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Raya Henri Batubara
"ABSTRAK
Latar belakang: Kolesistektomi merupakan tindakan abdomen tersering dan saat ini
kolesistektomi laparoskopi (KL) merupakan baku emas dan telah dilakukan pada 90% kasus
kolesistitis simtomatik. Tujuan penelitian ini adalah untuk mengetahui hasil KL di RSCM,
Jakarta.
Metode: Penelitian retrospektif observasional ini menggunakan data dari departemen bedah
divisi digestif RSCM dari bulan Januari hingga Desember 2014. Partisipan penelitian ini
adalah pria atau wanita yang berusia 23-66 tahun yang menjalani KL. Tindakan bedah
dilakukan baik berupa perawatan 1 hari (one day care (ODC)) maupun elektif. Data yang
dikaji adalah temuan preoperatif dan intraoperatif, durasi operasi, lama rawat inap, dan angka
konversi ke tindakan kolesistektomi terbuka (open). Kemudian kami menganalisis faktor
yang mempengaruhi angka konversi.
Hasil: Jumlah pasien yang masuk inklusi adalah 90 orang. Usia rata-rata 43,9 tahun (SE=1,26
tahun) dengan jumlah pasien wanita 61 orang (67,8%). Median durasi operasi adalah 90±36,9
menit dimana pasien yang konversi membutuhkan operasi lebih dari 2 jam lebih banyak
(12% vs 1,5%), namun tidak bermakna secara statistik (p= 0,63). Median lama rawat inap
adalah 9±27.2 hari dan meningkat bermakna pada kasus yag konversi (24±9 hari, p = 0.011).
Median lama pre-operasi = 7±26,8 hari, dan pasca-operasi = 2±3.8 hari, dengan 13,3% pasien
dilakukan endoscopic retrograde cholangio-pancreatography (ERCP) sebelum KL. Cedera
duktus biliaris komunis (CBDK) ditemukan pada 3 kasus (3,33%). Konversi menjadi
laparotomi dibutuhkan pada 4,44% kasus. Faktor yang mempengaruhi angka konversi hanya
pada kasus adhesi (RR (95%IK) = 25,7 (2,4-273,5); p=0,007.
Kesimpulan temuan: kolesistektomi laparoskopi menawarkan lama rawat inap yang lebih
singkat. Durasi operasi pendek dan prosedur ini standard, aman, dan efektif di institusi kami. ABSTRACT
Background: Cholecystectomy is the most frequently performed abdominal operation and
currently laparoscopic cholecystectomy (LC) is considered gold standard being performed in
90% cases of symptomatic gallstones. The aim of the study was to determine results obtained
with LC at our hospital, RSCM, Jakarta.
Methods: This retrospective observational study was conducted in digestive divison in
surgery department of RSCM using data from January to December 2014. The study
participants were patients of both gender aged 23?66 years undergoing LC. Surgery was
performed either in one day care (ODC) or elective schedule. Demographic variables,
preoperative and intraoperative findings, mean operation time, hospital stay, and conversion
rate were evaluated. Factors influencing rate of conversion were also studied.
Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) with
a female 61 (67.8%). Median operative time was 90±36.9 minutes which converted cases
patient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant
(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in converted
cases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation
= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography
(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).
Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate of
conversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007.
Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time is
short and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation and
currently laparoscopic cholecystectomy (LC) is considered gold standard being performed in
90% cases of symptomatic gallstones. The aim of the study was to determine results obtained
with LC at our hospital, RSCM, Jakarta.
Methods: This retrospective observational study was conducted in digestive divison in
surgery department of RSCM using data from January to December 2014. The study
participants were patients of both gender aged 23?66 years undergoing LC. Surgery was
performed either in one day care (ODC) or elective schedule. Demographic variables,
preoperative and intraoperative findings, mean operation time, hospital stay, and conversion
rate were evaluated. Factors influencing rate of conversion were also studied.
Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) with
a female 61 (67.8%). Median operative time was 90±36.9 minutes which converted cases
patient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant
(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in converted
cases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation
= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography
(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).
Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate of
conversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007.
Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time is
short and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation and
currently laparoscopic cholecystectomy (LC) is considered gold standard being performed in
90% cases of symptomatic gallstones. The aim of the study was to determine results obtained
with LC at our hospital, RSCM, Jakarta.
Methods: This retrospective observational study was conducted in digestive divison in
surgery department of RSCM using data from January to December 2014. The study
participants were patients of both gender aged 23?66 years undergoing LC. Surgery was
performed either in one day care (ODC) or elective schedule. Demographic variables,
preoperative and intraoperative findings, mean operation time, hospital stay, and conversion
rate were evaluated. Factors influencing rate of conversion were also studied.
Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) with
a female 61 (67.8%). Median operative time was 90±36.9 minutes which converted cases
patient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant
(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in converted
cases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation
= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography
(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).
Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate of
conversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007.
Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time is
short and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation and
currently laparoscopic cholecystectomy (LC) is considered gold standard being performed in
90% cases of symptomatic gallstones. The aim of the study was to determine results obtained
with LC at our hospital, RSCM, Jakarta.
Methods: This retrospective observational study was conducted in digestive divison in
surgery department of RSCM using data from January to December 2014. The study
participants were patients of both gender aged 23?66 years undergoing LC. Surgery was
performed either in one day care (ODC) or elective schedule. Demographic variables,
preoperative and intraoperative findings, mean operation time, hospital stay, and conversion
rate were evaluated. Factors influencing rate of conversion were also studied.
Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) with
a female 61 (67.8%). Median operative time was 90±36.9 minutes which converted cases
patient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant
(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in converted
cases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation
= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography
(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).
Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate of
conversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007.
Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time is
short and procedure is standard, safe and effective in our institution.;Background: Cholecystectomy is the most frequently performed abdominal operation and
currently laparoscopic cholecystectomy (LC) is considered gold standard being performed in
90% cases of symptomatic gallstones. The aim of the study was to determine results obtained
with LC at our hospital, RSCM, Jakarta.
Methods: This retrospective observational study was conducted in digestive divison in
surgery department of RSCM using data from January to December 2014. The study
participants were patients of both gender aged 23?66 years undergoing LC. Surgery was
performed either in one day care (ODC) or elective schedule. Demographic variables,
preoperative and intraoperative findings, mean operation time, hospital stay, and conversion
rate were evaluated. Factors influencing rate of conversion were also studied.
Results: A total of 90 patients were included. Mean age was 43.9 years (SE=1.26 years) with
a female 61 (67.8%). Median operative time was 90±36.9 minutes which converted cases
patient needed to operate in more than 2 hours (12% vs 1.5%), but not statistically significant
(p= 0.63). Median hospital stay was 9±27.2 days that significantly increased in converted
cases (24±9 days, p-value= 0.011). Median of pre-operation = 7±26.8 days, and postoperation
= 2±3.8 days, with 13.3% patients underwent endoscopic retrograde cholangiopancreatography
(ERCP). Common bile duct injury (CBDI) was found in 3 cases (3.33%).
Conversion to laparotomy was required in 4.44% cases. Factors that influenced the rate of
conversion included was only adhesion (RR (95%CI) = 25.7 (2.4-273.5), p=0.007.
Findings: Laparoscopic cholecystectomy offers shorter hospital stay. The operative time is
short and procedure is standard, safe and effective in our institution."
Fakultas Kedokteran Universitas Indonesia, 2015
SP-PDF
UI - Tugas Akhir  Universitas Indonesia Library
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Febiansyah Ibrahim
"Latar belakang. Adenokarsinoma kolorektal AKR merupakan keganasan gastrointestinal yang sering ditemukan dan mempengaruhi lebih dari satu juta individu di seluruh dunia. Identifikasi histologis invasi limfovaskular telah dikenali sebagai indikasi potensial untuk metastasis KGB dan indikasi prognostik dan prediktor dari luaran pasien.Metode.Penelitian ini adalah penelitian retrospektif dengan regresi logistik multivariat.Hasil. Hasil penelitian didapatkan faktor usia, diferensisasi tumor, pT, dan jenis kelamin tidak mempengaruhi kejadian invasi limfovaskular. AKR diferensiasi sedang dan jenis kelamin laki-laki didapatkan kejadian invasi limfovaskular yang lebih besar dibanding diferensiasi lain dan jenis kelamin perempuan.Kesimpulan. Faktor-faktor yang mepengaruhi invasi limfovaskular yaitu diferensiasi tumor, usia, jenis kelamin, lokasi tumor dan derajat patologis T tidak bermakna secara statistik. Invasi limfovaskular merupakan prediktor terjadinya metastasis KGB.

Background. Adenocarcinoma colon and rectum are the most common gastrointestinal malignancy and afflict more than one million individual worlds wide. Histologic finding of limphovascular invasion has known as potensial indication for lymphatic metastatic and prognostic indication and predictor of patient outcome.Methods. This studi was retrospective, logistic regression test was used for multivariate analysis.Result. Result of this study ara gender, age, tumor differentiation and pT not significantly related to lymphovascular invasion. Mild differentiation and male gender recorded had bigger risk to had lymphovascular invasion descriptively.Conclusion. Factors affecting lymphovascular invasion ie tumor differentiation, age, sex, tumor location and pathologic T degree were not statistically significant. Lymphovascular invasion is a predictor of limph nodes metastasis."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library