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"Summary:The quantitative structure-activity relationships (QSAR) continue to evolve quickly with an explosion of various tools and techniques. This book addresses the scope and limitations of different modeling techniques using case studies from pharmacology, toxicology, and ecotoxicology to demonstrate the utility of each technique"

"A practical guide to selecting and using CATIA toolsCATIA Core Tools: Computer Aided Three-Dimensional Interactive Applications covers this computer-aided 3D interactive application for high-end manufacturing environments. CATIA is a multi-platform application which includes CAD, CAM, and CNC applications all in one to achieve seamless transactions between applications. Dassault (creator of CATIA) releases a new edition twice a year. As most engineers do not need to know the hundreds of different applications that come with this software, this book offers the core topics in print and then allows you to download (for a fee) specialty tool(s). Specialty tools include: Solid Design / Assemblies / Surface Design / Aerospace Sheet Metal Design / Kinematics Calculations and Analysis / Composites Modeling / 3-axis NC Programming / 5-axis NC Programming / NC Turning / Knowledgeware / Stress Analysis.CATIA Core Tools: Computer Aided Three-Dimensional Interactive Applications Includes free downloadable AVI files Offers specialty tools for download (for a fee) Prepares you for the CATIA Certification exam Allows you to customize information/tools in accordance with your requirements.This unique resource provides solid fundamental knowledge of CATIA for mechanical engineers and allows them to select appropriate specialty tools to download."

"Three-dimensional (3D) transesophageal echocardiography (TEE) is a powerful visual tool which the novice or experienced echocardiographer, cardiologist, or cardiac surgeon can use to achieve a better understanding and assessment of normal and pathological cardiac function and anatomy. A complement to traditional 2D imaging, 3D TEE enables visualization of any cardiac structure from multiple perspectives. For the echocardiographer, it demands a different set of skills for image acquisition and manipulation. Real-time three-dimensional transesophageal echocardiography is a practical illustrated step-by-step guide to the latest in 3D technology and image acquisition. Each chapter systematically focuses on different cardiac structures with practical tips to image acquisition.Features :Up-to-dateSynoptic presentation of essential “how-to” and relevant clinical informationMore than 300 color figuresPractical fundamentals, including altered knobology, and how to acquire and manipulate image datasetsSystematic identification of special diagnostic issuesNormal and abnormal cardiac pathologySupplemented by the Virtual TEE Perioperative Interactive Education (PIE) website which provides free access to online resources for teaching and learning TEE : http://pie.med.utoronto.ca/TEE"

"The aim of this study is to obtain information about the mouse tongue muscle rendered using micro-computed tomography (μCT) at low, middle, and high magnifications. Three-dimensional (3D) μCT is used in various fields. Most μCT observations are restricted to hard tissue in biomaterial samples. Recently, with the use of osmium tetroxide, μCT has been effectively employed to observe soft tissue; it is now believed that μCT observation of soft tissue is feasible. On the other hand, the structure of the tongue muscle has been well studied, but cross-sectional imaging enhanced by 3D rendering is lacking. We chose the mouse tongue as a soft tissue case study for μCT and generated cross-sectional images of the tongue enhanced by 3-D image rendering with histological resolution. During this observation, we developed new methods of low-magnification observation to show the relation between the tongue muscles and surrounding tissues. We also applied high-resolution μCT in high-magnification observation of muscle fiber fascicles. Our methodological techniques give the following results: (1) For low-magnification observation (field of view: 12,000 μm), pretreatment with decalcification and freeze drying is suitable for observing the area between the muscle of the tongue and the bone around the tongue using μCT. (2) For middle-magnification observation (Field of view: 3,500 μm), the use of osmium tetroxide to observe the muscle arrangement of the tongue by μCT is suitable. (3) For high-magnification observation (Field of view: 450 μm), high-resolution μCT is suitable for observation of the transversus muscle fiber fascicles."