knowledge on anaphylaxis and several possible related factors were measured/obtained with a questionare. By the end of the study, 104 valid questionares were analized. This study found that 52,9% of respondents have moderate level of knowledge, 26,9% have low level of knowledge, and 20,2% have high level of knowledge on anaphylaxis.  Chi-Square and/or Jonckheere-Terpstra analysis on the correlation between level of knowledge and its possible influencing factors indicated that there is no correlation between years of practice as a pediatrician, number of anaphylaxis cases treated, and source of study materials to the pediatricians’ level of knowledge of anaphylaxis (p>0,05). In conclusion, the level of knowledge among pediatricians of the Jakarta branch of Indonesian Pediatric Society is mostly moderate, with no related factors found.

Abstrak :
Purpose: Differences in definitions of condition, relevant triggers, and the geographical locations of study centers, cause estimates of the prevalence of anaphylaxis to vary. Recent epidemiological data indicate that the incidence of anaphylaxis is rising. Methoda: to investigate the causes and clinical features of anaphylaxis in Korean adults, factors associated the severity of the condition, and serious outcomes, a retrospective medical record review performed on adult patients diagnosed with anaphylaxis between 2007 and 2011 in 15 university Hospital of South Korea. Results: A total of 1.806 cases (52% age 16-86 years) were reported. Cutaneous symptoms (84.0%), combined with respiratory (53, 9%) and/or cardiovascular (55.4%) symptoms, were the most frequent presentations. Using a recognized grading system, 1.776 cases could be classified as either mild, 340; moderate, 690; or severe, 746. Although eliciting factors varied significantly by age, gender, and regional and seasonal factors, drugs (46.5%; including nonsterodial ) anti-inflammatory drugs, antibiotics, and radiocontrast media) were the most common cause of anaphylaxis, followed by foods(24.2%), insect stings (16,4%), exercise (5,9%), and unknown etiology (7.0%). All age, multi-organ involvement, a history of allergic disease, and drug-induced anaphylaxis, were significant predictors of serious outcomes requiring hospital admission or prolongation of hospital stay. Epinephrine auto-injectors were prescribed for 74% of reported cases. Conclusions: The principal causes of Anaphilaxis in Korean adults were drugs, food, and insect stings. Drug-associated anaphylaxis, a history of allergic disease, multi organ involvement, older aged, were identified as predictors of serious outcomes.