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"Readers will find this book an invaluable reference on the design of experiments. It contains hard-to-find information on topics such as change-over designs with residual effects and early treatment of analysis of covariance. Other topics include linear models and quadratic forms, experiments with one or more factors, Latin square designs, and fractions of 2n factorial designs. There is also extensive coverage of the analysis of incomplete block designs and of the existence and construction of balanced and partially balanced designs.A new preface (to the classics edition) describes the changes made in experimental design since the book was first published in 1971. It discusses the use of personal computers to analyze data and details the emergence of industrial statistics."

"Written for animal researchers, this book provides a comprehensive guide to the design and statistical analysis of animal experiments. It has long been recognised that the proper implementation of these techniques helps reduce the number of animals needed. By using real-life examples to make them more accessible, this book explains the statistical tools employed by practitioners. A wide range of design types are considered, including block, factorial, nested, cross-over, dose-escalation and repeated measures and techniques are introduced to analyse the experimental data generated. Each analysis technique is described in non-mathematical terms, helping readers without a statistical background to understand key techniques such as t-tests, ANOVA, repeated measures, analysis of covariance, multiple comparison tests, non-parametric and survival analysis. This is also the first text to describe technical aspects of InVivoStat, a powerful open-source software package developed by the authors to enable animal researchers to analyse their data and obtain informative results""