Hasil Pencarian  ::  Simpan CSV :: Kembali

"Latar Belakang: Kanker serviks menduduki peringkat ke tiga di seluruh dunia sebagaipenyebab kematian perempuan dan merupakan penyebab kematian utama perempuan dinegara berkembang. Diperlukan evaluasi kesintasan berkala yang secara tidak langsungmenjadi cermin tatalaksana.Tujuan: Mengetahui kesintasan pasien kanker serviks di RSCM.Metode: Penelitian ini menggunakan desain kohort retrospektif terhadap data rekammedis pasien kanker serviks pada tahun 2012-2014 dengan metode total populationsampling. Analisis data dilakukan menggunakan kurva Kaplan Meier, uji Log Rank dan Regresi Cox untuk mencari kemaknaan hubungan antarvariabel.Hasil: Terdapat 1.303 subjek penelitian dengan angka kesintasan kanker serviks hingga tahun ke-5 sebesar 76%, 66%, 60%, 43% dan 36% dengan median kesintasan sebesar 1355 hari secara keseluruhan. Terdapat perbedaan hazard bermakna pada variabel stadium kanker (p<0,001). Analisis regresi cox menunjukkan faktor yang berpengaruh terhadap kesintasan adalah stadium kanker. Kesimpulan: Kesintasan 5 tahun kanker serviks di RSCM tahun 2012-2014 sebesar 36%.

---

Background: Cervical cancer is ranked third as female cause of death worldwide and isthe leading cause of death of women in developing countries. A periodic survivalevaluation is required that implies the treatment implicitly.Objective: To know the survival rate of cervical cancer patients at CiptoMangunkusumo Hospital.Methods: This retrospective cohort study used medical records data of cervical cancerpatients in 2012- 2014 using total population sampling method. Data analysis was doneusing Kaplan Meier curve, Rank Log test and Cox Regression to find the associationbetween variables.Results: There were 1.303 subjects with overall kesintasan rates of cervical cancer up tothe fifth year of 76, 66, 60, 43 dan 36 with a median survival 1355 days. There were significant hazard differences in cancer stage variables (p <0.001). Cox regression analysis showed that factors affecting survival were cancer stage. Conclusion: The 5-year kesintasan rate of cervical cancer at Cipto Mangunkusumo hospital in 2012-2014 is 36%."

"Tesis ini bertujuan Untuk mengetahui pengaruh merokok pada kesintasan penderita kanker serviks stadium lanjut di Rumah Sakit Umum Ciptomangunkusumo. Penelitian ini bersifat kohort retrospektif. Hasil penelitian didapatkan tingkat merokok oleh pasien dan atau suami pasien tidak signifikan secara statistik sebagai faktor prognosis terhadap pasien kanker serviks stadium lanjut di RSCM. Kesintasan 5 tahun pasien kanker serviks stadium lanjut dalam studi kami adalah 22 bulan (4-58 bulan) dengan persentase kesintasan 22,6%. Dengan analisis multivariat didapatkan bahwa hanya ukuran tumor dan stadium kanker bermakna secara statistik terhadap kesintasan.

---

This thesis aims to determine the effect of smoking on the survival rate of advanced stage cervical cancer patients in the Ciptomangunkusumo General Hospital. This study is a retrospective cohort. The results showed that smoking levels by the patient or the patient's husband was not statistically significant as a prognostic factor for patients with advanced cervical cancer in RSCM. 5-year survival of patients with advanced cervical cancer in our study was 22 months (4-58 months) with a percentage of 22.6% survival rate. By multivariate analysis. it was only tumor size and stage of the cancer that statistically significant to the survival rate."

"Latar belakang: Kanker serviks adalah salah satu keganasan ginekologi yang paling umum di dunia, termasuk Indonesia. Kanker serviks menyebabkan 18,279  kematian per tahun di Indonesia dan menyebabkan beban fisik, mental, dan sosial ekonomi bagi pasien dan keluarga. National Comprehensive Cancer Network (NCCN) telah menerbitkan pedoman pengobatan pasien kanker serviks yang  selalu diperbarui (up-to-date) dengan tujuan agar pengobatan lebih terkoordinasi  dan efisien. Pedoman ini telah diadaptasi oleh Indonesia, namun keefektifannya belum dipertanyakan.Metode: Kami melakukan peninjauan sistematis sesuai dengan PRISMA  statement untuk menilai efektivitas kesesuaian pedoman. Pencarian dengan  strategi pada database PubMed, ProQuest, Scopus, dan Wiley menghasilkan tiga studi yang memenuhi semua kriteria, selanjutnya dinilai dengan skala NewcastleOttawa dan secara kualitatif.Hasil: Kami menemukan bahwa proporsi kesesuaian pedoman mulai dari 42% hingga 47% dengan faktor-faktor yang mendasarinya seperti jarak ke fasilitas  kesehatan, stadium kanker serviks, penggunaan asuransi, ras, dan faktor sosial  ekonomi lainnya. Kami juga menemukan bahwa terdapat kesintasan hidup lima tahun yang lebih baik dari pasien kanker serviks pada kelompok yang sesuai dibandingkan kelompok yang tidak sesuai. Selain itu, ditemukan lokalisasi dan  kualitas hidup yang lebih baik dari pasien kanker serviks pada kelompok yang sesuai terhadap pedoman. Ketiga studi menggunakan pedoman NCCN sebagai kontrol, sehingga studi-studi tersebut dapat digunakan.Kesimpulan: Tindakan harus diambil dengan tindakan multidisiplin untuk memastikan bahwa setiap pasien kanker serviks memiliki akses pengobatan yang sesuai terhadap pedoman.

---

Background: Cervical cancer is the one of the most common gynecology malignancy in the world, including Indonesia. It has accounted for 18,279 deaths per year in Indonesia and caused physical, mental, and socioeconomic burden for patients and caregivers. National Comprehensive Cancer Network (NCCN) has published up-to-date guideline in-order to make more coordinated and efficient treatment for cervical cancer patients. This guideline has been adapted by Indonesia, however its effectivity is yet to be questioned,

Methods: we conducted systematic review according to PRISMA statement to assess effectivity of guideline adherence. Searching with strategy on PubMed, ProQuest, Scopus, and Wiley databases resulted in three studies that met all criteria, thus assessed further with Newcastle-Ottawa scale and assessed qualitatively.

Results: We found that proportion of guideline adherence ranging from 42% to 47% with factors underlying such as distance to health facility, cervical cancer stage, subscription to insurance, race, and other socioeconomic traits. We also found that there is better five-year survival of cervical cancer patients on guideline-adherent group versus non-guideline-adherent group. In addition, there is better cancer localization and life quality of patient in guideline-adherent group. All three studies were using NCCN guideline as control, thus applicable.

Conclusion: Actions should be taken by multidisciplinary action to ensure that every cervical cancer patient has access to guideline-adherent therapy."

"ABSTRAKKanker serviks merupakan keganasan keempat tersering pada perempuan di dunia. Berdasarkan prognosis dan terapi, kanker serviks dibagi menjadi dua kelompok, yaitu stadium awal dan stadium lanjut. Tata laksana standar kanker serviks stadium awal adalah histerektomi radikal dan limfadenektomi. Keterlibatan kelenjar limfe merupakan salah satu faktor yang memengaruhi kesintasan pasien kanker serviks.Penelitian ini bertujuan untuk mengetahui apakah kelenjar limfe dapat dijadikan prediktor kesintasan. Penelitian ini menggunakan desain penelitian kohort retrospektif yang dilakukan di RSUPN dr. Cipto Mangunkusumo pada bulan Agustus 2015 sampai Agustus 2016.Subjek penelitian adalah pasien kanker serviks stadium awal yang dilakukan histerektomi radikal dan limfadenektomi dalam kurun waktu Januari 2011 sampai Desember 2013. Variabel yang diteliti adalah stadium tumor, ukuran tumor, histopatologi, diferensiasi tumor, invasi stroma, invasi limfovaskular, KGB pelvis, batas sayatan, dan invasi parametrium yang dihubungkan dengan kesintasan pasien. Data diolah menggunakan SPSS versi 20 dan dianalisis dengan uji chi square, uji regresi cox metode stepwise, dan Kaplan Meier. Pada penelitian ini diperoleh 123 pasien kanker serviks yang dilakukan histerektomi radikal dan limfadenektomi namun data yang dianalisis adalah 50 pasien yang memenuhi kriteri inklusi dan lolos kriteria eksklusi.Hasilnya, stadium tumor, ukuran tumor, histopatologi, diferensiasi tumor, invasi limfovaskular, KGB pelvis, batas sayatan, dan invasi parametrium tidak berhubungan dengan kesintasan namun invasi stroma dan terapi radiasi berhubungan dengan kesintasan. Jumlah KGB yang diekstraksi tidak berpengaruh terhadap kesintasan namun subjek dengan invasi stroma <2/3 bagian memiliki kesintasan lebih baik. Terapi radiasi juga memberikan kesintasan lebih baik. Perlu dilakukan penelitian lebih lanjut untuk mengetahui faktor prognostik lain pada pasien kanker serviks stadium awal seperti ekspresi faktor-faktor stem cells (SOX4, NANOG dan OCT4).

---

ABSTRACTCervical cancer is the fourth most common cancer in women in the world. Based on the prognosis and therapy, cervical cancer is divided into two groups, which are the early and advanced stages. The standard management of early-stage cervical cancer is radical hysterectomy and lymphadenectomy. The involvement of lymph nodes is one of the factors that affect the survival of cervical cancer patients.This study aims to determine whether lymph nodes can be used as predictors of survival. This study used a retrospective cohort study design conducted at RSUPN Dr. Cipto Mangunkusumo in August 2015 until August 2016.The research subjects were early-stage cervical cancer patients who performed radical hysterectomy and lymphadenectomy in the period January 2011 to December 2013. Variables studied were tumor stage, tumor size, histopathology, tumor differentiation, stromal invasion, lymph-vascular invasion, pelvic lymph nodes, incision border, and parametric invasion associated with patient survival. Data was processed using SPSS version 20 and analyzed by chi square test, cox regression test stepwise method, and Kaplan Meier. In this study 123 patients with cervical cancer were obtained for radical hysterectomy and lymphadenectomy but the data analyzed were 50 patients who fulfilled the inclusion criteria and passed the exclusion criteria.As a result, tumor stage, tumor size, histopathology, tumor differentiation, lymph-vascular invasion, pelvic lymph nodes, incision border, and parametrial invasion were not associated with survival but stromal invasion and radiation therapy were associated to survival. The number of extracted lymph node did not affect survival but subjects with stromal invasion <2/3 of parts had better survival. Radiation therapy also provides better survival. Further research is needed to find out other prognostic factors in early stage cervical cancer patients such as expression of factor stem cells (SOX4, NANOG and OCT4)."

"Kanker leher rahim merupakan masalah kesehatan perempuan di Indonesia, sehubungan dengan angka kejadian dan angka kematian yang tinggi. Saat ini di dunia diperkirakan lebih dari 1 juta perempuan menderita kanker serviks, dan terdapat 500.000 kasus baru pertahun, dengan angka kematian 260.000. di Indonesia terdapat 100 kasus kanker leher rahim per 100.000 penduduk, dengan angka kematian 20 perhari (Nuranna, Laila et all, 2008). Tidak melakukan deteksi dini kanker leher rahim secara teratur dan tepat waktu merupakan faktor terbesar terjangkitnya kanker leher rahim. Deteksi dini kanker leher rahim metode IVA merupakan alternatif pemeriksaan yang berbiaya rendah yang dianjurkan untuk fasilitas dengan sumber daya terbatas. Puskesmas Prembun sebagai puskesmas percontohan pelayanan deteksi dini knker leher rahim metode IVA cakupannya terendah diantara puskesmas percontohan di wilayah dinas kesehatan kabupaten Kebumen, yaitu 46%. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengn perilaku wanita usia subur dalam deteksi dini kanker leher rahim metode IVA di wilayah Puskesmas Prembun Kabupaten Kebumen tahun 2012. Penelitian dilakukan di wilayah Puskesmas Prembun pada bulan Maret sampai dengan Mei 2012 terhadap 212 wanita usia 30 sampai dengan 50 tahun yang sudah menikah/melakukan hubungan seksual. Menggunakan metode penelitian kuantitatif dengan pendekatan studi cross sectional, dianalisa secara deskriptif dan bivariat. Hasil penelitian menunjukkan ada hubungan yang bermakna antara perilaku wanita usia subur dalam deteksi dini kanker leher rahim metode IVA dengan pengetahuan, sikap, keterjangkauan jarak, keterpaparan informasi/media massa, dukungan suami, dukungan petugas kesehatan dan dukungan kader kesehatan.

---

Cervical cancer is women?s health issues in Indonesia, with respect to the incidence and high mortality. Currently ini the world estimated at than 1 miilion women suffer from cervical cancer, and there are 500.000 new cases per year, with 260.000 death. In Indonesia there 100 cases of cervical cancer per 100.000 population, with 20 deaths per day (Nuranna, Laila et all, 2008). No early detection of cervical cancer regularly and on time is the biggest factor of cancer of the cervix. Early detection of cervical cancer IVA is an alternative method of lowcost examinations are recommended for facilities with limited resources. Prembun health centers as service centers pilot project method of early detection of cervical kanker IVA lowest coverage among health centers in the pilot project Kebumen district health department, which is 46%.

This study aims to determine the factors that deals with the behavior of women of childbearing age in the early detection of cervical cancer in the health center IVA method Prembun Kebumen 2012. The study was conducted at the health center Prembun in March until May 2012 on 212 women aged 30 to 50 years who are married / having sex. Using quantitative research method to study cross-sectional approach, the descriptive and bivariate analysis. The results showed no significant association between the behavior of women of childbearing age in the early detection of cervical cancer IVA method with the knowledge, attitudes, affordability range, exposure information / mass media, husband support, support for health workers and support health cadres."

"Salah satu dampak dari tindakan sinar dalam atau brakiterapi pada pengobatan kanker serviks adalah adanya disfungsi seksual. Penelitian ini bertujuan untuk mengidentifikasi gambaran indeks fungsi seksual pada klien kanker serviks. Desain penelitian menggunakan desain bersifat deskritif korelasi dengan menghubungkan masing-masing karakteristiknya. Dengan besar n = 50, menggunakan kuesioner indeks fungsi seksual yang terdiri dari 19 item pertanyaan dengan 6 domain di dalamnya. Analisis data dengan univariat dan bivariat dengan Uji T independen dan uji ANOVA. Hasil penelitian diperoleh gambaran indeks fungsi seksual yang rendah dan hubungan yang bermakna antara hubungan seksual setelah brakiterapi dan frekuensi dalam melakukan hubungan dengan indeks fungsi seksual total. Disarankan perawat dapat memberikan pendidikan kesehatan tentang seksualitas dengan benar agar klien memperoleh informasi secara maksimal.

---

One of impacts in internal radiotherapy or brachytherapy for cervical cancer treatment that has dysfunction of sexual. This study aims to Description of index sexual function for client‟s that has cervical cancer. Method of research that use of descriptively method which correlate in each of characteristic. the number of samples are 50 (n = 50), use of questionnaire about sexual function index that consisting of the 19 item of question by six domains. Analyzing of data by univariat and bivariat with independent test of "T" and test of ANOVA.

Determining of result is description of sexual function index in low and has good correlation between sexual intercourse after brachytherapy treatment and frequency of intercourse with sexual function index totally. Hopefully, the nurses can provide healthy education about sexuality correctly so that the clients can determine the information maximally."

"Tujuan : Untuk mengetahui pengaruh kadar hemoglobin, kadar hematokrit dan transfusi selama radiasi terhadap respon tumor dan kesintasan pada pasien kanker serviks stadium lanjut lokal (FIGO IIB-IIIB) yang menjalani terapi radiasi. Metode : Dilakukan studi kohort retrospektif terhadap pasien kanker serviks stadium IIB-IIIB yang memenuhi kriteria inklusi-eksklusi, yang berobat di Departemen Radioterapi RSCM periode Januari 2007 - Desember 2011, dianalisa dan dibandingkan respon tumor dan kesintasan antara kadar hemoglobin <11g/dL dengan ≥11g/dL, kadar hematokrit ≤35% dengan >35%, pasien yang ditransfusi dan tidak ditransfusi selama radiasi. Hasil : Respon tumor komplit pada kadar Hb sebelum radiasi <11g/dL dibandingkan dengan ≥11g/dL adalah 77,1% vs 70,2% p=0,34 ; kesintasan 3 tahun 84% vs 75% p=0,42. Respon tumor komplit pada kadar Hb selama radiasi <11g/dL dibandingkan dengan ≥11g/dL adalah 81,3% vs 67,9% p= 0,049 ; kesintasan 3 tahun 82% vs 79% p=0,05. Respon tumor komplit pada kadar Ht sebelum radiasi ≤35% dibandingkan dengan >35% adalah 71,7% vs 75,8% p=0,65 ; kesintasan 3 tahun 86% vs 78% p>0,05. Respon tumor komplit pada kadar Ht selama radiasi ≤35% dibandingkan dengan >35% adalah 72,7% vs 72,7% p=1,00 ; kesintasan 3 tahun 78% vs 87% p=>0,05. Kesintasan 3 tahun pada pasien yang ditransfusi dibandingkan dengan yang tidak ditransfusi 80% vs 84% p=0,95. Kesimpulan : Penelitian ini menunjukkan perbedaan yang bemakna pada pengaruh kadar hemoglobin rerata selama radiasi terhadap respon tumor dan kesintasan, pengaruh kadar hematokrit sebelum dan rerata selama radiasi terhadap respon tumor dan kesintasan.

---

Aim : To determine the effect of hemoglobin level, hematocrit level and transfusion during radiation on tumor response and survival rate in patients with locally advanced cervical cancer (FIGO IIB-IIIB) who underwent radiation therapy.

Methods : A retrospective cohort study has done on cervical cancer patients stage IIB-IIIB who met the inclusion-exclusion criteria, which is treated in the Department of Radiotherapy RSCM period January 2007 - December 2011, were analyzed and compared to tumor response and survival rate between hemoglobin level <11g / dL with ≥11g / dL, hematocrit level ≤35% to> 35%, patients with blood transfused or not during radiation.

Results : Complete tumor response in Hb levels before radiation <11g / dL compared with ≥11g / dL was 77.1% vs. 70.2% p = 0.34; 3-year survival rate 84% vs. 75% p = 0.42. Complete tumor response in hemoglobin levels during radiation <11g / dL compared with ≥11g / dL was 81.3% vs. 67.9% p = 0.049; 3-year survival rate 82% vs. 79% p = 0.05. Complete tumor response in hematocrit levels before radiation ≤35% compared to> 35% was 71.7% vs. 75.8% p = 0.65; 3-year survival rate 86% vs. 78% p> 0.05. Complete tumor response in hematocrit levels during radiation ≤35% compared to> 35% was 72.7% vs. 72.7% p = 1.00; 3-year survival rate 78% vs. 87% p => 0.05. 3-year survival rate in patients who were not transfused transfused compared with 80% vs. 84% p = 0.95.

Conclusions : This study shows that differences in the influence of mean hemoglobin levels during radiation on tumor response and survival rate, the influence of mean hematocrit levels before and during radiation on tumor response and survival rate."

"Kanker serviks di Indonesia berdasarkan keganasan pada jenis kelamin wanita, menempati urutan ke 2 dengan prevalensi sebesar 14,4 dan angka mortalitas sebesar 10,3. Dari sisi pembiayaan, pengobatan kanker menempati urutan kedua besar anggaran yang di keluarkan oleh BPJS Kesehatan. Data registrasi kanker sangat dibutuhkan untuk evaluasi dan membuat kebijakan yang tepat guna di rumah sakit dalam rangka meningkatkan kualitas pelayanan kanker. Hospital Based Cancer Registry HBCR merupakan suatu sistem registrasi kanker yang dilakukan di rumah sakit yang dapat menyediakan informasi mengenai informasi umum dari pasien kanker, pengobatan serta hasil dari pengobatan. Penelitian ini dilakukan untuk memperoleh profil kanker serviks di RSCM tahun 2013 berdasarkan data hospital based cancer registry. Penelitian dilakukan dengan mengekstraksi data epidemiologi dan data tumor serviks dari HBCR RSCM tahun 2013 yang kemudian dilakukan analisa deskriptif. Dari hasil penelitian didapatkan bahwa kanker serviks menempati urutan kedua terbanyak dari seluruh keganasan di RSCM 12 ,n= 678, dengan domisili sebagian besar berasal dari luar DKI Jakarta 52,8, n = 358. Usia rata-rata terjadinya kanker serviks adalah 49,48 tahun, tersering terjadi pada rentang usia 45-49 tahun. Dari sisi histopatologi, karsinoma sel skuamosa merupakan jenis histopatologi pada kanker serviks yang paling banyak dijumpai 74,2, n = 447. Tindakan operasi merupakan jenis tindakan yang paling banyak dilakukan pada kanker serviks stadium dini 83,3, n=25, sedangkan tindakan radiasi paling banyak dilakukan pada kanker serviks stadium lokal lanjut 79,9, n=273 .

---

Cervical cancer ranks at the second place based on the malignancy among female sex in Indonesia with a prevalence of 14.4 and a mortality rate of 10.3. From a financial perspective, the treatment of cancer ranks second big budget expended by the Indonesian national health insurance. Cancer registration data are needed to evaluate and make appropriate policy in hospitals in order to improve the quality of cancer services. Hospital Based Cancer Registry HBCR is a system of cancer registration in a hospital that can provide information about the general information of cancer patients, treatment, and outcome of treatment. This study was conducted to obtain the profile of cervical cancer in the RSCM in 2013 based on data from RSCM hospital based cancer registry. The study was conducted by extracting the epidemiological data and cervical tumor data from HBCR RSCM in 2013 which was then analyzed descriptively.

The result showed that cervical cancer ranks at the second place from all the malignancy at RSCM 12, n 678, with domicile mostly come from outside Jakarta 52.8, n 358. The average age of cervical cancer was 49.48 years, the most common occurs in the age range 45 49 years. In terms of histopathology, squamous cell carcinoma is the most prevalence type of histopathology of cervical cancer 74.2, n 447. The surgery is a type of action that done for early stage cervical cancer 83,3, n 25, whereas the action of radiation are mostly done in locally advanced cervical cancer 79,9, n 273."

"Kanker serviks diketahui menjadi kanker yang paling sering dialami oleh perempuan di dunia, termasuk di Indonesia. Kejadian kanker serviks dipengaruhi oleh multifaktor. Penelitian ini bertujuan untuk mengidentifikasi faktor berhubungan dengan kejadian kanker serviks. Rancangan penelitian yang digunakan yakni deskriptif korelatif dengan pendekatan potong lintang. Sebanyak 80 responden dipilih dengan menggunakan teknik consecutive sampling. Hasil analisis penelitian menunjukkan bahwa tidak ada hubungan signifikan antara perilaku seksual, perilaku merawat kebersihan alat kelamin (p=0,242; α=0,05), pengetahuan kanker serviks (p=0,252; α=0,05), dan riwayat kontrasepsi terhadap kejadian kanker serviks. Hasil penelitian menyarankan diperlukannya pembahasan/penelitian dengan studi kohort lebih lanjut mengenai hubungan faktor risiko kanker serviks terhadap kejadian kanker serviks.

---

Cervical cancer is one of the most common cancer happened by women in the world, included Indonesia. The cause of cervical cancer could be multifactorial. This study aim is to find in association risk factor of cervical cancer with cervical cancer incidence. Cross-sectional study was used in this study. Study sample included 80 sample as respondents which were selected by consecutive sampling technique.

The result showed that no significant relationship was found between sexual behavior, personal hygiene practice (p=0,242; α=0,05), history of contraception use, and knowledge of cervical cancer (p=0,252; α=0,05). Our findings suggest a need for using cohort study to discussion later about association cervical cancer risk factor and HPV infection."

"ABSTRAK Latar belakang. Infeksi human papillomavirus (HPV) pada genital laki-laki selain dapatmenyebabkan kutil kelamin dan kanker penis juga meningkatkan risiko infeksi HPV padapasangan. Walaupun saat ini telah terdapat banyak penelitian mengenai peran HPV risikotinggi terhadap karsinogenesis serviks dan semakin jelas peran laki-laki sebagai vektor virusHPV, namun pemeriksaan HPV pada laki-laki belum rutin dilakukan. Penelitian ini bertujuanmengetahui proporsi kepositivan, variasi genotipe HPV pada suami pasien kanker serviksserta kesamaan genotipe HPV antara suami pasien kanker serviks yang HPV positif denganpasien kanker serviks di RSUPN Dr Cipto Mangunkusumo. Metode. Penelitian potonglintang. Pemilihan SP dilakukan secara berurutan (consecutive sampling). Sampel diambildengan menggunakan kertas amplas dan dacron swab. Pada spesimen dilakukan pemeriksaanmenggunakan HPV express matrix Kalgen®. Hasil. Sebanyak 47 SP dilibatkan dalampenelitian ini, dengan rerata usia 50,7+10,6 tahun. Dari analisis spesimen diidentifikasi HPVgenital pada 9 (19%) SP, terdiri atas genotipe risiko rendah (3 SP) dan risiko tinggi (6 SP).Genotipe HPV yang ditemukan adalah 6, 18, 31, 39, 43, 53, dan 56, dengan tipe terseringadalah 18 dan 43. Tidak didapatkan kesamaan tipe HPV di antara pasangan HPV yangpositif. Kesimpulan. Proporsi kepositivan HPV pada suami pasien kanker serviks sebesar19% dengan tipe 18 dan 43 paling banyak didapatkan, namun tidak didapatkan kesamaan tipe HPV antara SP dengan pasien kanker serviks pasangannya.ABSTRACT Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse."