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Raden Kusumadewi
"Latar Belakang: Prolaps organ panggul (POP) pada wanita menimbulkan morbiditas. Untuk mengurangi angka re-operasi dan meningkatkan kualitas hidup pasien dibutuhkan peningatan kualitas pelayanan secara terus menerus. Guideline yang saat ini secara luas dipakai dalam penatalaksanaan POP di Indonesia adalah Panduan Penatalaksanaan POP PB HUGI-POGI pada tahun 2013. Penelitian ini dilakukan bertujuan untuk mengetahui insidensi POP dan melakukan audit kesesuaian pada penatalaksanaan kasus POP di RSUPN Cipto Mangunkusumo tahun 2016-2018.
Metode: Penelitian ini merupakan penelitian deskriptif dengan menggunakan desain penelitian cross-sectional menggunakan data sekunder. Sampel yang digunakan dalam penelitian ini adalah pasien POP yang didiagnosis dan mendapat tatalaksana di Polikinik Uroginekologi RSUPN Cipto Mangunkusumo pada bulan Januari 2016 sampai dengan Desember 2018, diikuti oleh wawancara pasien yang dipilih secara acak tentang follow up pasca operasi.
Hasil: Terdapat 252 kasus prolaps organ pelvis di tahun 2016-2018 dengan prevalensi 15,96%. Proporsi kesesuaian anamnesis tatalaskana POP konservatif dan operatif adalah 88,1% dan 82,8%, pemeriksaan fisik 93,1% dan 97,3%, 100% pada informasi pemilihan tatakasana dan informed consent. Kepatuhan follow up 6 bulan dan 12 pasca operasi adalah masing-masing 40,4% dan 26,5%. Ketidakcocokan dalam anamnesis dan pemeriksaan fisik disebabkan oleh beberapa formulir penilaian yang harus diisi serta formulir penilaian uroginekologi yang tidak terlampir dengan catatan medis pasien.
Kesimpulan: Panduan usulan pelayanan asesmen pasien POP dengan penulisan pada formulir asesmen uroginekologi yang telah diperbaharui dan mengintegrasikan ke dalam rekam medik menjadi usulan berdasarkan hasil audit.

Background: Pelvic organ prolapse (POP) in women causes significant morbidity. In order to reduce the number of re-operations and improve the quality of life of patients, consistent quality of patient care is required. The Executive Board of the Urogynecology Association of the Indonesian Obstetrics & Gynecology Associations 2013 POP guideline is widely used in Indonesia, but compliance to the guidelines needed to be evaluated. This study aimed to investigate the incidence of POP and to audit POP management in Cipto Mangunkusumo General Hospital, Indonesia, in 2016-2018.
Method: This was a cross-sectional study on the medical records of POP patients who were diagnosed and treated at the Urogynecology Outpatient Clinic, Cipto Mangunkusumo General Hospital in January 2016 to December 2018, followed by randomly selected patient interview about follow-up discrepancy.
Results: There were 252 cases of POP in 2016-2018, with a prevalence of 15.96%. Proportion of conformities in POP management with conservative and operative management was 88.1% and 82.8% in history taking, 93.1% and 97.3% in physical examination, both 100% in examinations and informed consent. Compliance of 6 months and 12 months follow up in operative management was 40.4% and 26.5%, respectively. Mismatches in history taking and physical examination were due to multiple assessment forms that have to be completed as well as unintegrated urogynecology assessment form with patients medical record.
Conclusion: Our audit suggests that urogynecology assessment form should be integrated into patients medical records is needed to improve patient care. A patient book should be provided to improve follow-up rates.
"
Depok: Fakultas Kedokteran Universitas Indonesia, 2020
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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Kartika Indah Lestari
"ABSTRAK
Latar Belakang: Prolaps Organ panggul POP adalah tonjolan atau penonjolan organ panggul dan segmen yang terkait vagina ke dalam atau melalui vagina.1 POP Sering dijumpai pada wanita dewasa dan usia lanjut.1-3 Umumnya wanita yang menderita POP datang dengan keluhan adanya benjolan pada vaginanya.9,10 Gangguan pada fungsi seksual jarang dikeluhkan, namun dari kepustakaan diketahui bahwa pasien prolaps stage 3-4 terkait dengan sulitnya pencapaian orgasme.13 Sedangkan Roovers dkk melaporkan prevalensi disfungsi seksual sebesar 68 pada pasien POP. Sayangnya, Di Indonesia sendiri penelitian mengenai disfungsi seksual pada penderita POP cukup jarang, bahkan peneliti sendiri belum mendapatkan datanya. Oleh karena itu penting dilakukan penelitian mengenai prevalensi disfungsi seksual pada pasien prolaps organ panggul.Tujuan : Mengetahui prevalensi disfungsi seksual pada penderita prolaps organ panggulMetode: Dengan desain potong lintang, di dua rumah sakit pusat rujukan di Jakarta RSUPN Ciptomangunkusumo dan RSUP Fatmawati . Semua pasien POP yang memenuhi kriteria inklusi mengisi kuesioner indeks fungsi seksual FSFI-19 , kemudian dilakukan analisis data univariat untuk karakteristik data subjek, dan bivariat untuk mengetahui hubungan antara variable dependen dan independen.Hasil: Dari 82 data yang dianalisis, prevalensi disfungsi seksual pada pasien POP mencapai 57,3 . Sedangkan sebagian besar pasien POP juga sudah mengalami menopause dengan prevalensi sebesar 76.8 . Prevalensi disfungsi seksual pada pasien POP yang sudah menopause sebesar 66,7 . Dari hasil analisis bivariat, usia, menopause, obesitas dan stadium prolaps adalah faktor risiko yang signifikan terhadap kejadian disfungsi seksual pada pasien POP. Variabel usia, merokok, menopause, obesitas dan stadium prolaps, memiliki nilai p 60 dengan OR 8 IK95 2,45- 26,12 , dan obesitas IMT 30 kg/m2 dengan OR 0,30 IK 95 0,09-0,98 .Kata kunci : prolapse organ panggul, disfungsi seksual, fungsi seksual, seksual aktif

ABSTRACT
AbstractBackground Pelvic Organ Prolapse POP is a bulge or protrusion of pelvic organs and related segments into or through the vagina vagina.1 POP often be found in adult women and older people.1 3 Generally, women who suffer from POP present with a lump vaginal .9,10 Disturbances in sexual function rarely complained, but from the literature it is known that patients with stage 3 4 prolapse associated with difficulty in achieving a orgasme.13 While Roovers et al reported the prevalence of sexual dysfunction was 68 in patients with POP. Unfortunately, in Indonesia, research on sexual dysfunction in patients with POP quite rare, even the researchers themselves do not get the data. It is therefore important to do research on the prevalence of sexual dysfunction in patients with pelvic organ prolapse and factors associated with sexual dysfungtion among them.Objective To determine the prevalence of sexual dysfunction in patients with pelvic organ prolapse and factors associated with sexual dysfungtion among them.Methods A cross sectional design, in two referral hospitals in Jakarta RSUPN Ciptomangunkusumo and Fatmawati Hospital All patients who met the inclusion criteria POP fill out a questionnaire of sexual function index FSFI 19 , then performed univariate analysis of data on the characteristics of the data subject, bivariate and multivariate analysis to know the relationship between the dependent and independent variablesResults Of the 82 analyzed data, the prevalence of sexual dysfunction in patients with POP reached 57.3 . While most of the patients had experienced menopause POP also with a prevalence of 76.8 The prevalence of sexual dysfunction in patients who are menopausal POP by 66.7 . From the results of the bivariate analysis, age, menopause, obesity and stage of prolapse is a significant risk factor on the incidence of sexual dysfunction in patients with POP. The variables of age, smoking, menopause, obesity and stage of prolapse, p 60 with an OR 8 IK95 2,45 26.12 , and obesity BMI 30 kg m2 with an OR of 0.30 CI 95 0.09 to 0.98 . Keywords pelvic organ prolapse, sexual dysfunction, sexual function, sexually active"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
T58898
UI - Tesis Membership  Universitas Indonesia Library
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Finish Fernando
"Latar Belakang: Prolaps Organ Panggul (POP) dikelompokkan menjadi prolaps dinding anterior, posterior dan puncak vagina. 40% wanita dengan POP dinding anterior vagina memiliki elongasio serviks yang akan mempengaruhi tatalaksana pembedahan POP. Terdapat beberapa alat untuk mengukur panjang serviks, diantaranya Pelvic Organ Prolapse Quantifications System (POP-Q), dengan mengukur perbedaan titik C dan D. Sampai saat ini belum terdapat penelitian yang menguji sensitivitas, spesifisitas dan akurasi pemeriksaan POP-Q dalam mengukur panjang serviks untuk mendiagnosis elongasio serviks pada pasien POP. Tujuan: Diketahuinya nilai sensitivitas, spesifisitas dan akurasi POP-Q untuk menilai panjang serviks sebagai diagnosis elongasio serviks pada pasien POP dengan baku emas pengukuran anatomi serviks dari hasil histerektomi. Metode: Uji diagnosis, potong lintang, consecutive sampling. Data diambil dari pemeriksaan POP-Q dan pengukuran anatomi serviks dari hasil histerektomi.
Hasil: 66 subjek, 1.5% POP derajat 2, 45.5% POP derajat 3 dan 53.0 % POP derajat 4. Rerata (± sb) usia dan indeks massa tubuh (IMT) berturut-turut 59.88 tahun (± 9.347) dan 24.41 (± 3.67) kg/m2. Median (min-maks) PS POPQ dan PS Anatomi berturut-turut 4 cm (1-12) dan 5 cm (3-10). Sensitivitas, Spesifisitas dan Akurasi POP-Q berturut-turut 79%, 58% dan 68%.
Kesimpulan: Pemeriksaan POPQ memiliki spesifitas yang baik (79%) tetapi dengan sensitivitas yang kurang baik (58%) dan akurasi 68% untuk diagnosis elongasio serviks pada prolaps organ panggul.

Background: Pelvic Organ Prolapse (POP) categorized as anterior, posterior and apical prolapse. 40% women with anterior POP have cervical elongation. Cervical elongation will make difference in surgical POP treatment. There are several tool for measure cervical length, one of them is Pelvic Organ Prolapse Quantifications System (POP-Q), by measure difference in point C and D. Until now, there is no research to measure sensitivity, specificity and accuracy of POP-Q to measure cervical length for cervical elongation diagnose in POP patients. Objective: To know sensitivity, specificity and accuracy of POP-Q to measure cervical length for cervical elongation diagnose in POP patients with gold standard was anatomical cervical length from hysterectomy result.
Methode: Diagnosis research, cross sectional, consecutive sampling. POP-Q was taken before operation and anatomi cervical length was from hysterectomy result.
Result: 66 subject, 1.5% 2nd degree POP, 45.5% 3rd degree POP, and 53.0 % 4th degree POP. Mean (± sd) age and body mass index consecutively 59.88 years (± 9.347) and 24.41 (± 3.67) kg/m2. Median (min-max) cervical length POP-Q and anatomy consecutively 4 cm (1-12) and 5 cm (3-10). Sensitivity, Spesifisity dan Accuracy POP-Q consecutively 79%, 58% dan 68%.
Conclussion: POPQ has good specificity (79%) but with less sensitivity (58%) with accuracy 68% to diagnose cervical elongation in POP.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Ihya Ridlo Nizomy
"Latar Belakang: Inkontinensia urin (IU) menurut ICS didefinisikan sebagai keluarnya urin yang tidak dapat dikendalikan atau dikontrol, yang secara obyektif dapat diperlihatkan dan merupakan suatu masalah sosial dan higienis. Pada perempuan, gangguan fungsi berkemih ini sering kali didapatkan pasca-operasi koreksi kelainan Prolaps Organ Panggul (POP). Inkontinensia Urin Tekanan de novo (IUT de novo) adalah IU yang terjadi pada pasien POP pasca-operasi pervaginam yang tidak didapatkan sebelum operasi.
Tujuan: Untuk mengetahui kejadian IUT de novo dan faktor risiko yang berhubungan pada pasien POP pasca-operasi pervaginam di Divisi Uroginekologi dan Rekonstruksi Departemen Obstetri dan Ginekologi RSCM Jakarta.
Metode: Studi klinis potong lintang yang dilakukan pada 75 orang pasien POP pasca-operasi pervaginam di Divisi Uroginekologi dan Rekonstruksi Departemen Obstetri dan Ginekologi RSCM Jakarta pada bulan Januari 2016 sampai Juli 2017. Penilaian kejadian IUT de novo dan faktor risiko yang berperan dilakukan berdasarkan data Rekam Medik, lembar penilaian Kuesioner QUID (Questionnaire for Urinary Incontinence Diagnosis) versi Indonesia dan dikonfirmasi dengan pemeriksaan Cough Stress Test secara kualitatif dan tes pembalut pad test secara kuantitatif.
Hasil: Dari 75 subyek penelitian didapatkan angka kejadian IUT de novo sebesar 8% (6/75). Uji analisis statistik menunjukkan hanya 2 faktor risiko yang berperan secara bermakna (p < 0,05) terhadap kejadian IUT de novo pada pasien POP pasca-operasi pervaginam di RSCM Jakarta, yaitu derajat POP yang berat dan penyakit Diabetes Mellitus dengan nilai OR 0,13 (95% CI 0,02-1,63) dan 23,75 (95%CI 2,29-590,2).
Kesimpulan: Pada penelitian ini, angka kejadian IUT de novo pada pasien POP pasca-operasi pervagnam adalah 8% dengan faktor risiko yang berperan adalah derajat POP preoperatif yang berat dan penyakit Diabetes Mellitus.

Background: Stress Urinary Incontinence remains a main women's health problem due to its devastating impacts to the quality of life. Some patients with pelvic organ prolapse (POP) may suffer from stress urinary incontinence (SUI) named de novo SUI after pelvic floor reconstruction2. The epidemiology study of de novo SUI in Indonesia is not known yet. In the world, a few studies have reported a wide range (2-43%) in incidence of de novo SUI following surgical repair of POP in previously continent patients. This study aimed to investigate the occurrence of de novo SUI and determined related risk factors after vaginal surgery on POP patients in Ciptomangunkusumo Hospital Jakarta. Methods: This is a cross-sectional study of 108 patients who underwent pelvic floor vaginal surgery due to pelvic organ prolapse (POP) at the Department of Obstetry and Gynecology, Urogynecology and Recontruction Division in Indonesian University-Ciptomangunkusumo Hospital from January 2016 to December 2017. According to the inclusion and exclusion criteria, 75 patients were enrolled in the study with consecutive sampling technique. The occurrence of de novo SUI was determined 6-12 months postoperatively by using Indonesian version of Questionnaire for Urinary Incontinence Diagnosis (QUID), and objectively by positive Cough Stress Test (CST) during gynecological examination after negative Preoperative Prolapse Reduction Stress Test (PPRST). The clinical characteristic of positively de novo SUI patients identified were age, parity, Body Mass Index, menopause periode before surgery, degree of Pelvic Organ Prolapse based on POP-Q system, type of vaginal surgery and clinical result of Diabetes Mellitus. Thes significant risk factors that contribute for the occurrence of de novo SUI determined by multivariate statistical analysis (95% CI and 𝛼 0.05).
Results: The occurrence of de novo SUI was 8% or 6 from 75 patiens 6-7 month postoperative for pelvic floor reconstruction due to POP. Average of age, parity, BMI, menopause periode before surgery, respectively were 56.17 ± 4.67, 3.17 ± 1.07, 28.58 ± 5.18, and 12,8 ± 7,0. There were 50,0% (3/6) patients with severe degree of POP and 50% (3/6) with mild degree of POP with most of them 66,7% (4/6) had underwent non colpocleisis procedure for POP reconstruction. All of the patient but one were positively Diabetes Mellitus according to clinical hystory and laboratory finding, and most of them about 83,3% (5/6) were in menopause state. There were two significant risk facors that contribute to the occurrence of de novo SUI which are severe degree of preoperative POP (p 0.038; OR 0.13 95% CI 0,02-0,63) and Diabetes Mellitus (p 0.02; OR 23.75 95% CI 2.29-590.2).
Conclusion: The occurrence of de novo SUI after vaginal surgery of Pelvic Organ Prolapse patients in Ciptomangunkusumo Hospital Jakarta was 8%. Most of them were average of age < 60 years old, parity < 4, non- obese women, in menopausal periode, and diabetic patient. The determinant significant risk factors contribute to the occurrenceof de novo SUI were evere degree of preoperative POP and Diabetes Mellitus."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Ario Legiantuko
"Latar belakaog : Prevalensi penderita prolaps organ panggul (POP) terus bertambah, seiring dengan angka harapan hidup yang meningkat. Berbagai studi telah dilakukan untuk melihat terapi pasien POP. Pesarium merupakan pitihan utama terapi POP, tetapi sampai saat ini sangat sedikit literatur yang membahas evaluasi penggunaan jangka panjangnya. Tujuan : Mengetahui perbaikan kualitas hidup pasien POP yang diterapi dengan pesarium, dibandingkan sebelum pemasangan dengan bulan ketiga dan keenam pasca pemasangan. Metode : Pasien POP yang bersedia ikut penelitian akan diberikan kuesionar dengan cara anamnesis terpimpin. Kuesioner yang digunakan adalah Pelvic Floor Distress 111Ventoryshort form 20 (PFDI-20) dan Pelvic Floor Impact Questionnaire-shortform 7 (PFIQ-7) yang sudah diterjemahkan. Setelah pemasangan berhasil, akan dilakukan follow up pada bulan ketiga dan keenam pasca pemasangan, serta dilakukan penilaian efek samping penggunaan pesarium, yaitu keluhan saluran kemih bagian bawah, vaginitis, dan erosi vagina. Basil : Terdapat 51 SP ikut serta dalam penelitian, dengan 45 SP meneruskan penggunaan pesarium setelah menyelesaikan penelitian dan 6 SP melanjutkan terapi operasi. Penilaian kualitas hidup mendapatkan hasil bermakna pada bulan ketiga dan keenam dibandingkan dengan awal penelitian, baik dengan kuesioner PFDI-20 maupun PFIQ-7. Kesimpulan : Terdapat perbaikan kualitas hidup pasien POP setelah penggunaan pesarium selama 6 bulan.

Background: Prevalence of womens with pelvic organ prolapse have increased by day, correspond to higher life expectancy. There are many study that observe the best treatment for pelvic organ prolapse. Pessary is one of them, but until now only few literature tells about the effect of this treatment for improving quality of live. Objective: To understand the improvement of quality of life in women with pelvic organ prolapse, before and after six months pessary treatment. Methods: Womens presenting for pessary insertion completed both Pelvic Floor Distress Inventory-short form 20 (PFDI-20) and Pelvic Floor Impact Questionnaire-short form 7 (PFIQ-7). After successful pessary insertion, subjects were reviewed after 3 and 6 months treatment. Result: There were 51 subjects enrolled in this study, with 45 subjects continued the used of pessary after fmished the study and 6 subjects were changed into surgery. There were statistically and clinically significant improvements of quality of life, after 3 and 6 months treatment with pessary, both using PFDI-20 and PFIQ-7 questionnaire. Conclusion: The use of pessary for 6 months reduces symptoms and improves the quality of life in women with pelvic organ prolapse."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
T58020
UI - Tesis Membership  Universitas Indonesia Library
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Anthonyus Natanael
"Latar belakang: Prolaps organ panggul (POP) didefinisikan sebagai turunnya visera pelvis (uterus, kandung kemih, uretra, dan rektum) dari posisi normal. Otot levator ani merupakan penopang panggul yang berperan penting dalam patogenesis POP. Studi sebelumnya menunjukkan terdapat perbedaan luas area hiatus dan panjang anteroposterior hiatus levator ani pada setiap derajat keparahan POP. Diagnosis POP dapat ditegakkan dengan POP-Q, namun pelaksanannya masih terbatas sehingga dibutuhkan alat pemeriksaan lain untuk skrining pasien.
Metode: Penelitian ini adalah penelitian potong lintang dengan metode consecutive sampling. Peneliti mengidentifikasi subjek POP dengan dan tanpa keluhan benjolan. Subjek yang bersedia ikut serta dalam penelitian ini menjalani pemeriksaan POP-Q, panjang genital hiatus (Gh) dan perineal body (Pb), dan pemeriksaan USG translabial 3D/4D. Data dianalisis menggunakan SPSS Statistics 20 dengan uji T tidak berpasangan untuk membandingkan rerata parameter luas area hiatus dan panjang anteroposterior levator ani. Selanjutnya dilakukan analisa ROC untuk mendapatkan nilai titik potong dengan estimasi sensitifitas dan spesifisitas terbaik untuk membedakan prolaps bergejala dan tidak bergejala benjolan. Hasil: Sebanyak 109 subjek ikut serta dalam penelitian ini. Terdapat perbedaan bermakna luas hiatus (28,9+5,59 vs 19,6+4,63, p < 0,05 saat valsalva, 15,2+4,08 vs 12,5+3,15, p <0,005 saat kontraksi) dan panjang anteroposterior levator ani (8,6+1,06 vs 6,8+1.13, p<0,05) antara kelompok dengan keluhan benjolan dan kelompok tanpa keluhan benjolan. Titik potong luas area hiatus dan panjang anteroposterior levator ani untuk membedakan subjek dengan keluhan benjolan dan tanpa keluhan benjolan adalah 25,1 cm2 [sensitifitas 84,6%, spesifisitas 92,9%, AUC 0,925 (0,864-0,986)] dan 7,75 cm [sensitifitas 87,2%, spesifisitas 77,1%, AUC 0,859 (0,787-0,932)].
Kesimpulan: Terdapat perbedaan bermakna luas hiatus dan panjang anteroposterior levator ani antara kelompok dengan keluhan benjolan dan tanpa keluhan benjolan. Titik potong luas hiatus 25,1 cm dan panjang anteroposterior 7,75 cm memiliki sensitifitas dan spesifisitas yang baik untuk membedakan kedua kelompok.

Introduction: Pelvic organ prolapse (POP) is defined as descent of the pelvic viscera (uterus, bladder, urethra, and rectum) from its normal position. Levator ani muscle is the largest component of pelvic floor that plays an important part in POP pathogenesis. Previous study showed that there was difference in levator hiatus area and anteroposterior length on every grade of POP. The diagnosis of POP can be established from POP-Q tool, however its use is still very limited within its subspecialist practice causing the need of a new screening tool.
Methods: This was a cross-sectional study with consecutive sampling method. We classified POP subject with bulge symptom and without bulge symptom. Subjects that were willing to participate in this study under underwent POP-Q examination and 3D/4D transperineal ultrasonography. Data were analyzed using SPSS Statistics 20 with student’s t-test to compare levator hiatus area and anteroposterior length mean between 2 group.
Results: A total of 109 subjects were included in this study. There was a significance difference in levator hiatus area (28.9+5.59 cm2 vs 19.6+4.63 cm2, p < 0/05 during valsalva maneuver, 15.2+4.08 cm2 vs 12.5+3.15 cm2, p <0.05 during contraction) and anteroposterior length (8.6+1.06 c, vs 6.8+1.13 cm, p<0,05) between group with bulge symptom and without bulge symptom. Levator hiatus area and anteroposterior length cutoff to differentiate between subject with and without bulge symtoms was respectively 25,1 cm2 [sensitivity 84,6%, specificity 92,9%, AUC 0,925 (0,864-0,986)] and 7,75 cm [sensitivity 87,2%, specificity 77,1%, AUC 0,859 (0,787-0,932)].
Conclusion: There was a significant difference in levator hiatus area and anteroposterior length between group with and without bulge symptom. Levator hiatus area cut off at 25,1 cm2 anteroposterior length cut off at 7.75 cm showed good sensitivity and specificity to differentiate between 2 group.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Anggrainy Dwifitriana Kouwagam
"Latar Belakang:
Prolaps Organ Panggul (POP) merupakan kondisi kompleks yang terjadi akibat defek pada struktur penyokong vagina. Kondisi ini dapat disebabkan oleh proses trauma pada otot penyokong levator ani yang menyebabkan melebarnya luas hiatus genital. Pelebaran hiatus genital ini disebut ballooning. Prevalensi POP berkisar antara 20-50%, dengan insidensi mencapai 1,5 – 1,8 per 1000 wanita per tahun dengan puncak usia 60 – 69 tahun. Kondisi POP memberi dampak terhadap kualitas hidup seorang wanita dan sering dikaitkan dengan gangguan berkemih, buang air besar hingga disfungsi seksual. Tatalaksana definitif dalam penanganan POP adalah tindakan pembedahan. Tindakan levatorplasty dapat dilakukan pada kasus penurunan kompartemen posterior, terutama pada pasien POP dengan hiatal ballooning. Tindakan ini bertujuan untuk mengurangi risiko prolaps berulang di masa mendatang. Pasien dengan rencana operasi POP di RS Cipto Mangunkusumo (RSCM) Jakarta yang disertai ballooning pada pemeriksaan USG pre-operatif dilakukan tambahan tindakan levatorplasty, namun belum ada penilaian pasca operasi mengenai perbaikan kondisi ballooning tersebut.
Objektif:
Penelitian ini bertujuan untuk mengetahui perbaikan ballooning sebelum dan setelah dilakukannya tindakan levatorplasty pada pasien dengan POP. Perbaikan yang dinilai berupa perbaikan luas dan panjang diameter anterioposterior hiatus levator, perbaikan panjang Gh + Pb, serta perubahan skor keluhan disfungsi dasar panggul sebelum dan sesudah tindakan. Penilaian dilakukan dengan menggunakan USG 3 dan 2 dimensi untuk hiatus levator, pemeriksaan klinis Pelvic Organ Prolapse Quantification System (POP-Q) untuk panjang Gh + Pb, serta kuisioner Pelvic Floor Distress Inventory-20 (PFDI-20) untuk penilaian keluhan klinis disfungsi dasar panggul.
Metode:
Studi analitik komparatif berpasangan dengan desain gabungan kohort retrospektif dan kohort prospektif yang dilakukan di Poliklinik Kebidanan dan Kandungan Divisi Uroginekologi dan Rekonstruksi Departemen Obstetri dan Ginekologi RSUPN dr. Cipto Mangunkusumo. Pengumpulan data retrospektif dilakukan dari Oktober 2021 hingga April 2022, dengan pengumpulan data prospektif untuk dilakukan tindakan levatorplasty dilakukan dari Oktober 2021 hingga Januari 2022. Sampel penelitian adalah wanita dengan POP dan ballooning yang dinilai dengan pemeriksaan USG Transperineal serta POP-Q, dan akan menjalani operasi levatorplasty.
Hasil:
Tingkat keberhasilan levatorplasty pada pasien POP dengan ballooning dilihat dari penurunan derajat ballooning berdasarkan kategori Lh max pada 28 pasien (87,5%), Ap hiatal pada 26 pasien (81,25%), dan panjang Gh + Pb pada 25 pasien (78,1%). Parameter PFDI yang diukur juga mengalami perbaikan dengan penurunan nilai median PFDI mencapai 31,2 (p = 0,009), serta penurunan pada nilai median sub-bagian POPDI-6 hingga 20,8 (p = 0,009), CRADI-6 hingga 6,2 (p = 0,096), dan UDI-6 hingga 10,4 (p = 0,360).
Kesimpulan:
Prosedur levatorplasty ditemukan dapat memperbaiki kondisi ballooning pada pasien POP yang dinilai dari perbaikan nilai luas dan panjang diameter anteroposterior hiatus levator, perbaikan klinis secara objektif (yang dinilai dengan pemeriksaan POP-Q) serta secara subjektif (yang dinilai dengan kuisioner PFDI-20). Hasil penelitian ini diharapkan mampu menjadi bukti untuk penerapan prosedur levatorplasty untuk dapat dilakukan pada pasien-pasien POP yang disertai dengan ballooning di tempat praktik klinis di semua penjuru Indonesia.

Background:
Pelvic Organ Prolapse (POP) is a complex condition resulting from defects in the supporting structures of the vagina. This condition can be caused by a traumatic process to the supporting muscles of the levator ani which causes the widening of the genital hiatus. This widening process is called ballooning. The prevalence of POP ranges from 20-50%, with an incidence reaching 1.5-1.8 per 1000 women each year with a peak age of 60-69 years. POP conditions may have an impact on a woman's quality of life and are often associated with urinary and defecation disorders, and also sexual dysfunction. The definitive treatment for POP is surgery. Levatorplasty can be performed in cases of posterior compartment descent, especially in POP patients with Hiatal ballooning. This action aims to reduce the risk of recurrent prolapse in the future. At Dr. Cipto Mangunkusumo Hospital (RSCM) Jakarta, patients with POP who are found with Hiatal ballooning during pre-operative ultrasound examination will be planned for an additional levatorplasty procedure. But there was no postoperative assessment regarding the improvement of the ballooning condition.
Objective:
This study aims to determine the improvement of ballooning after the levatorplasty procedure in patients with POP. The improvements assessed were the area and length of the anteroposterior diameter of the levator hiatus, the length of Gh + Pb, and complaints improvement for pelvic floor dysfunction. The assessment was done using 3- and 2-dimensional ultrasound for levator hiatus, clinical examination of the Pelvic Organ Prolapse Quantification System (POP-Q) for length Gh + Pb, and the Pelvic Floor Distress Inventory-20 (PFDI-20) questionnaire to assess clinical complaints of pelvic floor dysfunction.
Methods:
A paired comparative analytic study with a combined retrospective and prospective cohort design was carried out at the Obstetrics and Gynecology Outpatient Unit, Division of Urogynecology and Reconstruction, Department of Obstetrics and Gynecology, dr. Cipto Mangunkusumo Central General Hospital Jakarta. Retrospective data was collected from October 2021 to April 2022, with prospective data for levatorplasty performed from October 2021 to January 2022. The study sample was women with POP and ballooning who were assessed by transperineal ultrasound examination and POP-Q examination and will undergo levatorplasty procedure.
Result:
The success rate of levatorplasty in POP patients with ballooning was seen from the decrease in the degree of ballooning by the measurement of Lh max in 28 patients (87.5%), Ap hiatal in 26 patients (81.25%), and the length of Gh + Pb in 25 patients (78, 1%). The measured PFDI parameters also improved with a decrease in the median value of PFDI reaching 31.2 (p = 0.009), as well as a decrease in the median value of the POPDI-6 subsection to 20.8 (p = 0.009), CRADI-6 to 6.2 (p = 0.096), and UDI-6 to 10.4 (p = 0.360).
Conclusion:
The levatorplasty procedure is proven to repair the ballooning conditions in POP patients as assessed by improvements in the area and length of the anteroposterior diameter of the levator hiatus, clinical improvement objectively (as assessed by the POP-Q examination), and subjectively (as assessed by the PFDI-20 questionnaire). The results of this study are expected to be evidence for the application of the levatorplasty procedure to be performed on POP patients accompanied by ballooning in many clinical practices throughout Indonesia.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
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UI - Tesis Membership  Universitas Indonesia Library
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Raihan Fikri Ali Akbar
"Latar Belakang Prolaps organ panggul (POP) merupakan perubahan posisi organ-organ penyusun panggul dari posisi normal. Ballooning atau distensi otot levator ani dinilai menjadi penyebab POP. Penentuan balloning sejauh ini masih menggunakan USG 3D/4D yang tidak banyak ada di Indonesia. Diperlukan penelitian perbandingan ballooning dan non-ballooning dengan USG 2D untuk menentukan ballooning dengan panjang antero-posterior (AP) hiatus levator ani. Metode Digunakan metode deskriptif analitik menggunakan perbandingan rerata dengan desain penelitian potong lintang retrospektif dan pemilihan sampel penelitian secara konsekutif. Didapatkan sebanyak 72 subjek dengan 37 orang berada pada kelompok ballooning. Hasil Usia kelompok ballooning dan non-ballooning berada pada usia dewasa tua (60.35 ± 11.06 vs 56.54 ± 11.14 tahun, p=0.096), obesitas (26.73 ± 3.94 vs 24.53 ± 2.88 kg/m2, p=0.015), aktivitas berat (51.3% vs 65.7%, p=0.217), pekerjaan ibu rumah tangga (64.8% vs 65.7%, p=0.893), multiparitas (72.9% vs 60.0%, p=0.210), menopause (75.6% vs 74.2%, p=0.892), bayi lahir terberat ≥ 3500 gram (56.7% vs 45.7%, p=0.349), dan persalinan normal (83.7% vs 88.5%, p=0.420). Rerata anteroposterior ballooning lebih besar dibandingkan non-ballooning (7.09 ± 0.63 vs 5.56 ± 0.64 cm) dengan seluruh subjek ballooning memiliki panjang AP di atas 6 cm (<0.001). Kesimpulan Obesitas dan berat badan berhubungan dengan adanya ballooning pada pasien POP. Perbandingan AP hiatus levator ani menunjukkan perbedaan sehingga skrining ballooning berdasarkan panjang AP hiatus dapat dilakukan untuk membedakan kedua kelompok.

Introduction Pelvic organ prolapse (POP) is a change in the position of the organs that make up the pelvis from their normal position. Ballooning or distension of the levator ani muscle is considered to cause POP. This determination of ballooning still uses 3D/4D ultrasound, which is not widely available in Indonesia. Comparative research between ballooning and non-ballooning with 2D ultrasound is needed to determine the ballooning through anteroposterior (AP) length of the levator ani hiatus. Method The analytical descriptive method was used using mean comparisons with a retrospective cross-sectional research design and consecutive research sample selection. There were 72 subjects with 37 people in the ballooning group. Results The ages of the ballooning and non-ballooning groups were older adults (60.35 ± 11.06 vs 56.54 ± 11.14 years, p=0.096), obesity (26.73 ± 3.94 vs 24.53 ± 2.88 kg/m2, p=0.015), heavy activity (51.3% vs 65.7%, p=0.217), housewife work (64.8% vs 65.7%, p=0.893), multiparity (72.9% vs 60.0%, p=0.210), after menopause (75.6% vs 74.2%, p=0.892) , the heaviest baby born ≥ 3500 grams (56.7% vs 45.7%, p=0.349), and normal delivery (83.7% vs 88.5%, p=0.420). The mean anteroposterior ballooning was greater than non-ballooning (7.09 ± 0.63 vs 5.56 ± 0.64 cm) with all ballooning subjects having an AP length above 6 cm (<0.001). Conclusion Obesity and body weight are associated with ballooning in POP patients. Comparison of the AP hiatus of the levator ani shows differences so that ballooning screening based on the length of the AP hiatus can be performed to differentiate the two groups."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2023
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UI - Skripsi Membership  Universitas Indonesia Library
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Lestari Mustika Rini
"ABSTRAK
Latar Belakang: Avulsi levator ani merupakan lepasnya otot puborektalis dari insersinya pada dinding pelvis. Kejadian ini seringkali terjadi akibat trauma persalinan pervaginam dan dapat menyebabkan gejala uroginekologi beberapa tahun kemudian. Tujuan: Untuk mengetahui proporsi avulsi levator ani menggunakan ultrasonografi 3D/4D dan menentukan faktor-faktor persalinan pervaginam yang berkontribusi pada terjadinya avulsi levator ani diantara pasien dengan gejala prolaps organ panggul. Metode: Studi potong-lintang dilakukan pada pasien dengan gejala prolaps organ panggul di Poliklinik Uroginekologi RSUPN Cipto Mangunkusumo Jakarta. Secara retrospektif dan prospektif dilakukan pengumpulan data sejak Januari 2012 hingga April 2017 dengan pemeriksaan klinis menggunakan POP-Q dan ultrasonografi 3D/4D transperineal untuk menilai otot levator ani.Hasil: Dari total 127 pasien prolaps organ panggul yang dimasukkan sebagai subjek memiliki median usia 61 26-80 tahun, median paritas 3 0-13 dengan 2 pasien nuligravida dan 2 pasien menjalani persalinan hanya dengan seksio sesarea. Sebanyak 10 subjek 7.9 , IK95 3.1-12.6 terdeteksi adanya avulsi levator ani menggunakan USG 3D/4D transperineal. Diantara kelompok avulsi tersebut dilakukan analisis dengan mengeksklusi 4 pasien tanpa persalinan pervaginam. Dari total 123 pasien, median usia pertama melahirkan adalah 26 18-31 tahun, p=0.156; median jumlah persalinan pervaginam adalah paritas 3 1-9 , p=0.19; riwayat persalinan dengan forsep hanya terdapat 1 kasus 10 , p=0.081; riwayat persalinan dengan vakum 10 , p=0.35, dari total 5 kasus vakum; dan berat lahir bayi terbesar dengan median 3470 3100-3700 gram, p=0.752.Kesimpulan: Proporsi avulsi levator ani pada pasien prolaps organ panggul di Poliklinik RSUPN Dr. Cipto Mangunkusumo sebesar 7.9 . Faktor risko obstetri seperti usia pertama melahirkan, jumlah persalinan pervaginam, riwayat persalinan dengan forsep, riwayat persalinan dengan vakum dan berat lahir bayi terbesar tidak dapat disimpulkan hubungannya dengan terjadinya avulsi levator ani.

ABSTRACT
Background Avulsion of levator ani could arise from detachment of puborectalis muscle form its insertion on the pelvic sidewall. This manifest is a common consequence of vaginal childbirth trauma and could represent urogynecological symptoms many years later. Objective To estimate the proportion of levator ani avulsion using 3D or 4D ultrasound and determine the vaginal birth factors that contribute to levator ani avulsion among the symptomatics of pelvic organ prolapse women. Methods Cross sectional study was conducted among women with symptomatic pelvic organ prolapse in Urogynecology Clinic RSUPN Cipto Mangunkusumo Jakarta. Patients were retrospective and prospectively investigated from January 2012 until April 2017 by clinical examination using POP Q system and 3D 4D imaging of levator ani muscle.Results A total 127 women with pelvic organ prolapse were included in this study, median age was 61 26 80 years, median parity was 3 0 13 with 2 patients were nulligravid and 2 patients have giving birth by c section only. There were 10 cases 7.9, IK95 3.1 12.6 levator avulsion by transperineal 3D 4D US exam. In the group of levator avulsion, 4 cases without history vaginal birth were excluded. Of total 123 patients, first age delivery median was 26 18 31 years, p 0.156 vaginal birth parity median was 3 1 9, p 0.19 1 case forceps delivery 10, p 0.081 vacuum delivery 10, p 0.35, from total vacuum history was 5 cases and maximum birthweight median mas 3470 3100 3700 gram, p 0.752.Conclusion Proportion of levator avulsion in women with pelvic organ prolaps at RSUPN Dr. Cipto Mangunkusumo was 7.9 . First age delivery, vaginal birth parity, forceps delivery, vacuum delivery, dan maximum birth weight as obstetric factors cannot be concluded these association to levator avulsion."
2017
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UI - Tesis Membership  Universitas Indonesia Library
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Elisia
"ABSTRAK
Latar belakang: Tesis ini bertujuan untuk mengetahui insidens retensio urin
pasca rekonstruksi POP dan faktor-faktor yang berhubungan.Retensio urin
merupakan komplikasi akut tindakan rekonstruksi dan banyak dijumpai pada
prosedur operasi, termasuk operasi POP (POP). Untuk menghindari morbiditas
lebih lanjut, penelitian ini bertujuan untuk mengetahui insidens rertensio urin
pasca rekonstruksi POP faktor-faktor risiko yang berhubungan.
Metode: Penelitian ini adalah penelitian kohort prospektif yang dilaksanakan di
RS Cipto Mangunkusumo dan RS Fatmawati dengan mengikutsertakan wanita
yang hendak mengalami rekonstruksi POP dalam rentang waktu April 2013
hingga April 2015. Kriteria inklusi dan eksklusi subjek meliputi wanita dengan
POP derajat 2,3 dan 4 tanpa riwayat retensio urin sebelumnya, konsumsi obatobatan
yang
dapat menyebabkan retensio urin dan tanpa cedera kandung kemih.
Pasca rekonstruksi, subjek dilakukan pemasangan kateter urin selama 24 jam.
Kemudian, enam jam pasca pelesapan kateter, dilakukan pengukuran residu urin
pada kandung kemih. Retensio urin didefinisikan dengan didapatkannya residu
urin >100 ml.
Hasil: Dari 200 subjek, ditemukan 59 subjek (29,5%) mengalami retensio urin.
Tidak ada hubungan antara faktor risiko umur, Indeks Massa Tubuh (IMT),
derajat POP, derajat sistokel, kejadian infeksi saluran kemih, dan durasi operasi
terhadap retensio urin. Jenis prosedur total vagina hysterectomy + kolporafi
anterior + kolpoperineorafi + sacrospinous fixation dan durasi operasi > 130
menit berhubungan dengan retensio urin dengan RR 3,66 95% IK 2,91-4,60
p<0,001 dan 1,66 95%IK 1,07-2,59 p=0,02, berturut-turut
Kesimpulan: Insidens retensio urin cukup tinggi pasca rekonstruksi POP. Jenis
tindakan rekonstruksi tertentu dan semakin lamanya durasi rekonstruksi
berhubungan dengan kejadian retensio urin.ABSTRACT
Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
;Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
;Background: The objective of this study was to know the incidence of post
operativeurinaryretention after pelvic organ prolapse surgery and associated
factors.Post operative urinary retention (POUR) is considered as an acute
complication after a surgey in many operative procedures, including pelvic organ
prolpase (POP) surgery. To avoid further morbidity, this study aimed to know the
incidence of POUR after POP surgery and its risk factors.
Methods: This is a prospective cohort study conducted in Cipto Mangunkusumo
hospital and Fatmawati Hospital from April 2013 to April 2015. Subjects were
women who wanted to undergo POP surgery with two to four degree of POP.
Subjects with history of urinary retention, drugs consumption that tend to cause
urinary retention or bladder unjury were excluded. After the reconstruction,
urinary catheter was placed for 24 hours. Then, after six hours, catheter was
removed and residual urine was measured. Urinary retention was defined as
residual urine more than 100 ml.
Results: Of 200 subjects recruited, 59 (29.5%) had POUR. There were no
association between age, body mass index, degree of uterine POPe, degree of
cystocele, urinary tract infectionand POUR. Duration of surgery > 130 minute and
Total vagina hysterectomy +anterior colporraphy + colpoperineorraphy +
sacrospinous fixation procedure and duration of surgery > 130 minute were
associated with POUR (RR 3.66, 2.91-4.60 95% CI, p<0.001 and 1.66 , 072.5995%CI,
p=0.02;
respectively)
Conclusion: POUR incidence after POP surgery was quite high. Type of the
procedure and duration of surgery were associated with POUR.
"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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