Hasil Pencarian  ::  Simpan CSV :: Kembali

"[, Tujuan penelitian adalah untuk membuktikan hipotesabahwa akan didapat kadar asam sia1at yang lebih tinggi pada serum penderita tumor ganas mata dibandingkan dengan kadar asam sia1at pada penderita tumor jinak mata dan orang normal. Dari pene1itian ini diharapkan dapat ditarik suatu kesimpu1an yang dapat membantu penata1aksanaan diagnosa tumor ganas mata.

---

The purpose of the research is to prove the hypothesis that higher levels of sialic acid will be obtained in the serum of patients with malignant tumors of the eye compared to levels of sialic acid in patients with benign tumors of the eye and normal people. From this study, it is hoped that a knowledge can be drawn that can help in the diagnosis of malignant tumors of the eye.]"

"Latar belakang: Penderita kanker ovarium umumnya datang berobat pada stadium lanjut, sehingga kekambuhan pasca pembedahan dan pemberian kemoterapi mencapai 70-80%. EGFR mengaktifkan jalur sinyal yang menginduksi onkogenesis dan proliferasi sel. Tujuan penelitian ini adalah untuk menganalisis peran EGFR dalam patogenesis tumor serosum ovarium dan peluangnya untuk digunakan sebagai penanda keganasan.Metode: Penelitian ini menggunakan metode potong lintang. Sampel terdiri atas 15 kasus tumor jinak, 15 kasus borderline dan 15 kasus adenokarsinoma di Departemen Patologi Anatomik FKUI/RSCM tahun 2008-2012. Dilakukan pulasan imunohistokimia EGFR dan penilaian dengan H score.Hasil: Terdapat perbedaan ekspresi EGFR yang bermakna antara kelompok tumor serosum jinak (H score = 15), borderline (H score = 60) dan adenokarsinoma (H score = 120), dengan p=0,000.Kesimpulan. Ekspresi EGFR pada tumor serosum ovarium meningkat seiring peningkatan derajat keganasan.

---

Background: Most of ovarian cancer patients are diagnosed in already advanced stage, therefore 70-80% of cases having recurrence after surgical staging and chemotherapy. EGFR activates signaling pathways which induce oncogenesis and cell proliferation. The aim of this study is to analyze the role of EGFR in the pathogenesis of serous ovarian tumors and its possibility to be used as a malignant marker.Methods: This was a cross-sectional study on each 15 cases of benign, borderline and malignant serous ovarian tumors from Anatomical Pathology Department FMUI/CMH in 2008-2012. EGFR status was assessed by immunohistochemistry technique and the expression was evaluated using H score.Results: There was significant difference between EGFR expression in benign (H score = 15), borderline (H score = 60) and malignant serous ovarian tumors (H score = 120), p=0,000.Conclusion: The EGFR immunoexpression was increased along with the higher degree of serous ovarian tumor malignancy."

"Presents pathology in the context of modern cellular and molecular biology and contemporary clinical practice. Suitable for students of medicine and the related health sciences, this title provides comprehensive coverage of disease mechanisms and the pathology of specific disorders ordered by body system."

"Clinical Oral Medicine and Pathology is a clinically relevant and accessible resource for health care professionals that truly bridges the worlds of dentistry and medicine. This handbook of oral medicine and oral pathology serves as a highly readable guide for diagnosis and treatment of commonly encountered oral conditions. The volume is organized by grouping clinical entities under easily recognizable, diagnostically related headings and subheadings and allows the busy clinician to quickly reference and identify a lesion of interest. Concise descriptions of each entity provide background information and treatment recommendations while including specific guidelines on diagnosis, management, and follow-up. The authors of this text both have extensive training in the fields of oral pathology, dentistry, oral surgery and otolaryngology, and provide a comprehensive approach to the practice of oral medicine for all those who are likely to encounter diseases of the oral cavity in their --daily practice." --Book Jacket."