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"Orang lanjut usia (lansia) merupakan kelompok usia yang rentan terhadap dehidrasi. Dehidrasi pada lansia memiliki efek yang berbahaya, bahkan hingga menyebabkan kematian, namun dapat dicegah dengan memenuhi kebutuhan cairan harian. Pengetahuan, sikap, dan perilaku mengenai asupan cairan harian akan membantu mencegah kondisi dehidrasi, tetapi belum terdapat penelitian terkait pada lansia di Indonesia. Penelitian ini bertujuan untuk mengetahui pengetahuan, sikap, dan perilaku lansia mengenai asupan cairan harian dan hubungannya dengan faktor lain yaitu usia, jenis kelamin, tingkat pendidikan, serta jenis sumber infirmasi. Studi cross-sectional telah dilaksanakan di Pejaten Barat, Jakarta pada Januari hingga Februari 2012 dengan subyek sebanyak 100 orang yang diperoleh dari consecutive sampling. Semua subyek mengisi keseluruhan kuesioner mengenai data demografi, pengetahuan, sikap, dan perilaku mengenai asupan cairan harian. Hasil penelitian menunjukkan bahwa sebanyak 51% subyek berpengetahuan baik, 80% bersikap cukup, 72% berperilaku baik. Analisis bivariat pada setiap variabel menunjukkan adanya hubungan antara usia dengan perilaku (uji Kolmogorov-Smirnov: p=0,010), namun tidak terdapat hubungan pada variabel lainnya. Selain itu, tidak terdapat hubungan bermakna antara pengetahuan dengan sikap, pengetahuan dengan perilaku, dan sikap dengan perilaku mengenai asupan caran harian melalui uji Kolmogorov-Smirnov. Oleh sebab itu, intervensi untuk meningkatkan pengetahuan, sikap, dan perilaku harus dilakukan dengan metode yang berbeda.

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Elderly is an age group that have a big risk on dehydration. Dehydration in elderly have a negative effect, even dead, but it can be prevented by good hydration. Knowledge, attitude, and behavior concerning daily fluid intake will prevent dehydration, but there is limited study concerning that among elderly in Indonesia.

he aim of this study was to determine the knowledge, attitude, and behavior concerning daily fluid intake and related factor among elderly such as age, sex, education level, and the kind of information sources.

A cross-sectional study was conducted at Pejaten Barat, Jakarta on January to February 2012. Consecutive sampling technique was used to choose 100 subjects. All subjects completed questionnaires on demographic characteristics, knowledge, attitude, and practice.

The were 51% subjects had good knowledge, 80% subjects had quite good attitude, and 72% subjects had good behavior. We found that age was related to behavior (Kolmogorov-Smirnov test: p=0,010), but there was no relationship between another variabel. There are no relationship between knowledge and attitude, attitude and behavior, and also knowledge and behavior concerning daily fluid intake by Kolmogorov-Smirnov test. Therefore, intervention is needed to increase knowledge, attitude, and behavior with different method for each."

"Latar Belakang. Anak dengan gangguan neurodevelopmental memerlukan upaya terapi terpadu untuk meningkatkan kualitas hidupnya. Studi ini bertujuan mengetahui pengaruh implantasi eksosom, stimulasi auditori binaural beat, dan terapi konvensional terhadap lima domain BDI-2 pada anak dengan gangguan neurodevelopmental.Metode. Studi kohort retrospektif dengan rekam medis di RSUPN dr. Cipto Mangunkusumo dan RSAB Harapan Kita dilakukan pada anak dengan gangguan neurodevelopmental yang menjalani terapi sejak Januari 2021-April 2023. Subjek dikelompokkan menjadi kelompok perlakuan mendapatkan implantasi eksosom, stimulasi auditori binaural beat, dan terapi konvensional, sedangkan kelompok kontrol hanya mendapatkan terapi konvensional. Luaran yang dinilai yaitu domain perkembangan BDI-2. Analisis univariat dan bivariat dilakukan sesuai kebutuhan.Hasil. Terdapat 25 subjek kelompok perlakuan dan 25 subjek kelompok kontrol. Tidak ada perbedaan karakteristik kedua kelompok sebelum perlakuan, kecuali domain motorik. Terdapat perbedaan usia developmental global maupun lima domain BDI-2 sebelum dan sesudah perlakuan pada kelompok perlakuan dan kontrol dengan median peningkatan usia developmental global masing-masing yaitu 7,5 dan 2,2 bulan. Tampak perbedaan peningkatan usia developmental global dan lima domain setelah perlakuan yang bermakna antara kelompok perlakuan dan kelompok kontrol.Kesimpulan. Implantasi eksosom dan stimulasi auditori binaural beat dapat meningkatkan usia developmental global dan lima domain perkembangan berdasarkan penilaian BDI-2 secara signifikan pada anak dengan gangguan neurodevelopmental.

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Background. Children with neurodevelopmental disorders require integrated therapeutic efforts to improve their quality of life. This study aimed to determine the effect of exosome therapy, binaural beat auditory stimulation, and conventional therapy on five BDI-2 domains in children with neurodevelopmental disorders.

Method. Retrospective cohort study using medical records at dr. Cipto Mangunkusumo National Center General Hospital and RSAB Harapan Kita was conducted for children with neurodevelopmental disorders who underwent therapy from January 2021 to April 2023. Subjects were grouped into a treatment group receiving exosome therapy, binaural beat auditory stimulation, and conventional therapy, while the control group only received conventional therapy. The BDI-2 developmental domains were assessed. Univariate and bivariate analysis were performed as needed.

Results. There were 25 subjects in the treatment group and 25 subjects in the control group. There were no differences in subjects’ characteristics between the two groups before treatment, except for the motor domain. There were differences in global and five BDI-2 domains developmental age before and after treatment in the treatment and control groups with a median increase in global developmental age, respectively, 7.5 and 2.2 months. There were significant differences in the increase of global and five domains developmental age after treatment between the treatment group and the control group.

Conclusion. Exosome therapy and auditory binaural beat stimulation improve global and five domains developmental age significantly based on BDI-2 assessment in children with neurodevelopmental disorders."