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Hasil Pencarian

Ditemukan 6 dokumen yang sesuai dengan query
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Adhitia
Abstrak :
ABSTRAK
Obat herbal sering digunakan sebagai alternatif pengobatan disamping obat konvensional. Termasuk oleh pengidap diabetes melitus (DM) tipe 2, penyakit kronis yang para pengidapnya seringkali tidak bisa terlepas dari penggunaan obat antidiabetes oral (ADO). Tujuan penelitian ini adalah untuk mengetahui pola penggunaan antidiabetes herbal pada pasien DM tipe 2 yang sedang berobat di puskesmas dan untuk mengetahui efek perseptif yang muncul serta mengetahui hubungan antara efek perseptif yang muncul dengan frekuensi penggunaan, jangka waktu penggunaan dan penggunaannya bersama ADO. Penelitian ini bersifat deskriptif analisis dengan metode potong lintang menggunakan kuesioner yang valid dan reliabel sebagai panduan wawancara. Penelitian dilakukan di 11 Puskesmas Kecamatan Kota Depok dari bulan Maret sampai Mei 2012. Responden diambil dengan metode consecutive sampling. Responden penelitian jumlahnya 101 orang, sebanyak 52,47 % menggunakan antidiabetes herbal dan 71,70 % pengguna antidiabetes herbal masih menggunakan ADO. Daun sirsak, daun salam dan kulit manggis adalah tiga terbanyak antidiabetes herbal yang digunakan. Efek perseptif paling banyak dirasakan adalah berkurangnya frekuensi buang air kecil sebanyak 24,53 % dan perasaan badan lebih enak sebanyak 18,87 % sedangkan 22,64 % responden tidak merasakan efek perseptif. Hanya 15,09 % responden merasakan efek samping perseptif berupa mual dan meningkatnya frekuensi buang air kecil. Tidak terdapat hubungan antara frekuensi, jangka waktu penggunaan dan penggunaan ADO dengan munculnya efek-efek perseptif.
ABSTRACT
Herbal medicine is often used as an alternative medication in addition to a conventional one. It is also the case of people suffering from type 2 diabetes mellitus (DM), a chronic disease in which the patients with this disease often cannot be detached from the use of oral antidiabetic drugs (OAD). The aim of this research are to investigate the pattern of the use of herbal antidiabetic agents to type 2 DM patients who are being treated in puskesmas, to identify the emerging perceptive effects, and to identify the relation between the perceptive effects with the frequency of use, period of use, as well as the combined consumption with OAD. The research is a descriptive analysis with a cross sectional method using a valid and reliable questionnaire as an interview guideline. The research was conducted at 11 Puskesmas Kecamatan Kota Depok from March to May 2012. The respondents were chosen by using consecutive sampling method. In the research, there are 101 respondents; 52.47% of them use herbal antidiabetic agents and 71.70% of the users of herbal antidiabetic agents still consume OAD. Soursop leaves, bay leaves, and mangosteen peel are three herbal antidiabetic agents that are mostly used. The perceptive effects that are primarily perceived are the decreased of the frequency of urination (24.53%) and the better feeling of the body (18.87%) whereas 22.64% of the respondents do not perceive perceptive effects. Only 15.09% of the respondents perceive the perceptive side effects such as nausea and the increasing frequency of urination. There is no correlation between the frequencies of use, the period of use, and the use of OAD with the emergence of perceptive effects.
Fakultas Farmasi Universitas Indonesia, 2012
S42169
UI - Skripsi Open  Universitas Indonesia Library
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Anies Monica Adhitia
Abstrak :
ABSTRAK
Peperomia pellucida L. Kunth telah dilaporkan memiliki beberapa aktivitas biologis seperti antihipertensi, antioksidan, anti-inflamasi. Bahan herbal rentan terhadap kontaminasi selama pengolahan dan penyimpanan yang dapat menurunkan kualitas, memperpendek masa simpan dan membahayakan konsumen. Iradiasi sinar gamma merupakan bentuk radiasi pengion yang umum digunakan untuk metode pengawetan. Penelitian ini bertujuan untuk menganalisis pengaruh iradiasi sinar gamma pada ekstrak etanol 70 % herba P. pellucida L. Kunth terhadap penghambatan aktivitas Angiotensin Converting Enzyme dan profil kromatografi lapis tipis. Herba kering P. pellucida L. Kunth diekstraksi dengan metode refluks menggunakan etanol 70 % dan kemudian diiradiasi sinar gamma pada dosis 2,5; 5; 7,5; dan 10 kGy. Setiap kelompok ekstrak yang diiradiasi sinar gamma tersebut diuji penghambatan aktivitas ACE secara in vitro menggunakan substrat 3-Hidroksibutilil-Glisil-Glisil-Glisin dari ACE Kit-WST Dojindo. Hasil uji menunjukan tidak ada perbedaan yang signifikan terhadap nilai persen penghambatan aktivitas ACE antara ekstrak noniradiasi dan ekstrak yang diiradiasi sinar gamma hingga dosis 10 kGy. Profil kromatografi lapis tipis untuk ekstrak yang diiradiasi identik dengan ekstrak noniradiasi baik yang diuji sesaat setelah iradiasi maupun setelah dua bulan penyimpanan. Perlakuan iradiasi sinar gamma hingga dosis 10 kGy tidak memengaruhi aktivitas penghambat ACE secara in vitro dan profil KLT pada ekstrak etanol 70 % herba P. pellucida L. Kunth.
ABSTRACT
Peperomia pellucida L. Kunth has been reported to have biological activities such as antihypertensive, antioxidant, anti-inflammatory. Herbal materials susceptible to contamination during processing and storage which can shortens their shelf life and direct health hazard to consumers. Gamma-irradiation is an ionic, non-thermal process that has been used as a method for preservation. This research aimed to analyze the effect of gamma irradiation on inhibition activity of Angiotensin Converting Enzyme of ethanol 70 % extract P. pellucida L. Kunth herbs and their chromatogram profiles of thin layer chromatography. Dried P. pellucida L. Kunth herbs were extracted by reflux method using ethanol 70 %. These extracts were irradiated with 60Co gamma rays applying doses of 2,5; 5; 7,5; dan 10 kGy. Each group of irradiated and non-irradiated extracts were tested for their inhibitory activity of ACE using an in vitro assay with ACE Kit-WST Dojindo. No significant differences were noted in the inhibition activity of ACE between non-irradiated extract and irradiated extracts. The type of chromatogram profiles in irradiated extracts were similar to those of non-irradiated extract either immediately after irradiation or after two months of storage. Treatment of gamma-rays irradiation up to 10 kGy did not affect the activity of ACE inhibitor in vitro and TLC profiles on ethanol 70 % extracts of the herb P. pellucida L. Kunth
2016
S63410
UI - Skripsi Membership  Universitas Indonesia Library
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Alfan Lesmana Adhitia
Abstrak :
Tren sistem registrasi rekening online semakin meningkat terutama saat pandemi Covid-19 pada bank konvensional/syariah. Perkembangan tersebut menandakan semakin tinggi intensi adopsi sistem registrasi rekening online sehingga perlu diketahui faktor-faktor yang dapat berpengaruh. Teori yang digunakan adalah Push-Pull-Mooring (PPM). Push factor terdiri dari perceived severity (PS), perceived vulnerability (PV), serta perceived inefficiency (PI). Pull factor terdiri dari perceived ease of use (PEOU), perceived usefulness (PU), serta perceived privacy and security (PPS). Mooring factor terdiri dari institution-based trust (IBT), perceived innovativeness (PIO), serta social influence (SI). Usia dan tingkat pendidikan diteliti sebagai faktor moderasi. Pendekatan menggunakan explanatory sequential mixed methods dengan kuantitatif covariance-based structural equation modelling (CB-SEM) yang dilanjutkan kualitatif. Hasil penyebaran kuesioner daring 404 responden valid dan wawancara 9 responden. Hasil analisis membuktikan bahwa faktor PS dan PV mendorong adopsi, faktor PEOU dan PU menarik adopsi, serta semua mooring factor berpengaruh terhadap adopsi. Namun, PI dan PPS tidak memengaruhi adopsi. Usia terbukti memoderasi hubungan antara PV, PU, PPS, dan IBT dengan adopsi, sedangkan tingkat pendidikan dapat moderasi antara PV, PEOU, dan SI dengan adopsi. Penelitian ini diharapkan dapat memperkaya penelitian terdahulu dan bank sebagai penyedia sistem registrasi rekening online dapat mengatur strategi bisnis yang tepat. ......The trend of online account registration at conventional/sharia banks is increasing yearly, especially during the Covid-19 pandemic. It indicates the intention to adopt an online account registration system is increasing, so it’s necessary to know the factors that influence it. This research uses Push-Pull-Mooring (PPM) theory. Push factors are perceived severity (PS), perceived vulnerability (PV), perceived inefficiency (PI). Pull factors are perceived ease of use (PEOU), perceived usefulness (PU), perceived privacy and security (PPS). Mooring factors are institution-based trust (IBT), perceived innovativeness (PIO), social influence (SI). Age and education level were investigated as moderating factors. This research was conducted using an explanatory sequential mixed methods approach with Covariance Based Structural Equation Modeling (CB-SEM) for quantitative and followed by qualitative. The results of online questionnaires were 404 valid respondents and interviews with 9 respondents. The analysis result is prove that PS and PV push the adoption, PEOU and PU pull the adoption, and all mooring factors affect the adoption. However, PI and PPS do not affect the adoption. Age is proven to moderate the relationship between PV, PU, PPS, and IBT with the adoption, while education level moderate between PV, PEOU, and SI with the adoption. This research is expected to enrich previous research and help banks to organize the proper business strategy.
Depok: Fakultas Ilmu Komputer Universitas Indonesia, 2022
S-pdf
UI - Skripsi Membership  Universitas Indonesia Library
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Anies Monica Adhitia
Abstrak :
Praktik Kerja Profesi Apoteker di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo bertujuan untuk menganalisis peran dan fungsi Apoteker serta kegiatan kefarmasian di Instalasi Farmasi Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo dan mengetahui kegiatan yang dilakukan di instalasi/unit penunjang yaitu Instalasi Sterilisasi Pusat. Selain itu juga agar memperoleh pengetahuan dan wawasan tentang segala aspek yang terkait kegiatan farmasi klinis di Rumah Sakit Umum Pusat Nasional RSUPN Dr. Cipto Mangunkusumo. Tugas khusus yang diberikan bertujuan untuk mengevaluasi waktu tunggu pasien rawat jalan di satelit farmasi Rumah Sakit Umum Pusat Nasional RSUPN Dr. Cipto Mangunkusumo. ...... Profession Internship at Dr. Cipto Mangunkusumo National General Hospital aimed to analyze the roles and fuctions of pharmacist, and pharmacy activities in Pharmacy Installation Dr. Cipto Mangunkusumo National General Hospital as well as to know activities of installation support unit, namely the Centralized Sterilization Supply Department. Moreover, profession Internship at Dr. Cipto Mangunkusumo National General Hospital aimed to gain knowledge and insight into everything related aspects of clinical pharmacy activities Dr. Cipto Mangunkusumo National Center General Hospital. In additions, the purpose of the special task is to evaluate Patients rsquo Response to Waiting Time in an Out Patient Pharmacy at Dr. Cipto Mangunkusumo National General Hospital
Depok: Fakultas Farmasi Universitas Indonesia, 2017
PR-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Anies Monica Adhitia
Abstrak :
ABSTRAK
Apotek adalah sarana pelayanan kefarmasian tempat dilakukannya praktik kefarmasian oleh apoteker. Praktik Kerja Profesi Apoteker di Apotek Kimia Farma bertujuan untuk menganalisis gambaran umum mengenai kegiatan pelayanan kefarmasian di apotek, serta menganalisis peran dan fungsi apoteker di apotek dalam aspek professional, yang mencakup ilmu kefarmasian dan pelayanan kefarmasian, serta aspek manajerial yang mencakup pengelolaan perbekalan farmasi dan administrasi keuangan apotek.
ABSTRACT
Pharmacy is a pharmaceutical care facility, where the pharmacist can do their responsibility. Profession Internship at Kimia Farma Pharmacy aimed to analyze the activities of pharmaceutical care in pharmacy, as well as understanding the roles and functions of pharmacists from the professional aspects, pharmaceutical care, as well as managerial aspects such as management of pharmaceuticals and medical supplies and financial administration.
2017
PR-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Anies Monica Adhitia
Abstrak :
ABSTRAK
Kegiatan praktik kerja profesi di Puskesmas Kecamatan Senen dilakukan agar calon apoteker menganalisis peranan, tugas, dan tanggung jawab apoteker di puskesmas sesuai dengan ketentuan standar pelayanan farmasi di puskesmas. Selain itu, diharapkan agar calon apoteker dapat melakukan praktik langsung pelayanan kefarmasian yang dilakukan di puskesmas yang mencakup pengelolaan sediaan farmasi dan pelayanan farmasi klinik. Pengelolaan sediaan farmasi di puskesmas meliputi perencanaan, pengadaan, permintaan, pendistribusian, pengendalian, pemantauan dan pencatatan atau pelaporan sediaan farmasi dan alat kesehatan. Sedangkan pelayanan farmasi klinik yang dilakukan mencakup pengkajian resep, pelayanan informasi obat, konseling, dan pemantauan terapi obat serta efek samping obat.
ABSTRACT
Profession Internship in Puskesmas Kecamatan Senen aimed to analyze the role, duties and responsibilities of pharmacists in puskesmas in accordance with the provisions of the pharmaceutical care standard in puskesmas. Moreover, the prospective pharmacist learned about pharmaceutical care management of pharmaceuticals and medical supplies and clinical pharmacy. Managerial aspects such as planning, procurement, demand, distribution, control, and monitoring of pharmaceuticals and medical supplies. While the clinical pharmacy such as prescription assessment, drug information, counseling, and monitoring of drug therapy and drug side effects.
2017
PR-pdf
UI - Tugas Akhir  Universitas Indonesia Library