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Hasil Pencarian

Ditemukan 28 dokumen yang sesuai dengan query
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Tamas Balla, editor
In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Volume II extends into the role of phosphoinositides in membrane organization and vesicular traffic. Endocytosis and exocytosis are modulated by phosphoinositides, which determine the fate and activity of integral membrane proteins. Phosphatidylinositol(4,5)-bisphosphate is a...
Dordrecht: [, Springer], 2012
e20417495
eBooks  Universitas Indonesia Library
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Tamas Balla, editor
In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases...
Dordrecht: [Springer, ], 2012
e20417501
eBooks  Universitas Indonesia Library
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Jeffrey E. Green, editor
Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which...
New York: [, Springer], 2012
e20417619
eBooks  Universitas Indonesia Library
cover
Naiara Rodriguez-Ezpeleta, editor
Next generation sequencing is revolutionizing molecular biology. Owing to this new technology it is now possible to carry out a panoply of experiments at an unprecedented low cost and high speed. These go from sequencing whole genomes, transcriptomes and small non-coding RNAs to description of methylated regions, identification protein –...
New York: [Springer, ], 2012
e20417671
eBooks  Universitas Indonesia Library
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Paolo Sassone-Corsi, editor
The focus of this volume is on critical epigenetic regulation and chromatin remodeling events that occur in the nervous system and on the presumed mechanisms that operate within neurons to translate them into long-lasting neuronal responses.Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the...
Berlin: [Springer, ], 2012
e20417764
eBooks  Universitas Indonesia Library
cover
Despite a half century of structural, biophysical and biochemical investigations of ribonucleic acids, they are still mysterious. RNAs stand at fertile crossroads of disciplines, integrating concepts from genomics, proteomics, dynamics as well as biochemistry and molecular biology. From 20 years it is clear, that genetic regulation of eukaryotic organisms has...
Berlin: Springer, 2012
e20418025
eBooks  Universitas Indonesia Library
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John F. Cryan, editor
This book covers a wide array of topics relevant to behavioral genetics from both a preclinical and clinical standpoint. Topics covered range from technical advances in genetic analysis in humans and animals to specific descriptions of advances in schizophrenia, attention disorders, depression and anxiety disorders, autism, aggression, neurodegeneration and neurodevelopmental...
Berlin: [Springer, ], 2012
e20417766
eBooks  Universitas Indonesia Library
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Hutson, John M., editor
The rapid advances in medicine over the last 50 years have totally changed the outlook for children with disorders of sex development (DSD), but there is still much to learn. This book crystallizes the combined experience of a leading dedicated unit over 25 years in delivering expert medical and surgical...
Berlin : Springer, 2012
e20425898
eBooks  Universitas Indonesia Library
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