Hasil Pencarian  ::  Simpan CSV :: Kembali

"Kontraktur leher sebagian besar timbul akibat komplikasi luka bakar sebelumnya atau akibat trauma asam atau basa di daerah leher. Kontraktur leher atau kontraktur mentostemal ini sering terjadi dan merupakan salah satu tantangan bagi ahli bedah plastik dan rekonstruksi terutama ahli bedah plastik Indonesia yang jumlahnya masih sedikit.

---

Neck contractures mostly arise as a result of complications previous burns or as a result of acid trauma or alkaline in the neck area. Neck contractures or mentostemal contractures often occur and are one of the challenges for plastic and reconstructive surgeons, especially Indonesian plastic surgeons who are still few in number."

"Latar belakang. Infeksi Cytomegalovirus (CMV) kongenital merupakan faktor non genetik yang paling sering menjadi penyebab terjadinya ketulian sensorineural pada bayi dan anak. Infeksi CMV dapat memberikan tanda dan gejala namun dapat juga tidak memberikan gejala pada yang terinfeksi. Ketulian akibat infeksi CMV kongenital tidak memiliki konfigurasi patognomik sehingga penelitian terhadap infeksi CMV kongenital pada pendengaran masih sangat diperlukan. Pengetahuan tentang ketulian akibat infeksi CMV kongenital di negara-negara luar yang semakin berkembang membuat peneliti ingin mengetahui bagaimana gambaran gangguan pendengaran anak dengan infeksi CMV kongenital di Indonesia, khususnya RS Cipto Mangunkusumo. Tujuan. Mengetahui gambaran gangguan pendengaran pada anak usia 0-5 tahun yang mengalami infeksi CMV kongenital berdasarkan pemeriksaan DPOAE dan BERA click. Metode. Penelitian cross sectional ini dilakukan di RSUPN Cipto Mangunkusumo pada bulan November 2015-Mei 2016 pada 27 subjek anak usia 0-5 tahun yang telah didiagnosa terinfeksi CMV kongenital. Hasil. Gambaran gangguan fungsi pendengaran pada subjek anak usia 0-5 tahun dengan infeksi CMV kongenital berdasarkan pemeriksaan DPOAE dan BERA click pada unit telinga adalah tuli sensorineural sebanyak 58,0%. Didapatkan hubungan yang bermakna secara statistik (p = 0,002) antara keterlambatan tumbuh kembang dengan terjadinya tuli sensorineural. Keterlambatan tumbuh kembang memiliki risiko 6,57 (CI 95%; 1,88 – 22,87) kali lebih besar dibandingkan pasien dengan tumbuh kembang normal untuk mengalami gangguan pendengaran sensorineural.

---

Background. Congenital cytomegalovirus (CMV) infection is a non genetical factor that is most commonly found asthe etiology of sensorineural hearing loss in infants and children. CMV does not always cause signs and symptoms.Hearing loss caused by CMV infection does not have a patognomonic configuration hence further research is needed. The development on the knowledge on hearing loss caused by congenital CMV infection in foreign countriesis the reason the author decide to investigate on the profile of hearing impairment in children with congenital CMV infection in Indonesia, especially in Cipto Mangunkusumo Hospital.

Purpose. To know the profile of hearing impairment in children age 0-5 years old with congenital CMV infection based on DPOAE and BERA click.

Methods.This cross-sectional study was conducted in Cipto Mangunkusum Hospital since November 2015-May 2016 in 27 subjects, children age 0-5 years old with congenital CMV infection.

Results. Hearing impairment in subjects children age 0-5 years old with congenital CMV inefection, based on DPOAE and BERA click on ear unitsis 58,0% with sensorineural hearing loss. There is a significant relationship (p=0,002) between developmental delay and the incidence of sensorineural hearing loss. Developmental delay has a 6,57 times (CI 95%; 1,88 – 22,87) higher the risk for subjects to experience sensorineural hearing loss compared to normal development."

"ABSTRAK Pendahuluan: Biopsi jarum inti dianggap memiliki hasil akurasi yang samadengan biopsi terbuka dan telah menjadi prosedur rutin untuk menegakkandiagnosis lesi muskuloskeletal. Namun demikian uji diagnostik biopsi jarum intidi Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo (RSUPN CM)belum dilaporkan. Tujuan dari analisis retrospektif ini adalah untuk mendapatkannilai ketepatan diagnosis biopsi jarum inti pada lesi muskuloskeletal.Metode: Dari Januari 2011 hingga Agustus 2015, semua pasien dengan lesi muskuloskeletal di RSUPN CM yang menjalani biopsi jarum inti dan eksisi tumor diidentifikasi dan diambil datanya. Ketepatan diagnosis dianalisis baik untukkesimpulan histopatologi maupun kesimpulan clinical pathology conference(CPC).Hasil: Sebanyak 86 sampel dikumpulkan dalam penelitian ini. Ketepatandiagnosis biopsi jarum inti dibandingkan dengan spesimen pasca eksisi adalah74,4%. Setelah dilakukan CPC, nilai ketepatan menjadi 83,7% dengan sensitivitas98%, spesifisitas 59%, NDP 87%, NDN 93% (p = 0.00). Ketepatan biopsi jaruminti setelah pulasan imunohistokimia naik menjadi 84,9% (p = 0,438). Ketepatanuntuk membedakan lesi jinak dan ganas adalah 97,1% (jinak) dan 82,7% (ganas)(p = 0.00). Ketepatan untuk membedakan lesi primer dan metastasis adalah 97,2%(primer) dan 85,7% (metastasis) (p = 0.00).Diskusi: Kami mendapatkan nilai ketepatan biopsi jarum inti yang sedikit lebihrendah karena dalam penelitian ini dituntut untuk membuat diagnosis sampaitingkat morfologi (ICD O dan ICD X). Namun demikian, dengan modalitas lainseperti imunohistokimia dan kesimpulan CPC, ketepatan menjadi meningkat.Ketepatan diagnosis untuk membedakan lesi jinak-ganas dan primer-metastasis tinggi. Biopsi jarum inti direkomendasikan untuk penegakkan diagnosis lesi muskuloskeletal.ABSTRACT Introduction: Core needle biopsy is considered to have similar results with openbiopsy in accuracy and already become a routine procedure to establish thediagnosis of musculoskeletal lesion. However, diagnostic test of core needlebiopsy application in Cipto Mangunkusumo Hospital has not been reported.Therefore, the aim of this retrospective analysis was to attain the accuracy ofmusculoskeletal lesion diagnosis using core needle biopsy. Methods: From January 2011 to August 2015, all patients with musculoskeletal lesion in Cipto Mangunkusumo Hospital underwent core needle biopsy andsubsequent tumour excision were indentified and enrolled. Diagnostic accuracywere calculated for both histopathology and clinical pathology conference (CPC)conclusion.Results: A total of 86 samples were indentified and enrolled in this study. Theaccuracy of core needle biopsy compared to subsequent excision is 74.4%. WithCPC conclusion, the accuracy is 83.7% with sensitivity 98%, specificity 59%,PPV 87%, NPV 93% (p=0.00). The accuracy with immunohistochemistry is84.9% (p=0.438). The accuracy to distinguish benign and malignant lesion is 97.1% (benign) and 82.7% (malignant) (p= 0.00). The accuracy to distinguishprimary and metastatic lesion is 97,2% (primary) and 85,7% (metastatic) (p=0.00). Discussion: We found slightly inferior results for core needle biopsy accuracycompared to literature due to high specificity diagnosis obligatory (ICD O andICD X morphology) in our study. However, with other modalities such asimmunohistochemistry and CPC, the accuracy is increased. The accuracy todistinguish between benign vs malignant and primary vs metastatic lesion is high.Core needle biopsy is recommended to establish diagnosis for selected musculoskeletal lesions.;Introduction: Core needle biopsy is considered to have similar results with openbiopsy in accuracy and already become a routine procedure to establish thediagnosis of musculoskeletal lesion. However, diagnostic test of core needlebiopsy application in Cipto Mangunkusumo Hospital has not been reported.Therefore, the aim of this retrospective analysis was to attain the accuracy ofmusculoskeletal lesion diagnosis using core needle biopsy. Methods: From January 2011 to August 2015, all patients with musculoskeletal lesion in Cipto Mangunkusumo Hospital underwent core needle biopsy andsubsequent tumour excision were indentified and enrolled. Diagnostic accuracywere calculated for both histopathology and clinical pathology conference (CPC)conclusion.Results: A total of 86 samples were indentified and enrolled in this study. Theaccuracy of core needle biopsy compared to subsequent excision is 74.4%. WithCPC conclusion, the accuracy is 83.7% with sensitivity 98%, specificity 59%,PPV 87%, NPV 93% (p=0.00). The accuracy with immunohistochemistry is84.9% (p=0.438). The accuracy to distinguish benign and malignant lesion is 97.1% (benign) and 82.7% (malignant) (p= 0.00). The accuracy to distinguishprimary and metastatic lesion is 97,2% (primary) and 85,7% (metastatic) (p=0.00). Discussion: We found slightly inferior results for core needle biopsy accuracycompared to literature due to high specificity diagnosis obligatory (ICD O andICD X morphology) in our study. However, with other modalities such asimmunohistochemistry and CPC, the accuracy is increased. The accuracy todistinguish between benign vs malignant and primary vs metastatic lesion is high.Core needle biopsy is recommended to establish diagnosis for selected musculoskeletal lesions.;Introduction: Core needle biopsy is considered to have similar results with openbiopsy in accuracy and already become a routine procedure to establish thediagnosis of musculoskeletal lesion. However, diagnostic test of core needlebiopsy application in Cipto Mangunkusumo Hospital has not been reported.Therefore, the aim of this retrospective analysis was to attain the accuracy ofmusculoskeletal lesion diagnosis using core needle biopsy. Methods: From January 2011 to August 2015, all patients with musculoskeletal lesion in Cipto Mangunkusumo Hospital underwent core needle biopsy andsubsequent tumour excision were indentified and enrolled. Diagnostic accuracywere calculated for both histopathology and clinical pathology conference (CPC)conclusion.Results: A total of 86 samples were indentified and enrolled in this study. Theaccuracy of core needle biopsy compared to subsequent excision is 74.4%. WithCPC conclusion, the accuracy is 83.7% with sensitivity 98%, specificity 59%,PPV 87%, NPV 93% (p=0.00). The accuracy with immunohistochemistry is84.9% (p=0.438). The accuracy to distinguish benign and malignant lesion is 97.1% (benign) and 82.7% (malignant) (p= 0.00). The accuracy to distinguishprimary and metastatic lesion is 97,2% (primary) and 85,7% (metastatic) (p=0.00). Discussion: We found slightly inferior results for core needle biopsy accuracycompared to literature due to high specificity diagnosis obligatory (ICD O andICD X morphology) in our study. However, with other modalities such asimmunohistochemistry and CPC, the accuracy is increased. The accuracy todistinguish between benign vs malignant and primary vs metastatic lesion is high.Core needle biopsy is recommended to establish diagnosis for selected musculoskeletal lesions."

"Latar belakang: Patensi jalan napas merupakan hal paling penting dalam manajemen pasien di dalam kamar operasi maupun di luar kamar operasi. Kegagalan ataupun keterlambatan dalam manajemen jalan napas akan membawa dampak yang buruk terhadap morbiditas maupun mortalitas pasien. Prediksi kesulitan jalan napas dapat dilakukan dengan penilaian klinis maupun pemeriksaan penunjang. Cormack-Lehane grading telah lama digunakan sebagai prediksi kesulitan laringoskopi melalui visualisasi laring. Menurut penelitian yang sudah dilakukan oleh W Yao dan Bin Wang, dikatakan ukuran lebar lidah diatas 6.0 cm dapat menjadi prediksi terjadinya kesulitan intubasi. Salah satu faktor yang menyebabkan kesulitan intubasi adalah kesulitan laringoskopi yang ditandai dengan Cormack Lehane Grading ≥ 3. Penelitian ini bertujuan untuk mencari apakah terdapat hubungan ukuran lebar lidah dengan kesulitan laringoskopi yang ditandai dengan Cormack Lehane Grading.Metode: Penelitian observasional prospektif dengan desain cross sectional ini dilakukan di Instalasi Bedah Pusat, CCC, dan Kirana RSUPN Cipto Mangunkusumo pada bulan Juli sampai September 2022. Populasi subjek adalah pasien yang akan menjalani pembedahan dengan pembiusan total dan menggunakan ETT. Ketebalan lidah diukur dengan menggunakan ultrasonografi. Penilaian Cormack Lehane Grading dilakukan melalui visualisasi laring pada saat laringoskopi dan sebelum dilakukan intubasi endotrakeal.Hasil: Kelompok subjek dengan karakteristik sulit intubasi berdasarkan Cormack Lehane Grading (≥3) terbukti memiliki rerata ketebalan lidah yang lebih tebal dibandingkan kelompok mudah intubasi. Kelompok sulit intubasi juga terbukti memiliki Modified Mallampati Score yang lebih tinggi.Kesimpulan: Ketebalan lidah dan Modified Mallampati Score berhubungan dengan sulit intubasi berdasarkan Cormack Lehane grading, sehingga dapat digunakan sebagai prediktor kesulitan jalan napas.

---

Background: Airway patency is a critical variable to maintain, either in perioperative or emergency setting. Failure or delay in airway management is associated with life-threatening complications. Prediction of difficult airway management can be done through bedside clinical examination and/or further investigations. Cormack Lehane grading has long been known as a parameter to assess difficult airway by visualization of the larynx. According to W Yao and Bin Wang, tongue thickness > 6.0 cm may be a predictor of difficult airway. One of the factors associated with difficult-to-intubate patients is difficult laryngoscopy as indicated by Cormack Lehane grading ≥ 3. This study aimed to investigate the correlation between tongue thickness and difficult laryngoscopy assessed through Cormack Lehane Grading.

Methods: This prospective observational study was conducted in Central Surgery Unit, CCC, and Kirana Unit of Cipto Mangunkusumo General Hospital in the period of July to September 2022. This study involved patients undergoing surgical interventions with general anesthesia and endotracheal intubation. Tongue thickness of each subject was assessed by ultrasonography. The assessment of Cormack Lehane grading in each subject was conducted through visualization of the larynx during laryngoscopy and prior to tracheal intubation.

Results: Difficult-to-intubate group characterized by Cormack Lehane grading ≥3 was associated with thicker tongue and higher Modified Mallampati score.

Conclusion: Tongue thickness and modified Mallampati score were associated with difficult laryngoscopy and endotracheal intubation based on Cormack Lehane grading. Therefore, tongue thickness may serve as a potential predictor of difficult airway."

"Infeksi CMV merupakan penyebab infeksi kongenital tersering di dunia yang menyebabkan kematian maupun kecacatan permanen misalnya keterlambatan perkembangan, gangguan pendengaran dan penglihatan. Prevalensi CMV dipengaruhi oleh letak geografis, status sosial ekonomi dan etnis. Prevalensi CMV kongenital di Amerika berkisar 0,5-1 , sementara di Negara berkembang 0,6-6,1 . Di Indonesia belum terdapat data prevalensi CMV kongenital. Penelitian ini adalah penelitan potong lintang untuk mengetahui prevalensi infeksi CMV pada neonatus yang lahir di RSCM. Penelitian dilakukan dari bulan Oktober 2016 sampai April 2017. Pemilihan subjek penelitian dilakukan dengan teknik consecutive sampling tanpa randomisasi, mengikutsertakan semua neonatus berusia kurang dari 21 hari. Sampel urin dilakukan polymerase chain reaction PCR dan sequencing. Neonatus yang terinfeksi akan menjalani skrining kelainan fungsi pendengaran, penglihatan dan USG kepala serta pemantauan selama 6 bulan. Sebanyak 12 dari 205 5,9 subjek penelitian, terinfeksi CMV atas dasar pemeriksaan PCR dan sequencing CMV urin. Sebanyak 5 dari 12 bayi yang terinfeksi CMV menjalani perawatan dengan diagnosis sepsis dan prematuritas. Satu orang bayi yang terinfeksi CMV meninggal. Prevalensi infeksi CMV pada neonatus di RS Cipto Mangunkusumo adalah 5,9 . Sebanyak 2 subjek merupakan infeksi simtomatik, sementara 10 subjek asimtomatik. Manifestasi klinis yang terlihat adalah gejala sistemik berupa viral-like sepsis, kolestasis, trombositopenia, dan gejala neurologis berupa ventrikulomegali.

---

CMV infection is the commonest cause of congenital infection, causing death or permanent disability such as delayed growth, hearing and sight problems. Prevalence of CMV infection is influenced by geographical location, socio economic status, and ethnicity. Prevalence of CMV infection in the US is around 0.5 1 , while in the developing countries varies from 0.6 6.1 . In Indonesia the prevalence of congenital CMV infection is unknown. This study is a cross sectional study to determine the prevalence of congenital CMV infection among neonates in Cipto Mangunkusumo hospital, held from October 2016 to April 2017. Subjects were recruited through consecutive sampling without randomization, from all neonates below 21 days old. Urine sample are collected for polymerase chain reaction PCR and sequencing of CMV. Infected neonates were screened for hearing and sight problems, brain ultrasound, and given a follow up program for 6 months. Twelve out of 205 subjects 5.9 were infected with CMV according to urine PCR and sequencing results. Five of them underwent hospitalization in the NICU due to sepsis and prematurity. One died during follow up. Prevalence of congenital CMV infection in Cipto Mangunkusumo hospital is 5.9 . Two subjects were considered as symptomatic infection, while the other ten asymptomatic. Clinical manifestation were systemic symptoms such as viral like sepsis, cholestasis, thrombocytopenia, and ventriculomegaly."

"Tujuan : Untuk mengetahui karakteristik penderita kanker serviks di Departemen Patologi Anatomi RSCM pada tahun 2006Metode : Merupakan penelitian cross-sectional. Telah dilakukan evaluasi terhadap 554 penderita kanker serviks yang datang ke Departemen Patologi Anatomi. Namun hanya 465 orang yang memenuhi kriteria inklusi. Data yang dikumpulkan adalah usia, stadium dan gambaran histopatologiHasil : terdapat 465 kasus baru penderita kanker serviks di Departemen Patologi Anatomi pada tahun 2006 dengan rata-rata usia 49±8,708 tahun. Usia termuda 30 tahun dan usia tertua 78 tahun. Jumlah penderita terbanyak berada pada rentang usia 45-49 tahun yaitu 103 orang. Penderita kanker serviks terbanyak didiagnosis pada stadium IIIB dan gambaran histopatologi terbanyak adalah karsinoma sel skuamosa.Kesimpulan : terdapat korelasi lemah antara usia dengan stadium pada penderita kanker serviks di Departemen Patologi Anatomi RSCM Jakarta tahun 2006

---

Purpose : To know the characteristic of cervical cancer patients in Pathology Anatomy Department Cipto Mangunkusumo hospital

Method : Cross-sectional study. 554 cervical cancer patiens was evaluated in Pathology Anatomy Department Cipto Mangunkusumo hospital but only 465 patients who are included in this study. Data which are collected are age, stadium, and histopathology findings

Result : There are 465 new cases of cervical cancer in Pathology Anatomy Department Cipto Mangunkusumo hospital in 2006 with mean age 49±8,708 years old. The yougest age is 30 yeras old and the oldest age is 78 years old. The greatest number of the cervical cancer cases are between 45 and 49 yeras old. Stadium IIIB is found very commonly in cervical cancer patients and the most often of histopathology findings are carcinoma cell squamosa

Conclusion : There are weakness correlation of stadium and age in cervical cancer patients in Pathology Anatomy Department Cipto Mangunkusumo hospital in 2006"

"This book is based on results of the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new data and additional chapters. It is hoped that it will raise awareness of this underestimated condition and promote cooperative efforts to work towards a cure. Up to date information is provided on the epidemiology, biology, and pathology of the disease. The principles and specifics of treatment are explored in detail. The indications for and techniques of radiotherapy, minimally invasive treatments and open surgery are fully explained. The role of physical therapy is considered as well as the care of relapse and complications. The treatment of Ledderhose’s disease and Peyronie’s disease is also discussed. This book provides invaluable information for hand surgeons, podiatrists, orthopedists, radiation therapy specialists and general practitioners. It will help to foster an interdisciplinary approach to the understanding and management of this debilitating disorder."