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"Hamartoma: Prosedur diagnosis pada kasus dengan tampilan klinis yang tidak spesifik. Hamartoma merupakan lesi dengan disorganisasi pertumbuhan sel matur dan jaringan yang berlebihan, dapat terjadi di rongga mulut dengan gambaran tidak khas dan menyerupai neoplasma. Laporan kasus ini memaparkan gambaran klinis hamartoma besertapenegakan diagnosisnya pada pasien pria 37 tahun. Pasien tersebut memiliki riwayat lesi kulit berupa plak merah pada pipi kiri yang telah terlihat sejak lahir. Lesi tersebut dirasakan membesar dan mengganggu pada usia 22 tahun. Setahun kemudian dilakukan operasi pengurangan massa lesi, namun tetap meninggalkan gambaran kemerahan. Tiga belas tahun setelah operasi, timbul lesi putih di pipi kiri bagian dalam yang dalam waktu setengah tahun membesar hingga berukuran10 x 8,5 x 6 cm dan meluas sampai bibir bawah. Prosedur diagnosis dilakukan berupa pemeriksaan klinis dan penunjang yakni biopsi, CT scan, dan radiograf dengan kesimpulan awal neuroma. Selanjutnya dilakukan biopsi ulang dengan kesimpulan diagnosis hamartoma. Disimpulkan bahwa biopsi yang adekuat dan representatif, serta penyertaan informasi klinis yang memadai diperlukan untuk membedakan hamartoma dengan lesi oral lainya.

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Hamartoma is a benign tumor-like lesion composed of overgrowth of mature cells and tissues. Along with its unspecific appearance, it may occur in the oral cavity and bear resemblance to the other lesions. In this report we describes the clinical appearance of hamartoma as well as the diagnosis method in the case of a 37-year-old-man. The patient explained that he already has redness plaque lesion on his skin left cheek region since he was born. The lesion was sensed to grow anddiscomfort at the age of 22. A surgical therapy had been performed to reduce the size of lesion one year after, but the redness plaque still existed. Thirteen years following the operation, white lesion appeared on the inner left cheek 10 x 8.5 x 6cm of size and extended onto lower lips within half a year. Diagnostic procedure was carried out such as biopsy, CT-scan and radiography with neuroma as an initial conclusion. New histopathological examination confirmed the diagnosis of hamartoma. It is concluded that adequate and appropriate biopsy procedure along with sufficient clinical information are needed to develop a proper diagnosis to distinguish hamartoma from other oral lesions."

"Kebutuhan perawatan dan status kesehatan gigi dan mulut tuna netra di Phitsanuloke, Thailand. Tidak banyak informasi mengenai status kesehatan gigi dan mulut pada tuna netra di Thailand. Tujuan: Menganalisa status dan kebutuhan perawatan kesehatan gigi dan mulut pada tuna netra di Thailand. Metode: Subjek penelitian ini adalah 146 tuna netra (70 laki-laki dan 76 perempuan dengan rerata umur 48,8±5,9) yang bertempat tinggal di Phitsanuloke, Thailand. Kuesioner digunakan untuk mendapatkan informasi mengenai persepsi subjektifmasalah kesehatan gigi dan mulut, fungsi oral dan perilaku. Pemeriksaan oral dilakukan untuk menganalisa Decay Missing Filling Teeth (DMFT), Simplified Oral Hygiene Index (OHIS) dan prosthetic needs index. Hasil: Rerata DMFT subjek yang diperiksa adalah 16 (DT=4,4, MT=10,2, FT=1,4), rerata jumlah gigi yang masih ada 15,5. 35% memerlukan tambalan gigi dan 12,3% membutuhkan pencabutan gigi. 34,8% memiliki penyakit periodontal dengan rerata OHIS 2,52. 38% subjek membutuhkan gigi tiruan sebagian atas dan bawah. Tuna netra mengalami masalah fungsi oral (masalah dalam berbicara 26,5%, masalah penelanan 32,6%, masalah pengecapan 29,2% dan masalahpengunyahan 45,2%). Simpulan: Status kesehatan gigi dan mulut tuna netra rendah karena kehilangan gigi yang banyak, karies dan penyakit periodontal. Oleh karena itu sangatlah penting untuk memliki pendekatan program preventif yang tepat untuk meningkatkan kesehatan gigi dan mulut populasi tersebut.

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There is little information on the oral health status of visual impairment in Thailand. Objective: To investigate the oral health status and dental treatment needs of visual impaired Thai. Method: The subjects were 146 visual impairment (70 males and 76 females, mean age 48.8 ± 5.9), who live in Phitsanuloke, Thailand. Information on self-perceived oral health problems, oral function and oral health behavior was obtained via questionnaires. Oral examinations investigated the Decay Missing Filling Teeth (DMFT), Simplified Oral Hygiene Index (OHIS) andprosthetic needs index. Results: The mean DMFT score was 16.0 (DT=4.4, MT=10.2, FT=1.4), the mean number of teeth present was 15.5. 35% of subjects needed dental fillings and 12.3% required tooth extractions. 34.8% had periodontal disease and mean OHIS score were 2.52. Thirty-eight percent of subjects need both upper and lower partial dentures. Visual impaired suffer from oral function problems (speaking problem 26.5%, swallowing problem 32.6%, tasting problem 29.2% and chewing problem 45.2%). Conclusion: The oral health status of visual impairment was poor due to high levels of tooth loss, caries experience and periodontal disease. Therefore, it is important to have a proper preventive approach and service delivery programs to improve the oral health condition of this population."

"This volume presents the proceedings of the International Conference on Biomedical and Health Informatics (ICBHI). The conference was a new special topic conference and a common initiative by the International Federation of Medical and Biological Engineering (IFMBE) and IEEE Engineering in Medicine and Biology Society (IEEE- EMBS). BHI2015 was held in Haikou, China, 8-10 October 2015. The main theme of the BHI2015 is The Convergence: Integrating Information and Communication Technologies with Biomedicine for Global Health.The ICBHI2015 proceedings examine enabling technologies of sensors, devices and systems that optimize the acquisition, transmission, processing, storage, retrieval, use of biomedical and health information as well as to report novel clinical applications of health information systems and the deployment of m-Health, e-Health, u-Health, p-Health and Telemedicine. "

"This book goes beyond basic history and physical examination to help you master the diagnostic reasoning process. You'll develop this key skill by following assessment guidelines that focus on a specific complaint rather than beginning with a previously established diagnosis or disease entity."

"This book is a compendium of the ICCMIA 2018 proceedings, which provides an ideal reference for all medical imaging researchers and professionals to explore innovative methods and analyses on imaging technologies for better prospective patient care. This work serves as an exclusive source for new computer assisted clinical and medical developments in imaging diagnosis, intervention and analysis. It includes articles on computer assisted medical scanning techniques, computer-aided diagnosis, robotic surgery and imaging, imaging genomics, clinically-oriented imaging physics and informatics, augmented-reality medical visualization, imaging modalities, computerized radiology, oncology, and surgery. Moreover, information on non-medical imaging that has medical applications such as multi-photon microscopy and confocal, photoacoustic imaging, optical microendoscope, infra-red radiation, and other imaging modalities is also represented."

"Essential radiology, third edition , is an extensively revised and updated text that provides a highly engaging, integrated overview of the use of radiology in every specialty and subspecialty, covering all imaging modalities and organ systems. It gives medical students in radiology clerkships a solid understanding of how each imaging modality works and how a variety of pathologic conditions appear on different imaging modalities."

"Le contenu de cet ouvrage est majoritairement centré sur l'échographie pulmonaire et ses principales applications : le BLUE-protocol (abord d'un patient en défaillance respiratoire aiguë), avec les retombées sur les explorations des autres organes (coeur, veines) et l'exploration hémodynamique (FALLS-protocol), l'ensemble couvrant les deux-tiers du livre. Le poumon aigu du nouveau-né bénéficie de tout un chapitre.Une large place est faite à l'échographie interventionnelle - atout majeur de l'échographie critique - et à des applications telles qu'abord veineux sous-clavier, ponction pleurale simplifiée, infarctus mésentérique, pneumopéritoine, hypertension intracrânienne, abord de la veine cave supérieure... Les pièges techniques sont expliqués en détail.Ce livre est la traduction française de Whole Body Ultrasonography in the critically III. Il permet au réanimateur de poser un diagnostic rapide et de proposer un traitement immédiat en utilisant la voie de la simplicité (matériel, approches). C'est un guide ouvrant la voie à une nouvelle forme de médecine visuelle."

"Functional neuroradiology : principles and clinical applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD) MRI : basic principles and clinical applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of diffusion, perfusion, permeability, MR spectroscopy, positron emission tomography, BOLD fMRI and diffusion tensor imaging.With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, functional neuroradiology is divided into 9 major sections, including : physical principles of all key functional techniques, lesion characterization using diffusion, perfusion, permeability, MR spectroscopy, and positron emission tomography, an overview of BOLD fMRI physical principles and key concepts, including scanning methodologies, experimental research design, data analysis, and functional connectivity, eloquent cortex and white matter localization using BOLD fMRI and diffusion tensor imaging, clinical applications of BOLD fMRI in neurosurgery, neurology, psychiatry, neuropsychology, and neuropharmacology, multi-modality functional neuroradiology, beyond proton imaging, functional spine and CSF imaging, a full-color neuroanatomical brain atlas of eloquent cortex and key white matter tracts and BOLD fMRI paradigms.By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research."

"Clinical Research in Oral Health surveys the essentials of clinical research in oral health, anchoring these principles within the specific context of the oral health arena. Addressing research questions exclusively applicable to dentistry and oral health, the book thoroughly illustrates the principles and practice of oral health clinical research. Clinical Research in Oral Health also clarifies the framework of regulatory issues and presents emerging concepts in clinical translation, relating the research principles to clinical improvemen"

"Latar Belakang : Karsinoma sel skuamosa rongga mulut (KSSRM) memiliki insidensi yang cukup tinggi di Indonesia. KSSRM memiliki faktor risiko yang sangat beragam, di antaranya konsumsi produk tembakau, kebiasaan minum minuman beralkohol, konsumsi areca nut, faktor genetik, lokasi tumor, jenis kelamin, dan usia. Biopsi dan pemeriksaan histopatologis dengan pewarnaan hematoxylin-eosin masih menjadi gold standard dalam diagnosis definitif KSSRM. Derajat diferensiasi KSSRM umum digunakan sebagai kriteria untuk mengklasifikasi keparahan jaringan kanker. Namun, diperlukan gambaran histopatologis lain yang dapat digunakan untuk menentukan derajat diferensiasi KSSRM. Pleomorfisme nuklear mengacu pada variasi ukuran dan bentuk inti sel. Peningkatan pleomorfisme nuklear telah diasosiasikan dengan peningkatan keganasan dan metastasis kanker. Jumlah mitosis atau jumlah sel yang sedang mengalami pembelahan, telah dihubungkan dengan keganasan, prognosis yang buruk, dan metastasis pada KSSRM. Infiltrasi limfoplasmasitik didefinisikan sebagai fenomena invasi sel-sel inflamasi seperti limfosit dan plasma pada daerah peritumoral sebagai respons imun tubuh terhadap sel kanker. Penurunan infiltrasi limfoplasmasitik telah diamati memiliki hubungan dengan terjadinya metastasis nodus limfa, rekurensi, dan prognosis yang buruk. Analisis hubungan derajat pleomorfisme nuklear, jumlah mitosis, dan tingkat infiltrasi limfoplasmasitik perlu dilakukan untuk menyusun strategi perawatan yang lebih komprehensif sesuai dengan karakteristik derajat pleomorfisme nuklear, jumlah mitosis, dan tingkat infiltrasi limfoplasmasitik pasien. Tujuan : Penelitian ini bertujuan untuk menganalisis tingkat keparahan KSSRM berdasarkan derajat pleomorfisme nuklear, jumlah mitosis, dan tingkat infiltrasi limfoplasmasitiknya. Metode : Penelitian deskriptif analitik menggunakan sampel jaringan KSSRM yang diberi pewarnaan hematoxylin-eosin. Sampel tersebut diamati menggunakan mikroskop cahaya. Hasil : Derajat pleomorfisme nuklear dan jumlah mitosis memiliki hubungan yang bermakna (p<0,05) dengan derajat diferensiasi KSSRM. Hasil yang berkorelasi positif terhadap derajat diferensiasi KSSRM juga teramati pada derajat pleomorfisme nuklear (r=0,584) dan jumlah mitosis (r=0,675). Belum ditemukan hubungan bermakna (p>0,05) antara tingkat infiltrasi limfoplasmasitik dan derajat diferensiasi KSSRM. Belum ditemukan pula hubungan yang bermakna antara lokasi tumor, jenis kelamin, dan usia terhadap derajat diferensiasi KSSRM. Kesimpulan : Ditemukan hubungan antara derajat pleomorfisme nuklear dan jumlah mitosis terhadap derajat diferensiasi KSSRM. Sehingga, makin tingginya derajat pleomorfisme nuklear dan jumlah mitosis akan memperburuk derajat diferensiasi KSSRM. Namun, belum ditemukan hubungan antara tingkat infiltrasi limfoplasmasitik dengan derajat diferensiasi KSSRM. Hubungan bermakna juga belum ditemukan antara lokasi tumor, jenis kelamin, dan usia terhadap derajat diferensiasi KSSRM.

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Indonesia. OSCC has various risk factors, including tobacco use, alcohol consumption, areca nut use, genetic factor, tumor location, gender, and age. Biopsy and histopathological examination with hematoxylin-eosin staining remain the gold standard for diagnosing OSCC. Thus, the histopathological evaluation of OSCC is critical for determining prognosis and appropriate management. The degree of differentiation of OSCC is commonly used as a criterion for classifying the severity of cancer tissue. However, other histopathological features are needed to determine the degree of differentiation in OSCC. Nuclear pleomorphism refers to variations in the size and shape of cell nuclei. Increased nuclear pleomorphism has been associated with higher malignancy and cancer metastasis. The number of mitoses, reflecting the number of cells undergoing division, has been linked to malignancy, poor prognosis, and metastasis in OSCC cases. Lymphoplasmacytic infiltration is defined as invasion by inflammatory cells such as lymphocytes and plasma cells as part of the body's immune response to cancer cells. A decrease in lymphoplasmacytic infiltration has been observed to correlate with lymph node metastasis, recurrence, and poor prognosis. Analyzing the relationship between the degree of nuclear pleomorphism, the number of mitosis, and the level of lymphoplasmacytic infiltration is necessary to develop more comprehensive treatment strategies tailored to the characteristics of nuclear pleomorphism, mitotic count, and lymphoplasmacytic infiltration in OSCC patients. Objective: This study aims to analyze the severity of OSCC based on the degree of nuclear pleomorphism, number of mitosis, and the level of lymphoplasmacytic infiltration. Methods: A descriptive-analytical study was conducted using OSCC tissue samples stained with hematoxylin-eosin. These samples were observed under a light microscope. Results: The degree of nuclear pleomorphism and mitotic count showed a significant relationship (p<0.05) with the OSCC degree of differentiation. Positive correlations for nuclear pleomorphism (r=0.584) and mitotic count (r=0.675) with OSCC degree of differentiation. No significant relationship was found (p>0,05) between the level of lymphoplasmacytic infiltration and the OSCC degree of differentiation. Additionally, no significant associations were found between tumor location, gender, and age with the OSCC degree of differentiation. Conclusion: An association was found between the degree of nuclear pleomorphism and number of mitosis with the OSCC degree of differentiation. Thus, higher degree of nuclear pleomorphism and number of mitosis worsen the OSCC degree of differentiation. However, no significant relationship was observed between the level of lymphoplasmacytic infiltration and the OSCC degree of differentiation. Similarly, no significant associations were found between tumor location, gender, and age with the OSCC degree of differentiation."