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"AbstrakPURPOSE:Chinese herbal medicine (CHM) has been widely used in China to treat allergic rhinitis (AR). However, several studies have produced conflicting data with regard to the efficacy of the medicine. Our aim was to perform a meta-analysis of randomized clinical trials (RCTs) to evaluate the relative efficacy of CHM.METHODS:We systematically searched the PubMed, Medline, and Springer electronic databases up to March 2017 for RCTs comparing the efficacy of CHM versus placebo for the treatment of patients with AR. Total nasal symptoms and quality of life were assessed through pooling mean difference (MD) with its 95% confidence interval (CI). Moreover, sensitivity and subgroup analyses according to control design and quality of life assessment were performed to evaluate the source of heterogeneity.RESULTS:Eleven RCTs were enrolled in the meta-analysis. Assessment of overall heterogeneity indicated significant heterogeneity among the individual studies (I²=100%, P<0.00001), and thus ransomed effects model was used to pool data. CHM was found to significantly enhance quality of life compared with placebo (MD=-0.88, (95% CI: -1.55, -0.21); P=0.01). The symptom of itchy nose, sneezing or total nasal symptoms scores were not significantly improved after CHM treatment, although the improvement in itchy nose just failed to reach significance (MD=0.09, (95% CI: 0.00, 0.18); P=0.06).CONCLUSIONS:This study suggests that CHM appears to improve the quality of life of AR patients. However, these findings, as well as the findings for the effect of CHM on sneezing, total nasal symptoms, and the symptom of itchy nose, need to be substantiated in larger cohorts of AR patients by further well-designed studies."

"Evidence-based Clinical Practice (EBCP) is the conscientious, explicit, and judicious use of current best external evidence in making decisions about the care of individual patients. In neurology, practice has shifted from a rich, descriptive discipline to one of increasingly diagnostic and therapeutic interventions. Providing a comprehensive review of the current best evidence, Neurology : an evidence-based approach presents this type of evidence in a concise, user-friendly and easily accessible manner. The three co-editors of this important volume are linked in their passion for evidence-based clinical practice in the clinical neurological sciences, connected to a common historical origin at the University of Western Ontario (UWO), London, Ontario Canada and influenced directly by evidence-based medicine teachings of McMaster University, Hamilton, Ontario Cananda. The book is organized in three sections: Basics of Evidence-Based Clinical Practice, with an introduction to the topic, a chapter on the evolution of the hierarchy of evidence, and another chapter on guidelines for rating the quality of evidence and grading the strength of recommendation. The second section, Neurological Diseases, provides an illuminating overview of evidence-based care in ten of the most common areas in neurologic practice. The final, third section provides an outstanding roadmap for teaching evidence-based neurology with a chapter on the evidence-based curriculum. "

"How to search for evidence -- Epidemiology -- Clinical manifestations -- Laboratory tests -- Rational antibiotic use -- Adjunctive treatment -- Bacterial meningitis -- Respiratory tract infections -- Osteomyelitis and septic arthritis -- Urinary tract infections -- Necrotizing enterocolitis and gastrointestinal infections -- Eye infections -- Skin and soft tissue infections -- Bacterial infections -- Mycoplasmas -- Fungal infections -- Viral infections -- Other congenital infections -- Breast milk -- Surveillance -- Infection control -- Developing countries -- Prevention of neonatal infections -- Neonatal antimicrobials."

"In nearly every level of treatment and counseling, care providers must take into account the effects of their patients' diets. Nutrition in Clinical Practice is written to guide health professionals in providing well-informed, compassionate, and effective dietary and weight-management counseling. This fully updated 3rd edition is edited by a leading authority in nutrition and preventive medicine. Practical and evidence-based, chapters address the effects of diet on health and a comprehensive array of illnesses, making it a vital and timely addition to any caregiver's library. Features: NEW data from hundreds of recent studies, NEW section: Contemporary Topics in Nutrition, Easy-reference format includes short chapters, links to current online articles, Contributors representing diverse expertise and practical experience with medical education, nutrition in clinical practice, and preventive medicine, Enhanced coverage of controversial topics, such as, the effects of sugar; health effects of obesity and the 'obesity paradox'; health effects of gluten and grains; nutritional therapy. Appendices includes ancillary materials such as clinically relevant formulas, nutrition data tables, and patient specific meal planners, all fully updated. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: Complete content with enhanced navigation, A powerful search tool that pulls results from content in the book, your notes, and even the web, Cross-linked pages, references, and more for easy navigation, Highlighting tool for easier reference of key content throughout the text, Ability to take and share notes with friends and colleagues, Quick reference tabbing to save your favorite content for future use"

"ABSTRAKAim: to know the effectiveness of probiotic in reducing hepatic inflammation among non-alcoholic fatty liver disease (NAFLD) patients. Methods: we performed literature searching regarding the potential role of probiotic in reducing hepatic inflammation among NAFLD patients. Results: six articles were finally critically appraised. All six studies had good validity and importance. These studies unanimously reported that probiotic is useful in reducing hepatic inflammation, and liver fat content. However, further evidence is needed to show whether or not probiotic is beneficial reducing cirrhosis progression and liver-related mortality. Conclusion: probiotic owns robust potential to treat NAFLD. Probiotic reduce hepatic inflammation, as shown by the reduction of liver aminotransferase, and inflammatory markers. Based on this evidence based report, probiotic is a promising adjunct therapy for NAFLD."

"Pneumonia kemunitas adalah infeksi akut pada paru-paru yang tidak memilki riwayat rawat inap dalam waktu dekat atau tidak terpapar dengan perawatan medis secara teratur. Terdapat dua sistem skoring untuk menentukan prognosis pneumonia komnitas yaitu pneumonia severity index (PSI) and CURB-65. Pnemonia Serverity Index (PSI) lebih rumit dalam penghitungannya dibandingkan CURB-65 dimana PSI menilai 19 variabel sementara CURB-65 hanya 5 variabel. Tujuan menentukan apakah pneumonia serverity index (PSI) score lebih superior dibandingkan skor CURB-65.Metode pencarian literatur dilakukan menggunakan pubmed dan OVID Medline. Literatur dipilih bila tidak lebih lama dari 10 tahun, dan bukan review articel. Enam Literatur memenuhi kriteria dan dimasukan dalam analisis. Hasil lima literatur menyatakan bahwa PSI lebih akurat dalam menentukan dalam prognosis mortalitas 30 hari dan kebutuhan ICU pada pasien risiko tinggi (PSI kelas IV/V and skor CURB-65>3). satu literatur ( Luque et al ) menemukan bahwa CURB-65 sama akuratnya dalam menentukan prognosis mortalitas 30 hari pasien pnemonia komunitas secara keseluruhan. Kesimpulan skor PSI lebih dipilih dibandingkan skor CURB-65 dalam menentukan prognosis mortalitas 30 hari pasien secara keseluruhan pada pasien pneumonia kemunitas."

"This student friendly textbook focuses on the most important topics of psychiatric-mental health nursing, from core concepts to nursing care for specific disorders. The eighth edition is focused on stimulating student critical thinking, thoroughly updated with the latest research."