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"This book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children. "

"Over the past 40 years the field of molecular simulations has evolved from picosecond studies of isolated macromolecules in vacuum to studies of complex, chemically heterogeneous biological systems consisting of millions of atoms, with the simulation time scales spanning up to milliseconds. In Biomolecular Simulations: Methods and Protocols, expert researchers illustrate many of the methods commonly used in molecular modelling of biological systems, including methods for electronic structure calculations, classical molecular dynamics simulations and coarse-grained techniques. A selection of advanced techniques and recent methodological developments, which rarely find coverage in traditional textbooks, is also introduced. Written in the highly successful Methods in Molecular Biology series format, chapters include general introductions to well-established computational methodologies, applications to real-world biological systems, as well as practical tips and general protocols on carrying out biomolecular simulations. Special emphasis is placed on simulations of proteins, lipids, nucleic acids, and carbohydrates. Authoritative and practical, Biomolecular Simulations: Methods and Protocols seeks to aid scientists in further simulation studies of biological systems."

"Keberhasilan pembangunan kesehatan sangat dipengaruhi oleh tersedianya tenaga kesehatan yang bermutu dalam jumlah dan jenis yang sesuai dengan kebutuhan program. Setelah pemerintah memberlakukan zero growth, kebijaksanaan ini memperbesar kesenjangan di dalam pemenuhan kebutuhan tenaga medis bagi daerah terpencil dan sangat terpencil, terutama untuk Indonesia bagian Timur. Untuk menjamin tersedianya tenaga kesehatan dalam jumlah yang cukup untuk memenuhi kebutuhan program, maka Departemen Kesehatan melalui Keputusan Presiden No. 37 tahun 1991, mengambil kebijaksanaan untuk mengangkat Dokter sebagai Pegawai Tidak Tetap (Dokter PTT ), selama masa bakti. Walaupun Departemen Kesehatan telah menempatkan sekitar 20.682 Dokter PTT diseluruh Indonesia, pada kenyataan menunjukkan bahwa sampai saat ini masih dijumpai berbagai masalah dalam hal perencanaan, pengadaan dan pendayagunaannya. Bertitik tolak dari permasalahan tersebut, peneliti mencoba untuk memberi masukan dengan membuat Rancangan Pengembangan Sistem Informasi Manajemen Dokter PTT, untuk mendukung penanganan manajemen Dokter PTT yang berbasis komputer. Diharapkan dengan sistem berbasis komputer ini data / informasi Dokter PTT dapat akurat di setiap jenjang administrasi. Ruang lingkup yang diteliti mengenai SIM-Dokter PTT mencakup identifikasi informasi, pengumpulan data. Penelitian dilakukan dengan observasi dan wawancara mendalam, melalui pengumpulan data sekunder dan observasi lapangan . Temuan yang paling menonjol adalah: prosedur dan mekanisme pengumpulan data belum ada yang baku, instrumen / alat pengumpulan data belum standar, tidak adanya laporan dari Kabupaten ke Propinsi, kemudian dari Propinsi ke Pusat, serta tidak terdokumentasinya dokumen / data dengan baik. Disarankan agar dilakukan upaya-upaya untuk terlaksananya koordinasi yang baik antara unit pengelola manajemen Dokter PTT yang terkait, baik lintas program maupun lintas sektor. Dengan demikian diharapkan akan diperoleh kesamaan persepsi tentang SIM Dokter PTT, khususnya mengenai manfaat bagi penanganan manajemen Dokter PTT di jajaran Departemen Kesehatan RI.

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Designing of Management Information System Referral Development for - Medical Doctor as Temporary Public ServantThe success of health development program is very much determined by the availability of the qualified medical workers in its numbers and types of working specialization according to the needs of the program. After the Zero growth was being implemented by the government, this policy has widen the gap in fulfilling the needs of medical workers for the isolated places and the very isolated, one, especially for the region of the Eastern part of Indonesia. To assure the availability of the medical workers in its proper numbers for the needs of the program, the Department of Health through its official regulation of 1991 NO. 37 - Keppres NO. 37 th. 1991 - Had released the policy to appoint the Doctor as Temporary Public Servant due to their assignment period of working. Although the Department of Health has assigned about 20.682 of Medical Doctors as Temporary Public Servant all over the country (Indonesia) but in reality it shows that until now there are still many problems about the planning, providing, and the using of their works effectively. Based on that problem, the writer is trying to give some informative solution on designing of Management Information System Referral Development for the Medical Doctor as Non-Permanent Public Servant in order to support the working on management of the medical doctor as non-permanent public servant which is mainly relied on computer. Through this system that focused more on computer, it can serve more accurate data of information of M.D. as T.P.S in every level of administration. The scope of the study on this topic (M.D. as T.P.S) includes the identification and observation, through the collection of the secondary data and field observation. Findings pointed out mainly that the procedure and the mechanism of the data collection have not been set properly, while the instrument/the tools of data collection has not been standardized, and there has not been report from the District to the Province then from the Province to the Central, also the document / data has not been documented well. It is suggested to have some good coordination among the operator units of management of M.D. as T.P. S concerned, either through interprogram or inter sectoral. In that way, it will have the same perception on. particularly about."

"Sistem Informasi Medical Check Up merupakan suatu pengelolaan informasi di Unit Medical Check Up. Masih terdapatnya masalah yang dihadapi dalam penyelenggaraan kegiatan di unit ini dikarenakan belum memilikinya aplikasi khusus Medical Check Up yang dibutuhkan terutama oleh dokter untuk mendukung proses entry hasil pemeriksaan pasien yang dapat mendukung kegiatan pelaporan yang lebih akurat. Namun pengembangan sistem informasi ini membutuhkan waktu, tenaga, pikiran serta biaya, sehingga dibutuhkan suatu analisa terhadap persiapan pembangunan saat ini agar pelaksanaan kedepannya dapat lebih efektif serta efisien. Penelitian ini bertujuan agar terbentuk suatu Sistem Informasi Medical Check Up yang memiliki efisiensi dan efektifitas dalam penggunaannya yang digambarkan berupa desain prototype sistem informasi. Metode yang digunakan dalam penelitian ini adalah dengan menggunakan metode kepustakaan, wawancara mendalam serta observasi dalam mengumpulkan data. Hasil penelitian ini menunjukkan bahwa Unit Medical Check Up ini membutuhkan suatu Sistem Informasi Medical Check Up yang sesuai dengan kebutuhan saat ini dan sesuai dengan perkembangan zaman."

"In this book, present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed, labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics."

"Skripsi ini ditujukan untuk merancang Penguat Derau Rendah hibrid yang bekerja pada frekuensi 13 MHz untuk aplikasi implan medis dengan memodifikasi topologi current reuse. Induktor yang terhubung dengan terminal source pada sisi common gate di topologi konvensional current reuse digantikan oleh resistor, sehingga rangkaian yang diusulkan dapat bekerja pada frekuensi rendah secara optimal. Analisa matematis pada impedansi masukan dan penguatan telah dilakukan untuk mengoptimasi setiap nilai komponen elektronika dalam rangkaian. Berdasarkan hasil simulasi, didapat rangkaian Penguat Derau Rendah berpenguatan 20,85 dB dengan noise figure 15,78 dB yang bekerja pada frekuensi 13 MHz. Konsumsi daya yang dibutuhkan oleh rangkaian ini sebesar 1,644 mW. Desain Penguat Derau Rendah ini telah dirancang pada PCB (printed circuit board) dan telah dilakukan pengujian parameter-S. Akan tetapi hasil pengujian yang dilakukan tidak sesuai dengan simulasi karena MOSFET yang digunakan tidak dapat bekerja secara optimal.

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This thesis is intended to design a hybrid Low Noise Amplifier that work at 13 MHz by modifying the current reuse topology. The inductor connected to the source terminal on the common gate side in the conventional current reuse topology is replaced by resistor, so the proposed circuit can work at low frequency optimally. Mathematical analysis of input impedance and gain has been carried out to optimize each value of electronic components in the circuit. Based on the simulation results, obtained gain of Low Noise Amplifiers is 20.85 dB with a noise figure 15.78 dB that works at 13 MHz. The power consumption required by this circuit is 1.644 mW. This Low Noise Amplifier design has been designed on a PCB (printed circuit board) and has been tested for S-parameters. However, the results of the tests performed did not match the simulation because the MOSFETs used could not work optimally."