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"Coronavirus Disease 2019 adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Covid-19 telah dinyatakan sebagai pandemik sehingga perlu dilakukan upaya penanggulangan termasuk penguatan fungsi laboratorium yang berfungsi melakukan pemeriksaan spesimen, untuk menjamin kesinambungan pemeriksaan screening spesimen Coronavirus Disease 2019. Penelitian ini bertujuan untuk menganalisis implementasi hierarki pengendalian risiko dalam pencegahan penularan Covid-19 pada pekerja di Laboratorium Biomolekular PT X. Penelitian ini menggunakan metode penelitian kualitatif . Pengumpulan data dilakukan melalui data sekunder, wawancara dan observasi. Penelitian dilakukan dari November 2021-Juli 2022. Hasil penelitian menunjukkan proses kerja di PT. X terdiri enam jenis dari pengambilan sampel hingga pelaporan ke pasien. Masing-masing proses memiliki risiko masing-masing dalam pekerjaannya, dimana risiko tertinggi pada petugas pengambilan sampel. Pengetahuan dan perilaku pekerja terhadap hirarki pengendalian risiko dapat dikatakan sangat baik. Perilaku pencegahan Covid-19 yang dilakukan oleh pekerja di PT. X sudah ada upayanya, seperti mereka paham pentingnya bekerja dengan SOP dan menggunakan alat pelindung diri. PT.X telah mengimplementasikan hirarki pengendalian risiko meliputi pengendalian teknis seperti memberi pembatas dan pengaturan ventilasi, pengendalian administrasi seperti pembuatan SOP dan pengaturan shift kerja, dan penggunaan alat pelindung diri seperti masker, baju gown, sarung tangan, dsb. Terkait implementasi pengendalian risiko pada Laboratorium ada dua hal yang belum terpenuhi yaitu tidak adanya pengelolaan limbah padat B3 dan tidak ada manajemen biosecurity secara mandiri. Adapun saran yang dapat direkomendasikan adalah perlu memberikan edukasi, sosialisasi, maupun pelatihan secara berkala terkait manajemen pengendalian risiko dan melakukan upaya pengelolaan limbah B3 sendiri mengacu pada peraturan kementerian kesehatan untuk keamanaan baik para pekerja dan pelanggan yang berkunjung ke PT.X.

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Coronavirus Disease 2019 is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Covid-19 has been declared a pandemic so it is necessary to take countermeasures including strengthening the laboratory function that functions to examine specimens, to ensure the continuity of the 2019 Coronavirus Disease specimen screening examination. This study aims to analyze the implementation of the risk control hierarchy in preventing the transmission of Covid-19 to workers in Biomolecular Laboratory of PT X. This research uses qualitative research methods. Data was collected through secondary data, interviews and observations. The research was conducted from November 2021-July 2022. The results showed that the work process at PT. X consists of six types from sampling to reporting to patients. Each process has its own risks in its work, where the risk is highest for the sampling officer. Knowledge and behavior of workers on the hierarchy of risk control can be said to be very good. Covid-19 prevention behavior carried out by workers at PT. X has made an effort, as they understand the importance of working with SOPs and using personal protective equipment. PT.X has implemented a risk control hierarchy including technical controls such as providing barriers and ventilation settings, administrative controls such as making SOPs and setting work shifts, and the use of personal protective equipment such as masks, gowns, gloves, etc. Regarding the implementation of risk control in the laboratory, there are two things that have not been fulfilled, namely the absence of B3 solid waste management and no independent biosecurity management. The suggestions that can be recommended are that it is necessary to provide education, socialization, and periodic training related to risk control management and make efforts to manage B3 waste itself referring to the regulations of the ministry of health for the safety of both workers and customers who visit PT.X.

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"Latar Belakang: Aktivasi komplemen dapat menyebabkan respon imun berlebihan dan merupakan salah satu faktor yang berpengaruh terhadap morbiditas serta mortalitas pasien COVID-19. Beberapa penghambat aktivasi komplemen saat ini sedang dipelajari untuk menghambat aktivasi sistem komplemen yang berlebihan pada pasien COVID-19. Resiko, keuntungan, waktu pemberian dan bagian dari sistem yang akan ditargetkan perlu dipertimbangkan pada saat akan menggunakan penghambat komplemen, oleh karena itu telaah sistematis ini dibuat untuk mengambil kesimpulan apakah pemberian terapi penghambat sistem komplemen dapat menurunkan mortalitas pasien COVID-19 yang dirawat di Rumah Sakit berdasarkan penelitian-penelitian yang tersedia.Tujuan: Mengetahui efek pemberian terapi penghambat sistem komplemen terhadap mortalitas pasien COVID-19 yang dirawat di Rumah Sakit.Metode: Dengan menggunakan kata kunci spesifik, dilakukan pencarian artikel potensial secara komprehensif pada PubMed, Embase, Cochrane, dan Scopus database dengan pembatasan waktu 2019 sampai dengan sampai 31 Desember 2022. Protokol studi ini telah diregistrasi di PROSPERO (CRD42022306632). Semua penelitian pemberian terapi penghambat komplemen pada pasien COVID-19 dimasukkan. Analisis statistik dilakukan dengan menggunakan perangkat lunak Review Manager 5.4.Hasil: 5 penelitian memenuhi kriteria dan dimasukkan dalam telaah sistematis serta meta-analisis dengan total 739 pasien COVID-19. Hasil analisis Forest plot menunjukan bahwa pemberian terapi penghambat sistem komplemen menurunkan mortalitas sebesar 28% pada pasien COVID-19 yang dirawat di Rumah Sakit (RR 0,72; 95% CI: 0,46 – 1,14, I2 = 61%, P-value = 0.16).Kesimpulan: Pemberian terapi penghambat sistem komplemen secara statistik tidak signifikan menurunkan mortalitas pada pasien COVID-19 yang dirawat di Rumah Sakit

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Background: Complement activation can cause an exaggerated immune response and is one of the factors that influence the morbidity and mortality of COVID-19 patients. Several complement activation inhibitors are currently being studied to inhibit excessive complement activation in COVID-19 patients. The risks, benefits, time of administration and the part of the system to be targeted need to be considered when using complement inhibition, therefore this systematic review was made to conclude whether the administration of complement system inhibition therapy can reduce the mortality of COVID-19 patients who are hospitalized based on available studies.

Objective: To determine the effect of complement system inhibitory therapy on the mortality of hospitalized COVID-19 patients

Methods: Using specific keywords, we comprehensively searched the PubMed, Embase, Cochrane, and Scopus databases for potential articles from 2019 to December 31, 2022. The research protocol was registered with PROSPERO (CRD42022306632). All studies administering complement inhibitory therapy to COVID-19 patients were processed. Statistical analysis was performed using Review Manager 5.4 software.

Result: 5 studies met the criteria and were included in a systematic review and meta-analysis of a total of 739 COVID-19 patients. The results of the Forest plot analysis showed that administration of complement system inhibitor therapy reduced mortality by 28% in hospitalized COVID-19 patients (RR 0.72; 95% CI: 0.46 – 1.14, I2 = 61%, P -value = 0.16).

Conclusion: Providing complement system inhibitor therapy did not statistically significantly reduce mortality in hospitalized COVID-19 patients"

"Pandemi Coronavirus Disease 2019 (COVID-19) merupakan pandemi disebabkan oleh virus SARS-CoV-2. Indonesia diketahui sebagai salah satu negara dengan tingkat infeksi COVID-19 paling tinggi di dunia. Deteksi cepat secara Real Time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) merupakan salah satu langkah yang diperlukan untuk menekan laju penyebaran COVID-19. Kit deteksi BioCore 2019-nCoV Real Time PCR Kit adalah salah satu kit dignosis COVID-19 produksi BioCore. Ltd., Korea Selatan. Kit diagnosis BioCore telah beredar di Indonesia dan perlu diuji keakuratan diagnosis yang dihasilkan untuk menghindari hasil negatif palsu. Pengujian dilakukan menggunakan protokol Penjaminan Mutu Eksternal (PME) Kementerian Kesehatan Indonesia dengan melibatkan 30 sampel uji dan membandingkan hasil uji terhadap kit gold standard CDC dengan gen target N1, N2, dan HRP. Alur kerja penelitian dimulai dari proses pengambilan sampel, ekstraksi RNA, persiapan mastermix, adisi template RNA, dan amplifikasi template dengan metode rRT-PCR. Hasil penelitian menunjukkan adanya amplifikasi pada kontrol yang digunakan, sehingga proses diagnosis dapat dilakukan. Nilai Ct IC kit Biocore dan IC CDC menunjukkan perbedaan signifikan (P 0,05; CI=95%). Gen target SARS-CoV-2 tidak terdeteksi pada kit Biocore dengan nilai Ct>35, serta didapatkan nilai sensitivitas dan spesifisitas analitik kit Biocore berturut-turut sebesar 75% dan 100%. Hasil uji Kit Biocore terhadap pasien terinfeksi COVID-19 di Indonesia tidak memenuhi standar kit diagnosis yang ditetapkan oleh WHO, yaitu memiliki sensitivitas analitik sebesar 95%. Peninjauan ulang primer pada kit Biocore perlu dilakukan untuk memperbaiki mutu kit dalam deteksi awal virus SARS-CoV-2 di Indonesia.

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The Coronavirus Disease 2019 (COVID-19) pandemic is a pandemic caused by the SARS-CoV-2 virus. Indonesia is known as one of the countries with the highest COVID-19 infection rate in the world. Real Time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) detection is one of the steps needed to accelerate the spread of COVID-19. The BioCore 2019-nCoV Real Time PCR Kit is one of the COVID-19 diagnosis kits produced by BioCore. Ltd., South Korea. The BioCore diagnostic kit has been circulating in Indonesia and needs to be tested for the accuracy of the resulting diagnosis to avoid false negative results. The test was carried out using the External Quality Assurance (PME) protocol of the Indonesian Ministry of Health involving 30 test samples and test results against the CDC gold standard kit with target genes N1, N2, and HRP. The research workflow starts from the sampling process, RNA extraction, mastermix preparation, RNA template addition, and template amplification using the rRT-PCR method. The results showed that there was amplification of the controls used, so that the diagnosis process could be carried out. The Ct values ​​of the Biocore IC kit and the CDC IC showed a significant difference (P 0.05; CI=95%). The SARS-CoV-2 target gene was not detected in the Biocore kit with a Ct value>35, ​​and the sensitivity and analytical specificity of the Biocore kit were 75% and 100%, respectively. The results of the Biocore Kit test on patients infected with COVID-19 in Indonesia do not meet the diagnostic kit standard set by WHO, which has an analytical sensitivity of 95%. Primary review on the Biocore kit needs to be done to improve the quality of the kit in early detection of the SARS-CoV-2 virus in Indonesia."

"Perkantoran merupakan salah satu tempat yang berisiko terjadinya penularan COVID-19. Beberapa kasus COVID-19 di DKI Jakarta didominasi dari klaster perkantoran. Untuk mengatasi hal tersebut, penerapan perilaku pencegahan yang baik menjadi kunci utama dalam memutus rantai penyebaran virus. Tujuan penelitian ini adalah untuk menganalisis faktor determinan perilaku pencegahan penularan COVID-19 pada pekerja perkantoran di DKI Jakarta. Penelitian ini merupakan penelitian kuantitatif dengan desain cross sectional. Pengambilan data dilakukan secara daring menggunakan kuesioner. Sebanyak 152 pekerja perkantoran di Jakarta berpartisipasi dalam penelitian ini. Hasil penelitian menunjukkan bahwa perilaku pencegahan responden terhadap COVID-19 sudah cukup baik. Sebesar 61,2% Responden berperilaku baik, dan 38,8% berperilaku kurang baik. Uji statistik menunjukkan bahwa persepsi risiko (p= 0.013), persepsi hambatan (p= 0.001), sarana prasarana (0.002), dan dukungan manajemen (p= 0.001) berhubungan dengan perilaku pencegahan COVID-19. Maka dari itu diperlukan edukasi efektif, penyediaan sarana prasarana yang memadai, serta dukungan manajemen yang mendukung untuk meningkatkan perilaku pekerja dalam mencegah COVID-19.

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Office is one of the places at risk of transmission of COVID-19. Several cases of COVID-19 in DKI Jakarta are dominated by office clusters. To overcome this, the implementation of good preventive behavior is the main key in breaking the chain of virus spread. The study aims to analyze the determinants of behavior to prevent transmission of COVID-19 in office workers in DKI Jakarta. This research is a quantitative research with a cross sectional design. Data was collected online using questionnaire. A total of 152 office workers in Jakarta participated in this study. The results showed that the respondent's preventive behavior against COVID-19 is quite good. 61.2% of respondents had good behavior, and 38.8% had poor behavior. Statistical tests showed that perceived risk (p= 0.013), perceived barriers (p= 0.001), availability of facilities (0.002), and management support (p= 0.001) were associated with COVID-19 prevention behavior. Therefore, effective education is needed, the provision of adequate infrastructure, and supportive management support to improve worker behavior in preventing COVID-19."

"Latar belakang. Coronavirus disease-2019 (COVID-19) memiliki spektrum penyakit yang sangat luas dari gejala ringan sampai berat, hingga kematian. Reaksi inflamasi berat akibat dari COVID-19 ini menimbulkan gangguan hemostasis yang disebut dengan COVID-19 associated coagulopathy. Penelitian ini bertujuan untuk menilai profil koagulasi pada pasien dalam pemantauan (PDP) ataupun terkonfirmasi COVID-19 serta hubungannya terhadap mortalitas 30-hari pasien.Metode. Studi ini merupakan studi kohort retrospektif di RS Cipto Mangunkusumo (RSCM) selama Maret 2020 hingga Juni 2020. Sebanyak 106 subjek yang sesuai kriteria inklusi dianalisis dari data rekam medis. Dilakukan pengambilan data berupa data demografik, klinis atau hemodinamik pasien, profil koagulasi saat subjek ditentukan sebagai PDP atau terkonfirmasi COVID-19, pemberian terapi tromboprofilaksis heparin, dan status mortalitas 30 hari setelah admisi. Perhitungan statistik dilakukan dengan menggunakan Statistical Package of Social Science (SPSS) versi 24.0. Profil koagulasi subjek penyintas 30 hari dibandingkan dengan subjek yang mengalami mortalitas. Variabel profil koagulasi yang bermakna kemudian dianalisis dengan analisis bivariat dan regresi logistik multivariat.Hasil. Pada kelompok yang mengalami mortalitas 30-hari ditemukan adanya peningkatan jumlah leukosit (p: 0,022), penurunan kadar trombosit (p: 0,016), dan waktu protrombin (PT) dan waktu activated partial thromboplastin time (APTT) yang lebih panjang (p: 0,002 dan p: 0,018) dibandingkan pada kelompok penyintas 30-hari. Tidak ditemukan perbedaan fibrinogen dan d-Dimer yang bermakna secara statistik. PT merupakan suatu profil koagulasi tunggal yang dapat digunakan sebagai prediktor mortalitas 30-hari dengan odds ratio (95% CI) sebesar 1,407 (1,072 – 1,846), nilai p: 0,014.Simpulan. Terdapat hubungan antara faktor koagulasi pasien COVID-19 dengan mortalitas 30 hari di RSCM, khususnya PT yang dapat digunakan sebagai prediktor mortalitas 30-hari.

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.Background. Coronavirus disease-2019 (COVID-19) has a very broad spectrum of disease from mild to severe symptoms, to death. The severe inflammatory reaction as a result of COVID-19 infection causes a hemostasis disorder called COVID-19 associated coagulopathy. This study aims to assess the coagulation profile of patients under monitoring (PDP) or confirmed COVID-19 and its relationship with 30-day mortality.

Method. This retrospective cohort study was conducted at RS Cipto Mangunkusumo (RSCM) from March 2020 to June 2020. A total of 106 subjects who met the inclusion criteria were analyzed from medical record data. Data were collected in the form of patient demographic, clinical or hemodynamic data, coagulation profile when the subject was determined as PDP or confirmed as COVID-19, administration of heparin thromboprophylaxis therapy, and mortality status 30 days after admission. Statistical calculations were performed using the Statistical Package of Social Science (SPSS) version 24.0. We compared the coagulation profiles of the survivor group in contrast to the non-survivor group. Significant coagulation profile variables were analyzed using bivariate analysis and multivariate logistic regression.

Results. There was elevated number of leukocytes (p: 0.022), reduced platelet levels (p: 0.016), and longer prothrombin time (PT) as well as activated partial thromboplastin time (APTT) (p: 0.002 and p: 0.018, consecutively) in non-survivor group. There were no statistical differences in fibrinogen and d-Dimer levels in both groups. Additionally, PT is a single coagulation profile which predicted 30-day mortality with an odds ratio (95% CI) of 1.407 (1.072 - 1.846), and p value: 0.014.

Conclusion. This present study shows abnormal coagulation results are associated with 30-day mortality in COVID-19 patients at RSCM. Prolonged PT was an independent predictor for 30-day mortality in COVID-19 patients"

"Skrining penyakit Coronavirus Disease 2019 (Covid-19) pada petugas kesehatan dan non kesehatan rumah sakit merupakan salah satu upaya mencegah penularan Covid-19 di rumah sakit. Siloam Hospitals Group menerapkan tiga komponen skrining Covid-19 pada petugas, yaitu pengkajian gejala klinis, penemuan kontak erat, serta pemeriksaan antibodi Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) secara berkala. Temuan positif pada minimal satu komponen skrining Covid-19 akan ditindaklanjuti dengan pemeriksaan reverse transcription polymerase chain reaction (RT PCR). Meskipun demikian, keterlambatan penemuan kasus konfirmasi Covid-19 pada petugas di tahun 2020 menuntut penilaian terhadap kinerja skrining Covid-19 yang berjalan saat itu. Penelitian ini mengevaluasi kinerja skrining Covid-19 pada petugas di Siloam Hospitals Group pada tahun 2020 melalui analisis kuantitatif hubungan antara masing-masing komponen skrining Covid-19 dengan luaran hasil RT PCR, dilanjutkan dengan analisis kualitatif berdasarkan aspek evaluasi kinerja skrining menurut Wilson dan Jungner (1968). Desain kuantitatif penelitian ini berjenis kasus kontrol dengan memanfaatkan telaah data secara retrospektif. Data kualitatif penelitian ini diperoleh melalui wawancara mendalam terhadap tiga kriteria informan dan telaah dokumen. Penelitian ini menemukan hubungan signifikan antara gejala klinis khas Covid-19 dan antibodi SARS-CoV-2 dengan luaran hasil RT PCR (p < 0,05), namun tidak terdapat hubungan signifikan antara riwayat kontak erat dengan luaran hasil RT PCR (p > 0,05). Gejala klinis merupakan komponen skrining Covid-19 yang menunjukkan kinerja paling baik dalam memperkirakan luaran hasil RT PCR pada kasus Covid-19 bergejala, namun untuk menangkap kasus Covid-19 presimptomatik dan asimptomatik, penemuan kontak erat seharusnya menjadi komponen skrining yang lebih unggul. Kejadian under reporting dan over reporting dalam penemuan kontak erat menyebabkan kasus konfirmasi Covid-19 terlewat untuk didiagnosis dan kasus non kontak erat terlaporkan sebagai kontak erat dengan mayoritas hasil RT PCR negatif. Uji antibodi SARS-CoV-2 memiliki kinerja yang paling buruk karena memberikan yield yang rendah dalam penemuan kasus dan pengambilan keputusan klinis. Penelitian ini menyimpulkan bahwa pengkajian gejala klinis masih direkomendasikan sebagai komponen skrining Covid-19 yang memiliki kinerja baik. Penemuan kontak erat juga masih direkomendasikan sebagai komponen skrining Covid-19 meskipun kinerjanya memerlukan perbaikan. Sebaliknya, pemeriksaan antibodi SARS-CoV-2 berkala tidak lagi direkomendasikan sebagai komponen skrining Covid-19 karena menunjukkan kinerja yang paling buruk. Pemeriksaan berkala antigen SARS-CoV-2 atau pemeriksaan Nucleic Acid Amplification Test (NAAT) lainnya lebih direkomendasikan jika sudah tersedia.

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The Coronavirus Disease 2019 (Covid-19) screening on healthcare and non-healthcare workers is one of the means to prevent Covid-19 transmission within hospitals. Siloam Hospitals Group implements three components for Covid-19 screening on hospitals’ workers which consists of clinical symptoms assessment, contact finding, and serial Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody testing. Positive finding on at least one of Covid-19 screening components will be followed up by reverse transcription polymerase chain reaction (RT PCR) testing. However, delay in Covid-19 confirmed case findings in hospitals’ workers in 2020 period requires assessment regarding Covid-19 screening performance implemented at the time. This study evaluates Covid-19 screening performance in Siloam Hospitals Group’s workers in 2020 through quantitative analysis of correlation between each of the Covid-19 screening components and RT PCR result, followed by qualitative analysis based on Wilson and Jungner’s (1968) principles of screening performance evaluation. The quantitative approach uses case control study design which collects quantitative data retrospectively. Qualitative data is acquired through in-depth interview with informants from three different criteria and through document study. This study finds significant correlation between Covid-19 clinical symptoms and RT PCR result as well as between SARS-CoV-2 antibody result and RT PCR result (p < 0,05), although no significant correlation is found between contact history and RT PCR result (p > 0,05). Clinical symptom is Covid-19 screening component which shows high performance in predicting RT PCR result for Covid-19 symptomatic cases. However, for Covid-19 presymptomatic and asymptomatic caeas, contact tracing should be placed as superior Covid-19 screening component. Under-reporting and over-reporting found in contact tracing implementation cause misdiagnosis of Covid-19 confirmed cases, while non-eligible contacts are reported as eligible contacts with predominant negative RT PCR results on follow up. SARS-CoV-2 antibody testing shows the lowest performance due to its low yield in case finding and clinical decision making. This study concludes that clinical symptoms assessment is still recommended as Covid-19 screening component with high performance. Contact tracing is also recommended to be used as Covid-19 screening component with performance improvement. In contrast, SARS-CoV-2 antibody testing is no longer recommended as Covid-19 screening component due to its low performance. Antigen SARS-CoV-2 or other Nucleic Acid Amplification Test (NAAT) serial testing is more recommended, if available."

"Pandemi Coronavirus disease 19 (Covid-19) berdampak pada komitmen perawat dalam memberikan asuhan keperawatan dan mempengaruhi kualitas asuhan, kepuasan kerja perawat, dan pencapaian tujuan pelayanan keperawatan. Penelitian ini bertujuan mengidentifikasi determinan komitmen perawat dalam memberikan asuhan keperawatan di era pandemi Covid-19. Desain penelitian yang menggunakan pendekatan cross sectional ini melibatkan 221 perawat pelaksana dan ketua tim di dua rumah sakit umum wilayah Kalimantan Barat. Pengambilan sampel dilakukan dengan teknik simple random sampling. Variabel determinan diukur menggunakan kuesioner dalam bentuk google form yang dikumpulkan secara online. Data dianalisis menggunakan regresi linier berganda. Hasil penelitian mendapatkan determinan komitmen perawat dalam memberikan asuhan keperawatan di masa pandemi Covid-19 adalah kecerdasan emosional (p=0,001) dan dukungan atasan ) p=0,009), yaitu setiap penambahan satu poin kecerdasan emosional dan dukungan atasan akan meningkatkan komitmen perawat dalam memberikan asuhan keperawatan sebesar 0,239 kali dan 0,125 kali. Faktor usia, lama kerja, jenis kelamin, tingkat pendidikan, status pernikahan, dan ruangan unit kerja tidak berhubungan dengan komitmen perawat (p> 0,05). Faktor yang paling berhubungan dengan komitmen perawat dalam memberikan asuhan keperawatan adalah kecerdasan emosional. Dari penelitian ini juga didapatkan kemampuan perawat menilai emosi orang lain dan keinginan perawat bertahan pada profesinya merupakan aspek kecerdasan emosional dan komitmen perawat yang masih perlu ditingkatkan. Hasil penelitian ini dapat digunakan sebagai dasar untuk mengembangkan kompetensi kecerdasan emosional perawat dan membuat strategi dukungan atasan untuk meningkatkan komitmen perawat dalam memberikan asuhan keperawatan.

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The Coronavirus disease 19 (Covid-19) pandemic has an impact on the commitment of nurses in giving nursing care and affects the quality of care, nurse job satisfaction, and the achievement of nursing service goals. This study aims to identify the determinants of nurses' commitment in giving nursing care in the era of the Covid 19 pandemic. The research design using a cross sectional approach involved 221 nurses and team leaders at two public hospitals in West Borneo. Sampling was done by simple random sampling technique. The determinant variable was measured using a questionnaire in the form of a google form which was collected online. Data were analyzed using multiple linear regression. The results showed that the determinants of nurses' commitment in giving nursing care during the Covid-19 pandemic were emotional intelligence (p=0.001) and supervisor support (p=0.009), that is, each addition of one point of emotional intelligence and support from supervisor will increase the commitment of nurses in giving nursing care by 0.239 times and 0.125 times. Factors of age, length of work, gender, education level, marital status, and work unit room were not related to nurse commitment (p> 0.05). The factor that is most closely related to the commitment of nurses in giving nursing care is emotional intelligence. From this study, it was also found that the nurse's ability to assess the emotions of others and the nurses's desire to stay in her profession are aspects of emotional intelligence and nurse commitment that still need to be improved. The results of this study can be used as a basis for developing nurses' emotional intelligence competencies and making supervisor support strategies to increase nurses' commitment in giving nursing care."

"Coronavirus Disease 2019 (disingkat COVID-19) ditetapkan sebagai pandemik oleh Organisasi Kesehatan Dunia (WHO) pada 11 Maret 2020. Pemberitaan tentang pandemik pun menjadi luar biasa banyaknya. Media massa sebagai pemancar informasi yang dapat melewati batas waktu dan geografi sebenarnya memegang peranan penting di masa pandemik COVID-19 ini, yakni untuk memberikan informasi, instruksi dan motivasi perilaku perlindungan diri yang sesuai; menginformasikan perkembangan situasi; membangun kepercayaan pada pejabat/pemerintah; dan menghilangkan rumor. Di sisi lain, media juga memiliki agenda tersendiri dan cara membingkai isu yang sesuai dengan agendanya, yang bisa jadi berlawanan dengan tujuan komunikasi risiko. Salah satu media di Indonesia yang aktif memberitakan situasi terkini terkait pandemik COVID-19, juga aktif melaksanakan fungsi kontrol sosialnya dan lantang menyuarakan kritik adalah majalah Tempo. Oleh karena itu, tujuan penelitian ini adalah menggambarkan isi publikasi majalah Tempo mengenai pandemik COVID-19 periode Maret-Mei 2020 melalui metode analisis isi. Hasil penelitian ini menunjukkan bahwa hanya sebagian kecil saja (rentang 4,8%-22,9%) publikasi mengenai pandemik COVID-19 pada majalah Tempo periode Maret-Mei 2020 yang mengandung unsur komunikasi risiko. Aspek data epidemiologi dan sifat alamiah penyakit hanya mendominasi publikasi pada edisi ke satu bulan Marei 2020, namun terus menurun pada edisi-edisi selanjutnya. Framing Peran Pemerintah juga mendominasi publikasi mengenai pandemik COVID-19 pada publikasi majalah Tempo periode Maret-Mei 2020 yakni dengan persentase 93,9 %, disusul Peran Sosial sebesar 73,8 % dan Dampak Pandemik sebesar 34,3 %. Konsistensi majalah Tempo dalam menjalankan peran sosialnya sebagai “anjing penjaga” yang kritis pada pemerintah kali ini berbenturan dengan anjuran WHO mengenai peran penting media di masa pandemik. Meski proporsi penggunaan framing Peran Pemerintah mulai turun pada bulan Mei dan disusul dengan kenaikan proporsi penggunaan framing Peran Sosial, namun kesan negatif yang terus dipublikasi Tempo menggagalkan salah satu tujuan penting komunikasi di masa pandemik: membangun kepercayaan pada pemerintah. Padahal berdasarkan krisis kesehatan masyarakat di masa lampau yang dipaparkan dalam berbagai penelitian, komunikasi yang tidak tepat yang memicu hilangnya kepercayaan masyarakat pada kemampuan pemerintah untuk mengelola krisis, mengakibatkan hasil tidak terduga dan sangat tidak diinginkan dalam penanganan pandemik terutama terhadap populasi rentan.

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Coronavirus Disease 2019 (abbreviated as COVID-19) was declared as a pandemic by the World Health Organization (WHO) on March 11th, 2020. The news about the pandemic thus become overwhelming. The mass media as a transmitter of information that can cross time and geographic boundaries supposedly play an important role in the pandemic, namely to provide information and motivation to the appropriate self-protecting behavior; update risk information; build trust in officials/government; and dispel rumors. On the other hand, the media also have individual agendas and ways of framing issues that fit the agenda, which may go against the objectives of risk communication. One of the media in Indonesia that actively reports on the current situation related to the COVID-19 pandemic, and also active in carrying out its social control function and voices criticism is Tempo magazine. Therefore, the aim of this study is to describe the contents of the Tempo magazine regarding the COVID-19 pandemic for the period March-May 2020 through content analysis. The results of this study indicate that only a small proportion (ranging from 4.8% to 22.9%) of the publications regarding COVID-19 in Tempo magazine in March-May 2020 which contains elements of risk communication. The aspects of epidemiological data and the nature of the disease only dominate the publication in the initial edition of the study, in the first edition of Maret 2020 tp be precise, but continue to decline in the subsequent editions. The ‘Government's Role’ frames (with the proportion of 93.9%) also dominates the publication regarding COVID-19 in Tempo magazine in March-May 2020, followed by ‘Social’s Roles’ by 73.8% and the ‘Impact of the Pandemic’ by 34.3%. Tempo's consistency in carrying out its social role as a critical "guard dog" for the government, collided with WHO's recommendation regarding the important role of the media during the pandemic. Although the use of the ‘Government’s Role’ frames began to decline in May and was followed by the widespread use of the ‘Social’s Role’ frames, the negative impression that was published by Tempo thwarted one of the important goals of communication during the pandemic: building trust in the government. This is very unfortunate, because based on past public health crises described in various studies, inappropriate communication has led to a loss of public trust in the government's ability to manage the crisis, resulting in unexpected and highly undesirable outcomes in handling the pandemics, especially for vulnerable populations."

"Coronavirus Disease 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS- CoV-2). SARS-CoV-2 merupakan coronavirus jenis baru yang belum pernah diidentifikasi sebelumnya pada manusia. Dampak dari penyakit ini adalah menimbulkan pandemik dengan angka kematian yang sangat tinggi diseluruh dunia. Tujuan umum penelitian ini adalah untuk mengetahui hubungan penderita dengan komorbid hipertensi dengan kejadian kematian akibat Covid-19 di Kota Tangerang Selatan tahun 2020-2021. Desain penelitian yang digunakan desain penelitiaan adalah case control dengan pendekatan kuantitatif. Penelitian ini menggunakan data NAR Kota Tangerang Selatan dan cacatan khusus surveilan pada kasus kematian akibat Covid-19 di Kota Tangerang Selatan berjumlah 13.166 yang terdata sampai tanggal 29 Juni 2021. Data yang dapat dianalisa berjumlah 766 data sampel tersebut didapatkan dengan cara Simple Random Sampling. Teknik analisa data yang dilakukan pada penelitian ini bertahap, meliputi analisa univariat, bivariat, stratifikasi dan analisa multivariat yang diolah menggunakan program statistic. Hasil penelitian menunjukkan bahwa proporsi data dengan kematian akibat Covid-19 pada kelompok kasus dengan komorbid hipertensi sejumlah 189 (49,35%) pasien dan yang tidak komorbid pada kasus kematian yaitu 194 (50,65%), sedangkan yang tidak memiliki komorbid hipertensi dan tidak mengalami kematian akibat Covid-19 sebanyak 345 pasien (90,08%), serta yang memiliki komorbid hipertensi dan tidak mengalami kematian sebanyak 38 pasien (9,92%). Hasil analisis uji logistic regression model akhir menunjukkan hubungan yang signifikan antara komorbid hipertensi dengan kejadian kematian akibat covid-19 dengan OR 7,96 (95% CI: 5,19-12,2; p-value: 0,000) yang artinya bahwa komorbid Hipertensi pada kelompok kasus berisiko 7,96 kali lebih tinggi mengalami kematian akibat covid-19 dibanding kelompok kontrol setelah dikontrol dengan variabel umur, pekerjaan, adanya gejala awal dan penyakit lainnya.

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Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a new type of coronavirus that has never been previously identified in humans. The impact of this disease is causing a pandemic with a very high mortality rate throughout the world. The general purpose of this study was to determine the relationship between patients with comorbid hypertension and the incidence of death due to Covid-19 in South Tangerang City in 2020-2021. The research design used was a case control research design with a quantitative approach. This study uses NAR data from South Tangerang City and special surveillance records on cases of death due to Covid-19 in South Tangerang City totaling 13,166 recorded until June 29, 2021. The data that can be analyzed is 766. The sample data was obtained by means of Simple Random Sampling. Data analysis techniques carried out in this study were carried out in stages, including univariate, bivariate, stratification and multivariate analysis which were processed using statistical programs. The results showed that the proportion of data with deaths due to Covid-19 in the group of cases with comorbid hypertension was 189 (49.35%) patients and those who were not comorbid in cases of death were 194 (50.65%), while those without comorbid hypertension and 345 patients (90.08%) did not die from Covid-19, and 38 patients (9.92%) did not experience comorbid hypertension and did not experience death. The results of the final logistic regression test analysis showed a significant relationship between comorbid hypertension and the incidence of death due to covid-19 with an OR of 7.96 (95% CI: 5.19-12.2; p-value: 0.000) which means that comorbid hypertension the case group had a 7.96 times higher risk of dying from COVID-19 than the control group after controlling for variables of age, occupation, presence of early symptoms and have other diseases."

"Coronavirus Disease (COVID-19) merupakan infeksi sistem pernapasan yang disebabkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Virus ini dapat menyebabkan pneumonia dan berkembang menjadi sindrom distres pernapasan akut/ARDS dan gagal ginjal akut. Pasien terkonfirmasi positif COVID-19 pada laporan ini datang dengan keluhan demam, batuk, sesak, dan terjadi penurunan saturasi oksigen. Hasil chest X-ray menunjukkan infiltrasi bilateral pada kedua lapang paru. Hasil pemeriksaan kimia darah menunjukkan peningkatan kadar kreatinin dan ureum, serta penurunan eGFR. Diagnosis keperawatan yang ditegakkan yakni gangguan pertukaran gas, gangguan ventilasi spontan, gangguan penyapihan ventilator, dan risiko perfusi renal tidak efektif. Intervensi keperawatan yang diberikan kepada pasien yakni pengaturan posisi, terapi oksigen, manajemen ventilasi mekanik, pemantauan respirasi, penyapihan ventilasi mekanik, dan pencegahan syok. Intervensi yang diberikan memberikan hasil yang fluktuatif setiap hari.

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Coronavirus Disease (COVID-19) is an infection of the respiratory system caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus can cause pneumonia and progress to acute respiratory distress syndrome/ARDS and acute kidney injury. The patient reported in this case report arrived Emergency Department with complaints of fever, cough, and respiratory distress. The chest X- ray showed bilateral infiltration in both lung fields. The results of the arterial blood gas showed increased levels of creatinine, urea, and decreased eGFR. The nursing diagnoses made were impaired gas exchange, impaired spontaneous ventilation, impaired ventilator weaning, and the risk of ineffective renal perfusion. Nursing interventions given to patients were positioning, oxygen therapy, mechanical ventilation management, respiration monitoring, mechanical ventilation weaning, and shock prevention. The given intervention gives fluctuating results every day."