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"ABSTRAKObjektif: Pembedahan merupakan tatalaksana paliatif utama dari kanker periampular stadium lanjut, namun hal tersebut memiliki angka komplikasi postoperatif, rekurensi penyakit, dan mortalitas yang tinggi. Objektif dari penelitian ini yaitu untuk mengetahui faktor prognostik dan sintasan penyakit selama 1 tahun dari kanker periampular stadium lanjut pada Rumah Sakit Cipto Mangunkusumo. Metode: Penelitian ini merupakan uji analisis sintas dengan desain kohort retrospektif. Data dikumpulkan dari pendaftaran per bulan dari Divisi Bedah Digestif dan rekam medis dari Rumah Sakit Cipto Mangunkusumo dari Januari 2015 hingga Desember 2017. Sintasan penyakit satu tahun dianalisis dengan metode Kaplan-Meier. Dilakukan analisis bivariat dan multivariat dari masing-masing variabel pada sintasan satu tahun pasien. Hasil: Sintasan penyakit selama 1 tahun dari pasien post-double bypass yaitu 19% dengan median (minimal-maksimal) sintasan yaitu 159 (2-365) hari. Berdasarkan perbandingan antarkelompok sintasan pasien, hemoglobin (p=0,013) dan klasifikasi ASA (p=0,001) memiliki estimasi sintasan yang bermakna secara statistik. Pada analisis multivariat, jenis kelamin (p=0,250, HR=3,910) dan nilai laboratorium preoperatif (albumin (p=0,350, HR=0,400), aspartat aminotransferase (AST) (p=0,13, HR=5,110) dan alanin aminotransferase (ALT) (p=0,280, HR=0,05)) berhubungan dengan sintasan. Kesimpulan: Sintasan selama 1 tahun pada pasien post-double bypass pada Rumah Sakit Cipto Mangunkusumo rendah. Laju mortalitas satu bulan yang rendah mengindikasikan bahwa double bypass merupakan prosedur yang aman. Faktor prognostik yang berhubungan dengan sintasan yang rendah yaitu jenis kelamin perempuan dan nilai laboratorium preoperatif (albumin, AST, ALT).

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ABSTRACTObjective: Surgery is the main palliative treatment of advanced periampullary cancer, however it has high number of post-operative complication, disease recurrence and mortality. The objective of the current study was to examine prognostic factors and one year survival rate of advanced stage periampullary cancer in Cipto Mangunkusumo Hospital. Methods: This is a survival analysis test study with retrospective cohort design. Data were collected from monthly registration of Digestive Surgery Division and medical records from Cipto Mangunkusumo Hospital from January 2015 until December 2017. One year survival rate were analyzed with Kaplan-Meier method. Bivariate and multivariate analysis of each variable on one year survival of the patient were done. Result: One year survival rate of the post-double bypass patients is 19% with median (min-max) survival 159 (2-365) days. From the comparison of survival rate based patients grouping, hemoglobin (p=0.013) and ASA classification (p=0.001) have significant survival estimation statistically. In multivariate analysis, gender (p=0.250, HR=3.910) and preoperative laboratory values (albumin (p=0.350, HR=0.400), aspartate aminotransferase (AST) (p=0.13, HR=5.110) and alanine aminotransferase (ALT) (p=0.280, HR=0.05)) are associated with survival rate. Conclusion: One year survival rate of post double bypass patients in Cipto Mangunkusumo hospital is low. Low one month mortality rate indicates double bypass is a safe procedure. Prognostic factors that associated with lower survival are woman gender and preoperative laboratory value (albumin, AST, ALT)."

"[ABSTRAK Infeksi daerah operasi merupakan hal yang harus diperhatikan oleh para ahli bedah mengingat tingginya morbiditas dan mortalitas pada pasien yang menderita infeksi daerah operasi Penulis ingin melakukan analisa secara garis besar bagaimana infeksi daerah operasi terutama pada infeksi daerah operasi pada operasi dengan golongan operasi bersih dan bersih tercemar Dilakukan penelitian retrospektif terhadap semua pasien divisi bedah digestif FKUI RSCM dari september 2012 hingga Juli 2014 Pasien dinilai berdasarkan kondisi preoperatif intraoperatif dan pasca operatif Dari data yang terhimpun selama penelitian di dapatkan 57 pasien menderita infeksi daerah operasi Delapan persen dari seluruh total operasi bedah digestif Keganasan kolorektal adenocarcinoma kolorektal menempati urutan pertama 22 39 Didapatkan 2 kasus yang merupakan operasi dengan tipe operasi bersih Didapatkan 17 kasus yang merupakan operasi dengan tipe bersih terkontaminasi Kata kunci Infeksi Daerah Operasi Pembedahan abdominal ABSTRACTSurgical site infection SSI have been responsible for the increasing cost morbidity and mortality related to surgical operations and continue to be a major problem even in hospitals with most modern facilities This study aimed to determine the incidence of SSI in the abdominal surgeries Obsteric and Gynecology surgery was excluded It was conducted over a period of 12 months All Surgeries 791 cases where abdominal wall was opened were considered for the study Wound class was considered as clean clean contaminated contaminated and dirty The data collected includes details of timing of antimicrobial prophylaxis surgical wound infection types of surgeries emergency and elective nutrional status preoperative condition ASA preoperative bed stay intraoperative condition bleeding amount duration of operative and death rate The overall surgical wound infection rate was 8 Predominantly male had SSI than female Mostly case at productive age 25 65 years Colorectal was leading case of SSI 22 cases There was one case of clean surgery , Surgical site infection SSI have been responsible for the increasing cost morbidity and mortality related to surgical operations and continue to be a major problem even in hospitals with most modern facilities This study aimed to determine the incidence of SSI in the abdominal surgeries Obsteric and Gynecology surgery was excluded It was conducted over a period of 12 months All Surgeries 791 cases where abdominal wall was opened were considered for the study Wound class was considered as clean clean contaminated contaminated and dirty The data collected includes details of timing of antimicrobial prophylaxis surgical wound infection types of surgeries emergency and elective nutrional status preoperative condition ASA preoperative bed stay intraoperative condition bleeding amount duration of operative and death rate The overall surgical wound infection rate was 8 Predominantly male had SSI than female Mostly case at productive age 25 65 years Colorectal was leading case of SSI 22 cases There was one case of clean surgery ]"