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"Nevus of Ota is a dermal melanocytic nevus which is characterized by benign hamartomatous hyperpigmentation.Clinically it presents as a congenital or acquired blue or gray patch on the face and is distributed on the ophthalmic,maxillary, and mandibular branches of the trigeminal nerve. It is most commonly found in Japanese populationsand is rare in the Indian subcontinent. It affects only 0.014 – 0.034% of the Asian population and is less commonin the male population, with a male to female ratio of 1.4:8. The involvement of pigmentation over the pinna of theear and the oral mucosa is extremely rare with very few cases reported in scientific literature. The case reportedhere is a case of nevus of Ota, with a rare intraoral presentation on the hard palate, crossing the midline."

"Latar belakang : nevus melanositik didapat (NM) adalah salah satu kelainan pigmentasi melanositik yang dapat menjadi prekursor potensial melanoma. Telah diketahui bahwa tipe kulit putih merupakan salah satu faktor risiko terjadinya melanoma. Pola dermoskopi NM pada populasi kulit putih memiliki gambaran dermoskopik yang berbeda pada setiap tipe kulit (tipe I ? IV) menurut klasifikasi Fitzpatrick. Belum pernah dilaporkan perbedaan gambaran dermoskopik pada tipe kulit orang Indonesia yang umumnya berkulit sawo matang dengan tipe kulit IV dan V. Dianggap penting untuk mengetahui karakteristik gambaran klinis dan dermoskopik NM pada tipe kulit orang Indonesia yang meliputi tipe kulit III, IV dan V. Metode : penelitian ini menggunakan rancangan potong lintang, pada 96 subyek penelitian (SP) dewasa (usia 18-60 tahun) di Poliklinik IKKK RSCM Jakarta terbagi merata untuk setiap tipe kulit III, IV dan V. Dilakukan pemeriksaan gambaran klinis dan dermoskopik NM pada tiap SP. Gambaran klinis yang dinilai adalah morfologi klinis dan warna lesi. Hasil : didapatkan gambaran klinis NM yang paling banyak adalah lesi datar (88,44%), berwarna cokelat gelap (51,43%), dengan median ukuran 2 mm. Pola dermoskopik yang paling banyak ditemukan pada seluruh lesi NM adalah retikular (33,40%). Terdapat proporsi dan kecenderungan yang semakin meningkat pada pola retikular dengan meningkatnya kegelapan tipe kulit orang Indonesia (tipe kulit IV terhadap tipe kulit III OR 1,4 (95% CI 0,5-4,0); tipe kulit V terhadap tipe kulit III OR 1,7 (95% CI 0,6-4,8)). Kesimpulan : Tidak terdapat perbedaan gambaran klinis NM pada tiap tipe kulit orang Indonesia. Terdapat perbedaan pola dermoskopik pada tipe retikular dengan proporsi yang makin meningkat sesuai dengan tipe kulit yang makin gelap.

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Background : Acquired melanocytic nevi (MN) is one of melanocytic pigmentation disorder, which can be a potential precursor of melanoma. Fair skin type has been known as one of the risk factor for melanoma. The dermoscopic pattern of MN in white population is different among the skin types (type I ? IV) according to Fitzpatrick?s classification. The difference in dermoscopic pattern of MN among the skin types of Indonesian people, which commonly dark brown with types IV and V, has not been reported. It is important to know the clinical characteristics and dermoscopic pattern of MN in Indonesian people skin types, which includes the skin types of III, IV and V.

Method : We performed a cross sectional study in 96 adult patients (18-60 years old), distributed equally for each skin type III, IV and V, at the Dermatovenereology outpatient clinic Dr Cipto Mangunkusumo hospital Jakarta. Each subject was examined for clinical and dermoscopic pattern. Clinical characteristic include clinical morfology and color.

Result : The study found that the most frequent clinical characteristics of MN were planar lesion (88.44 %), dark brown color (53.43%), with median size 2 mm. The most frequent dermoscopic pattern in all MN lesions was reticular (33.40 %). There was increasing proportion and odds within reticular pattern with the increase of skin?s darkness of Indonesian people (skin type IV to type III with OR 1.4 (95% CI 0.5-4.0); skin type V to type III with OR 1.7 (95% CI 0.6-4.8), respectively).

Conclusion : Clinical characteristics were not significantly different among the skin types of Indonesian people. There was difference on dermoscopic pattern within the reticular type, showing an increase of its proportion in accordance with the darker skin types."

"The “Abtropfung” theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the “Hochsteigerung” theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis."

"The lateral periodontal lateral cyst (LPC) is an uncommon developmental odontogenic cyst defined as a radiolucent lesion which develops along the lateral aspect of an erupted vital tooth. LPC represents approximately 0.8% to 2% of all odontogenic cysts. The most frequently reported location of a lateral periodontal cyst is the mandibular caninepremolar area, followed by the anterior region of the maxilla. The lateral periodontal cyst is usually asymptomatic and presents as a round, oval or teardrop-like well-circumscribed inter-radicular radiolucent area, usually with a sclerotic margin lying between the apex and cervical margin of the teeth. The lateral periodontal cyst usually is seen in the fifth to sixth decade of life with a male preponderance. This paper reports an atypical case of an inter-radicular radiolucent cystic lesion in located between the mandibular central incisor and the canine area in an 87-year-old female patient mimicking clinically and radiographically as a residual cyst but histopathologicallyconfirmed as a lateral periodontal cyst. "

"ABSTRACTHepatocellular adenoma is an extremely rare benign tumor of the liver which predominantly in young women. Its rare incidence with estimated 3-4 cases per 1.000.000 annually makes it a diagnostic challenge. Here we present a 30-year-old female patient with hepatocellular adenoma without classic risk factors. A series of work up tools have been performed in order to diagnose the condition. None but excision biopsy from segmental resection had been showed to increase diagnostic confidence. This case illustrates the role of immunohistochemical staining from excision biopsy as the best diagnostic modality of hepatocellular adenoma as well as therapeutic modality to prevent malignant transformation."

"ABSTRACTAlthough basal cell carcinoma (BCC) is a common skin tumor, very rare cases of BCC arising from upper vermilion mucosa of lip have been reported previously. This tumor basically, originates from pillar structures and the involvement of the vermilion lip contrasts this concept so it is devoid of hair follicles and sweat glands. The exact pathogenesis of vermilion lip BCC is not clear but it has been postulated that the neoplasm originates from the pluripotential epithelial cells of the oral mucosa and epidermis. On the other hand, some authors consider their origin from ectopic sebaceous glands. Herein, we report a 34- year-old man with an asymptomatic ulcerated lesion on the upper left lip vermilion mucosa .The diagnosis of BCC was confirmed with histopathological examination after incisional biopsy of the mucosal neoplasm. After surgery of lip lesion, no recurrency was seen after 3 months follow-up the patient."

"Laporan magang ini membahas mengenai pengurus Rumpin Dharma Vidya dalam mengembangkan Rumah Pintar Dharma Vidya dilihat dari sisi kelembagaan dan organisasi, pemasaran, keuangan dan produksi. Penulis memfokuskan pada sentra kriya sebagai objek penelitian.Penelitian ini menggunakanm metode statistik deskrptif yaitu dengan menganalisis data dengan cara mendeskripsikan atau menggambarkan data yang telah terkumpul baik data sekunder maupun data primer. Rumah Pintar Dharma Vidya berpotensi untuk menjadi UMKM namun hingga saat ini Rumah Pintar Dharmna Vidya masih sebagai tempat belajar bagi anggotanya, dari sentra kriya sudah banyak ibu-ibu yang sudah dapat mandiri untuk menjual produk yang mereka jual. Pada bagian terakhir dari penelitian ini penulis memberikan saran bagi Rumpin Dharmma Vidya, SIKIB dan Dharma Wanita Persatuan Kementrian PU.

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This Internship report discuss about the board in developing Rumah Pintar Dharma Vidya in terms of institutional and organization, production, marketing and financing. The writer focused on the craft center as the object of the research. This research use descriptive statistical methods to analyze the data in a way to describe or represent both primary and secondary data that have been collected. Rumah Pintar Dharma Vidya have the potential to be a SMEs but, Rumah PintarDharma Vidya still become a learning place for the members. Craft center have developed mothers to be an entrepreneur. In the last section the writer provide suggestions for Rumah Pintar Dharma Vidya, SIKIB and DWP as a Ministry of Public Works."

"Recurrent intraoral herpes infection (RIH) is one of the recurrent herpes simplex virus type-1 infections (HSV-1). It presents as single or clustered painful ulcers occur mainly on the keratinized mucosa, with the size of one to five millimeter. The Onset of RIH is considered to be associated with various endogenous and exogenous triggers. Therefore, it is important to recognize each individual triggers to prevent and to minimize and the infection for recurring. This report will describe three cases of RIH associated with emotional and physical stress. All patients have experienced continous recurrence of the disease for almost a year. Symptoms included painful multiple minute ulcers on oral mucosa initiated with fever. Serology investigation on antibody against HSV-1 confirmed a reactive elevation in these patients. Treatment consisted of acyclovir per oral 1000 mg daily per oral, counseling on stress condition and intake of nutritionalsupplementation. Nevertheless, stress conditions were difficult to overcome, therefore long-term medications were recommended to prevent recurrence episodes. One patient was taken a long-term acyclovir therapy and the other two patients were taken long-term acyclovir therapy with Phyllanthusniruri (Meniran) supplementation. Follow-ups on three cases showed the benefit of taking Phyllanthusniruri (Meniran) supplementation as reduction in RIH symptoms, shorten healing time and prolonged recurrence interval. "