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"Latar belakang: tumor kelenjar liur merupakan tumor yang jarang pada keganasan kepala leher. Histopatologinya sangat heterogen demikian juga kejadian dan klinik epidemiologinya. Perbedaan karakteristik dari tumor parotis di banyak pusat kesehatan memengaruhi survival rate. Metode: penelitian ini adalah uji retrospektif analitik dengan uji kesintasan. Data didapatkan dari rekam medik pasien tumor parotis ganas yang dirawat di RSUPNCM periode Januari 2005 sampai Desember 2011. Hasil: ada 75 kasus tumor parotis ganas. Laki-laki lebih banyak dibandingkan perempuan, dengan umur rata-rata 50 tahun. Delapan puluh persen ditemukan dalam stadium klinis lanjut. Mukoepidermoid karsinoma merupakan histopatologi yang paling sering ditemukan. Pembedahan merupakan terapi pilihan utama. Enam puluh persen kasus ditemukan penurunan indeks masa tubuh (IMT). Komplikasi tersering adalah paralisis nervus fasialis sekitar 30,7%. Mortalitas dalam 1 tahun didapati sebesar 25,3%. Rekurensi ditemukan sebesar 17,3%. Analisis bivariat antara tatalaksana dengan morbiditas menunjukkan signifikan dengan nilai p=0.001, dan dalam hubungannya dengan mortalitas didapati signifikan dengan tatalaksana, sedangkan stadium klinis dan histopatologi tidak. Histopatologi signifikan dalam hubungannya dengan rekurensi. Pada analisis multivariat antara stadium klinis I-II dengan status nutrisi dan mortalitas menunjukkan hubungan yang signifikan dengan nilai p = 0.006. Terdapat hubungan signifikan antara tatalaksana dengan survival rate, sedangkan untuk jenis kelamin, usia, histopatologi dan stadium klinis tidak ditemukan hubungan yang signifikan. Disease free survival untuk kasus keganasan ini adalah 61,5%. Kesimpulan: karakteristik tumor parotis ganas di RSUPNCM tidak berbeda dengan yang ditemukan pada literatur, hubungan yang signifikan ditemukan antara histopatologi dan tatalaksana sebagai faktor prognosis survival rate.

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Background: salivary gland tumor is a rare case found in head and neck tumor. The histopathology is very heterogeneous, as well as the incident and clinical epidemiology. Different characteristics of parotid gland tumor in many health centers affecting survival rate.

Method: This is a survival study with retrospective analytical method. Data is obtained from medical record in Cipto Mangunkusumo Hospital in period of January 2005 to December 2011.

Results: There are 75 patients with malignant parotid gland tumor. Male is affected more than female, the mean age is 50 years old. 80% of cases found are in late stage. Mucoepidermoid carcinoma is the most frequent histopathology found. Surgery remains the treatment of choice. 60% patients experienced a decreased of body mass index. Postoperative complication such as facial nerve paralysis occurred in 30.7%. One year mortality is found in 25.3% cases. Recurrence is found in 17,3%. Bivariate analysis between clinical management and morbidity has a significant correlation with p=0,001, and significant also found between clinical management with mortality but not for tumor stage and histopathology. Histopathology found significant in correlation with recurrence. Multivariate analysis between nutritional status and tumor stage showed significancy with p = 0.006 in stage I-II. There is significant relationship between clinical management and survival rate, but there is no significancy between sex, age, histopathology, and tumor stage. Disease Free Survival is among 61,5%.

Conclusion: malignant parotid gland tumor in Cipto Mangunkusumo Hospital contributes the same characteristics with those found in publications. There is significant relationship between variables from survival analysis of prognostic factors."

"Introduction: This study aims to know the performance of the Vascular – Physiological and Operative Severity Score for Enumeration of Mortality and Morbidity (V-POSSUM) score as a predictor of 30-day mortality after the Endovascular Aortic Aneurysm Repair (EVAR) – Thoracic Endovascular Aortic Repair (TEVAR) procedure in Abdominal Aortic Aneurysms (AAA) and Thoracic Aortic Aneurysms (TAA) patients in Cipto Mangunkusumo Hospital. Method: This was a retrospective cohort study using data from medical records. Data were taken according to the variables contained in the V-POSSUM scoring system in the patient who undergone EVAR – TEVAR procedure, on the period of 2013 to July 2018. Results: The study involved 85 patients who met the study requirements. It was known that physiological scores, morbidity risk, and mortality risk could be used as a model to predict mortality outcomes because they had good accuracy and discrimination performance, while the severity of the operation score cannot. The result of the goodness of fit model’s physiological score, morbidity risk, and mortality risk was significant (p <0.001), while the severity score of the operation was 0.18 (p >0.05). The Area Under the Curve (AUC) was 94%, 93%, 93%, with the cut points at 31, 68.8, and 10.6 for the physiological score, morbidity risk, and mortality risk, respectively. Conclusion: The V-POSSUM score had good accuracy and discrimination for the physiological score, morbidity risk, and mortality risk."

"Penyakit kolestasis pada bayi dan anak memberikan dampak negatif bagi status nutrisi, pertumbuhan serta perkembangan sehingga berdampak pada mortalitas. Sistem imunitas pada bayi dan anak yang lemah meningkatkan morbiditas dan berdampak pada status nutrisi sehingga meningkatkan angka mortalitas pada anak kolestasis. Penelitian ini dilakukan dengan menggunakan data rekam medis pasien bayi dan anak kolestasis yang dirawat inap serta rawat jalan di Rumah Sakit Cipto Mangunkusumo tahun 2010-2015. Dengan menggunakan desain cohort retrospektif, penelitian ini bertujuan untuk mengetahui hubungan status nutrisi dan morbiditas pada anak dengan kolestasis di Rumah Sakit Cipto Mangunkusumo. Hasil penelitian pengukuran status nutrisi berdasarkan lingkar lengan atas per umur (n=37) didapatkan, status gizi normal 10(27%), gizi kurang 10(27%), dan gizi buruk 17(46%). Dengan pengukuran indeks lingkar lengan atas per umur (LLA/U), hubungan morbiditas common cold memiliki hubungan yang bermakna p<0,05. Namun morbiditas terhadap status nutrisi berdasarkan tinggi badan per umur (TB/U) p>0,05.

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Cholestasis disease in infants and children adversely affects nutritional status, growth and development which impact on mortality. The weak immune system in infants and children can increase morbidity and nutritional status thus increasing the mortality rate in children with cholestasis.

This research was conducted using data from medical records patients of infants and children with cholestatic who are hospitalized and given outpatient treatment at Rumah Sakit Cipto Mangunkusumo 2010-2015.

By using a retrospective cohort design, this research aims to determine the relationship of nutritional status and morbidity in children with cholestasis in Rumah Sakit Cipto Mangunkusumo.

Research results measuring of nutritional status with the index mid upper arm circumference for age (n=37), normal nutritional status 10(27%), under nutrition 10(27%) and severe nutrition 17(46%). With the index mid upper arm circumference for age (MUAC/A), morbidity relationship common cold against nutritional status has a significant relationship p<0.05. However, the morbidity of the nutritional status based high for age (H/A) p> 0.05."

"Latar Belakang: Saat ini, endovascular aneurysm repair (EVAR) lebih diutamakan pada sebagian besar kasus aneurisma aorta abdominalis (AAA) dibandingkan open surgical repair (OSR). Namun, terdapat kontroversi keluaran jangka panjang yang diperlihatkan kedua pilihan tatalaksana tersebut, terutama pada kelompok usia tua. Metode: Tinjauan sistematis dilakukan dengan mengikutsertakan studi yang membandingkan mortalitas jangka panjang, kesintasan jangka panjang, tingkat reintervensi, dan ruptur sekunder antara EVAR dan OSR pada pasien AAA berusia ≥65 tahun dengan minimal follow-up selama dua tahun. Pencarian artikel dilakukan pada empat pangkalan data elektronik yaitu Cochrane, Pubmed, EBSCOHost, dan Scopus. Studi yang diikutsertakan merupakan publikasi dari titik waktu awal yang tidak ditentukan sampai dengan bulan Maret 2024. Telaah kritis melalui instrumen yang sesuai dengan desain studi juga dilakukan untuk memastikan kualitas studi. Keluaran pada setiap studi disintesis ulang, disajikan dalam bentuk tabel, serta dilakukan pembahasan. Hasil: Studi sistematis ini berhasil mengikutsertakan 6 studi, yakni 1 studi meta-analisis dan 5 studi kohort. Mayoritas studi menunjukkan tidak adanya perbedaan mortalitas jangka panjang, kesintasan jangka panjang, tingkat reintervensi, dan tingkat ruptur sekunder antara EVAR dan OSR. Terdapat peningkatan mortalitas dan penurunan kesintasan EVAR dibandingkan OSR pada follow-up sampai dengan tahun keempat, namun tidak ada perbedaan pada tahun kelima dan rerata keseluruhan. Terdapat peningkatan mortalitas dan penurunan kesintasan EVAR pada kelompok usia ≥80 tahun dibandingkan kelompok usia 65-79 tahun. Kesimpulan: Tidak ada perbedaan keluaran jangka panjang antara EVAR dan OSR pada pasien AAA berusia ≥65 tahun.

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Introduction: Nowadays, endovascular aneurysm repair (EVAR) is preferred in most cases of abdominal aortic aneurysm (AAA) than open surgical repair (OSR). However, there are controversies regarding the long-term outcomes of both modalities, especially in the geriatric population. Method: We conducted a systematic review of studies comparing the long-term mortality, long-term survival, reintervention rate, and secondary rupture rate between EVAR and OSR in ≥65-year patients with AAA with a minimum of two years of follow-up. The literature search was conducted in four electronic databases, Cochrane, Pubmed, EBSCOHost, and Scopus, from an undefined start point until March 2024. Studies included also critically appraised with relevant instruments based on the study design. The long-term outcomes of every study were synthesized, presented in tables, and discussed thoroughly. Result: A total of six studies were included, consisting of one systematic review/meta-analysis and five cohort studies. Most studies did not show differences in long-term mortality, long-term survival, reintervention rate, or secondary rupture rate between EVAR and OSR. There was higher mortality and lower survival in EVAR compared to OSR after four years of follow-up, but no differences were found in five years and overall follow-up. There was higher mortality and lower survival after EVAR in patients≥80 years old compared to those 65-79 years old. Conclusion: There are no differences in long-term outcomes between EVAR and OSR in ≥65-year patients with AAA."

"ABSTRACTThe study aimed to investigate the impact of 12 weeks supplementation with multi-micronutrient and iron-folate supplements on hematological status, morbidity and work productivity. Female factory workers were selected as the subjects because: high prevalence of anemia found in this group which might have health and economic consequences since anemia was related to decrease work productivity and decrease resistance to infection, and the increasing number of female workers in developing country.A preliminary study was conducted to investigate the bioavailability of iron from a multi~micronutrient supplement compared to watery ferrous(II)-sulfate solution. In a randomized cross over design, 14 volunteers received 108 mg elemental iron as four tablets of multi-micronutrient supplements (each tablet contained 27 mg elemental iron) or as a solution of 537.60 mg Ferrous(Il)-sulfate. Serum iron concentrations were measured at 0, 2, 4, 6 and 8 hours after dosing. The maximum serum iron level was significantly lower with multi-micronutrient supplement compared to ferrous sulfate solution but the time to reach the peak" serum iron level was not significantly different between those two treatments. The median relative bioavailability of iron in multi-micronutrient supplement was 32.22%The main study was conducted in a shoe factory, West Java. A total of 308 subjects were selected and divided randomly into three groups that respectively received multi-micronutrient (each tablet contained 27 mg elemental iron), iron-folate supplements (each tablet contained 200 mg ferrous sulfate equal to 60 mg elemental iron) and placebo. Multimicronutrient supplements and placebo were given time times per week and iron-folate supplements were given once a week. All of the supplementations were supervised and last for 12 weeks. Hematological assessed in sub sample of each group based on Willingness; making a total of 140 subjects.Significant increments in the levels of hemoglobin, serum ferritin, and serum retinol were observed in multi-micronutrient group (0.6 g/dl, 13.44 ug/l, and 0_6 pmol/l respectively) and iron-folate group (0.3 g/dl, 11.26 ug/l, and 0.4 umolfl respectively); the increments were higher in multi-micronutrient group but not statistically different from iron-folate group. In the placebo group, hemoglobin level was decreased by 0_3 g/dl, serum ferritin was increased by 4.28 ug/1, and serum retinol was relatively constant. The prevalence of anemia and low iron status were decreased after treatment with multi-micronutrient (7% and 20.5%, respectively) or iron-folate supplements (91% and 12.8%, respectively). The anemia prevalence in placebo group was increased by 6.6% while the prevalence of low iron status was decreased by 2.5%. The morbidity was increased in all groups with the lowest increment was observed in multi-micronutrient group (65% in multi-micronutrient group compared to 14.1% in iron group and 22.4% in placebo group). The work productivity was increased by 6.3% in iron group and 3.6% in multi-micronutrient group while it was relatively constant in placebo group. In conclusion, multi-micronutrient supplement had better impact on hematological status and reducing morbidity level compared to iron-folate supplement that had better impact on work productivity."

"ABSTRAKLatar belakang: Penelitian ini bertujuan untuk mengetahui mortalitas danmorbiditas pada pasien elektif dalam daftar tunggu serta gambaran waktu tunggupasien elektif dalam daftar tunggu operasi bedah pintas koroner dikaitkan denganketersediaan sumber daya (sistem, sumber daya manusia dan fasilitas) UPF BedahJantung Dewasa, RS Jantung dan Pembuluh Darah Harapan Kita.Metode : Penelitian ini menggunakan desain studi kuantitatif dan kualitatif. Datakuantitatif dikumpulkan secara prospektif selama 2 bulan sejak bulan Agustus-September 2010.Hasil : Dari 58 pasien tersebut, 1 pasien meninggal selama menunggu dan 1pasien terkena stroke selagi menunggu. Tidak terdapat sistem khusus atau skoringuntuk menentukan waktu tunggu pada pasien. Belum terdapat sistem penjadwalan,termasuk metode memasukan pasien kedalam daftar, memutuskan statuskegawatan, menjadwalkan tanggal masuk dan memindahkan pasien dari daftaryang adekuat.Kesimpulan : Kejadian mortalitas dan morbiditas selama waktu tunggu tidakditemukan sebagai kejadian yang sering terjadi selama menunggu operasi bedahpintas koroner pada studi ini. Namun sulit mengabaikan kerjadian yang terjadipada kedua pasien pada penemuan, apalagi hasil penelitian menguatkan bahwabelum terdapat sistem penentuan waktu tunggu dan penjadwalan yang adekuat diUPF Bedah Jantung dan Intermediate Bedah Dewasa RS.Jantung dan PembuluhDarah Harapan Kita walaupun sementara ini sumber daya yang ada (baik fisikmaupun sumber daya manusia) masih dirasakan cukup mengakomodir jumlahkasus yang ada.

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ABSTRACTBackground: This study is aimed to find out mortality and morbidity in electivepatient while waiting and description of waiting time in elective patient related toresources needed (system, human resources and facility) at department ofcardiovascular surgery, Harapan Kita Hospital.Method : This study is use quantitative and qualitative desain study. Thequantitative data collected prospectively within 2 months since August untilSeptember 2010.Result : From 58 patients, 1 patient was died while waiting and 1 fall into stroke.There?s no adequate system in scheduling patient, including put the patient intothe list of que, decide the urgency and remove the patient from the list.Conclusion : It?s known that morbidity and mortality is not found as a significantevent happened while waiting for CABG in this study. It?s difficult to ignore thethings happened to the 2 patient, especially after knowing there?s no adequatesystem to decide wait time and scheduling at Department of cardiovascularsurgery, Harapan Kita Hospital, while resources is still"

"Proses adaptasi dan interaksi dari peserta didik dengan lingkungan baru dapat mengakibatkan gangguan keseimbangan fisiologis tubuh sehingga menjadi rentan terhadap penyakit. Penelitian potong lintang ini bertujuan untuk mengidentifikasi determinan epidemiologi penyakit pada mahasiswa Akademi Keperawatan Pemerintah Kabupaten Garut tahun 2015. Sebanyak 235 mahasiswa menjadi sampel. Data yang dikumpulkan meliputi karakteristik responden, karakteristik tempat asal mahasiswa, kesakitan dengan menggunakan kuesioner tentang riwayat kesakitan atau mobiditas. Hasil penelitian menunjukkan bahwa 70,2% mahasiswa mengalami sakit selama tiga bulan terakhir dan 57,9% mahasiswa memiliki riwayat sakit terdahulu. Terdapat hubungan antara determinan epidemiologi karakteristik responden dengan nilai p= 0,023 dengan 95% CI sebesar 6,48 (2,21–22,56) dan karakteristik tempat pada kesakitan mahasiswa nilai p= 0,045 dengan 95% CI sebesar 0,09 (0,02–0,41). Peran pembimbing akademik perlu ditambah dengan memberikan bimbingan dan penyuluhan terhadap masalah kesehatan mahasiswa. Institusi pendidikan sangat penting memiliki dan menyimpan pangkalan data tentang kesakitan mahasiswa.

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The process of adaptation and interaction of students with the new environment can result in physiological balance disorders of the body, thus becoming susceptible to disease. This cross-sectional study aimed to identify the epidemiological determinants of disease in 2015 Garut District Nursing Academy students. A total of 235 students were involved. Data collected included respondent characteristics, the characteristics of the place of origin of the students, morbidity using a questionnaire about the history of previous illness or morbidity. The results showed that 70.2% of students experienced pain during the last three months and 57.9% of students had a history of the previous disease. There was a relationship between the epidemiological determinant of the characteristics of respondents with a value of p= 0.023 with 95% CI of 6.48 (2.21–22.56) and place characteristics in the morbidity of students p= 0.045 with 95% CI of 0.09 (0.02–0.41). The role of academic advisers needs to extend by providing guidance and counseling on student health problems. Educational institutions are significant to have and keep a database of the morbidity of students."

"Diare merupakan salah satu penyebab tingginya morbiditas dan mortalitas anak di Indonesia. Salah satu faktor risiko terjadinya diare dan meningkatkan risiko anak untuk dirawat inap adalah kurang pengetahuan ibu. Penelitian ini bertujuan untuk mengidentifikasi pengaruh pendidikan kesehatan terhadap kemampuan ibu merawat anak diare. Penelitian ini merupakan studi kuasi eksperimen dengan rancangan post-test only with group control design. Sampel penelitian sebanyak 62 responden di dua rumah sakit di Denpasar. Hasil post-test menggambarkan bahwa skor pengetahuan, sikap, dan keterampilan masingmasing kelompok berbeda secara bermakna (p< 0,05) dan ibu pada kelompok intervensi mampu merawat anak diare, berbeda secara bermakna dengan kelompok kontrol (p= 0,000; α= 0,05). Pendidikan kesehatan perawatan anak diare hendaknya diberikan secara intensif guna mendukung terlaksananya konsep family centered care dalam asuhan keperawatan anak di rumah sakit.

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Diarrhea is one of the causes of high morbidity and mortality of children in Indonesia. One risk factor for diarrhea and increased risk for hospitalized children is the lack of maternal knowledge. The study aimed to identify the effect of health education for maternal ability in caring for child with diarrhea. This research was a quasi-experimental study, using control group post-test only design. Study sample was 62 respondents in two hospitals in Denpasar. The results indicated that posttest scores of knowledge, attitudes and skills of each group were different significantly (p< 0.05). Mothers in the intervention group capable of caring for child with diarrhea, significantly different to those in the control group (p= 0.000; α= 0.05). Health education about diarrhea in children should be given intensively to support the implementation of family centered care concept in pediatric nursing at hospital."