Hasil Pencarian  ::  Simpan CSV :: Kembali

"ABSTRACTpain is one of the most often symptoms experienced by patients with advanced or chronic diseases which can cause a decrease in the quality of life of palliative patients. Pain in palliative patients has not yet received enough attention, especially factors associated with pain and its management. This study aimed to determine the factors associated with pain in palliative patients and also assess whether there is a two-way relationship between psychological factors and pain. In addition, we will also see whether spiritual services play a role in relieving pain. Methods: cross-sectional study were used and secondary data were obtained from medical records of 285 palliative patients at Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. The data were processed to determine the psycho-socio-demographic characteristics, the reciprocal relationships of psychological and pain aspects, and the relationship of pharmacological therapy (opioids), non-pharmacological therapy (spiritual services), and combination of both therapies in pain management. Results: of the 285 palliative patients, 60.3% had pain, which was found more in cancer patients (74.4% vs 25.6%). Pain was found more in patients aged 41-60 years (51.1%), women (51.2%), and unemployed (30.2%). The severity of the pain was found to be significant in patients with depressive symptoms (p=0.045), while patients with anxiety symptoms (p=0.155) and sleep disorders (p=0.619) had no significant relationship. Pain experienced by palliative patients was not statistically significant in causing depression (p=0.058), anxiety (p=0.107), and sleep disorder (p=0.639). Moreover, pain management with opioids, spiritual services, or combination of them turned out to have significant results (p=0.022). Conclusion: pain in palliative patients is mainly experienced by cancer patients and the elderly. Psychological factors affect the condition of pain, so the management that includes biopsychosocial aspect will be able to reduce pain significantly."

"ABSTRAKLatar Belakang: Eksaserbasi pada PPOK mempunyai kontribusi yang besar terhadap derajat keparahan dan progresivitas PPOK. Identifikasi faktor-faktor yang berhubungan dengan eksaserbasi PPOK banyak diteliti di luar negeri. Dengan mempertimbangkan terdapatnya perbedaan karakteristik pasien di Indonesia, maka perlu dilakukan penelitian tentang faktor-faktor yang berhubungan dengan eksaserbasi pada pasien PPOK di Indonesia.Tujuan: Mengetahui prevalensi eksaserbasi pada pasien PPOK di RSCM selama kurun waktu 1 Januari 2010 sampai dengan 31 Desember 2012 serta untuk mengidentifikasi faktor-faktor yang berhubungan dengan eksaserbasi pasien-pasien PPOK yang berobat di RSCM baik rawat jalan maupun rawat inap.Metode: Penelitian ini merupakan studi dengan desain potong lintang pada pasien PPOK yang berobat di RSCM selama tahun 2010–2012. Data klinis dan penunjang selama perawatan diperoleh dari rekam medis. Analisis bivariat dilakukan pada variabel kelompok usia, riwayat merokok, komorbiditas, derajat PPOK, riwayat pengobatan dengan kortikosteroid, dan frekuensi eksaserbasi dalam satu tahun sebelumnya.Variabel yang memenuhi syarat akan disertakan pada analisis multivariat dengan regresi logistik.Hasil: Sebanyak 184 pasien diikutsertakan dalam penelitian ini. Didapatkan prevalensi eksaserbasi PPOK sebesar 70,7%. Derajat PPOK , riwayat perokok, frekuensi eksaserbasi satu tahun sebelumnya, pengobatan kortikosteroid sistemik, dan komorbid merupakan variabel yang berbeda bermakna pada analisis bivariat. Faktor risiko independen yang bermakna pada analisis multivariat adalah frekuensi eksaserbasi PPOK dalam satu tahun sebelumnya ≥ 2 kali (OR 27,39; IK 95% 3,30 sampai 227,29; p = 0,002), perokok aktif (OR 5,11; IK 95% 1,07 sampai 24,35; p = 0,041), PPOK derajat III dan IV (OR 4,71; IK 95% 1,59 sampai 13,97; p = 0,005), dan komorbid dengan nilai Charlson Comorbid Index lebih dari dua (OR 4,09; IK 95% 1,37 sampai 12,18; p = 0,011). Sedangkan pengobatan dengan kortikosteroid sistemik merupakan faktor proteksi terhadap eksaserbasi PPOK (OR 0,12; IK 95% 0,03 sampai 0,54; p = 0,006).Simpulan: Prevalensi eksaserbasi pasien PPOK di RSCM pada tahun 2010 sampai dengan 2012 adalah 70,7%. Faktor risiko eksaserbasi PPOK adalah frekuensi eksaserbasi PPOK pada satu tahun sebelumnya lebih dari sama dengan dua kali, perokok aktif, PPOK derajat III dan IV serta komorbid dengan Charlson Comorbid Index . Sedangkan pengobatan dengan kortikosteroid sistemik merupakan faktor proteksi terhadap eksaserbasi PPOK.

---

ABSTRACTBackground. Exacerbation in chronic obstructive pulmonary disease (COPD) contributes greatly to the severity and progression of COPD. Identification of factors associated with exacerbation of COPD has widely studied abroad with varying results. Due to difference in patient characteristic, it is necessary to study on the factors associated with exacerbation of COPD in Indonesia.Aim.To determine the prevalence of COPD exacerbations in RSCM during 2010 until 2012. And to identify factors associated with exacerbation of COPD patients who seek treatment at Cipto Mangunkusumo Hospital, both inpatient and outpatient.Methods. This study was a cross sectional study design in COPD patients who seek treatment at CiptoMangunkusumo Hospital, both inpatient and outpatient, during 2010-2012. Clinical data, supportive data, and outcome (exacerbation or stable) data during treatment were obtained from medical records. Bivariate analyses were performed on age, history of smoking, comorbidity, severity of COPD, history corticosteroids treatment, and frequency of exacerbations in the previous year. Variables that were eligible would be included in the multivariate analysis in the form of logistic regression.Results. A total of 184 patients enrolled in this study. Prevalence of COPD exacerbation was 70.7%. Severity of COPD, history of smoking, frequency of previous exacerbations, history of systemic corticosteroid treatment, and comorbidity were variables found to be significantly different in bivariate analysis. Independent risk factors that were found to be significant in multivariate analysis were ≥ 2 times of COPD exacerbation in the previous year (OR 27.39; 95% CI 3.30 to 227.29; p = 0.002), current smoker (OR 5.11; 95% CI 1.07 to 24.35; p = 0.041), grade III and IV of COPD (OR 4.71; 95% CI 1.59 to 13.97; p = 0.005), and comorbid with charlson comorbid index value more of two (OR 4.09; 95% CI 1.37 to 12.18; p = 0.011). While treatment with systemic corticosteroid is protective factor against COPD exacerbations (OR 0.12; 95% CI 0.03 to 0.54; p = 0.006).Conclusion. The prevalence of COPD exacerbations in RSCM during 2010 to 2012 is 70.7%. Risk factors for COPD exacerbation are more than or equal to two times of COPD exacerbation in the previous year, current smokers, grade III and IV of COPD and comorbid with charlson comorbid index value more of two. While treatment with systemic corticosteroid is protective factor against COPD exacerbations."

"Pendahuluan: Nyeri kronik merupakan fenomena biopsikososial yang kompleks yang berlangsung lebih dari 3 hingga 6 bulan dengan intensitas nyeri yang persisten. Merupakan salah satu masalah kesehatan terbesar di dunia.. Hasil penelitian multisenter 14 Rumah Sakit pendidikan yang dilakukan Pokdi Nyeri PERDOSSI tahun 2002 didapatkan 4.456 kasus nyeri dimana 9,5% diantaranya adalah nyeri neuropatik. Nyeri neuropatik dikenal sebagai salah satu kumpulan gejala yang sulit diidentifikasi dengan tatalaksana yang suboptimal. Tujuan: Didapatkannya instrumen kuesioner painDETECT versi Indonesia yang valid dan reliabel. Metode: Penelitian dengan menggunakan studi validasi transkultural ISPOR disertai analisis validasi kriteria dan uji reliabilitas konsistensi internal dan tes retes secara guided interview menggunakan kuesioner painDETECT. Hasil: Didapatkan 150 sampel dengan nyeri kronik berdasarkan skor kuesioner painDETECT versi Indonesia, 75 pasien dengan nyeri nosiseptif, 42 pasein dengan nyeri campuran dan 33 pasien dengan nyeri neuropatik. Pada analisis validasi kriteria didapatkan korelasi tinggi dengan instrumen standar emas LANSS (r= 0,082,p<0,001), AUC 85,5%, sensitivitas 78,3% dan spesifisitas 78,7% dengan titik potong optimal ≥17. Pada uji reliabilitas konsistensi internal didapatkan nilai Alpha Cronbach 0,710 dan nilai reliabilitas tes retes 0,96. Simpulan: Didapatkannya kuesioner painDETECT versi Indonesia yang valid dan reliabel dengan nilai sensitivitas dan spesifisitas yang baik dalam menapis komponen nyeri neuropatik.

---

Background: Chronic pain is a complex biospsychosocial phenomena. Pain that lasting more than 3 to 6 months with persistence intensity. Representing one of the biggest health problem in the world. Based on the results of a multicentre study in 14 Education Hospital, PERDOSSI Pain Study Group conducted in 2002 found 4,456 pain cases in which 9.5% were neuropathic pain. Whereas neuropathic pain is known as one of the hardest to overcome which are often missed identified and causing a suboptimal treatment.

Objective: To develop an Indonesian version of PainDETECT Questionnaire (PDQ-Ina) and assess its validity and reliability.

Methode: Using ISPOR transcultural validation study and criteria validation analysis followed with reliability internal consistency test and test retest based on PDQ guided interview.

Result: There were 150 subjects with chronic pain. Divided in to 3 types of group based on Indonesian version PDQ scoring, 75 patients having nociceptive pain, 42 were mixed pain and 33 patients having neuropathic pain. Within validation criteria analysis there were high correlation between PDQ-Ina with LANSS instrument as gold standard (r= 0,082,p<0,001), AUC 85,5%, sensitivity 78,3% and specificity 78,7% with the optimal cut off point ≥17. The reliability of internal consistency Cronbach’s Alpha value were 0,710 and the test retest realibility were 0,96.

Conclusion: The Indonesian version of the PDQ is a valid and reliable scale and have a good sensitivity and specificity to be used to determine neuropathic component of chronic pain."

"Diabetes Melitus (DM) adalah masalah kesehatan yang besar merupakan penyebab penting dari angka kesakitan, kematian, kecacatan, dan kerugian ekonomi di seluruh dunia termasuk Indonesia. Provinsi DKI merupakan provinsi DM tertinggi secara nasional. Tujuan penelitian ini adalah mengetahui faktor risiko yang berhubungan dengan diabetes Melitus berdasarkan surveilans penyakit tidak menular tahun 2018. Penelitian ini menggunakan desain Cross sectional. Data dari surveilans Faktor Risiko PTM Suku Dinas Kesehatan Jakarta Pusat tahun 2018. Sampel yang dianalisis sebesar 115.475 respoden berumur ≥ 15 tahun. Hasil analisis menunjukkan prevalensi DM sebesar 2,8% dan terdapat hubungan antara sumur, pendidikan, pekerjaan, jenis kelamin, riwayat keluarga, konsumsi sayur dan buah, aktivitas fisik, merokok, obesitas abdominal, hipertensi dan status perceraian dengan DM berdasarkan surveilans penyakit tidak menular. Perlu adanya peningkatan kualitas pelayanan surveilans PTM dari pemerintah serta kesadaran warga Jakarta Pusat yang berumur ≥ 15 tahun untuk pemantauan faktor risiko serta deteksi dini PTM.

---

Diabetes mellitus (DM) is a major health problem that is an important cause of morbidity, mortality, disability, and economic losses worldwide including Indonesia. DKI Province is the highest DM province nationally. The study study aims to determine the risk factors associated with diabetes mellitus based on surveillance of non-communicable diseases in 2018. This research used a cross sectional design. Data from NDC Risk Factor Central Jakarta Health Surveillance 2018. The samples analyzed were 115,475 respondents aged ≥ 15 years.DM prevalence of 2.8% and there was a relationship between wells, education, employment, gender, family history, vegetable and fruit consumption, physical activity, smoking, abdominal obesity, hypertension and divorce status with DM based on non-communicable disease surveillance. It was necessary to improve the quality of NDC surveillance implementation from the government and  the awareness of Central Jakarta citizens aged ≥ 15 years for risk factor monitoring and early detection of NDC."

"Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan pemanfaatan Program Pengelolaan Penyakit Kronis (Prolanis) di BPJS Kesehatan Kantor Cabang Jakarta Timur tahun 2015. Penelitian ini merupakan jenis kuantitatif dengan menggunakan data primer dan desain studi cross sectional. Hasil yang didapatkan adalah sebanyak 53,4% responden memiliki tingkat pemanfaatan yang tinggi dan 46,6% memiliki tingkat pemanfaatan yang rendah. Variabel yang ditemukan memiliki hubungan yang signifikan dengan pemanfaatan Prolanis yaitu pendidikan, dukungan keluarga, dukungan dokter dan manfaat Prolanis, masing-masing dengan besar p value 0,015; 0,002; 0,025 dan 0,005. Sedangkan karakteristik umur, jenis kelamin, diagnosis medis, variabel jarak dan waktu tempuh, keseriusan, kerentanan penyakit dan hambatan Prolanis tidak ditemukan hubungan yang signifikan dengan pemanfaatan Prolanis.

---

The purpose of this research is to determine factors associated with the utilization of chronic disease management program at BPJS Kesehatan, Branch Office, East Jakarta, 2015 using cross sectional method. Data was collected primary and supported by structured questionnaire. The results shows that 53.4% of respondents have a high utilization rates and 36.6% have a low utilization rate. The variables that were found to have a significant relationship with the utilization of Prolanis are education, family support, doctor support and the benefits of Prolanis, each with p value 0,015; 0,002; 0,025 and 0,005. Characteristic, accessibility to primary health care, perceive of seriousness and vulnerability of diseases, and barriers variables have no significant relationship with the utilization of Prolanis."

"Penyakit tidak menular (PTM) merupakan penyakit yang memiliki klaim pembiayaan tertinggi dari Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan) pada tahun 2016. Direktorat Pencegahan dan Penyakit Tidak Menular (Dit. PPTM) mempunyai program untuk pemberdayaan masyakat atau Unit Kesehatan Berbasis Masyarakat (UKBM) yang bernama Posbindu PTM. Posbindu PTM merupakan kegiatan berbasis masyarakat dalam upaya menjaga kesehatan dari PTM. Dalam pelaksanaanya Posbindu PTM mencatat data faktor risiko PTM yang melalui wawancara seperti merokok, konsumsi buah dan sayur, konsumsi alkohol, dan aktivitas fisik, pemeriksaan gula darah, tekanan darah, indeks masa tubuh (IMT), dan beberapa pemeriksaan penunjang lain. Pemeriksaan tersebut dicatat dalam sistem informasi surveilans Posbindu PTM. Saat ini belum ada visualisasi data untuk sistem tersebut. Tujuan dari penelitian ini adalah untuk memvisualisasikan data faktor risiko PTM dari sistem tersebut. Penelitian ini mengambil data faktor risiko PTM di Provinsi Jawa Timur pada tahun 2016. Hasil penelitian ini adalah adanya visualisasi data faktor risiko PTM yang dapat membantu melihat data menjadi informasi berbasis wilayah.

---

Non-communicable disease (PTM) is a disease that has the highest financing claim from the Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan) in 2016. The Directorate of Prevention and Non-Communicable Diseases (Dit. PPTM) has a program for community empowerment or Community Based Health Unit (UKBM ) named Posbindu PTM. Posbindu PTM is a community-based activity in an effort to maintain the health of PTM. In the implementation of Posbindu PTM recorded data on PTM risk factors through interviews such as smoking, fruit and vegetable consumption, alcohol consumption, and physical activity, examination of blood sugar, blood pressure, body mass index (BMI), and several other investigations. The examination was recorded in the Posbindu PTM surveillance information system. At present there is no data visualization for the system. The purpose of this study is to visualize PTM risk factor data from the system. This study took the PTM risk factor data in East Java Province in 2016. The results of this study were the visualization of PTM risk factor data that could help see data into region-based information."

"Karya ilmiah akhir (KIA) ini merupakan laporan praktik residensi keperawatan medikal bedah yang terdiri dari pengelolaan kasus kanker dengan pendekatan chronic illness trajectory model, penerapan evidence based nursing penggunaan kipas angin untuk mengurangi sensasi dispnea dan melakukan proyek inovasi tentang pemantauan dan deteksi dini perburukan kondisi pasien menggunakan Modified Early Warning Score (MEWS). Konsep trajectory meyakini penyakit kronis memiliki suatu lintasan yang berbeda-berbeda dari waktu ke waktu sesuai fasenya dan dapat dikelola, serta berfokus pada perawatan suportif tanpa mengabaikan perawatan langsung pada pasien, sehingga dapat digunakan untuk pasien kanker yang akan membantu meningkatkan kemandirian dan kualitas hidup pasien. Penggunaan kipas angin efektif mengurangi sensasi dispnea pada pasien kanker, bersifat sederhana, murah, tanpa efek samping dan portable sehingga dapat dijadikan sebagai bagian dari perawatan di rumah atau paliatif. MEWS dapat dijadikan sebagai alat triase karena bersifat sederhana, membantu pemantauan parameter fisiologis pasien secara terstandar. Namun keefektifannya di bidang onkologi masih perlu dilakukan penelitian lebih lanjut.

---

This final paper is a report of residency medical surgical nursing practice consisting of the management of the cancer cases with the approach of the chronic illnes trajectory models, application of evidence based nursing using fan to reduce dyspnea and innovation project on monitoring and early detection of deterioration patient?s conditions using the modified early warning score (MEWS). The concept of trajectory believe that chronic disease have trajectory, is different time to time according to the phase and can be shape, as well as focusing on supportive care without neglecting the direct care. So it is suitable for cancer patients which will help to improve the independence and patient?s quality of life. Dyspnea management using the fan is effective to reduce the dyspnea in cancer patient, simple, cheap, no adverse effect and portable so it can be used as parf of the palliative treatment. MEWS can be used as a triage tool because it is simple, helping to monitor physiological parameters of patients are standardized. The implementation and effectiveness in the oncology still needs further investigation."

"Latar Belakang: Aspergilosis paru kronik (APK) dapat menjadi komplikasi infeksi tuberkulosis (TB) paru yang telah diobati. Gejala klinis APK dengan TB paru sangat mirip, sehingga sulit dibedakan. Diagnosis APK ditetapkan sesuai konsensus berdasarkan gejala klinis, hasil pemeriksaan radiologi dan laboratorium mikologi. Pemeriksaan antibodi dengan imunoglobulin G (IgG) spesifik Aspergillus menggunakan metode Enzyme-linked immunosorbent assay (ELISA) dapat membantu diagnosis APK. Penelitian ini bertujuan untuk mengetahui karakteristik klinis, profil IgG spesifik Aspergillus, serta prevalensi APK pada pasien bekas TB di beberapa rumah sakit di Jakarta.Metode: Penelitian prospektif dengan desain potong lintang ini dilakukan pada April 2019 - Februari 2020. Pemilihan subjek dilakukan dengan metode consecutive sampling. Subjek merupakan pasien bekas TB yang berasal dari poli rawat jalan dan rawat inap Rumah Sakit Umum Pusat Rujukan Respirasi Persahabatan Jakarta dan Rumah Sakit Graha Permata Ibu. Pemeriksaan IgG spesifik Aspergillus dan biakan sputum jamur dilakukan di Laboratorium Departemen Parasitologi FKUI.Hasil: Dari 97 pasien yang sesuai dengan kriteria penerimaan, 66 pasien (68%) berjenis kelamin laki-laki dan rerata usia 51,8±13,6 tahun. Gejala klinis lebih dari 3 bulan yang dilaporkan berupa mudah lelah (38,4%), sesak napas (34,02%), batuk (30,93%), hemoptisis (27,84%), penurunan berat badan (23,71%), dan nyeri dada (19,6%). Gambaran radiologi terkait APK berupa ektasis (57,8%), kavitas (27,8%), penebalan pleura (26,8%), fibrosis parakavitas (18,6%), dan bola jamur (6,2%). Hasil pemeriksaan IgG spesifik Aspergillus positif dilaporkan pada 51 pasien (52,6%), sedangkan biakan sputum jamur Aspergillus didapatkan pada 43 pasien (44,3%). Berdasarkan analisis hasil-hasil pemeriksaan tersebut, diagnosis APK ditegakkan pada 28 pasien (28,9%).Kesimpulan: Profil IgG spesifik Aspergillus pada 97 pasien bekas TB dalam penelitian ini menunjukkan hasil positif pada 51 pasien (52,6%). Gejala klinis lebih dari 3 bulan yang dilaporkan berupa batuk lama, hemoptisis, penurunan berat badan, mudah lelah, dan sesak napas. Gambaran radiologi terkait APK berupa ektasis, kavitas, penebalan pleura, fibrosis parakavitas, dan bola jamur. Prevalensi APK berdasarkan hasil-hasil pemeriksaan tersebut adalah 28,9%.

---

Introduction: Chronic pulmonary aspergillosis (CPA) might become a complication of pulmonary tuberculosis (TB) that has been treated. The clinical symptoms of CPA can resemble with PTB, making it difficult to distinguish. The diagnosis of CPA is determined by the consensus based on clinical symptoms, radiological features, and mycological results. Antibody detection with Aspergillus- specific immunoglobulin G (IgG) using the Enzyme-linked immunosorbent assay (ELISA) method can contribute to CPA diagnosis. This study aims to determine the clinical characteristics, Aspergillus-specific IgG detection, and the prevalence of CPA in prior TB patients at several hospitals in Jakarta.

Method: This prospective cross-sectional study was conducted in April 2019 - February 2020. Patients recruitment was carried out by consecutive sampling method. Subjects were prior TB patients at Persahabatan National Respiratory Referral Hospital and Graha Permata Ibu Hospital. Detection of Aspergillus- specific IgG and fungal cultures from sputum were carried out in the Laboratory of the Parasitology Department, FMUI.

Results: Of 97 patients recruited according to inclusion criteria, 66 patients (68%) were male and the mean age was 51.8 ± 13.6 years. The clinical symptoms of more than 3 months were fatigue (38.4%), shortness of breath (34.02%), cough (30.93%), hemoptysis (27.84%), weight loss (23, 71%), and chest pain (19,6%). Radiological features associated with CPA were ectasis (57.8%), cavity (27.8%), pleural thickening (26.8%), para-cavitary fibrosis (18.6%), and fungal ball (6.2%). The Aspergillus-specific IgG positive were reported in 51 patients (52.6%), whereas Aspergillus sputum cultures were found in 43 patients (44.3%). Based on the analysis of those examinations, the diagnosis of CPA was determined in 28 patients (28.9%).

Conclusion: The detection of Aspergillus-specific IgG in 97 prior TB patients showed the positive results in 51 patients (52.6%). The clinical symptoms more than three months were fatigue, shortness of breath, cough, hemoptysis, and weight loss. The radiological features related to CPA were ectasis, cavitary lesions, pleural thickening, paracavitary fibrosis, and fungal ball. The prevalence of CPA based on those examinations was 28.9%."

"Latar belakang: Indonesia memiliki beban tuberkulosis (TB) paru tinggi. Aspergilosis paru kronik (APK) sering ditemukan pada pasien TB. Diagnosis APK menjadi tantangan di Indonesia karena keterbatasan sumber daya. Diperlukan alat diagnostik yang mudah, murah, dan memberikan hasil cepat dengan akurasi baik untuk membantu menegakkan diagnosis APK. Penelitian ini bertujuan untuk mengetahui nilai diagnostik ICT Aspergillus pada pasien TB paru.Metode: Penelitian ini berdesain potong lintang dan merupakan bagian dari penelitian payung tentang diagnosis APK pada pasien TB paru di Jakarta. Serum pasien TB paru yang memenuhi kriteria inklusi diperiksa menggunakan ICT Aspergillus (LDBio, Diagnostics, Lyon, France) dan IgG Spesifik Aspergillus ELISA (Bordier affinity products, Crissier, Switzerland) sesuai protokol di Laboratorium Mikologi Departemen Parasitologi FKUI pada Februari-November 2021.Hasil: Dari 105 subjek penelitian yang memenuhi kriteria inklusi, sebanyak 58,1% adalah laki-laki. Rerata usia pasien 47,1617,1 tahun. Proporsi hasil positif ICT Aspergillus adalah 10,5% dan IgG spesifik Aspergillus ELISA 43,8%. Sensitivitas ICT Aspergillus 23,9%, dengan spesifisitas 100%, nilai duga positif 100%, dan nilai duga negatif 62,8%.Kesimpulan: Kemampuan diagnostik ICT Aspergillus belum optimal sebagai alat skrining, tetapi dapat dipertimbangkan sebagai alat diagnosis pasien TB paru suspek APK pada daerah dengan sumber daya terbatas.

---

ackground: Indonesia has high pulmonary tuberculosis (TB) burden. Chronic pulmonary aspergillosis (CPA) is common in pulmonary TB patients. Diagnosing CPA is challenging in Indonesia because of the limited resources available. A new rapid and robust diagnostic tool is needed. This research aims to evaluate the diagnostic value of the ICT Aspergillus in pulmonary TB patients.

Methods: This cross-sectional study is a part of the CPA diagnostic research of pulmonary TB patients. Pulmonary TB patients' serum fulfilling the inclusion criteria were assessed using ICT Aspergillus (LDBio, Diagnostics, Lyon, France) and Aspergillus-specific IgG ELISA (Bordier affinity products, Crissier, Switzerland) in Mycology Laboratory of Parasitology Department FMUI in February-November 2021.

Results: From 105 subjects included, the proportion of men 58,1% with 47,1617,1 years age means. The Aspergillus IgG was positive in 10,5% patients with ICT, and 43,8% with ELISA. The sensitivity of ICT Aspergillus was 23,9%, the specificity was 100%, the positive predictive value was 100%, and the negative predictive value was 62,8%.

Conclusion: ICT Aspergillus has a fair diagnostic capacity in pulmonary TB patients as screening tools for CPA. However, the usage of ICT Aspergillus as point-of-care test in limited-resource settings needs to be considered."

"

Penyakit ginjal kronis merupakan masalah kesehatan global yang dapat menimbulkan beban mortalitas dan morbiditas yang substansial. Hasil Riskesdas 2018 menunjukkan bahwa Provinsi Jawa Barat merupakan salah satu provinsi dengan jumlah pasien PGK tertinggi di Indonesia, dengan prevalensi yang lebih tinggi dari nasional, yaitu 0,48%. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian penyakit ginjal kronis pada penduduk usia ≥35 tahun di Provinsi Jawa Barat. Penelitian dilakukan dengan desain studi cross-sectional menggunakan data sekunder dari Riskesdas 2018. Sampel penelitian ini adalah seluruh penduduk usia ≥35 tahun di Provinsi Jawa Barat. Terdapat sebanyak 32.044 sampel yang memenuhi kriteria inklusi dan eksklusi penelitian. Hasil penelitian menunjukkan prevalensi kejadian penyakit ginjal kronis pada penduduk usia ≥35 tahun di Provinsi Jawa Barat adalah 0,6%. Faktor yang berhubungan dengan kejadian penyakit ginjal kronis adalah usia ≥60 tahun (nilai p=0,001; POR=1,662; 95% CI: 1,23-2,25), jenis kelamin laki-laki (nilai p=0,013; POR=1,431; 95% CI: 1,08-1,89), diabetes (nilai p=0,000; POR=3,770; 95% CI: 2,39-5,96), penyakit jantung  (nilai p=0,000; POR=2,725; 95% CI: 1,60-4,63), dan aktivitas fisik (nilai p=0,015; POR=1,521; 95% CI: 1,08-2,14).

---

Chronic kidney disease is a global health problem that can cause a substantial burden of mortality and morbidity. The 2018 Riskesdas results show that West Java Province is one of the provinces with the highest number of CKD patients in Indonesia, with a higher prevalence than the national one, which is 0.48%. This study aims to determine the factors associated with the incidence of chronic kidney disease in people ages ≥35 years in West Java Province. The research was conducted using a cross-sectional study design using secondary data from the 2018 Riskesdas. The sample for this study was all residents ages ≥35 years in West Java Province. There were 32.044 samples that met the inclusion and exclusion criteria of the study. The results showed that the prevalence of chronic kidney disease in people ages ≥35 years in West Java Province was 0.6%. Factors associated with the incidence of chronic kidney disease were age ≥60 years (p-value=0.001; POR=1.662; 95% CI: 1.23-2.25), male gender (p-value=0.013; POR =1.431; 95% CI: 1.08-1.89), diabetes (p-value=0.000; POR=3.770; 95% CI: 2.39-5.96), heart disease (p-value=0.000; POR=2.725; 95% CI: 1.60-4.63), and physical activity (p-value=0.015; POR=1.521; 95% CI: 1.08-2.14).

 

 

"