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"Summary: The development of the brain and nervous system is shaped not just by a genetic program, but also by the effects of multiple environmental stimuli. There are currently no book-length treatments of perinatal neurodevelopment. This book fills this gap by presenting a collection of chapters from leading experts in the field. It is comprehensive and covers all aspects of neurodevelopmental programming in lab animals and in human subjects. The third section of the book looks at ways of translating insights we have garnered from animal studies to human and clinical studies. This book is beneficial for basic researchers interested in the effects of perinatal imprinting on the development of the nervous system and associated disease"

"From neurology to methodology and back offers a translational study of neurology and technology from both sides. The fundamental topics covered range from basic concepts such as sampling and simple statistical measures via Fourier analysis to source localization. Providing clinically relevant context and introduce technical concepts, the neurological diseases presented range from epilepsy, brain tumors and cerebrovascular diseases to tremor, MS and neuromuscular diseases. All topics are presented in a true clinical neuroengineering approach.Each chapter begins with one or more patient cases for inspiration. Each case is then presented to illustrate a working example of a distinct neurodiagnostic technique, and the mathematical and physical principles underlying these techniques are explained. Finally, the author returns to the patient, and examines how the presented technology can help provide a diagnosis for each case."

"The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement."

"La diagnosi è un processo indiziario in cui l’anamnesi suggerisce le ipotesi di malattia e gli esami strumentali forniscono le prove. Nel caso della medicina legale lo specialista realizza la sintesi finale esprimendosi sull’eventuale presenza e il grado di una menomazione. La "Guida alla valutazione medico-legale del danno neurologico” facilita il procedimento che, partendo dall’osservazione del periziando, ne diagnostica la sindrome e ne quantifica l’invalidità. È perciò rivolta al medico-legale e a tutti i professionisti che in ambito pubblico o privato (Responsabilità Civile, Assicurazione Privata, Infortunistica del Lavoro, Invalidità Civile) devono pronunciarsi sull'esistenza e sull’entità di un deficit invalidante."

"This volume presents information on stem cells and cancer stem cells, therapeutic applications in disease and tissue/organ injury. Methodologies of regenerative medicine and tissue engineering are major components of this volume. Specific stem cells discussed are, human embryonic stem cells, hematopoietic stem cells, cord blood stem cells, human pluripotent stem cells, gliosarcoma stem cells, induced pluripotent stem cells, intestinal stem cells, human thyroid cancer stem cells, tumor stem cells, menstrual stem-like cells, neural stem cells, breast cancer stem cells, allogeneic mesenchymal stem cells, fetal membrane-derived mesemchynmal stem cells, and omental stem cells. The method for isolating bone marrow stromal cells is explained. Method for generating marmoset-induced pluripotent stem cells, using transcription factors, is also explained. Use of stem cell lines in therapeutic applications is discussed. Programming of stem cells is described. Methods for transplantation of stem cells are presented. Use of various types of stem cells for conditions such as stroke, ischemia, heart diseases, Alzhemier’s disease, and neurogenerative diseases in general, is explained. For example, generation of human cardiac muscle cells from adipose-derived stem cells is included. Another example is repairing bone defects using mesenchymal stem cells and mesenchymal-derived endothelial cells. Differentiation of new neurons from neural stem cells is described. Method for repairing retina condition using human embryonic stem cells is explained; these cells can induce neural differentiation. Treatment of graft-versus-host disease resulting from hematopoietic stem cell transplantation is elaborated."

"ABSTRAKAgriculture is one of major sectors of Indonesia economic source with the high volume of pesticide used. Unfortunately, adverse health effect of neurotoxic pesticide has never been reported in Indonesia. This study aimed to determine effectiveness of personal protective equipment (PPE) during applied pesticides to neurological symptoms in farmers. This study was cross-sectionally conducted from April to May 2016 in Purworejo District. About 125 farmers were selected using purposive sampling, and restriction was applied in male farmers due to the high proportion of male sprayer. Data was collected by observation and interview. Logistic regression showed protective result of PPE used during preparing (POR=0.402; 95% CI 0.114-1.423) and spraying (POR = 0.382; 95% CI 0.110-1.320), also following wind direction (POR = 0.882; 95% CI 0.271-2.872) and bathing after spraying (POR=0.328; 95% CI 0.036-3.006) after controlled by confounders. Proper PPE used during preparing and spraying pesticide, following wind direction during spraying, and bathing after spraying can decrease risk of neurological symptoms because of pesticide exposure."

"Effective behaviors optimized for various situations are enabled by various sensory information. Flow does the brain deal simultaneously with information from different sensory systems? Investigation of multisensory processing began from neuroanatomical and neurophys iological studies at the level of single neurons. Accumulation of knowledge concerning neurons and progress in recording techniques of human brain activity have led to a massive expansion in recent neuroscientific studies using various combinations of brain activity recording and cognitive tasks. In this paper, we briefly review recent neuroscientific studies related to multisensory convergence and interaction, focusing on electrophysiological and imaging studies in humans."