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"Coronavirus Disease-2019 (COVID-19) merupakan penyakit yang disebabkan oleh coronavirus jenis baru yang menyerang saluran pernapasan. Ketika terkena COVID-19, status pertumbuhan dan perkembangan anak dapat mengalami gangguan dan penyimpangan. Tujuan penelitian ini adalah untuk mengetahui faktor yang berhubungan dengan status pertumbuhan dan perkembangan anak post COVID-19. Penelitian ini menggunakan desain cross sectional yang melibatkan 292 anak balita tiga bulan post COVID-19 dan hasil PCR negatif yang pernah dirawat di salah satu rumah sakit tipe A di Jakarta pada bulan Juli 2021 hingga Desember 2022. Pengambilan sampel menggunakan teknik purposive sampling. Hasil penelitian menunjukkan tidak ada hubungan yang signifikan antara jenis kelamin, komorbid, tingkat keparahan, dan lama rawat dengan status pertumbuhan berat badan sesuai usia. Tidak ada hubungan yang signifikan antara usia, jenis kelamin, komorbid, tingkat keparahan, dan lama rawat dengan status pertumbuhan panjang atau tinggi badan sesuai usia. Tidak ada hubungan yang signifikan antara usia, jenis kelamin, komorbid, tingkat keparahan, dan lama rawat dengan status perkembangan. Ada hubungan yang signifikan antara usia dengan status pertumbuhan berat badan sesuai usia dan panjang atau tinggi badan sesuai usia. Faktor yang paling dominan berhubungan dengan status perkembangan adalah anak laki-laki yang berusia 25 hingga 36 bulan. Ada hubungan yang signifikan antara lama rawat dan komorbid dengan status perkembangan. Faktor yang paling dominan berhubungan dengan status perkembangan anak yakni komorbid. Oleh karena terdapat faktor yang berhubungan dengan status pertumbuhan dan perkembangan anak post COVID-19 maka dapat dilakukan discharge planning terkait tumbuh kembang yang dapat diberikan kepada keluarga, agar keluarga tetap dapat melakukan stimulasi tumbuh kembang. Peneliti merekomendasikan bagi manajemen rumah sakit untuk melakukan optimalisasi pelaksanaan discharge planning terkait tumbuh kembang anak dan bagi dinas kesehatan untuk melakukan optimalisasi pelayanan kesehatan yang ada di komunitas, sehingga anak tetap dapat mendapatkan layanan stimulasi tumbuh kembang yang berkelanjutan setelah anak keluar dari rumah sakit.

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Coronavirus Disease-2019 (COVID-19) is a disease caused by a new type of coronavirus that attacks the respiratory tract. When exposed to COVID-19, the status of a child's growth and development can experience disturbances and irregularities. This study aimed to determine the factors associated with the growth and development status of children post COVID-19. This study used a cross-sectional design involved 292 children under five who had been treated at a type A hospital in Jakarta from July 2021 to December 2022. The sample was taken using a purposive sampling technique. The results showed that there was no significant relationship between gender, comorbidities, severity, and length of stay with weight growth status according to age. There was no significant relationship between age, sex, comorbidities, severity, and length of stay with growth status in length or height according to age. There was no significant relationship between age, sex, comorbidities, severity, and length of stay with developmental status. There is a significant relationship between age and growth status of weight for age and length or height for age. The most dominant factor related to developmental status is boys aged 25 to 36 months. There is a significant relationship between length of stay and comorbidities with developmental status. The most dominant factor related to the child's developmental status is co-morbid. Because there are some factors related to the growth and development status of post-COVID-19 children, discharge planning related to growth and development can be given to families, so that families can continue to stimulate growth and development. Researchers recommend that hospital management optimize the implementation of discharge planning related to children's growth and development and for the health office to optimize health services in the community, so that children can still receive stimulation services for sustainable growth and development after the child is discharged from the hospital."

"Latar Belakang: Post-acute sequelae of COVID-19 (PASC) atau long covid merupakan kondisi dengan gejala jangka panjang yang dialami pasien yang telah pulih pasca infeksi COVID-19 yang bervariasi selama beberapa minggu hingga lebih dari 6 bulan. Kondisi ini dilaporkan terjadi pada 7-91% pasien dengan pasca infeksi akut SARS-CoV-2. Beberapa mekanisme diajukan yang berkontribusi terhadap patogenesis PASC gejala gastrointestinal diajukan di antaranya persistensi virus, disbiosis mikrobial, dan perubahan interaksi neuroimun. Saat ini pandemi COVID-19 sudah dinyatakan sebagai endemi di Indonesia dengan menurunnya jumlah pasien dan pelonggaran protokol kesehatan. Sehingga pada penelitian ini fokus terhadap gejala pasca COVID-19 khususnya gejala gastrointestinal (GI) dengan faktor-faktor yang memengaruhinya.Background: Post-acute sequelae of COVID-19 (PASC), also known as long COVID, is a condition characterized by long-term symptoms experienced by patients who have recovered from a COVID-19 infection, lasting for several weeks to over 6 months. This condition has been reported to occur in 7-91% of patients following acute SARS-CoV-2 infection. Several proposed mechanisms contribute to the pathogenesis of PASC gastrointestinal symptoms, including persistent viral presence, microbial dysbiosis, and altered neuroimmune interactions. Currently, the COVID-19 pandemic is declared as endemic in Indonesia with decreasing numbers of patients. Therefore, this study focuses on post-COVID-19 symptoms, specifically GI symptoms, and the factors influencing them.Objective: To determine the clinical profile of post-COVID-19 gastrointestinal outcomes and the associated factors (age, gender, non-gastrointestinal comorbidities, vaccination status of COVID-19, severity of COVID-19, comorbidities of gastrointestinal diseases, history of COVID-19 complications, nasopharyngeal swab CT-value, neutrophil-to-lymphocyte ratio, SGOT, and SGPT).Methods: This prospective cohort study included 134 subjects diagnosed with confirmed COVID-19 based on nasopharyngeal PCR swab, who received outpatient and inpatient care at RSUPN dr. Cipto Mangunkusumo from October 2022 to March 2023. Statistical analysis was performed using SPSS version 25, with a significance level of p<0.05.Results: Out of 134 study subjects, subjects experienced PASC gastrointestinal symptoms in the first month, and 70 subjects in the third month. The most common manifestations of PASC gastrointestinal symptoms in the first month were constipation and nausea/vomiting in 21 (15.7%) and 10 (7.5%) subjects, respectively, while nausea/vomiting was the most common symptom in the third month. Bivariate analysis revealed significant associations between non-gastrointestinal comorbidities (p=0.011) and CT-value ≥25 (p=0.028) as risk factors for PASC gastrointestinal symptoms in the first month, as well as comorbidities (p=0.022) in the third month. Multivariate analysis found that non-gastrointestinal comorbidities had the most significant influence on PASC gastrointestinal symptoms in both the first and third months, with a relative risk (RR) of 1.608 times (95% CI 1.140 – 2.260; p=0.007) and 2.089 times (95% CI 1.093 – 3.990; p=0.014), respectively.Conclusion: There is a significant association between non-gastrointestinal comorbidities and the occurrence of PASC gastrointestinal manifestations in the first and third months, as well as a CT-value of COVID-19 >25.0 and the occurrence of PASC gastrointestinal manifestations in the first month.Tujuan: Mengetahui profil luaran klinis gastrointestinal pasca COVID-19 dan faktor-faktor yang memengaruhi (usia, jenis kelamin, status vaksinasi COVID-19, komorbiditas non-gastrointestinal, derajat COVID-19, komorbiditas penyakit gastrointestinal, riwayat komedikasi COVID-19, CT-value swab nasofaring, neutrophil-to-lymphocyte ratio, SGOT, dan SGPT)Metode: Desain penelitian berupa studi kohort prospektif pada 134 subjek yang didiagnosis terkonfirmasi COVID-19 dari swab PCR nasofaring yang di rawat jalan dan rawat inap RSUPN dr. Cipto Mangunkusumo selama periode Oktober 2022 sampai dengan Maret 2023. Analisis statistik menggunakan SPSS versi 25, nilai p<0.05 menunjukkan kemaknaan secara statistik.Hasil: Sebanyak 134 subjek penelitian, 64 subjek mengalami gejala gastrointestinal PASC pada bulan ke-1 dan 70 subjek pada bulan ke-3. Manifestasi gejala gastrointestinal PASC terbanyak pada bulan ke-1 yaitu konstipasi dan mual-muntah sebanyak 21 (15,7%) subjek dan mual-muntah 10 (7,5%) pada bulan ke-3. Pada analisis bivariat terdapat hubungan yang bermakna pada subjek dengan riwayat komorbitas (p=0,011) dan CT-value ≥25 (p=0,028) sebagai faktor risiko gejala gastrointestinal PASC pada bulan ke-1 serta subjek dengan komorbiditas non-gastrointestinal (p=0,022) pada bulan ke-3. Analisis multivariat menemukan riwayat komorbiditas non-gastrointestinal paling memengaruhi gejala gastrointestinal PASC pada bulan ke-1 dan ke-3 dengan relative risk (RR) 1,608 kali (IK 95% 1,140 – 2,260; p= 0,007) dan 2,089 kali (IK 95% 1,093– 3,990; p = 0,014).Kesimpulan: Terdapat pengaruh yang signifikan antara riwayat komorbiditas non-gastrointestinal terhadap kejadian manifestasi gastrointestinal PASC bulan ke-1 dan ke-3 serta nilai CT-value COVID-19 >25,0 terhadap kejadian manifestasi gastrointestinal PASC pada bulan ke-1.

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"Penyakit Jantung Bawaan (PJB) sering dikaitkan dengan malnutrisi yang dipengaruhi oleh berbagai faktor yang mengakibatkan peningkatan morbiditas dan mortalitas, penatalaksana yang tepat dapat menurunkan infeksi, lama rawat, bahkan kematian. Penelitian ini dilakukan untuk mengidentifikasi faktor-faktor yang berhubungan dengan status gizi kurang pada anak dengan PJB. Penelitian ini menggunakan observasional analitik dengan rancangan case control.  Sampel penelitian berjumlah 114 anak PJB di Rumah Sakit Jantung Jakarta periode Juli 2020 hingga Juni 2023. Uji statistik menunjukkan tidak ada hubungan antara usia, jenis kelamin, riwayat BBLR, pemberian ASI eksklusif, jenis PJB dan penyakit penyerta terhadap status gizi kurang pada anak PJB, terdapat hubungan antara kelengkapan imunisasi dengan status gizi kurang pada anak PJB (p value <0,05). Simpulan: dari penelitian ini yaitu faktor nutrisi dan organik tidak berhubungan dengan status gizi kurang anak PJB. Oleh karena itu pelayanan perlu memberikan perhatian terkait status nutrisi dan imunisasi disamping masalah jantung.

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Congenital Heart Disease (CHD) is often associated with malnutrition which is influenced by various factors resulting in increased morbidity and mortality, appropriate management can reduce infection, length of stay, and even death. This research was conducted to identify factors associated with malnutrition status in children with CHD. This study used an analytical observational with a case control design. The research sample consisted of 114 CHD children at the Jakarta Heart Hospital for the period July 2020 to June 2023. The result of this study showed that there was no relationship between age, gender, history of LBW, exclusive breastfeeding, type of CHD and comorbidities on malnutrition status in CHD children, there is a relationship between complete immunization and malnutrition status in CHD children (p value <0.05). Conclusion from this research, nutritional and organic factors are not related to the malnutrition status of CHD children. Therefore, services need to pay attention to nutritional status and immunization in addition to heart problems."

"Latar belakang: Penyakit kanker pada anak masih memiliki angka kematian yang tinggi. Pandemi Coronavirus disease 2019 (COVID-19) dapat memperlebar kesenjangan luaran pasien kanker anak di negara berkembang dengan negara maju. Data mengenai pasien kanker anak dengan COVID-19 terkonfirmasi di negara berkembang masih terbatas.Tujuan: Mengetahui prevalens dan luaran pasien kanker anak dengan COVID-19 terkonfirmasi serta faktor yang memengaruhinya agar luaran kanker dapat optimal.Metode: Penelitian ini merupakan studi prognostik dengan desain penelitian kohort retrospektif di rumah sakit rujukan nasional menggunakan data rekam medis. Subyek penelitian adalah pasien kanker anak usia 0-18 tahun dengan COVID-19 terkonfirmasi yang dirawat di pusat COVID-19 - RSCM pada Maret 2020 – Juni 2023. Data deskriptif mengenai prevalens, karakteristik, dan luaran dikumpulkan, dilakukan juga analisis untuk mengetahui pengaruh antara jenis kanker, fase pengobatan, penundaan pengobatan, dan derajat keparahan COVID-19 terhadap luaran.Hasil: Dari 585 pasien kanker anak yang dirawat, 110 (18,8%) di antaranya terkonfirmasi COVID-19 berdasarkan swab PCR SARS-COV-2. Pasien mayoritas berusia 0-5 tahun (39,1%), menderita kanker darah (50,9%), dalam fase pengobatan (88,1%), dan pengobatan tersebut tertunda sebanyak 56,4%. Gejala tersering adalah demam (78,2%), nilai CT PCR terbanyak terdeteksi di bawah 30 (54,6%), dan mayoritas mengalami COVID-19 derajat ringan (55,5%). Tata laksana yang diberikan adalah terapi oksigen (29,1%) dengan penggunaan ventilator sebanyak 8,2% dan dirawat di PICU sebanyak 12,7%, pemberian antivirus (69,1%), antibiotik (80,9%), antiinflamasi (14,5%), dan antikoagulan (22,7%). Sebanyak 19,1% kasus meninggal dan mayoritas terjadi pada 14 hari pertama perawatan. Kesintasan kumulatif adalah 66,1% dan rerata kesintasan selama 40 hari (IK 95% 33,743-46,064). Jenis kanker, fase pengobatan, dan penundaan pengobatan tidak berpengaruh bermakna terhadap luaran kematian. Sementara, derajat keparahan COVID-19 berpengaruh bermakna terhadap luaran kematian dengan HR 4,38 (IK 95% 1,34-14,26; p=0,000) pada derajat sedang/berat dan HR 16,29 (IK 95% 4,83-54,8; p=0,014) pada derajat kritis.Simpulan: Prevalens dan angka kematian pasien kanker anak dengan COVID-19 terkonfirmasi lebih tinggi dibanding COVID-19 pada anak secara keseluruhan, terutama di negara berkembang. Penundaan kemoterapi dapat dipertimbangkan, terutama dalam 14 hari pertama perawatan di rumah sakit.

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Background: Pediatric cancer still has a high mortality rate. The Coronavirus disease 2019 (COVID-19) pandemic has further widened the disparity in pediatric cancer outcomes between developing and developed countries. Limited data exist on the prevalence and consequences of pediatric cancer with confirmed COVID-19 in developing countries.

Objectives: To determine the prevalence and outcomes of these patients and identify influencing factors to optimize cancer outcomes.

Method: This prognostic study employed a retrospective cohort design at a tertiary referral hospital in Indonesia using medical record data. Subjects included pediatric cancer patients aged 0-18 years with confirmed COVID-19 treated at the Kiara COVID-19 Center – dr. Cipto Mangunkusumo Hospital from March 2020 to June 2023. Descriptive data on prevalence, characteristics, and outcomes were collected, along with analysis of the relationship between cancer type, treatment phase, delayed treatment, and COVID-19 severity.

Result: Among 585 pediatric cancer patients treated, 110 (18.8%) were confirmed COVID-19 based on SARS-COV-2 PCR. The majority were aged 0-5 years (39,1%), diagnosed with blood cancer (50,9%), undergoing radio-chemotherapy (88,1%), and delayed treatment 56,4%. Fever was the most prevalent symptom (78.2%), the most CT PCR values were below 30 (54,6%), with 55,5% experiencing mild COVID-19. Management included oxygen therapy (29,1%) with ventilator use (8.2%) and intensive care (12.7%), antiviral (69.1%), antibiotic (80.9%), anti-inflammatory (14.5%), and anticoagulant (22.7%). The mortality rate was 19,1% and the highest number of deaths occurred within 14 days of hospitalization. Cumulative survival was 66.1% and a mean survival was 40 days (95% CI 33.743-46.064). Cancer type, treatment phase, and delayed treatment were not association with mortality outcomes. Meanwhile, COVID-19 severity was associated with mortality outcomes with HR 4.38 (95% CI 1.34-14.26; p=0.000) in moderate/severe COVID-19 and 16.29 (95% CI 4.83-54.8; p=0.014) in critical case.

Conclusion: The prevalence and mortality rates of pediatric cancer with confirmed COVID-19 are notably higher than the general pediatric COVID-19, especially in developing countries. Chemotherapy may be considered postponed, particularly within the first 14 days of hospitalization."

"[Pemantauan pertumbuhan dan perkembangan pada anak balita sangat penting dilakukan untuk mengetahui adanya gangguan pada pertumbuhan dan perkembangan sejak dini. Tujuan penelitianini adalah mengidentifikasi faktor-faktor yang berhubungan dengan pertumbuhan dan perkembangan anak balita. Desain penelitian menggunakan cross sectional, yang melibatkan 100 responden yaitu ibu dan anak balita usia 0-59 bulan di Kota Jambi. Instrumen menggunakan kuesioner tentang karakteristik responden, alat pengukur berat badan, tinggi badan dan lingkarkepala beserta kuesioner, formulir KPSP, kuesioner stimulasi dan pola asuh. Hasil penelitian menunjukkan ada hubungan antara usia anak balita dengan perkembangan (p-value=0,014, α=0,05) dan ada hubungan antara pengetahuan ibu tentang stimulasi dengan perkembangan anak balita (p-value=0,030, α=0,05). Rekomendasi penelitian ini adalah perlunya sosialisasi tentang stimulasi perkembangan anak kepada ibu yang memiliki balita di Kota Jambi.

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The growth and development monitoring for children under five is very important in order to detect the growth and development disorder early on. The purpose of this study was to identify factors correlated with the growth and development of children under the age of five years. The study design was cross-sectional, which involved 100 respondents including mothers and children aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the characteristics of the respondents, body weight and height scale, and head circumference along with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers' knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05). It is recommended to improve the growth monitoring, especially for children under five in Jambi City and to optimize the socialization of the importance of the parent?s roles in providing stimulation to their children;The growth and development monitoring for children under five is very important in order to detect the growth and development disorder early on. The purpose of this study was to identify factors correlated with the growth and development of children under the age of five years. The study design was cross-sectional, which involved 100 respondents including mothers and children aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the characteristics of the respondents, body weight and height scale, and head circumference along with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers' knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05). It is recommended to improve the growth monitoring, especially for children under five in Jambi City and to optimize the socialization of the importance of the parent’s roles in providing stimulation to their children.;The growth and development monitoring for children under five is very important in order to

detect the growth and development disorder early on. The purpose of this study was to identify

factors correlated with the growth and development of children under the age of five years. The

study design was cross-sectional, which involved 100 respondents including mothers and children

aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the

characteristics of the respondents, body weight and height scale, and head circumference along

with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the

development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers'

knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05).

It is recommended to improve the growth monitoring, especially for children under five in Jambi

City and to optimize the socialization of the importance of the parent’s roles in providing

stimulation to their children;The growth and development monitoring for children under five is very important in order to

detect the growth and development disorder early on. The purpose of this study was to identify

factors correlated with the growth and development of children under the age of five years. The

study design was cross-sectional, which involved 100 respondents including mothers and children

aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the

characteristics of the respondents, body weight and height scale, and head circumference along

with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the

development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers'

knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05).

It is recommended to improve the growth monitoring, especially for children under five in Jambi

City and to optimize the socialization of the importance of the parent’s roles in providing

stimulation to their children;The growth and development monitoring for children under five is very important in order to

detect the growth and development disorder early on. The purpose of this study was to identify

factors correlated with the growth and development of children under the age of five years. The

study design was cross-sectional, which involved 100 respondents including mothers and children

aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the

characteristics of the respondents, body weight and height scale, and head circumference along

with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the

development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers'

knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05).

It is recommended to improve the growth monitoring, especially for children under five in Jambi

City and to optimize the socialization of the importance of the parent’s roles in providing

stimulation to their children, The growth and development monitoring for children under five is very important in order to

detect the growth and development disorder early on. The purpose of this study was to identify

factors correlated with the growth and development of children under the age of five years. The

study design was cross-sectional, which involved 100 respondents including mothers and children

aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the

characteristics of the respondents, body weight and height scale, and head circumference along

with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting. The

results showed that there was no correlation between the children under five years of age and the

development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers'

knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05).

It is recommended to improve the growth monitoring, especially for children under five in Jambi

City and to optimize the socialization of the importance of the parent’s roles in providing

stimulation to their children]"

"Pandemi COVID-19 telah terbukti menjadi musuh besar bagi kesehatan global. Kedatangan vaksin membawa angin segar untuk mengembalikan kondisi ke normal. DKI Jakarta sebagai Provinsi dengan jumlah kasus COVID-19 tertinggi di Indonesia merupakan salah satu provinsi prioritas dalam pelaksanaan vaksinasi COVID-19. Capaian vaksinasi Booster ke-I belum sesuai target sedangkan pemerintah sudah melaksanakan vaksinasi Booster ke-II kepada tenaga kesehatan dan lansia. Tujuan Penelitian adalah untuk mengetahui faktor-faktor yang berhubungan dengan kesiapan vaksinasi Booster COVID-19 bagi Masyarakat DKI Jakarta ditinjau dari Health Belief Model. Penelitian ini menggunakan desain studi potong lintang, dilakukan pada November hingga Desember 2022 dengan melibatkan sampel penelitian sebanyak 175 responden. Analisis yang digunakan adalah analisis univariat dan bivariat dengan level kepercayaan 95%. Hasil penelitian menunjukkan bahwa persentase kesiapan vaksinasi pada responden adalah sebesar 84%. Pada faktor pemodifikasi terdapat hubungan antara Usia (p-value 0,000), Pendidikan (p-value 0,727), Pekerjaan (p-value 0,046), dan Pengetahuan (p-value 0,000) dengan kesiapan vaksinasi Booster COVID-19, sedangkan jenis kelamin (p-value 0,727) tidak memiliki hubungan. Pada faktor persepsi terdapat hubungan antara persepsi manfaat (p-value 0,002) dan persepsi hambatan (p-value 0,000) dengan kesiapan vaksinasi Booster COVID-19. Sedangkan persepsi kerentanan (p-value 0,636) dan persepsi keparahan (p-value 0,418) tidak memiliki hubungan. Pada faktor isyarat untuk bertindak terdapat hubungan pada faktor kepercayaan terhadap vaksinasi Booster COVID-19 (p-value 0,000) dan kepercayaan terhadap sumber informasi (p-value 0,000). Sedangkan faktor pengalaman terhadap COVID-19 didapatkan tidak memilki hubungan yang kuat dengan kesiapan Vaksinasi Booster COVID-19 (p-value 1,000). Dari hasil penelitian ini, terdapat beberapa hal yang disarankan, diantaranya menekankan ke masyarakat bahwa pandemi COVID-19 belum berakhir, mengembangkan metode penyebaran informasi yang berkesinambungan dan terus berupaya meluruskan informasi yang menyimpang (hoaks) di kalangan masyarakat.

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The COVID-19 pandemic has proven to be a formidable enemy for global health. The arrival of the vaccine brings fresh air to return conditions to normal. DKI Jakarta as the province with the highest number of COVID-19 cases in Indonesia is one of the priority provinces in the implementation of COVID-19 vaccination. The achievements of the 1st Booster vaccination have not met the target, while the government has carried out the 2nd Booster vaccination for health workers and the elderly. The aim of the study was to determine the factors related to the readiness of the COVID-19 Booster vaccination for the DKI Jakarta Community in terms of the Health Belief Model. This study used a cross-sectional study design, conducted from November to December 2022 involving a research sample of 175 respondents. The analysis used was univariate and bivariate analysis with a 95% confidence level. The results showed that the percentage of readiness for vaccination in the respondents was 84%. In the modifying factors there is a relationship between Age (p-value 0.000), Education (p-value 0.727), Occupation (p-value 0.046), and Knowledge (p-value 0.000) with the readiness of the COVID-19 Booster vaccination, while gender ( p-value 0.727) has no relationship. In the perception factor, there is a relationship between perceived benefits (p-value 0.002) and perceived barriers (p-value 0.000) with the readiness of the COVID-19 Booster vaccination. Meanwhile, perceived susceptibility (p-value 0.636) and perceived severity (p-value 0.418) had no relationship. In cues to action factors there is a relationship between the trust factor of the COVID-19 Booster vaccination (p-value 0.000) and trust of information sources (p-value 0.000). Meanwhile, the experience factor for COVID-19 did not have a strong relationship with the readiness of the COVID-19 Booster Vaccination (p-value 1,000). From the results of this study, there are several suggestions, including emphasizing to the public that the COVID-19 pandemic is not over, developing sustainable and coordinated information dissemination methods, and continuing to work on rectifying distorted information (hoaxes) among the public."

"Latar belakang: COVID-19 menginfeksi semua kelompok umur, namun beban infeksi lebih tinggi dan lebih berbahaya pada kelompok usia lanjut. Pasien yang mengalami infeksi akut COVID-19 juga bisa mengalami gejala menetap yang disebut dengan Sindrom Pasca COVID-19, khususnya pada lansia. Belum ada data yang menunjukkan prevalensi Sindrom Pasca COVID-19 pada lansia di Indonesia dan juga faktor-faktor risiko yang berhubungan dengan kejadian Sindrom Pasca COVID-19 pada lansia.Tujuan: Penelitian ini bertujuan untuk mengetahui seberapa besar prevalensi Sindrom Pasca COVID-19 pada lansia di Indonesia serta meneliti hubungan antara faktor-faktor risiko dengan kejadian Sindrom Pasca COVID-19 dengan menggunakan definisi waktu >4 minggu, >8 minggu, dan >12 minggu.Metode: Penelitian ini merupakan penelitian kohort retrospektif yang menggunakan rekam medis dan wawancara untuk mendapatkan data terkait keberadaan faktor-faktor risiko dan gejala menetap pasca perawatan infeksi akut COVID-19.Hasil: Penelitian ini diikuti oleh 329 pasien lansia (≥60 tahun) yang sempat dirawat akibat COVID-19 di RSCM dan RS Mitra Keluarga Kalideres pada 1 Januari-31 Desember 2021. Prevalensi Sindrom Pasca COVID-19 pada lansia adalah sebesar 31%, 18,24%, dan 10,64% dengan menggunakan definisi waktu >4 minggu, >8 minggu, dan >12 minggu, secara berurutan. Clinical Frailty Scale rawat inap (OR 2,814 [IK 95% 1,172-6,758) dan imobilitas rawat inap (OR 4,767 [IK95% 2,117-10,734]) berhubungan dengan Sindrom Pasca COVID-19 >4 minggu. Selanjutnya, jumlah gejala awal (OR 2,043 [IK95% 1,005-4,153]), konstipasi rawat inap (OR 2,832 [IK95% 1,209-6,633]), imobilitas rawat inap (OR 2,515 [IK95% 1,049-6,026]), dan instabilitas rawat inap (OR 2,291 [IK95% 1,094-4,800) berhubungan dengan Sindrom Pasca COVID-19 >8 minggu. Gangguan pendengaran dan penglihatan follow-up (OR 2,926 [IK95% 1,285-6,665]) dan imobilitas rawat inap (OR 3,684 [IK95% 1,507-9,009]) berhubungan dengan Sindrom Pasca COVID-19 >12 minggu.Kesimpulan: Infeksi akut dengan ≥ 5 gejala, adanya frailty dan sindrom geriatri, khususnya imobilitas saat perawatan, berhubungan dengan Sindrom Pasca COVID-19 pada lansia.

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Background: COVID-19 infects all age groups, but the burden of infection is higher and more dangerous in the elderly. Patients with acute COVID-19 infection can also experience persistent symptoms called Post-Covid-19 Syndrome, especially elderly. No data show the prevalence of Post-Covid-19 Syndrome in the elderly in Indonesia and the risk factors associated with the occurrence of Post-Covid-19 Syndrome in the elderly

Objective: This study aims to determine the prevalence of Post-Covid-19 Syndrome in the elderly in Indonesia and examine the relationship between risk factors and the incidence of Post-Covid-19 Syndrome by using the definition of time > 4 weeks, > 8 weeks. , and >12 weeks.

Methods: This study is a retrospective cohort study that uses medical records and interviews to obtain data regarding risk factors and persistent symptoms after treatment of acute COVID-19 infection.

Results: This study is followed by 329 elderly patients (≥60 years) who had been treated because of COVID-19 at Cipto Mangunkusumo Hospital and Mitra Keluarga Kalideres Hospital from January 1st until December 31st, 2021. the prevalence of Post COVID-19 Syndrome in the elderly was 31%, 18.24%, and 10.64% using the time definition of >4 weeks, >8 weeks, and >12 weeks, respectively. Clinical Frailty Scale during hospitalization scores (OR 2.814 [95% CI 1.172-6.758]) and immobility during hospitalization (OR 4.767 [95% CI 2.117-10.734]) were associated with Post-Covid-19 Syndrome >4 weeks. Furthermore, number of initial symptoms (OR 2,043 [CI95% 1.005-4.153]), constipation during hospitalization (OR 2.832 [CI95% 1.209-6633]), immobility during hospitalization (OR 2,515 [95% CI 1,049-6.026]), and instability during hospitalization (OR 2,291 [CI 95% 1,094-4,800]) was associated with Post-Covid-19 Syndrome >8 weeks. In addition, impairment of visual and hearing during follow-up (OR 2,926 [95% CI 1,285-6,665]) and immobility during hospitalization (OR 3,684 [95% CI 1.507-9,009]) was associated with Post-Covid-19 Syndrome >12 weeks.

Conclusions: Acute infection with ≥ 5 symptoms, frailty, and geriatric syndrome, especially immobility during hospitalization, were associated with Post-Covid-19 Syndrome in the elderly."

"Peningkatan jumlah kasus COVID-19 dan penyebarannya di berbagai negara terjadi berlangsung cukup cepat dan dalam waktu singkat. Hingga 4 Mei 2021, COVID-19 telah menginfeksi lebih dari 152 juta orang dan lebih dari 3 juta kematian di seluruh dunia. Indonesia telah melaporkan 1.682.004 kasus konfirmasi, tertinggi di Asia Tenggara, dan sebanyak 45.949 kematian terkait COVID-19 yang dilaporkan tertinggi ke-2 di Asia dan ke-17 di dunia. Masih terbatasnya data mengenai karakteristik dan faktor risiko yang terkait kematian akibat COVID-19 di Indonesia dan belum ada penelitian mengenai hal ini di kota Medan. Studi kasus-kontrol terhadap 222 pasien COVID-19 yang dirawat inap di RSUP H. Adam Malik Medan periode Maret 2020-Desember 2020 dilakukan menggunakan data rekam medis pasien. Penelitian ini mendeskripsikan karakteristik pasien COVID-19 berdasarkan usia, jenis kelamin, gejala klinis, komorbiditas dan tempat tinggal serta untuk mengidentifikasi faktor-faktor yang berhubungan dengan kematian pada pasien COVID-19. Hasil penelitian melalui analisis multivariat logistik regresi menunjukkan bahwa, adanya peningkatan risiko terhadap kematian pada usia ≥ 60 tahun (OR=5.495, 95% CI: 2.398-12.591), demam (OR=4.441, 95% CI: 1.401- 14.077), sesak napas (OR=8.310, 95% CI: 3.415-20.220), riwayat hipertensi (OR=2.454, 95% CI: 1.159-5.196), riwayat penyakit ginjal kronik (OR=10.460 kali, 95% CI: 3.282-33.331), riwayat penyakit kanker (OR=16.137, 95% CI: 2.798- 96.147) pada pasien COVID-19 yang dirawat inap di RSUP H. Adam Malik Medan Tahun 2020.

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The increase in cases of COVID-19 and its spread in various countries took place very quickly and in a short time. As of May 4, 2021, COVID-19 has infected more than 152 million people and more than 3 million deaths worldwide. Indonesia has reported 1,682,004 confirmed cases, the highest in Southeast Asia, and 45,949 COVID-19-related deaths, the 2nd highest reported in Asia and 17th in the world. Data on characteristics and risk factors related to death from COVID-19 in Indonesia are still limited and there has been no research on this in the city of Medan. A case control study of 222 COVID-19 patients who were treated at H. Adam Malik Hospital in Medan for the period March 2020-December 2020 was carried out using patient medical record data. This study describes the characteristics of COVID-19 patients based on age, gender, clinical symptoms, comorbidities, place of residence and to determines the factors associated with death in COVID-19 patients. The results of the study through multivariate regression analysis showed an increased risk of death at the age of 60 years (OR = 5,495, 95% CI: 2,398-12,591), fever (OR = 4,441, 95% CI: 1,401 -14,077), shortness of breath (OR = 8,310) . , 95% CI: 3,415-20,220, history of hypertension (OR=2,454, 95% CI: 1,159-5,196), history of chronic disease (OR=10,460 times, 95% CI: 3,282-33,331), history of cancer (OR=16,137, 95% CI: 2,798-96,147) in COVID-19 patients treated at H. Adam Malik Hospital Medan in 2020.

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"Pendahuluan: Jumlah penderita dan kasus kematian akibat infeksi virus COVID -19 setiap harinya terus bertambah dan terus muncul varian virus COVID yang baru. Lebih dari 80% kematian karena COVID-19 terjadi pada penderita yang berusia di atas 65 tahun dan memiliki riwayat komorbid. Tujuan penelitian ini untuk mengetahui faktor-faktor yang dapat meningkatkan risiko kematian COVID-19 pada pasien lansia yang melakukan rawat inap di RSUD Karanganyar.Metode: Penelitian ini merupakan studi kuantitatif dengan desain cross sectional menggunakan data sekunder dari file data base rekam medis pasien rawat inap di RSUD Karanganyar yaitu sebanyak 322 pasien lansia. Analisis data dilakukan dengan menggunakan regresi logistik untuk menguji hubungan variabel independen jenis kelamin, TBC paru, diabetes mellitus, ginjal kronis, stroke, dan jantung dengan kematian pasien COVID-19 lansia sebagai variabel dependennya.Hasil: Sebanyak 61 (18,9%) pasien COVID-19 lansia meninggal dunia. Sebanyak 33 (54,1%) pasien lansia adalah perempuan dan 28 (45,9%) laki – laki. Penyakit komorbid yang paling banyak diderita adalah DM 13 (21,3%) ,hipertensi 10 (16,4%), stroke 7 (11,5%), ginjal kronis 5 (8,2%), jantung 5 (8,2%), dan TBC paru yaitu 2 (3,3%) pasien lansia. Hasil uji multivariat menunjukkan riwayat hipertensi memiliki hubungan yang signifikan secara statistik dengan kematian pasien COVID-19 lansia dengan nilai p value 0,022 dan OR 2,647 (95% CI 1,154 – 6,070) sedangkan variabel lain tidak berhubungan.Kesimpulan: Penyakit hipertensi merupakan faktor yang berisiko meningkatkan kematian pasien COVID-19 lansia di RSUD Kabupaten Karanganyar.

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Background: The number of death cases of COVID-19 virus infection increase every day and new variants of the COVID virus continue to emerge. More than 80% of deaths due to COVID-19 occur in patients over the age of 65 and have comorbidities. The purpose of this study was to determine the factors that can increase the risk of death from COVID-19 in elderly patients who are hospitalized at Karanganyar Hospital.

Methods: This research is a quantitative study with a cross sectional design using secondary data from the medical record data base of hospitalized patients at Karanganyar Hospital, as many as 322 elderly patients. Data analysis was performed using logistic regression to examine the relationship between variables of gender, pulmonary tuberculosis, DM, chronic kidney disease, stroke, and heart disease with the death of elderly COVID-19 patients.

Result: A total of 61 (18.9%) elderly COVID-19 patients died. A total of 33 (54.1%) were women and 28 (45.9%) were men. The most common comorbid diseases were DM 13 (21.3%), hypertension 10 (16.4%), stroke 7 (11.5%), chronic kidney 5 (8.2%), heart 5 (8.2 %), and pulmonary tuberculosis in 2 (3.3%) elderly patients. The results of the multivariate test showed that hypertension had a statistically significant relationship with the death of elderly COVID-19 patients with a p value of 0.022 and OR:2.647 (95% CI 1.154 - 6.070) while other variables were not related.

Conclusion: Hypertension is a risk factor for increasing the mortality of elderly COVID-19 patients in Karanganyar District Hospital."

"Pemantauan pertumbuhan dan perkembangan pada anak balita sangat penting dilakukan untuk mengetahui adanya gangguan pada pertumbuhan dan perkembangan sejak dini. Tujuan penelitian ini adalah mengidentifikasi faktor-faktor yang berhubungan dengan pertumbuhan dan perkembangan anak balita. Desain penelitian menggunakan “cross sectional”, yang melibatkan 100 responden yaitu ibu dan anak balita usia 0-59 bulan di Kota Jambi. Instrumen menggunakan kuesioner tentang karakteristik responden, alat pengukur berat badan, tinggi badan dan lingkar kepala beserta kuesioner, formulir KPSP, kuesioner stimulasi dan pola asuh. Hasil penelitian menunjukkan ada hubungan antara usia anak balita dengan perkembangan (p-value=0,014, α=0,05) dan ada hubungan antara pengetahuan ibu tentang stimulasi dengan perkembangan anak balita (p-value=0,030, α=0,05). Rekomendasi penelitian ini adalah perlunya sosialisasi tentang stimulasi perkembangan anak kepada ibu yang memiliki balita di Kota Jambi.

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The growth and development monitoring for children under five is very important in order to detect the growth and development disorder early on. The purpose of this study was to identify factors correlated with the growth and development of children under the age of five years. The study design was cross-sectional, which involved 100 respondents including mothers and children aged 0-59 months in Jambi City. The instrument consisted of a questionnaire about the characteristics of the respondents, body weight and height scale, and head circumference along with the questionnaire, KPSP forms, and the questionnaire of stimulation and parenting.

The results showed that there was no correlation between the children under five years of age and the development (p-value = 0.014, α = 0.05) and there was no correlation between the mothers' knowledge of stimulation and the development of children under five (p-value = 0.030, α = 0.05). It is recommended to improve the growth monitoring, especially for children under five in Jambi City and to optimize the socialization of the importance of the parent’s roles in providing stimulation to their children."