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Naomi Esthernita Fauzia Dewanto
"Pertumbuhan mukosa usus manusia belum sempurna saat dilahirkan, karena itu usus bayi sering dikatakan sebagai leaky gut. Probiotik diketahui dapat membantu maturasi saluran cerna. Apakah dalam ASI memang terdapat probiotik ataukah suatu kontaminasi, masih diperdebatkan.
Penelitian ini bertujuan untuk mengetahui apakah probotik ada dalam ASI bila diberikan suplementasi probiotik pada ibu hamil sejak trimester III dan menyusui, efek terhadap probiotik lain dan IL-8 dalam ASI, IFABP urin dan alfa-1-antitripsin (AAT) serta kalprotektin tinja, saat bayi lahir dan usia tiga bulan, dalam rangka menilai integritas mukosa usus.
Dilakukan penelitian uji klinis, paralel dua kelompok dengan randomisasi, samar ganda yang dilakukan di RS Budi Kemuliaan dan klinik-klinik satelitnya sejak Desember 2014 sampai dengan Desember 2015. Jumlah subjek 35 per kelompok. Digunakan probiotik
Bifidobacterium animalis lactis HNO19 karena bukan merupakan resident bacteria.
Lima subjek positif DR10 dalam kolostrum (V0) dan 7 subjek positif saat bayi usia 3 bulan (V3) pada kelompok probiotik. Hasil negatif didapati pada kelompok plasebo. Apusan kulit sekitar payudara negatif pada kedua kelompok. Nilai median IL-8 kelompok probiotik dibanding kelompok plasebo pada V0 dan V3 berturut-turut 2810,1 pg/mL vs. 1516,4 pg/mL (p = 0,327) dan 173,2 pg/mL vs. 132,7 pg/mL (p = 0,211). IFABP V0 dan V3 211,7 ng/mL vs. 842,5 ng/mL (p = 0,243) dan 25,3 ng/mL vs. 25,1 ng/mL (p = 0,466). AAT 136,2 mg/dL vs. 148,1 mg/dL (p = 0,466) dan 24 mg/mL vs. 29,72 mg/mL (p = 0,545). Kalprotektin 746,8 ng/mL vs. 4645,2 ng/mL (p = 0,233) dan 378,6 ng/mL vs. 391,3 ng/mL (p = 0,888).
Probiotik DR10 yang diberikan pada ibu hamil sejak trimester III dapat ditemukan dalam kolostrum dan usia 3 bulan pada kelompok probiotik, dan bukan suatu kontaminasi .Tidak terdapat perbedaan bermakna terhadap probiotik lain, kadar IL-8 dalam ASI, IFABP urin, AAT dan kalprotektin tinja pada kelompok probiotik dibanding dengan kelompok plasebo.

Newborn infants have intestinal hyperpermeability because their gut mucosa is not fully mature yet. It is known that probiotics helps gut maturity. It remains unclear whether probiotics pass through breast milk or whether the positive cultures are the result of contamination. This study aimed to evaluate the effect of probiotic supplementation in pregnant and lactating mothers, with regards to probiotic presence and IL-8
concentration in breast milk, infant urine intestinal fatty acid binding protein (IFABP), as well as fecal ?-1 anti-trypsin (AAT) and calprotectin at birth (V0) and at infant 3
months of age (V3) .
This randomized, controlled trial was double-blind, two parallel groups, probiotic and placebo with 35 subjects in each group. The sudy was done at Budi Kemuliaan Hospital and it’s satellite clinics from December 2014 until December 2015. We used Bifidobacterium
animalis lactis HNO19 (commonly known as DR10) as the supplemental probiotic, as it is not a member of the normal flora.
Probiotik DR10 were found in colostrum at 5 subjects and 7 subjects in V3 breastmilk probiotics group, but none in placebo group. Skin swab of DR10 were negative in both group. Median breast milk IL-8 in probiotic group compare to placebo group at V0 and V3 respectively were 2810.1 pg/mL vs. 1516.4 pg/mL (p = 0.327) and 173.2 pg/mL vs. 132.7 pg/mL (p = 0.211). Infant urine IFABP 211.7 ng/mL vs. 842.5 ng/mL (p = 0.243) and 25.3 ng/mL vs. 25.1 ng/mL (p = 0.466). Infant stool AAT 136.2 mg/dL vs. 148.1 mg/dL (p = 0.466) and 24 mg/mL vs. 29.72 mg/mL (p = 0.545). Stool calprotectin 746.8 ng/mL vs. 4645.2 ng/mL (p = 0.233) and 378.6 ng/mL vs. 391.3 ng/mL (p = 0.888).
Probiotic DR10 were found in colostrum and 3 month-breast milk of women in the probiotic group, but no DR10 in placebo group. However, breast milk IL-8, the presence of other probiotics, and infant gut mucosal integrity were not significantly different between the two groups.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
D-pdf
UI - Disertasi Membership  Universitas Indonesia Library
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Lamtorogung Prayitno
"Bifidobacterium merupakan salah satu anggota mikrobiota dalam saluran pencernaan manusia, terutama pada bayi. Namun demikian, pengaruh breast-fed dan formula-fed pada perkembangan Bifidobacterium dalam mikrobiota usus bayi telah menjadi subyek dari banyak penelitian dan sering memberikan hasil yang bertentangan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh breast-fed eksklusif dan formula-fed terhadap proporsi spesies Bifidobacterium dalam sampel feses bayi. Suatu studi kohort prospektif dari 80 bayi sehat, terbagi menjadi dua kelompok berdasarkan jenis makanan, yaitu kelompok 1 (n = 40) menerima susu formula X yang mengandung Bifidobacterium animalis subsp. lactis HN019 (B. lactis, DR10TM) dan LCPUFA , dan kelompok 2 (n = 40) yang menerima ASI eksklusif. DNA diekstraksi dari sampel feses yang diambil pada saat perekrutan (V0) dan setelah usia 3 bulan (V3). Kuantifikasi dari DR10 dan beberapa spesies Bifidobacterium yang umum terdeteksi dalam feses bayi (B. longum, B. breve, dan B. catenulatum) dilakukan dengan menggunakan 7500 Fast Real-time Quantitative PCR dengan SYBR Green [Applied Biosystems], dengan target daerah internal transcribed spacer (ITS) gen 16S-23S rRNA. Proporsi Bifidobacterium secara bermakna (p = 0,010) meningkat pada kelompok 2, dengan median 37,8 (0,0-94,9) % pada V0 dan 51,6 (15,6-98,4) % pada V3. Namun demikian, tidak terdapat perbedaan proporsi Bifidobacterium diantara kedua kelompok, baik pada V0 (p = 0,551) maupun V3 (p = 0,204). Proporsi DR10 pada V3 secara bermakna lebih tinggi pada kelompok 1 (p = 0,009) dengan rerata 4,88 (11,45) % dibanding kelompok 2 dengan rerata 0,00 (0,00) %. Tidak ada perbedaan bermakna dalam proporsi B. longum, B. breve, dan B. catenulatum antara kelompok 1 dan kelompok 2, baik pada V0 maupun V3. Hasil tersebut menunjukkan bahwa terdapat kemiripan proporsi Bifidobacterium di antara kelompok breast-fed dan formula-fed, khususnya untuk B. longum, B.breve, dan B. catenulatum.

Bifidobacteria is one of the microbiota present in the human gastrointestinal tract, especially in infants. However, the influence of breast-feeding and formula-feeding on the development of Bifidobacteria in the infant gastrointestinal tract microbiota has been the subject of numerous studies that have often yielded conflicting results. The purpose of this study was to determine the influence of either exclusive breast-fed or formula-fed on the proportion of the Bifidobacteria species in infants. A prospective cohort study of 80 full term, healthy infants, formed into two groups based on the type of feeding, group 1 (n = 40) received an infant formula X containing Bifidobacterium animalis subspecies lactis HN019 (B. lactis, DR10TM) and LCPUFA, while group 2 (n = 40) were exclusively breast-feeding. DNA extracted from the faecal samples taken at the time of enrollment (V0) and the 3 months of age (V3). Quantification of the DR10 and the species of Bifidobacteria commonly detected in the faeces of infants (B. longum, B. breve, and B. catenulatum) was carried out using 7500 Fast Real-time Quantitative PCR with SYBR Green [Applied Biosystems], targeting the internal transcribed spacer region of 16S-23S rRNA gene. The proportion of Bifidobacteria were significantly increased in group 2 (p = 0.010), with a median 37.8 (0.0 to 94.9) % at V0 and 51.6 (15.6 to 98.4) % at V3. However, there is no difference in the proportion of Bifidobacteria between the two groups, both in V0 (p = 0.551) and V3 (p = 0.204). The proportion of DR10 in V3 was significantly higher in group 1 (p = 0.009) with a mean 4,88 (11,45) % than in group 2 with a mean 0 (0,00) %. No significant difference in the proportion of B. longum, B. breve, and B. catenulatum between group 1 and group 2, both in V0 and V3. In conclusion, there is a similarity of the proportion of Bifidobacteria in the breast-fed and formula fed infants, especially B. longum, B.breve, and B. catenulatum"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2012
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UI - Tesis Membership  Universitas Indonesia Library
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Kristina Joy Herlambang
"Status gizi pada ibu hamil mempengaruhi komposisi mikrobiota usus ibu yang secara tidak langsung akan mempengaruhi pembentukan mikrobiota usus anak. Penelitian ini adalah suatu studi potong lintang yang mencari korelasi peningkatan berat badan dan lingkar lengan atas dengan jumlah Bifidobacterium dan Lactobacillus pada 52 ibu hamil trimester ketiga. Penelitian dilaksanakan di 10 Puskesmas Kecamatan Jakarta Timur selama bulan Februari?April 2015. Uji korelasi peningkatan BB dengan jumlah Bifidobacterium (r = 0,119, p = 0,4) dan dengan jumlah Lactobacillus (r = -0,009, p = 0,951). Korelasi LLA dengan jumlah Bifidobacterium (r = -0,211, p = 0,134) dan dengan jumlah Lactobacillus (r = - 0,013, p = 0,926). Dengan demikian, penelitian ini belum dapat membuktikan bahwa terdapat adanya korelasi antara peningkatan BB dan LLA dengan jumlah Bifidobacterium dan Lactobacillus pada kehamilan trimester ketiga.

Maternal nutritional status influences maternal gut microbiota composition, which in turn shapes the infant?s gut microbiota composition. Recent studies have shown that gut microbiota regulates obesity by increasing energy harvest from diet and by regulating peripheral metabolism. This cross-sectional study reports the correlation of maternal weight gain and mid-upper arm circumference with Bifidobacterium and Lactobacillus on 52 third-trimester pregnant women. The study was done on February?April 2015 in 10 Primary Health Care Centres in East Jakarta. Correlation of maternal weight gain with Bifidobacterium (r = 0.119, p = 0.4) and with Lactobacillus (r = -0.009, p = 0.951). The correlation of MUAC with Bifidobacterium (r = -0.211, p = 0.134) and Lactobacillus (r = -0.013, p = 0.926). Thus, this study has not proven any correlation between maternal weight gain and MUAC with Bifidobacterium and Lactobacillus count."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tesis Membership  Universitas Indonesia Library
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Marisa
"Bifidobacterium merupakan salah satu mikrobiota yang memberikan manfaat bagi kesehatan manusia termasuk pada kehamilan, dan penting pada proses kolonisasi mikrobiota usus bayi baru lahir. Jumlah Bifidobacterium usus pada dewasa relatif stabil, namun belum diketahui jumlahnya pada ibu hamil trimester ketiga, terutama di Indonesia. Asupan makanan termasuk serat dapat mempengaruhi pertumbuhan Bifidobacterium, termasuk serat. Stimulasi serat terhadap pertumbuhan Bifidobacterium dapat berupa stimulasi langsung sebagai prebiotik, atau secara tidak langsung sebagai substrat yang dapat difermentasi dan menurunkan pH kolon dan meningkatkan enzim intestinal alkaline phospatase (IAP). Dua mekanisme terakhir secara tidak langsung menurunkan jumlah bakteri patogen sehingga jumlah Bifidobacterium meningkat. Penelitian potong lintang di seluruh Puskesmas Kecamatan di Jakarta Timur pada bulan Maret-Juni 2015 dilakukan untuk menilai korelasi asupan serat dengan jumlah Bifidobacterium usus ibu hamil trimester ketiga. Lima puluh dua subjek menyelesaikan prosedur penelitian. Asupan serat dinilai dengan Food Frequency Questionnaire semikuantitatif, dan kuantifikasi Bifidobacterium dengan real time PCR. Nilai asupan serat adalah 18,9 (5,6?43,0) g/hari, dan 92,3% subjek tidak memenuhi AKG. Jumlah Bifidobacterium usus adalah 7,7 (5,12?9,50) log sel/g feses. Tidak terdapat korelasi bermakna (p >0,05) antara asupan serat total, serat larut dan tidak larut, dengan jumlah Bifidobacterium usus (r = 0,223; r = 0,245; r = 0,2).

Bifidobacterium is one of the beneficial microbiota in human health, including in pregnancy and important for first intestinal microbiota colonization in newborn. The number of intestinal Bifidobacterium in adults is relatively stable, but still unknown in the third trimester of pregnancy, especially in Indonesia. Dietary intake is one of the factors influencing the growth of Bifidobacterium, including dietary fiber. Dietary fiber stimulation act directly as a prebiotic, or indirectly as a fermentation substrate that promote the decreasing of colonic pH, and increasing intestinal alkaline phospatase (IAP) enzyme, resulting a decrease of the amount of pathogenic microbiota. A cross-sectional study in all district public health care in the East Jakarta, March until June 2015 was performed to assess the correlation between dietary fiber intake and the amount of intestinal Bifidobacterium in third trimester of pregnancy women. Fifty-two subjects completed the study procedures. Dietary fiber intake was assessed using semiquantitative Food Frequency Questionnaire, and instestinal Bifidobacterium was quantified using real time Polymerase Chain Reaction (rPCR). Dietary fiber intake in this study was 18.9 (5.6?43.0) g/day and 92.3% subjects did not meet the Dietary Reference Intake. The intestinal Bifidobacterium count is 7.7 (5.12?9.50) log cell/g faeces. The results show that there is no significant correlation (p > 0.05) between dietary fiber, dietary soluble fiber, and dietary insoluble fiber intake with the amount of intestinal Bifidobacterium in third trimester of pregnancy (r = 0.223; r = 0.245; r = 0.2)."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T58710
UI - Tesis Membership  Universitas Indonesia Library
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Yannie Mimie Tail
"ABSTRAK
Nama : Yannie Mimie TailProgram Studi : Magister Ilmu Keperawatan Universitas IndonesiaJudul: Hubungan antara lima komponen dukungan suami dengan praktek pemberian ASIIbu yang mendapat dukungan dari pasangannya dapat membuat keputusan untuk menyusui bayinya sejak lahir dan lebih lama. Tujuan penelitian mengidentifikasi hubungan antara lima komponen dukungan suami dengan praktek pemberian ASI. Desain penelitian korelasional, tehnik sampling convenience sampling. Jumlah sampel 93 responden. Hasil penelitian ada hubungan antara pengetahuan suami dan pengambilan keputusan dengan praktek pemberian ASI, dengan nilai p value=0,010 dan p value= 0,003. Tidak ada hubungan antara sikap suami, dukungan praktis dan dukungan emosional suami dengan praktek pemberian ASI, nilai p value= 0,280, p value=0,848, p value=0,379. Yang dominan berhubungan adalah pengambilan keputusan dengan praktek pemberian ASI, dimana nilai p value=0,018. Rekomendasi penelitian adalah pemberian asuhan keperawatan prenatal sampai postnatal, harus mengikutsertakan suami dari ibu hamil sehingga suami memberikan dukungan kepada isterinya untuk memberikan ASI eksklusif.

ABSTRACT
Name YannieMimie TailStudy Program Nursing Faculty Post Graduate ProgramTittle The relationship between the five components husband support thepractice of breastfeeding Mothers who received support from her partner can make the decision to breastfeed from birth and longer. The aim of research identified five components of the relationship between husband support the practice of breastfeeding. Correlational research designs, sampling techniques convinience sampling.Total sample of 93 respondents. The results of the study there was a relationship between husband knowledge and decision making with the practice of breastfeeding, where p value 0.010 and p value 0.003. There is no relationship between husband attitude, practical support and emotional support her husband with the practice of breastfeeding, p value 0.280, p value 0.848, p value 0.379. The dominant one is the decision making related to the practice of breastfeeding, where p value 0.018. Recommendations research is giving prenatal to postnatal nursing care, should include the husband of a pregnant woman so that the husband give to his wife 39 s support exclusivebreastfeeding. "
2017
T47015
UI - Tesis Membership  Universitas Indonesia Library
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Astri Gamanuari Zawati
"ABSTRACT
Penelitian ini bertujuan untuk membuktikan pengaruh antara status gizi ibu postpartum 0 bulan terhadap status gizi bayi 1-4 bulan dan status gizi ibu menyusui selama 4 bulan. Desain yang digunakan adalah cohort prospektif, melibatkan 21 pasang ibu-bayi yang masih menyusui ASI predominan dengan eksposur negatif adalah ibu dengan IMT postpartum 0 bulan kurus dan eksposur positif adalah ibu dengan IMT postpartum 0 bulan normal. Pada Maret-Juni 2014 dengan metode pengambilan sampel adalah purposive sampling. Pengumpulan data dilakukan melalui pengisian kuesioner, wawancara asupan makanan 1x24 jam, pengukuran antropometri (berat badan dan tinggi badan) ibu serta bayi. Uji t-independent menunjukan bahwa terdapat pengaruh bermakna antara status gizi ibu postpartum 0 bulan terhadap status gizi ibu menyusui selama 4 bulan. Uji korelasi menunjukkan terdapat pengaruh bermakna antara berat bayi lahir terhadap status gizi bayi menurut BB/U dan IMT/U dengan tingkat keeratan rendah.

ABSTRACT
The objective of this study is to assess the effect of postpartum 0 month nutrition status to infant nutrition status (1-4 month) and breastfeeding mother during 4 month. Desain of this study is cohort prospective, which conducted on 21 pair mother-infant that still in predominant breastfed period with negative exposure is mother with lower BMI postpartum 0 month and positive exposure is mother with normal BMI postpartum 0 month. On March-June 2014 was used by purposive sampling. Data were collected through the questionnaire, 24 hours food recall, mother and infant anthropometric. Independent t-test showed that there was significant effect between postpartum 0 month nutrition status and breastfeeding mother during 4 month. Correlation test showed that there was significant effect between birth weight and infant nutrition status (weight-age and BMI-age) with low correlation level (r=0,5 and r=0,4)."
2014
S56078
UI - Skripsi Membership  Universitas Indonesia Library
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Nita Amalia
"Gen recA merupakan gen salinan tunggal dan mampu membedakan organisme sampai tingkat subspesies sehingga lebih spesifik dan akurat dalam pendeteksian Bifidobacterium animalis subsp. lactis. Penelitian bertujuan untuk mendapatkan konsentrasi primer yang optimal untuk membuat kurva standar, mengetahui hubungan antara konsentrasi primer dengan nilai Ct pada beberapa sampel DNA dan mengetahui sensitivitas dan spesifisitas primer terhadap DNA target untuk kuantifikasi Bifidobacterium animalis subsp. lactis dengan quantitative Real-time PCR. Isolat DNA berasal dari sampel feses bayi yang diisolasi dengan metode fenol-kloroform. Pasangan primer dirancang berdasarkan sekuens gen recA B. animalis subsp. lactis (NZ_ABOT01000001) menggunakan Primer 3. Beberapa konsentrasi pasangan primer F_HN019_recA dan R_HN019_recA yang digunakan dalam penelitian, antara lain 50/50 nM, 100/100 nM, 300/300 nM, 500/500 nM, dan 1000/1000 nM.
Hasil penelitian menunjukan konsentrasi primer paling optimal untuk membuat kurva standar ialah 1000/1000 nM dengan efisiensi (95,20%) dan R2 (0,998). Konsentrasi primer dan sampel DNA tidak berkorelasi terhadap nilai Ct. Pasangan primer dengan konsentrasi 300/300 nM dapat mengamplifikasi DNA target dengan sensitif sampai dilusi 10-5 , namun spesifik hanya sampai dilusi 10-3. Kesimpulan dari penelitian menunjukkan bahwa primer F_HN019_recA dan R_HN019_recA dengan konsentrasi 50/50 nM -- 1000/1000 nM mampu mengkuantifikasi B. animalis subsp. lactis secara optimal.

The recA gene is a single copy gene and is able to distinguish organisms up to the subspecies levels that are more specific and accurate in the detection of Bifidobacterium animalis subsp. lactis. The research aimed to obtain the optimal primer concentrations to create a standard curve, to determine the correlation between primer concentration with Ct value of several DNA samples and determine primer sensitivity and specificity to the DNA target for quantification of Bifidobacterium animalis subsp. lactis by quantitative Real-time PCR. DNA isolate was derived from infant fecal samples that was isolated using phenolchloroform method. Primer pair was designed based on recA gene sequence B. animalis subsp. lactis (NZ_ABOT01000001) using Primer 3. Several concentrations of primer pair R_HN019_recA and F_HN019_recA that were used in this study include 50/50 nM, 100/100 nM, 300/300 nM, 500/500 nM, and 1000/1000 nM.
The results showed the optimum primer pair concentration to create a standard curve was 1000/1000 nM with efficiency (95.20%) and R2 (0.998). Primer concentrations and DNA samples were not correlated to the Ct value. The primer pair with concentration 300/300 nM was able to amplify DNA target sensitively to dilution 10-5, but specifically only to dilution 10-3. The conclusion of this study showed that primer pair of F_HN019_recA and R_HN019_recA with concentration 50/50 nM – 1000/1000 nM are able to quantify B. animalis subsp. lactis optimally.
"
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2013
S45930
UI - Skripsi Membership  Universitas Indonesia Library
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Manik, Merdina
"Zat besi merupakan mikronutrien esensial yang diperlukan tubuh seperti pertumbuhan sel darah merah dan sel otak Kebutuhan besi meningkat pada masa kehamilan Komposisi mikrobiota dapat berubah selama tahap kehidupan yang dipengaruhi oleh berbagai faktor misalnya besi Penelitian ini merupakan penelitian dengan desain potong lintang yang bertujuan untuk mengetahui korelasi antara asupan besi dan kadar feritin serum dengan jumlah Bifidobacterium pada ibu hamil trimester ketiga Penelitian ini dilakukan di seluruh puskesmas kecamatan di Jakarta Timur dari bulan Maret sampai April 2015 Pengambilan subjek dilakukan dengan cara konsekutif dan didapatkan 52 ibu hamil yang memenuhi kriteria penelitian Data dikumpulkan dengan wawancara meliputi kuesioner data asupan besi heme dan non heme protein serta vitamin C dengan FFQ semikuantitatif Pengukuran antropometri untuk menilai status asupan gizi pemeriksaan laboratorium untuk mengetahui kadar feritin serum dan kadar CRP serta jumlah Bifdobacterium dalam tinja Didapatkan rerata usia 29 1 5 9 tahun nilai median asupan besi 66 7 3 3 144 1 mg hari kadar feritin serum 31 1 3 6 96 1 g L dan jumlah Bifidobacterium usus 7 45 5 1 9 5 log g tinja Tidak didapatkan korelasi yang bermakna asupan besi dengan jumlah Bifidobacterium usus r 0 202 p 0 152 juga tidak didapatkan korelasi bermakna antara kadar feritin serum dengan jumlah Bifidobacterium usus (r=0,116 p=0,411).

Iron is an essensial micronutrient which body needed such as for blood growth cell and brain cell Iron rsquo s requirement increases in pregnancy Microbiota composition can change in cycle of life which be affected by many factors likely iron The aim of this cross sectional study was to find the correlation between iron intake and serum ferritin with Bifidobacterium third trimester of pregnancy Data collection was conducted from March 2015 until April 2015 in all of sub district of public health centre in east Jakarta Subjects were obtained using consecutive sampling method A total of 52 pregnancy subjects had met the study criteria Data were collected through interviews including questionnare iron intake heme and non heme protein and vitamin C used semiquantitative FFQ Anthropometry measurementsto assess the nutritional status and laboratory examination i e blood levels of serum ferritin and CRP and Bifidobacterium in feces Mean age 29 1 5 9 years Median of intake of iron was 66 7 3 3 144 1 mg day serum ferritin was 31 1 3 6 96 1 g L and gut Bifidobacterium 7 45 5 1 9 5 log g feces No significant correlation was found between iron intake and Bifidobacterium in feces r 0 202 p 0 152 and negative correlations and no significant between serum ferritin and Bifidobacterium in feces (r=0, 116, p=0,411)"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tesis Membership  Universitas Indonesia Library
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Candra Nurhayati
"Skripsi ini membahas gambaran, hubungan dan model prediksi berat lahir bayi berdasarkan pertambahan berat badan ibu selama hamil, umur, pendidikan, pekerjaan, Ante Natal Care ( ANC ), jarak kelahiran dan berat badan sebelum kehamilan. Penelitian ini adalah penelitian kuantitatif dengan desain penelitian kohort retrospektif menggunakan data sekunder 2010-2011 dengan 180 sampel. Analisa data meliputi analisa univariat,bivariat, dilanjutkan analisa multivariat.
Hasil penelitian menunjukkan pertambahan berat badan ibu selama hamil mempunyai pengaruh paling besar terhadap berat lahir bayi dikontrol variabel umur ibu, pendidikan, pekerjaan, ANC, jarak kehamilan dan berat badan sebelum hamil. Berdasarkan hasil analisis disarankan memantau pertambahan berat badan selama hamil sehingga dapat meningkatkan berat lahir bayi.

The focus of this study discusses the image, influence and make infants birth weight prediction models based on maternal weight gain during pregnancy with birth weight infants. In addition to birth weight also affected by age, education, occupation, Ante Natal Care(ANC),a distance of pregnancy,and weight before pregnancy. The research design was a retrospective cohort study using secondary data from 2010-2011 with 180 samples in Puskesmas Wonosari, Klaten, Central Java. Data analysis comprised univariate, bivariate and most recsently by multivariate analysis.
The results showed maternal weight gain during pregnancy has the greatest impact on birth weight after controlling by maternal age, education, occupation, frequency of ANC, spacing pregnancies and weight before pregnancy. Based on the results was advised to Puskesmas Wonosari II to health professionals especially midwife to gain capability of monitoring the weight gain during pregnancy, there by increasing infant birth weight."
Depok: Universitas Indonesia, 2012
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UI - Skripsi Open  Universitas Indonesia Library
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Amarylis Febrina Choirin Nisa Fathoni
"ABSTRAK
LATAR BELAKANG: Penilaian aktivitas fisik ibu selama kehamilan sangat penting karena hubungan yang erat antara tingkat aktivitas fisik dan status kesehatan.1 Hubungan erat antara aktivitas fisik sehari-hari dan hasil luaran kehamilan masih belum jelas terungkap karena luasnya variasi desain studi dan langkah-langkah penilaian aktivitas fisik.2 TUJUAN: Untuk melihat sebaran aktivitas ibu hamil pada trimester 3, kemudian melihat adanya hubungan antara aktivitas fisik ibu hamil pada trimester ke-3 dengan metode persalinan, skor APGAR bayi pada menit ke-5, dan berat lahir bayi. Dapat digunakan juga sebagai dasar rekomendasi bagi masyarakat luas mengenai aktivitas fisik selama kehamilan, dan rekomendasi bagi pembuat kebijakan mengenai karyawan yang bekerja di masa kehamilan. METODE: Untuk mengetahui hubungan antara aktivitas fisik ibu hamil dengan luaran ibu hamil dan bayi baru lahir akan digunakan desain potong lintang, dengan melakukan pengamatan secara akurat dan sistematik.HASIL: Penelitian ini melibatkan 100 ibu melahirkan, yang didapatkan bahwa rerata usia responden adalah 27 tahun, dengan nilai tengah paritas adalah 2. Berdasarkan penilaian kuesioner PPAQ didapatkan bahwa nilai tengah akfitivitas mingguan responden adalah 346 MET-jam/minggu dengan nilai tengah tertinggi dilakukan untuk aktivitas ringan Median 143 , dan aktivitas rumah tangga Median 131 . Sedangkan aktivitas olahraga dikerjakan sangat sedikit, dengan nilai tengah 1.63 MET- jam/minggu. Tidak terdapat hubungan antara usia, paritas, jumlah aktivitas fisik dan intensitas terhadap metode persalinan. Pada saat dilakukan uji data numerik, didapatkan bahwa nilai tengah dari kelompok yang melahirkan pervaginam, adalah 341, dan untuk sectio secarea adalah 347.5, perbedaan ini tidak bermakna baik secara klinis maupun statistik p=0.696 . Pada saat analisa untuk melihat faktor yang memengaruhi berat badan, didapatkan bahwa aktivitas dan usia memiliki P ABSTRACT
BACKGROUND The assessment of maternal physical activity during pregnancy is crucial due to the close relationship between the PA levels and the health status.1 The potential relationship between daily physical activity and pregnancy outcome remains unclear because of the wide variation in study designs and physical activity assessment measures.2OBJECTIVES This study was aimed to evaluate the pregnancy daily activities at third trimester and its association between methods of delivery, the fifth minute APGAR score, and birth weight. This study could be used as a basic recommendation for society about daily activities during pregnancy. METHODS This study was a cross sectional study evaluating the association between pregnant women daily activities and maternal and perinatal outcomes by doing systematic and accurate observation.RESULTS Among 100 mother who had delivery, the average of age was 27 years old, and the median of the parity was 2. Based on the assessment of PPA questionnaire, we got the median value of weekly daily activities was 346 MET hours per week which mild activities had the highest point median 143 MET and household activities median 131 MET . However, physical exercises were done infrequently, with median value of 1.63 MET hours per week. There was no significant relationship between age, parity, the amount and intensity of physical activities and methods of delivery. In numerical analysis, we got the median value of physical activities among subjects who had vaginal delivery was 341 MET, and for cesarean section was 347.5 MET. This difference was either not statistically or clinically significant p 0,696 . Physical activities and age had p value below 0,25, therefore they could be included in multivariate analysis. However, both of them were not statictically significant with birth weight. There was no statistically significant association between fifth minute APGAR score and the intensity of physical activities, age, and parity. Meanwhile, babies with fifth minute APGAR score below 7 were mostly delivered by mother having minimal physical activities and there was no significant association between them.CONCLUSION There was no significant association between age, parity, the amount and intensity of physical activities and methods of delivery. And, there was no significant association either between physical activities or age and birth weight. There was no significant association between fifth minute APGAR score and the intensity of physical activities, age, and parity. Babies having fifth minute APGAR score below 7 were mostly delivered by mother having minimal physical activities and had no significant association between them. KEYWORDS pregnancy physical activities, PPA questionnaire "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2017
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UI - Tugas Akhir  Universitas Indonesia Library
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