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"Antibiotik sebagai terapi infeksi bakteri berperan sangat besar dalam meningkatkan hasil pengobatan pasien. Selain dampak positif, antibiotik juga dapat menimbulkan permasalahan baru yaitu resistensi antibiotik. Pemerintah Indonesia melakukan strategi pengendalian resistensi antimikroba dengan cara  penggunaan antibiotik secara bijak dan meningkatkan ketaatan terhadap prinsip pencegahan dan pengendalian infeksi. Evaluasi penggunaan antibiotik dapat dilakukan secara kuantitatif dan kualitatif. WHO merekomendasikan Anatomical Therapeutic Chemical (ATC) dan Defined Daily Dose (DDD) sebagai bentuk evaluasi penggunaan obat, khususnya antibiotik secara kuantitatif. Penelitian ini bertujuan untuk menganalisis penggunaan antibiotik periode Januari-Maret 2023 di RSUP Fatmawati dengan metode ATC/DDD dan segmen DU90%. Data diperoleh dari resep obat yang dikumpulkan oleh Instalasi Sistem Rumah Sakit (ISIRS) RSUP Fatmawati dan data lama rawat inap pasien didapatkan dari laporan Tata Usaha (TU) Farmasi RSUP Fatmawati. Data kemudian diolah untuk mendapatkan nilai DDD per 100 hari rawat dan DDD per 100 hari rawat tiap antibiotik yang diurutkan dari data terbesar hingga terkecil. Data kemudian dihitung % kumulatif dan diklasifikasikan antibiotik yang termasuk segmen 90%. Hasil penelitian diperoleh 28 antibiotik yang memiliki kode ATC dan DDD digunakan di RSUP Fatmawati periode Januari-Maret 2023.Nilai total DDD/ 100 hari rawat inap antibiotik di RSUP Fatmawati sebesar 63,112 dan  levofloxacin merupakan antibiotik dengan nilai DDD/ 100 hari rawat inap tertinggi yaitu  30,181. Antibiotik yang termasuk dalam segmen DU90% adalah levofloxacin, ampisilin-sulbaktam, ciprofloxacin, azithromisin, cefexime, cefoperazone, clindamisin, sulfomethoxazole dan trimethoprim.

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Antibiotics as a therapy for bacterial infections play a very large role in improving patient treatment outcomes. In addition to the positive impact, antibiotics can also cause new problems, namely antibiotic resistance. The Indonesian government has a strategy to control antimicrobial resistance by using antibiotics wisely and increasing adherence to the principles of infection prevention and control. Evaluation of antibiotic use can be done quantitatively and qualitatively. WHO recommends Anatomical Therapeutic Chemical (ATC) and Defined Daily Dose (DDD) as a form of quantitative evaluation of drug use, especially antibiotics. This study aims to analyze the use of antibiotics for the period January-March 2023 at Fatmawati General Hospital using the ATC/DDD method and the DU90% segment. Data obtained from prescription drugs collected by the Hospital System Installation (ISIRS) of Fatmawati General Hospital and data on the length of hospitalization of patients obtained from the report of Administration (TU) Pharmacy of Fatmawati General Hospital. The data were then processed to obtain the value of DDD per 100 days of care and DDD per 100 days of care for each antibiotic sorted from the largest to the smallest data. The data then calculated the cumulative % and classified antibiotics that included 90% segment. The results obtained 28 antibiotics that have ATC codes and DDD used in Fatmawati General Hospital for the period January-March 2023. The total value of DDD / 100 days of antibiotic hospitalization at Fatmawati General Hospital is 63,112 and levofloxacin is an antibiotic with the highest DDD / 100 days of hospitalization value of 30,181. Antibiotics included in the DU90% segment are levofloxacin, ampicillin-sulbactam, ciprofloxacin, azithromycin, cefexime, cefoperazone, clindamycin, sulfomethoxazole and trimethoprim."

"Obat digunakan manusia untuk memengaruhi sistem fisiologi atau kondisi patologi dalam rangka penetapan diagnosis, pencegahan, penyembuhan, pemulihan, peningkatan kesehatan dan kontrasepsi. Berdasarkan laporan Badan Narkotika Nasional (BNN), terjadi peningkatan pravelensi penyalahgunaan Narkotika, Psikotropika, dan Zat Aditif (NAPZA) dari 1,80% pada tahun 2019 menjadi 1,95% di tahun 2021. Salah satu langkah yang dilakukan Pemerintah Indonesia dalam penurunan kasus penyalahgunaan NAPZA adalah peredaran obat narkotika dan psikotropika dalam bentuk obat jadi diatur secara ketat oleh perundang-undangan. Apoteker sebagai penanggung jawab PBF bertanggung jawab terhadap aktivitas pengadaan, penerimaan, penyimpanan, penyaluran obat khususnya narkotika dan psikotropika. Penelitian ini bertujuan untuk menelaah implementasi Standar Prosedur Operasional (SPO) Pengadaan, Penerimaan, Penyimpanan, dan Penyaluran Narkotika dan Psikotropika di PT. Kimia Farma Trading & Distribution Jakarta 2. Data diperoleh dengan membaca SPO, Melakukan GAP analisis antara SPO pengadaan, penerimaan, penyimpanan, dan penyaluran Narkotika dan Psikotropika dengan CDOB, Observasi implemntasi SPO di KFTD Jakarta 2 dan Wawancara dengan personil yang terlibat dalam proses distribusi obat. Hasil penelitian didapatkan Standar Prosedur Operasional (SPO) Pengadaan, Penerimaan, Penyimpanan serta Penyaluran Nakotika dan Psikotropika di Kimia Farma Trading & Distribution (KFTD) Jakarta 2 telah memenuhi standar Cara Distribusi Obat yang Baik (CDOB) dan seluruh kegiatannya telah dilaksanakan sesuai dengan SPO yang berlaku.

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Drugs are used by humans to affect physiological systems or pathological conditions in order to establish diagnosis, prevention, healing, recovery, health improvement and contraception. Based on a report from the National Narcotics Agency, there was an increase in the prevalence of narcotics, psychotropic drugs and addictive substances abuse from 1.80% in 2019 to 1.95% in 2021. One of the steps taken by the Government of Indonesia in reducing cases of drug abuse is that the circulation of narcotic drugs and psychotropic drugs in the form of finished medicines is strictly regulated by legislation. Pharmacists as the person in charge of Drug Distributor are responsible for the activities of procurement, receipt, storage, and distribution of drugs, especially narcotics and psychotropic drugs. This study aims to examine the implementation of Standard Operating Procedures for Procurement, Receipt, Storage, and Distribution of Narcotics and Psychotropic Drugs at PT Kimia Farma Trading & Distribution Jakarta 2. Data were obtained by reading SOP, conducting GAP analysis between SOP procurement, receipt, storage, and distribution of Narcotics and Psychotropic drugs with Good Distribution Practice (GDP), observing SOP implementation at KFTD Jakarta 2 and interviewing personnel involved in the drug distribution process. The results of the study obtained that the Standard Operating Procedures (SOP) for Procurement, Receiving, Storage and Distribution of Narcotics and Psychotropic drugs at Kimia Farma Trading & Distribution (KFTD) Jakarta 2 have met the standards of the Good Distribution Practice (GDP) and all activities have been carried out in accordance with the applicable SPO."

"Salah satu penyakit kronis yang banyak ditemui di Indonesia adalah hiperkolesterolemia. Berdasarkan hasil Riset Kesehatan Dasar Nasional tahun 2013, sebanyak 35,9% penduduk Indonesia memiliki kadar kolesterol > 200 mg/dL. Kondisi tersebut dapat memicu aterosklerosis pada dinding pembuluh darah dan Penyakit Jantung Koroner (PJK). Kedua penyakit tersebut menjadi penyebab kematian utama di dunia yang mencapai 17,3 juta dari 54 juta total kematian per tahun. Apoteker sebagai penyedia layanan kefarmasian bertanggungjawab untuk memberikan pelayanan yang dapat meningkatkan kualitas hidup pasien. Salah satunya dengan memberikan pelayanan telefarmasi. Penelitian ini bertujuan untuk mengembangkan kuesioner untuk  konseling, Pemantauan Terapi Obat (PTO), dan Monitoring Efek Samping Obat (MESO) pada pasien hiperkolesterolemia di Apotek Roxy Hasyim Ashari secara telefarmasi. Data diperoleh dengan melakukan studi literatur menggunakan buku maupun publikasi ilmiah berbahasa Indonesia dan berbahasa Inggris. Hasil penelitian didapatkan Kuesioner Pengatahuan Pasien Hiperkolesterolemia yang mendapatkan Obat Simvastatin, Kuesioner Ketepatan Penggunaan Obat Simvastatin oleh Pasien Hiperkolesterolemia, Kuesioner Adherence to Refills and Medications Scale (ARMS), Statin Experience Assessment Questionnaire (SEAQ).

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One of the chronic diseases commonly found in Indonesia is hypercholesterolemia. Based on the results of the National Basic Health Research in 2013, 35.9% of the Indonesian population had cholesterol levels > 200 mg/dL. This condition can trigger atherosclerosis of the blood vessel walls and Coronary Heart Disease (CHD). Both diseases are the leading cause of death in the world, reaching 17.3 million out of 54 million total deaths per year. Pharmacists as pharmaceutical service providers are responsible for providing services that can improve the quality of life of patients. One of them is by providing telepharmacy services. This study aims to develop questionnaires for counseling, Monitoring Drug Therapy (PTO), and Monitoring Drug Side Effects (MESO) in hypercholesterolemia patients at Roxy Hasyim Ashari Pharmacy telepharmaceutically. Data were obtained by conducting literature studies using books and scientific publications in Indonesian and English. The results of the study obtained the Knowledge Questionnaire for Hypercholesterolemia Patients who get Simvastatin Drugs, the Appropriateness of Using Simvastatin Drugs by Hypercholesterolemia Patients Questionnaire, the Adherence to Refills and Medications Scale (ARMS) Questionnaire, Statin Experience Assessment Questionnaire (SEAQ)."

"Kanker menjadi salah satu penyebab kematian utama pada 10 juta kasus di seluruh dunia pada tahun 2020. Salah satu terapi yang dapat diberikan kepada pasien kanker yaitu menggunakan obat sitostatika. Proses produksi obat sitostatika menurut CPOB memerlukan penanganan khusus seperti produksi di gedung terpisah dari produk non sitostatika, area produksi yang dedikatif, pengaturan sistem tata udara, dan pengaturan kelas kebersihan untuk proses produksi sediaan steril, serta perlindungan terhadap personel dan produk. Penelitian ini bertujuan untuk menelaah proses produksi sediaan sitostatika di PT CKD OTTO Pharmaceuticals, menganalisis kesesuaian proses produksi sediaan sitostatika dengan CPOB dan menganalisis perbedaan proses produksi sediaan sitostatika dibandingkan proses produksi sediaan steril lainnya. Pengambilan data dilakukan dengan observasi, wawancara, dan studi literatur. Hasil penelitian menunjukkan proses produksi sediaan sitostatika di PT CKD OTTO Pharmaceuticals meliputi tahapan  penerimaan bahan awal dan bahan kemas, sampling bahan awal dan bahan kemas, penyiapan sebelum produksi, sterilisasi, pencucian vial dan depyrogenation, penimbangan material, mixing, transfer produk, filling, freeze drying, crimping, external washer, inspeksi visual, pelabelan, pengemasan sekunder, hingga proses agregasi. Seluruh proses produksi sediaan sitostatika di PT CKD OTTO Pharmaceuticals telah sesuai dengan CPOB meliputi aspek bangunan-fasilitas, personalia, kelas kebersihan yang digunakan, pengaturan tekanan udara, sistem terkait produksi, hingga monitoring lingkungan. Terakhir, perbedaan proses produksi sediaan sitostatika dibandingkan proses produksi sediaan steril lainnya terletak pada bangunan, tekanan udara yang digunakan, tahapan penerimaan bahan awal, penimbangan material, mixing, filing, dan external washer.

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Cancer is one of the leading causes of death in 10 million cases worldwide in 2020. One of the therapies that can be given to cancer patients is using cytostatic drugs. The production process of cytostatics according to CPOB requires special handling such as production in a separate building from non-cytostatics products, dedicative production areas, air system settings, and hygiene class settings for the production process of sterile preparations, as well as protection of personnel and products. This study aims to examine the production process of cytostatics preparations at PT CKD OTTO Pharmaceuticals, analyze the suitability of the production process of cytostatics preparations with CPOB and analyze the differences in the production process of cytostatics preparations compared to the production process of other sterile preparations. Data collection was carried out by observation, interview, and literature study. The results showed that the production process of cytostatics preparations at PT CKD OTTO Pharmaceuticals included the stages of receiving initial materials and packaging materials, sampling initial materials and packaging materials, pre-production preparation, sterilization, vial washing and depyrogenation, material weighing, mixing, product transfer, filling, freeze drying, crimping, external washer, visual inspection, labeling, secondary packaging, to the aggregation process. The entire production process of cytostatics preparations at PT CKD OTTO Pharmaceuticals is in accordance with CPOB, including aspects of building-facilities, personnel, hygiene classes used, air pressure settings, production-related systems, and environmental monitoring. Finally, the difference in the production process of cytostatics preparations compared to the production process of other sterile preparations lies in the building, the air pressure used, the stages of receiving initial materials, weighing materials, mixing, filing, and external washers."

"Suatu kondisi dimana jumlah sel darah merah atau konsentrasi hemoglobin lebih rendah dari biasanya. Berdasarkan penelitian sebelumnya, 32% remaja di Indonesia mengalami anemia. Anemia pada remaja secara signifikan mengganggu konsentrasi belajar yang berdampak pada prestasi siswa. Selain itu, 48,9% ibu hamil mengalami anemia. Ibu hamil yang mengalami anemia terjadi peningkatkan risiko kelahiran prematur, gangguan perkembangan mental pada anak yang lahir, hingga kematian neonatal. Puskesmas sebagai pelayanan kesehatan tingkat pertama dapat memberikan pelayanan berupa promotif, preventif, kuratif, dan rehabilitatif. Salah satu kegiatan promotif dan preventif yang dapat dilakukan di puskesmas adalah upaya penanggulangan anemia defiensi besi pada remaja, wanita usia subur, dan ibu hamil. Penelitian ini bertujuan mencegahan anemia pada remaja, wanita usia subur, dan ibu hamil melalui media Leaflet Tablet Tambah Darah (TTD). Penelitian dilakukan dengan melakukan studi literatur dengan kata kunci “anemia, zat besi, tablet tambah darah” melalui e-book, artikel penelitian, website WHO, website Kementerian Kesehatan Republik Indonesia, serta peratutan pemerintah. Data kemudian diolah secara deskriptif untuk disajikan menggunakan laporan.  Data dari laporan kemudian dipilih  untuk disajikan pada leaflet. Leaflet memuat informasi cseperti data konsumsi zat besi pada remaja, prevalensi anemia, cara pencegahan anemia, suplementasi TTD, aturan minum TTD, efek samping TTD serta mitos terkait TTD sebagai upaya promosi konsumsi dan kepatuhan minum TTD serta pencegahan anemia.

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Anemia is a condition where the number of red blood cells or hemoglobin concentration is lower than normal. Based on previous research, 32% of adolescents in Indonesia experience anemia. Anemia in adolescents significantly interferes with learning concentration which has an impact on student achievement. In addition, 48.9% of pregnant women experience anemia. Pregnant women who experience anemia have an increased risk of premature birth, mental development disorders in children born, and neonatal death. Public Health Center as a first-level health service can provide services in the form of promotive, preventive, curative, and rehabilitative. One of the promotive and preventive activities that can be carried out at Public Health Center is efforts to overcome iron deficiency anemia in adolescents, bride-to-be, and pregnant women. This study aims to prevent anemia in adolescents, bride-to-be, and pregnant women through the media of Blood Addition Tablet Leaflet. The research was conducted by conducting a literature study with the keywords “anemia, iron, blood supplement tablets” through e-books, research articles, the WHO website, the website of the Ministry of Health of the Republic of Indonesia, and government regulations. The data was then processed descriptively to be presented using reports.  Data from the report was then selected to be presented in the leaflet. The leaflet contains information such as data on iron consumption in adolescents, prevalence of anemia, how to prevent anemia, blood supplement tablets supplementation, blood supplement tablets supplementation drinking rules, side effects and related myths."