Hasil Pencarian  ::  Simpan CSV :: Kembali

"Vaksinasi terhadap Virus Corona (SARSCov2) dianggap sebagai upaya penting dalam mengendalikan pandemi COVID-19 dan mempercepat pemulihan aktivitas ekonomi. Bukti empiris mengenai pengaruh vaksinasi terhadap kesehatan dan ekonomi pada tingkat kabupaten/kota di Indonesia masih terbatas. Penelitian ini bertujuan untuk menganalisis pengaruh vaksinasi terhadap hasil kesehatan dan kondisi ekonomi masyarakat. Analisis dilakukan menggunakan metode fixed effect dengan data set panel bulanan mengenai vaksinasi dan berbagai hasil kesehatan (positivity rate dan recovery) serta data set tahunan tentang vaksinasi dan kondisi ekonomi masyarakat yang diukur melalui pengeluaran per kapita pada 514 kabupaten/kota di Indonesia selama periode Januari 2021 hingga Desember 2022. Hasil estimasi menunjukkan bahwa vaksinasi dosis pertama berpengaruh signifikan terhadap penurunan positivity rate, peningkatan jumlah pemulihan kasus (recovery), dan juga terhadap peningkatan pengeluaran per kapita. Analisis lebih lanjut menunjukkan bahwa vaksinasi dosis kedua mampu mempertahankan keberlanjutan efek positif terhadap hasil kesehatan dan kondisi ekonomi masyarakat.

---

Vaccination against the Coronavirus (SARSCov2) is considered an important effort in controlling the COVID-19 pandemic and accelerating the recovery of economic activity. Limited empirical evidence exists regarding the effect of vaccination on health and the economy at the district level in Indonesia. This research examines the effect of the COVID-19 vaccination on health outcomes and the economic conditions of society. The analysis was carried out using the fixed effect method with panel monthly data of vaccinations and various health outcomes (positivity rate and case recoveries) and annual data of vaccinations and economic conditions of society as measured by expenditure per capita in about 514 districts in Indonesia during the period January 2021 to December 2022. The estimation results show that the first dose of vaccination has a significant effect on reducing the positivity rate, increasing the number of case recoveries, and also increasing expenditure per capita. Further analysis shows that the second dose of vaccination is able to maintain a sustainable positive effect on health outcomes and the economic condition of society."

"COVID-19 telah menginfeksi ratusan juta orang dan menyebabkan kematian jutaan orang di seluruh dunia. Vaksinasi diharapkan dapat mengurangi insiden penyakit, tingkat mortalitas, maupun keparahan penyakit. Sehingga peneliti ingin mengetahui seberapa besar efek vaksinasi dalam melindungi pasien COVID-19 terhadap penyakit COVID-19 yang berat dan kematian COVID-19. Penelitian ini merupakan penelitian kohort retrospektif yang menggunakan data dari database NAR COVID-19 dan Dashboard KPCPEN Dinkes Kota Depok mulai tanggal 8 Mei 2020 hingga 20 Februari 2023 yang dianalisis menggunakan regresi logistik. Peneliti menemukan bahwa kelompok usia terbesar adalah usia 31-45 tahun (26,54%) dan terkecil adalah usia ≥ 60 tahun (10,97%). Populasi perempuan lebih besar dibandingkan laki-laki (53,36% vs 46,64%). Kemudian hanya 6.41% orang bekerja sebagai petugas kesehatan. Jumlah orang yang tidak divaksin lebih banyak dibandingkan orang yang divaksin (52,58% vs. 47,42%). Dibandingkan dengan pasien COVID-19 yang tidak divaksinasi, pasien yang divaksin mengalami penurunan risiko dirawat sebesar 45% (periode 1), 43,3% (periode 2), dan 24% (periode 3). Kemudian pasien COVID-19 yang divaksinasi mengalami penurunan risiko mortalitas sebesar 35% (periode 1), 90% (periode 2), dan 33% (periode 3). Sehingga peneliti menyimpulkan bahwa vaksinasi COVID-19 menurunkan risiko dirawat di RS dan mortalitas pasien COVID-19 pada ketiga periode sakit.

---

COVID-19 has infected and caused the deaths of millions of people in the world. And vaccination is expected to reduce the incidence, mortality, and severity of the disease. The objective of this research is to discover the effects of COVID-19 vaccination against severe disease and death of COVID-19. This was a retrospective cohort research that utilized data from the COVID-19 NAR database and the Depok City Health Department KPCPEN Dashboard from Mei 8, 2020 to February 20, 2023, and was analysed using logistic regression. We discovered that the largest age group were patients between ages 31-45 years (26.54%) and the smallest was ≥ 60 years (10.97%). There were more female patients than men (53.36% vs. 46.64%). Only 6.41% of patients were healthcare workers, and more patients were unvaccinated than vaccinated (52.58% vs. 47.42%). Compared to the unvaccinated patients, the vaccinated patients experienced a risk reduction of 45% in period 1, 43.3% in period 2, and 24% in period 3. Vaccinated patients also experienced a risk reduction for mortality of 35% in period 1, 90% in period 2, and 33% in period 3. Therefore, we conclude that COVID-19 vaccination reduces the hospitalization and mortality risks for COVID-19 patients in all 3 periods."

"Latar belakang dilakukannya penelitian ini adalah terdapatnya kendala pada proses internal manajemen vaksinasi COVID-19 drive thru Rumah Sakit Universitas Indinesia (RSUI). Dimana Vaksinasi tersebut merupakan bagian dari program penanggulangan COVID-19 yang menyangkut kepentingan masyarakat umum terutama pada aspek kesehatan. Tujuan dilakukan penelitaian ini adalah untuk menganalisis tentang kualitas pada proses internal pelayanan vaksinasi COVID-19 drive thru di Rumah Sakit Universitas Indinesia (RSUI). Pendekatan penelitian yang digunakan ialah postpositivsm dengan dengan desain deskriptif melalui teori internal quality (INTQUAL). Metode penelitian yang digunakan adalah kualitataif, dengan pengumpulan data melalui wawancara mendalam dengan empat infoman inti yang terlibat secara langsung dalam pelayanan selama tiga periode dan studi kepustakaan. Hasil dari penelitian ini menunjukan bahwa kualitas pada proses internal pelayanan vaksinasi COVID-19 drive thru RSUI sudah cukup baik. Hal tersebut diperoleh dari analisis delapan indikator dalam teori INTQUAL yang meliputi tools, policies and procedures, teamwork, management support, goal alignment, effective training, communication, dan reward and recognition.

---

The background of this research is the constraints on the internal process of management drive thru COVID-19 vaccination at the University of Indonesia Hospital (RSUI). The vaccination is a COVID-19 mitigation program that concerns the interests of the general public, especially in health aspects. The purpose of this research is to analyze the quality of the internal process by drive thru COVID-19 vaccination services in the University of Indonesia Hospital (RSUI). The research approach used is postpositivsm with a descriptive design through the theory of internal quality (INTQUAL). The research method used is qualitative, with data collection through in-depth interviews with four core infomen directly involved in the ministry over three periods and literature studies. The results showed that internal quality process of RSUI's internal drive thru COVID-19 vaccination service is quite good. This is obtained from the analysis of eight indicators in INTQUAL theory which include tools, policies and procedures, teamwork, management support, goal alignment, effective training, communication, and reward and recognition"

"Cakupan vaksinasi COVID-19 lansia di Kelurahan Batu Ampar sebesar 61%. Cakupan tersebut menjadikan Kelurahan Batu Ampar termasuk wilayah terendah kedua dalam cakupan vaksinasi di Kecamatan Kramat Jati, Jakarta Timur. Penelitian ini bertujuan untuk mengetahui perilaku vaksinasi COVID-19 pada lansia dan determinannya di wilayah kerja Puskesmas Kelurahan Batu Ampar Jakarta Timur. Penelitian ini menggunakan metode kuantitatif dengan desain cross sectional. Teknik pengolahan sampel menggunakan analisis univariat, bivariat dan multivariat dengan uji regresi logistik ganda. Pengumpulan data melalui pengisian kuesioner yang telah diuji validitas dan reliabilitasnya pada 121 lansia yang berdomisili di wilayah kerja Puskesmas Kelurahan Batu Ampar Jakarta Timur. Hasil penelitian menunjukkan 82,6% lansia telah menerima vaksinasi COVID-19 dengan status dosis pertama sebanyak 5,8%, dosis kedua sebanyak 37% dan booster pertama sebanyak 46,3%. Hasil penelitian juga menunjukkan pengetahuan (p=0,011) dan aksesibilitas jarak (p=0,001) sangat berhubungan dengan perilaku vaksinasi COVID-19 pada lansia. Aksesibilitas jarak merupakan faktor yang dominan berhubungan dengan perilaku vaksinasi COVID-19 pada lansia.

---

The coverage of the elderly COVID-19 vaccination in Batu Ampar Village is 61%. This coverage makes Batu Ampar Village the second lowest area in vaccination coverage in Kramat Jati District, East Jakarta. This study aims to determine the behavior of COVID-19 vaccination in the elderly and its determinants in the work area of the Batu Ampar Village Health Center, East Jakarta. This study uses a quantitative method with a cross sectional design. The sample processing technique used univariate, bivariate and multivariate analysis with multiple logistic regression. Collecting data through filling out questionnaires that have been tested for validity and reliability on 121 elderly who live in the working area of the Puskesmas Batu Ampar, East Jakarta. The results showed that 82.6% of the elderly had received COVID-19 vaccination with 5.8% first dose status, 37% second dose and 46.3% first booster. The results also showed that knowledge (p=0.011) and distance accessibility (p=0.001) were strongly related to the behavior of COVID-19 vaccination in the elderly. Distance accessibility is the dominant factor related to COVID-19 vaccination behavior in the elderly"

"Kepatuhan terhadap protokol kesehatan mengalami penurunan setelah dilaksanakannya vaksinasi COVID-19. Implementasi protokol kesehatan di Kecamatan Ciracas, Jakarta Timur masih berada di bawah standar kepatuhan protokol kesehatan di setiap daerah, sedangkan program vaksinasi sudah dilakukan dari bulan Januari 2021. Tujuan penelitian ini untuk mengetahui faktor-faktor yang berhubungan dengan kepatuhan protokol kesehatan pasca vaksinasi pada masyarakat di Kecamatan Ciracas tahun 2022. Penelitian ini merupakan penelitian kuantitatif dengan desain cross sectional menggunakan data primer. Sampel penelitian ini berjumlah 178 sampel. Hasil penelitian menunjukkan bahwa responden sudah patuh dengan nilai rata-rata 80,18 dari skala 100. Uji statistik menunjukkan bahwa jenis kelamin (p value = 0,001), pengetahuan (p value = 0,005), persepsi kerentanan (p value = 0,037), persepsi keparahan (p value = 0,037) dan persepsi manfaat (p value = 0,001) berhubungan dengan kepatuhan protokol kesehatan pasca vaksinasi. Hasil penelitian menyarankan untuk memperkuat komunikasi masyarakat, edukasi yang lebih massif kepada tokoh masyarakat, tokoh agama hingga ketua wilayah dengan menjadikan sebagai agen promosi kesehatan, serta memperkuat platform online untuk dijadikan media promosi kesehatan yang sederhana, menarik dan mudah dipahami.

---

Compliance with health protocols has decreased after the COVID-19 vaccination was implemented. The implementation of health protocols in Ciracas District, East Jakarta still below the standard of compliance with health protocols in each region, while the vaccination program has been carried out since January 2021. The purpose of this study was to determine the factors associated with post-vaccination health protocol compliance in the community in Ciracas District in 2022. This research is a quantitative study with a cross sectional design using primary data. The sample of this study amounted to 178 samples. The results showed that the respondents were obedient with an average value of 80.18 from a scale of 100. Statistical tests showed that gender (p value = 0.001), knowledge (p value = 0.005), perception of vulnerability (p value = 0.037), perception severity (p value = 0.037) and perceived benefit (p value = 0.001) were associated with post-vaccination health protocol compliance. The results of the study suggest strengthening community communication, more massive education to community leaders, religious leaders to regional leaders by making them as health promotion agents, as well as strengthening online platforms to be simple, attractive and easy to understand health promotion media."

"COVID-19 merupakan penyakit menular yang disebabkan oleh SARS-CoV-2 dan ditetapkan sebagai pandemi global pada 11 Maret 2020 oleh WHO. Pemerintah Republik Indonesia mulai melaksanakan program vaksinasi booster untuk meningkatkan durabilitas sistem imun, khususnya pada tenaga kesehatan untuk memicu reaksi imunogenitas pada tubuh melalui produksi antibodi netralisasi (NAb). Namun, NAb memiliki durabilitas tertentu dan mungkin akan mengalami penurunan yang turut dipengaruhi oleh adanya SARS-CoV-2 varian baru yang muncul seperti varian Delta dan Omicron. Tujuan dari penelitian ini adalah mengevaluasi antibodi netralisasi yang dihasilkan oleh tenaga kesehatan di Jakarta sebelum dan setelah 12 bulan vaksinasi booster COVID-19, mengevaluasi antibodi netralisasi setelah 12 bulan vaksinasi booster COVID-19 terhadap 4 varian SARS-CoV-2 berupa varian wild type, Delta, Omicron (B.1.1.529), dan Omicron (BA.2), dan mengevaluasi antibodi netralisasi pada partisipan yang mengalami breakthrough infection dengan partisipan yang tidak mengalami breakthrough setelah 12 bulan vaksinasi booster COVID-19. Metode yang digunakan dalam penelitian ini adalah uji Surrogate Virus Neutralization Test (sVNT) yang sesuai untuk digunakan dalam mendeteksi antibodi netralisasi karena memiliki hasil yang baik dengan waktu deteksi singkat. Hasil penelitian yang diperoleh adalah terdapat kenaikan antibodi netralisasi yang signifikan pada saat 12 bulan pascavaksinasi booster dibandingkan dengan saat pravaksinasi booster. Selain itu, terdapat perbedaan kadar antibodi netralisasi antara keempat varian dengan penurunan antibodi netralisasi yang cukup signifikan sekitar 10—20% pada varian Omicron (B.1.1.529 dan BA.2). Tidak terdapat perbedaan antibodi netralisasi yang signifikan pada partisipan yang mengalami breakthrough infection dengan partisipan yang tidak mengalami breakthrough infection, namun, seluruh partisipan breakthrough infection memiliki tingkat keparahan COVID-19 kategori ringan. Kesimpulan penelitian ini adalah vaksinasi booster pertama pada partisipan menunjukkan durabilitas imun pada bulan ke-12 pascavaksinasi booster pertama yang masih tergolong baik dan kemungkinan berpengaruh terhadap rendahnya tingkat keparahan gejala COVID-19 pada partisipan yang mengalami breakthrough infection. Varian baru SARS-CoV-2 seperti Omicron (B.1.1.529 dan BA.2) menyebabkan penurunan respons kekebalan tubuh sehingga perlu dilaksanakan vaksinasi booster lanjutan.

---

COVID-19 is an infectious disease caused by SARS-CoV-2 and was declared as global pandemic on 11 March 2020 by WHO. The Government of the Republic of Indonesia has started implementing a booster vaccination program to increase the durability of the immune system, especially for healthcare workers to trigger an immunogenic reaction in the body through the production of neutralizing antibodies (NAb). However, NAb has a certain durability and may experience a decrease which is also influenced by the emergence of new SARS-CoV-2 variants such as the Delta and Omicron variants. The purpose of this study was to evaluate the neutralization antibodies produced by healthcare workers in Jakarta before and after 12 months of the COVID-19 booster vaccination, to evaluate the neutralization antibodies after 12 months of the COVID-19 booster vaccination against 4 variants of SARS-CoV-2 in the form of wild type variants, Delta, Omicron (B.1.1.529), and Omicron (BA.2), and evaluated neutralizing antibodies in participants who experienced a breakthrough infection with participants who did not experience a breakthrough after 12 months of the COVID-19 booster vaccination. The method used in this study is the Surrogate Virus Neutralization Test (sVNT) which is suitable for detecting neutralizing antibodies because it has good results with a short detection time. The results of the study were that there was a significant increase in neutralizing antibodies 12 months after the booster vaccination compared to the prevaccination booster. In addition, there were differences in neutralizing antibody levels between the four variants with a significant decrease in neutralizing antibodies of around 10—20% in the Omicron variants (B.1.1.529 and BA.2). There was no significant difference in neutralizing antibodies in participants who experienced a breakthrough infection and participants who did not experience a breakthrough infection. However, all breakthrough infection participants had a mild level of COVID-19 severity. The conclusion of this study is that the first booster vaccination in participants shows immune durability at the 12th month after the first booster vaccination which is still relatively good and may have an effect on the lower severity of COVID-19 symptoms in participants who experience a breakthrough infection. New variants of SARS-CoV-2 such as Omicron (B.1.1.529 and BA.2) cause a decrease in the body's immune response so that further booster vaccinations are necessary."

"Penelitian ini menggunakan teori Extended Parallel Process Model (EPPM) mengkaji pemberian pesan dengan pendekatan rasa takut terhadap minat perilaku vaksinasi Covid-19 dalam konteks Indonesia. Penelitian ini mengkaji pengaruh pemberian kampanye ancaman tinggi dengan efikasi tinggi serta kampanye ancaman tinggi dengan efikasi rendah terhadap minat perilaku vaksinasi. Melalui metode eksperimen desain antar kelompok dengan kelompok kontrol yang mendapat perlakuan berbeda kemudian diuji dengan Uji F (ANOVA) satu jalur. Hasil penelitian menunjukkan bahwa kampanye ancaman tinggi dengan efikasi tinggi terbukti memicu minat perilaku vaksinasi Covid-19 pro-aktif yakni signifikan di minat perilaku vaksinasi individu, minat pencarian informasi, minat daftar vaksin dan minat mengajak lingkungan untuk vaksin. Sementara kampanye ancaman tinggi dengan efikasi rendah hanya memicu minat perilaku vaksinasi Covid-19 pasif yaitu signifikan di minat perilaku vaksinasi individu namun, tidak di variabel minat pencarian informasi, minat daftar vaksin dan minat mengajak lingkungan untuk vaksin.

---

Employing Extended Parallel Process Model (EPPM) theory, this papers examined the delivery of vaccination campaign with a fear appeal to the behavioral intention of Covid-19 vaccination in Indonesia context. This study examines the application of high threat and high efficacy campaigns also low threat and low efficacy campaigns on vaccination behavioral intention. Through experimental between-subject post – test only control groups design that received different treatment then tested with the one-way F Test (ANOVA). The results showed that high threat and high efficacy campaigns were proven to trigger pro-active Covid-19 vaccination behavioral intention, which was significant in individual vaccination behavioral intention, information seeking intention, vaccine registration intention and ask colleagues for vaccines intention. While high threat and low efficacy campaigns only trigger passive Covid-19 vaccination behavioral intention, which is significant in individual vaccination behavioral intention, but not in information seeking intention, vaccine registration intention and ask colleagues for vaccines intention."

"Program wajib vaksinasi Covid-19 merupakan salah satu bentuk upaya yang dilakukan oleh Pemerintah Indonesia untuk memutus rantai penyebaran virus Covid-19. Namun, program vaksinasi Covid-19 tersebut mendapatkan berbagai macam respon dari masyarakat, sebagian menyambut dan menerima dengan suka cita, namun sebagian lain menaruh keraguan dan berakhir pada keputusan untuk menolak vaksinasi Covid-19. Perbedaan keputusan tersebut ternyata terjadi tidak hanya pada masyarakat umum, tetapi juga pada tenaga kesehatan. Banyak faktor terlibat di dalam proses pengambilan keputusan tersebut. Dalam penelitian ini ditemukan bahwa terdapat keterlibatan affect dan biopower sebagai faktor yang secara signifikan mendorong tenaga kesehatan dalam memutuskan keputusannya terhadap vaksinasi Covid-19. Penelitian ini merupakan penelitian etnografi yang dilakukan di Puskesmas Kecamatan Asih. Studi pustaka, observasi partisipan, dan wawancara mendalam dilakukan sebagai teknik pengumpulan data dalam penelitian ini.

---

The Covid-19 vaccination program is one of the efforts made by the Government of Indonesia to break the chain of spread of the Covid-19 virus. However, the Covid-19 vaccination program received various responses from the public, some welcomed and accepted it, but others put their doubts and ended up with the decision to refuse the Covid-19 vaccination. These differences in these decisions occur not only in the general public, but also in the health workers. Many factors are involved in the decision-making process. This study found that affect and biopower were involved as factors that significantly encourage the health workers in their decision-making process regarding Covid-19 vaccination. This research is an ethnographic research conducted at Puskesmas Asih Kecamatan Asih. Literature study, participant observation, and in-depth interviews were conducted as data collection techniques in this study."

"Vaksinasi Covid-19 di daerah menimbulkan suatu tantangan dan hambatan tersendiri bagi tenaga kesehatan. Tenaga kesehatan menghadapi tantangan dan hambatan seperti penolakan dari masyarakat, kabar bohong, dan kurangnya dukungan lintas sektoral. Latar tempat riset ini adalah Puskesmas Sukajadi, sebuah Puskesmas pedesaan yang berada di daerah Tapal Kuda Jawa Timur. Penelitian ini dilakukan menggunakan metode etnografi. Peneliti melakukan kegiatan observasi dan wawancara dari Februari 2020 hingga Februari 2021. Peneliti mengerangkai tulisan ini dengan menggunakan konsep resiliensi gelombang ketiga yang melihat individu sebagai bagian dari kelompok dan jejaring kebudayaan. Hasil penelitian ini menunjukkan tenaga kesehatan mengalami kewalahan dan moral distress dalam proses vaksinasi Covid-19. Tenaga kesehatan melakukan beberapa cara untuk menghadapi situasi sulit tersebut dengan menghiraukan emosi negative yang mereka rasakan, koping religius, berkumpul bersama orang yang mereka sayangi seperti suami dan anak, serta menjalankan hobi.

---

Covid-19 vaccination in the regions poses a challenge and obstacle fro health workers. Health works face chellenges and obstacles such as rejection from the sommunity, fake news, and a lack of cross-sectoral support. The setting for this research is the Sukajadi Public Health Center, a rural health center located in the Tapal Kuda area of East Java. This research was conducted usiang ethnographic methods. Researchers carried out observations and interviews from February 2020 to February 2021. Researchers framed this paper by using concept of third wave resiliense, which sees individuals as part of cultural groups and networks. The result of this study indicate that health workers were overwhelmed and morally distressed in the Covid-19 vaccination process. Health works tahe several ways to deal with this difficult situation by being indifferent, coping religiously, hanging out with people they case about such as husbands, and children, and doing hobbies."

"Vaksinasi COVID-19 merupakan salah satu alternatif untuk mencegah penyebaran COVID-19. Provinsi Gorontalo merupakan wilayah dengan cakupan vaksinasi COVID-19 yang rendah pada remaja, sehingga perlu dikaji tingkat pengetahuan, sikap, dan keinginan remaja untuk membantu memaksimalkan program vaksinasi COVID-19 di kalangan remaja. Penelitian ini bertujuan untuk mengidentifikasi hubungan tingkat pengetahuan dan sikap dengan keinginan remaja terhadap vaksinasi COVID-19 di Provinsi Gorontalo. Penelitian ini menggunakan desain cross sectional dan metode convenience sampling digunakan dengan melibatkan 444 remaja di Provinsi Gorontalo. Hasil uji chi-square menunjukkan adanya hubungan yang bermakna antara Usia, masalah keuangan, status kesehatan, status COVID-19, status penyakit kronis, riwayat anggota keluarga atau teman yang pernah terinfeksi COVID-19, didiagnosis penyakit kongenital, status pekerjaan orangtua, sumber informasi tentang vaksin COVID-19, tingkat pengetahuan dan sikap dengan keinginan remaja terhadap vaksinasi COVID-19. Analisis regresi logistik menunjukkan variabel dominan yaitu sikap positif terhadap keinginan remaja untuk vaksin COVID-19, yaitu dengan nilai p = < 0,001 dan aOR = 9,643 (95% CI = 4,850 – 19,171). Secara keseluruhan terdapat hubungan antara tingkat pengetahuan dan sikap dengan keinginan remaja terhadap vaksinasi COVID-19 di Provinsi Gorontalo. Pemerintah perlu membuat kebijakan khusus mengenai vaksin COVID-19 terhadap remaja, guna meningkatkan cakupan vaksinasi COVID-19.

---

Vaccination against COVID-19 is an alternative to prevent the spread of COVID- 19. Gorontalo Province is an area with low COVID-19 vaccination coverage for adolescents, so it is necessary to study the level of knowledge, attitudes, and willingness of adolescents to help maximize the COVID-19 vaccination program among adolescents. This study aims to identify the relationship between the level of knowledge and attitudes with adolescents' willingenss for COVID-19 vaccination in Gorontalo Province. This study used a cross-sectional design and the convenience sampling method involved 444 adolescents in Gorontalo Province. The results of the chi-square test showed that there was a significant relationship between age, financial problems, health status, COVID-19 status, chronic disease status, history of family members or friends who had been infected with COVID- 19, diagnosed with congenital diseases, parents' employment status, sources of information. about the COVID-19 vaccine, the level of knowledge and attitudes of adolescents towards the COVID-19 vaccination. Logistic regression analysis showed that the dominant variable was a positive attitude towards adolescents' willingness for the COVID-19 vaccine, with p value = < 0.001 and aOR = = 9,643 (95% CI = 4,850 – 19,171). Overall, there is a relationship between the level of knowledge and attitudes with the willingness of adolescents towards COVID-19 vaccination in Gorontatol Province. The government needs to make a special policy regarding the COVID-19 vaccine for adolescents, in order to increase the coverage of the COVID-19 vaccination."