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Ditemukan 31 dokumen yang sesuai dengan query
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Kondratyev, V.
Moscow: Foreign Languages Publishing House, 1967
541.2 KON s
Buku Teks  Universitas Indonesia Library
cover
Abstrak :
This book provides basic principles of multivalent interactions found in biological systems as well as an up to date and thorough coverage in design concepts, syntheses, and biological activities of multivalent molecules. It contains practical examples of synthetic multivalent molecules in chemistry, biology, and medicine. It can be used as both a textbook for students and a reference book for libraries and professionals. It includes detailed case studies and fills a void in current literature through its devotion solely to multivalent molecules.
Hoboken, New Jersey: John Wiley & Sons, 2004
e20394637
eBooks  Universitas Indonesia Library
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Hinchliffe, Alan
England: John Wiley & Sons, 2005
541.22 HIN m
Buku Teks  Universitas Indonesia Library
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Alice Tamara
Abstrak :
Latar Belakang: ALDH1A1 merupakan gen yang meregulasi diferensiasi dan proliferasi sel dengan jalur asam retinoat. Telah dikenal sebagai gen pluripotensi, ALDH1A1 dapat ditemukan pada Cancer Stem Cell (CSC) dan Mesenchymal Stem Cells (MSC) seperti Adipose-derived Stem Cell (ASC) dan Umbilical Cord Stem Cells (UCSC). Studi ini bertujuan untuk membandingkan relatif ekspresi gen ALDH1A1 pada ASC dan UCSC terhadap ALDH+ Breast CSC (BCSC). Metode: One-step qRT-PCR dilakukan untuk mendeteksi ekspresi mRNA ALDH1A1 pada ekstraksi RNA ASC, UCSC, dan BCSC. Hasil PCR dianalisis dengan BCSC menjadi ekspresi relatif setelah data dinormalisasikan oleh gen 18S. Hasil: Ekspresi gen ALDH1A1 relatif ditemukan lebih tinggi secara signifikan pada ASC dibandingkan UCSC. Sementara itu, ALDH1A1 lebih rendah diekspresikan pada MSC dibandingkan BCSC. Konklusi: ASC memiliki kemampuan pluripotensi lebih baik dibandingkan UCSCs pada aspek ALDH1A1. Hal ini disebabkan oleh kemampuan spesifik yang dimiliki ALDH1A1 untuk proliferasi dan diferensiasi ASC. ......Background: ALDH1A1 is a gene which regulates the cell differentiation and proliferation through retinoic acid pathway. Being a renowned pluripotent gene, ALDH1A1 could be found in both cancer stem cells (CSCs) and human Mesenchymal Stem Cells (MSCs) such as Adipose-derived Stem Cells (ASCs) and Umbilical Cord Stem Cells (UCSCs). This research aimed to compare the expression of ALDH1A1 gene in ASCs and UCSCs relatively towards ALDH+ Breast CSCs (BCSCs). Method: A one-step qRT-PCR was done to detect the mRNA levels of ALDH1A1 gene in the RNA extraction of ASCs, UCSCs, and BCSCs. The PCR result was analyzed into relative expression with BCSCs, after being normalized with housekeeping 18S gene. Results: The expression of ALDH1A1 was found to be significantly higher in ASCs than UCSCs, relatively. Furthermore, ALDH1A1 gene was expressed lower in MSCs than BCSCs. Conclusion: ASCs are discovered to be better in pluripotent capability than UCSCs in the aspect of ALDH1A1. This finding signifies the specific role of ALDH1A1, resulting in contribution of differentiation and proliferative capability to ASCs.
Depok: Fakultas Kedokteran Universitas Indonesia, 2018
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UI - Skripsi Membership  Universitas Indonesia Library
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Berne, Bruce J.
New York : John Wiley & Sons, 1976
535.43 BER d
Buku Teks  Universitas Indonesia Library
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Walton, Anne
New York: Ellis Horwood, 1978
539.12 WAL m
Buku Teks  Universitas Indonesia Library
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Beck, Raymond W.
Minnesota: Burgess, 1976
570 BEC s I
Buku Teks  Universitas Indonesia Library
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Hameka, Hendrik F.
London : Addison-Wesley, 1965
541.383 HAM a
Buku Teks  Universitas Indonesia Library
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Ibnu Shohib
Solo: Azka Pressindo, 2017
540 IBN a
Buku Teks  Universitas Indonesia Library
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McKnown, Robin
"New York:: Holiday House, 1962
541.38 MCK f
Buku Teks  Universitas Indonesia Library
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