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"Exfoliative cheilits is a rare chronic superficial inflammation disorder which affect vermilion border of the lips, especially lower lip. This disorder mostly happens in woman. The characteristics of this disease are a large amount production and desquamation of the keratin layers. The etiology and pathogenesis of exfoliative cheilitis is unknown. Diagnosis of exfoliative cheilitis can only be established if the conditions of the disease couldn't be connected to others factors , exfoliative cheilitis is very resistant to many treatment modalities which gave a difficulty to determine a therapy with an optimum result. Topical steroid was the most effective therapy for the disease. Antifungal therapy can be used only if there is a secondarily infection caused by Candida. This case report is about an exfoliative cheilitis on 42 years- old women with unknown etiology background. On intra-oral examination we found out that there were several focus of infections that can delay the healing proccess. The patient's conditions wereresolved after a few month of topical steroid therapy, a month of antifungal therapy and a management of the focus of infections. An exact diagnosis, an appropriate management, good corporation between sections which are related to patient condition and patient corporation are very important on the healing of exfoliative cheilitis."

"ABSTRAKBibir atas dan bibir bawah membentuk bagian bawah dari profil jaringan lunak wajah yang sangat erat hubungannya dengan gigi geligi. Untuk melakukan koreksi ortodonti pada pasien dengan profil cembung, perlu dipertimbangkan kemungkinan terjadinya perubahan jaringan lunak sebagai akibat perubahan posisi anteroposterior gigi insisif atas. Retraksi insisif atas, tidak diikuti perubahan kontur bibir secara proposional. Oleh karena itu dilakukan penelitian mengenai banyaknya pengaruh retraksi gigi insisif atas terhadap perubahan posisi bibir atas dan bibir bawah. Selain itu juga diteliti hubungan antara tebal bibir, over jet dan perubahan inklinasi insisif atas dengan perubahan posisi bibir tersebut. Penelitian ini merupakan suatu studi klinis retrospektif. Sampel terdiri dari 30 foto sefalometri pasien dengan maloklusi kelas I protrusi dental maksiler dan kelas II divisi 1, usia > 16 tahun yang diukur sebelum dan setelah selesai perawatan. Dan hasil penelitian didapat persamaan regresi, yaitu: perubahan bibir atas = 0,319 x banyaknya retraksi insisif atas (dalam milimeter) + 0,182, perubahan posisi bibir bawah = 0,526 x banyaknya retraksi insisif atas (dalam milimeter) + 0,448, perubahan posisi bibir bawah = 0,826 x perubahan posisi bibir atas (dalam milimeter) + 1,176. Tebal bibir, over jet dan perubahan inklinasi insisif atas tidak berhubungan dengan perubahan posisi bibir atas dan bibir bawah."

"Indonesian Journal of Dentistry 2006; Edisi Khusus KPPIKG XIV: 427-430Lip sucking occurred usually on lower lip and probably caused by psychological or environment factor and mostly found on school ages children. Correcting this abnormal habit as early as possible will gave positive correction to malocclusion Practicing myofunctional therapy gradually will eliminate the abnormal habit. ln this report lip sucking bad habit was treated with lip bumper and the severity of this bad habit was decreased in six months."

"ABSTRAKPenelitian ini dilakukan dengan tujuan mengetahui hubungan cheilitis angularis dan status gizi yang terjadi pada anak sekolah dasar di kecamatan Pacet kabupaten Cianjur. mengingat hingga kini belum ada laporan mengenai hal tersebut. Penelitian dilakukan pada anak sekolah dasar yang berumur 5-15 tahun. yang berasal dari 3 sekolah dasar yang dipilih secara acak sederhana dari 10 sekolah dasar yang ada di kecamatan tersebut. Selanjutnya dari 3 sekolah dasar terpilih 315 anak yang merupakan sampel yang diperoleh secara acak sistematis. Pemeriksaan klinis cheilitis angularis dilakukan dibawah penerangan sinar matahari langsung, dan penentuan status gizi dilakukan secara antropometrik. Hasilnya ditemukan 85 anak yang menderita cheilitis angularis. Persentase cheilitis angularis tertinggi didapatkan pada kelompok umur 6-7 tahun dan menurun sejalan dengan peningkatan umur. Cheilitis angularis ditemukan lebih banyak pada pria {65%) daripada wanita (35%). Dari 85 anak yang menderita cheilitis angularis. 47 anak didapatkan dengan status gizi kurang dan 38 anak dengan status gizi baik dengan X2 hitung pada α 0.05. dk1=6.29. Sedangkan hubungan keparahan dan status gizi didapatkan X2 hitung pada α 0.05. dk3=0.05. Dapat disimpulkan penelitian ini memperlihatkan adanya hubungan terjadinya cheilitis angularis dan status gizi. tetapi tidak ditemukan adanya hubungan keparahan cheilitis angularis dan status gizi."

"Tingginya konsumsi ayam meningkatkan pembuangan limbah bulu ayam, yang mengandung sekitar 90% keratin, menyebabkan pencemaran lingkungan. Keratin, protein struktural utama dalam jaringan hewan, berfungsi untuk berbagai aplikasi biomedis dan memerlukan ekstraksi ramah lingkungan. Penelitian ini mengoptimasi ekstraksi keratin dari bulu ayam menggunakan cairan ionik 1-Butyl-3-Methylimidazolium Asetat ([Bmim]-Asetat) dengan bantuan ultrasonic bath. Hasil penelitian menunjukkan bahwa metode panas dengan waktu 120 menit menghasilkan yield keratin tertinggi sebesar 78.20% dibandingkan metode optimasi ultrasonik dan metode ultrasonik tanpa optimasi. Karakterisasi FTIR menunjukkan spektra konsisten dengan struktur keratin, dan uji Bradford menunjukkan konsentrasi protein tertinggi pada metode panas dengan 112.42 mg/mL dibandingkan metode ultrasonik 120 menit dan optimasi ultrasonik 120 menit yang menghasilkan 12.13 mg/mL dan 8.834 mg/mL masing-masing. Analisis SDS-PAGE memastikan keberadaan protein keratin pada sampel hasil ekstraksi dengan berat molekul yang terlihat sebesar 10 kDa. Kombinasi gelombang ultrasonik dan suhu 90 oC dapat meningkatkan efisiensi ekstraksi dan pemulihan keratin dari limbah bulu ayam, menjadikannya metode yang lebih efisien dan ramah lingkungan.

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The high consumption of chicken increases the disposal of chicken feather waste, which contains about 90% keratin, leading to environmental pollution. Keratin, the main structural protein in animal tissues, serves various biomedical applications and requires environmentally friendly extraction methods. This study optimizes the extraction of keratin from chicken feathers using the ionic liquid 1-Butyl-3-Methylimidazolium Acetate ([Bmim]-Acetate) with the assistance of an ultrasonic bath. The results show that the heat method with a duration of 120 minutes produced the highest keratin yield of 78.20%, compared to the optimized ultrasonic method and the non-optimized ultrasonic method. FTIR characterization indicated spectra consistent with the structure of keratin, and the Bradford assay revealed the highest protein concentration in the heat method at 112.42 mg/mL, compared to 12.13 mg/mL and 8.834 mg/mL in the 120-minute ultrasonic and optimized ultrasonic methods, respectively. SDS-PAGE analysis confirmed the presence of keratin protein in the extracted samples with a visible molecular weight of 10 kDa. The combination of ultrasonic waves and a temperature of 90°C can enhance the efficiency of keratin extraction and recovery from chicken feather waste, making it a more efficient and environmentally friendly method."

"Criminal action has shown progressive increase in quality or quantity. To solve criminal cases, important data are needed in identifying individuals. The method of lip print (LP) identification can be applied in certain cases when lip prints can be found in e.g. spoon, glass, fruit etc. The prints can be analyzed in principle to reveal the characteristics of lip position. A study was conducted to compare the normal lip print with open, smile and kiss positions of the lips. Lip prints of 44 students of the University of Indonesia were taken by using transparent cellotape. The pattern types of the lip prints on 8 quadrants were determined using the method of Suzuki, and Mann-Whitney test to 95% confidence limit was used to indicate statistical significance. The results indicate that for the types of LP in all quadrants, there is no difference of between the types of LP from open, smile, kiss or normal position. In conclusion, while the pattern of lip print is specific for an individual and useful for identification, there are no significant differences between the pattern types of LP and normal lip position."

"ABSTRAKLatar Belakang: Cheilitis angularis adalah penyakit inflamasi yang dipicu oleh faktor genetik, lingkungan dan agen infektif. Gen Toll Like Receptor 2 (TLR2) merupakan komponen penting dalam respon imun innate. Tujuan: Penelitian ini bertujuan untuk menganalisis distribusi polimorfisme gen Toll Like Receptor 2 (TLR2) pada cheilitis angularis dan non cheilitis angularis. Metode: 50 sampel cheilitis angularis dan 50 sampel non cheilitis angularis digunakan dalam penelitian ini. Campuran TLR2 16934 T/A dengan ddH2O, enzim polimerase dan DNA template dianalisis menggunakan teknik PCR RFLP, yang menggunakan HphI sebagai enzim restriksi, dilanjutkan dengan elektroforesis. Hasil: Genotip terbanyak yang ditemukan pada cheilitis angularis dan non cheilitis angularis adalah genotip TT. Jumlah genotip dan alel polimorfik paling banyak ditemukan pada cheilitis angularis (22% dan 13%) dibandingkan non-cheilitis angularis (12% dan 6%). Uji Continuity Correction menunjukkan tidak terdapat perbedaan bermakna antara cheilitis angularis dan non-cheilitis angularis. Kesimpulan: Terdapat hubungan antara polimorfisme gen TLR2-16934 T/A dan cheilitis angularis.

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ABSTRACT

Background: Angular cheilitis is an inflammatory disease induced by genetic, environmental and infective agent factors. Toll Like Receptor 2 (TLR2) gene is essential components for innate immunity response. Objective: This study aimed to analyzed distribution of Toll Like Receptor 2 (TLR2) gene polymorphism in angular cheilitis and non angular cheilitis. Methods: 50 samples angular cheilitis as case group and 50 samples non angular cheilitis as control group were used in this research. TLR2-16934 T/A mixed with ddH2O, polymerase enzyme and DNA template were analyzed using PCR RFLP technique, which used HphI as restriction enzyme, then followed by electrophoresis. Subsequently assessed with statistical analysis using Continuity Corrections test. Results: The most genotype found in angular cheilitis and non angular cheilitis was TT genotype. The amount of polymorphic genotype and allele were recorded greater in angular cheilitis (22% and 13%) than non-angular cheilitis (12% and 6%). Continuity Corrections test showed no significant differences between angular cheilitis and non ngular cheilitis (p-value=0,287). Conclusion: There is an association between TLR2-16934 T/A gene polymorphism and angular cheilitis."

"Endodontic instruments such as file or reamer has potential risk to breakage during cleaning and shaping procedure especially in curved canals. In this case the instrument was fractured because it was forced into the dentin walls to gain deeper penetration, and its removal result in breakage. In this case report removal of the instrument fragment in root canal with conventional technique was failed. So it was decided to continue the treatment, with the consideration that there is no complain within one month observation."

"The management of failure case resulting form mummification treatment Signs of successful treatment folloewing mummification are the absence of clinical complaints, the formation of secondary cement, and no periapical pathosis present. Treatment about amputation the infected pulp, which has been devitalized in the pulp chamber and leaving the necrotic pulp tissues in root canal is no longer in accordance with treatment tenet now a day. The remaining necrotic tissues is a focus of infection capable of disturbing biologic healing of tissues. Three cases of root canal treatment following pulp mummification which has been done causes complaints from discomfort to severe pain and the infections spread to periapical tissue in 2, 10, and 22 years afterwards. The results of the treatment are good and periapical radiolucency shawing signs of diminution and disappearance. Evaluation on each case was done in 3 months, 6 months and 2 years after the root canal treatment."