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"Stress akademik mempengaruhi kesehatan jaringan periodontal dan kadar interleukin-1 beta. Stres merupakan faktor risiko penyakit periodontal yang dapat meningkatkan kadar interleukin-1 dan berperan pada kerusakan jaringan periodontal. Tujuan: menganalisis hubungan antara stres akademik pada mahasiswa program studi spesialis dengan kondisi jaringan periodontal dan kadar interleukin-1 beta dari cairan krevikular gingiva. Metode: Tiga puluh delapan subjek penelitian mengisi kuesioner Graduate Dental Environtmental Stress (GDES),pemeriksaan klinis periodontal, dan pengambilan sampel dari cairan sulkus gingiva dari delapan titik di regio anterior dan posterior serta pemeriksaan kadar interleukin-1 beta dengan Enzyme-linked Immunosorbent Assay (ELISA). Hasil: Terdapat perbedaan bermakna (p<0,05) antara tingkatan stres akademik dengan kondisi jaringan periodontal yaitu tingkat kebersihan mulut (p=0,038), indeks perdarahan gingiva (p=0,02), namun tidak pada kedalaman poketdan tingkat perlekatan klinis (p=0,972). Terdapat perbedaan bermakna (p=0,03) antara kadar interleukin-1 beta dengan tingkatan stres akademik. Tidak terdapat perbedaan bermakna (p>0,05) antara kadar interleukin-1 beta dengan kondisi jaringan periodontal yaitu tingkat kebersihan mulut (p=0,465), indeks perdarahan gingiva (p=0,826), kedalaman poket (p=0,968), tingkat perlekatan klinis (p=0,968). Simpulan: Stres akademik memiliki pengaruh terhadap risiko penyakit periodontal dengan peningkatan kadar interleukin-1 beta dalam cairan krevikular gingiva.

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Stress is a risk factor for periodontal disease, causing increase levels of interleukin-1 beta that involve in periodontal destruction. Objective: To analyze the relationship between academic stress in residency program students conditions and levels of interleukin-1 beta in gingival crevicular fluid. Methods: Thirty eight subjects filled the questionnaire of Graduate Dental Environtmental Stress (GDES), periodontal examination and samples of gingival crevicular fluid were tested for interleukin-1 beta with the Enzyme-linked Immunosorbent Assay (ELISA) test. Results: There were significant differences between academic stress to periodontal tissue in oral hygiene (p=0.038),bleeding on probing index (p=0.02), but no significant differences in pocket depth and loss of attachment (p=0.972). There were significant differences between academic stress to levels of interleukin-1 beta (p=0.03), but no significant differences between levels of interleukin-1 beta to periodontal tissue in oral hygiene (p=0.465), bleeding on probing index (p=0.826), pocket depth (p=0.968), and loss of attachment (p=0.968). Conclusion: Academic stress influences the periodontal risk factor and level of interleukin-1 beta."

"Mahasiswa cenderung memiliki banyak kesibukan, baik kesibukan akademik maupun kesibukan non akademik, sehingga hal tersebut dapat menjadi faktor penyebab terjadinya stres yang dikenal dengan stres akademik. Penelitian ini dilakukan kepada mahasiswa penerima beasiswa Beastudi Etos di wilayah Jakarta (mahasiswa Universitas Indonesia) dan Bogor (mahasiswa Institut Pertanian Bogor) sebanyak 89 orang dengan menggunakan teknik total sampling, dengan tujuan untuk mengetahui tingkat stres akademik yang terjadi pada mereka dengan menggunakan instrumen penelitian Academic Stress Scale (ASS). Penelitian ini dilakukan dengan analisis penelitian deskriptif dan menggunakan desain penelitian cross sectional. Hasil penelitian diperoleh mahasiswa rata-rata berusia 19,12 tahun, didominasi oleh perempuan (60,7%) dan mahasiswa tahun ke-1 (64,0%), paling banyak mengikuti 2-3 organisasi (52,8%), sebagian besar memiliki indeks prestasi kategori baik (58,4%), serta teridentifikasi memiliki tingkat stres akademik kategori stres ringan (38,2%), stres sedang (32,6%), dan stres berat (11,2%). Rekomendasi dari penelitian ini adalah perlu dilakukan penelitian mengenai hubungan stres akademik dengan berbagai faktor lain seperti pola tidur dan pola aktifitas.

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Students tend to have a lot of bustle, bustle both academic and non-academic, so that it can be factors that cause stress are known with academic stress. This research was conducted to scholarship recipients Beastudi Etos in Jakarta (Universitas Indonesia students) and Bogor (Bogor Agricultural University students) as much as 89 people by using total sampling technique, in order to determine the level of academic stress happens to them using research instruments Academic Stress Scale (ASS). This research was conducted with descriptive and analytical research using cross sectional design.

The results obtained by the students with an average age 19.12 years, dominated by women (60.7%) and students of year 1 (64.0%), the most widely followed 2-3 organizations (52.8%), partially great to have a good category of performance index (58.4%), and identified as having mild levels of academic stress (38.2%), moderate levels (32.6%), and high levels (11,2%). Recommendations from this research is necessary to do research on the relationship academic stress with a variety of other factors such as sleep pattern and activity pattern."

"The correlation between endodontic-periodontal lesion has been documented well by researches. Endodontic lesion originates from pulp, while periodontal lesion originates from periodontal tissues. Anatomically they are connected by apical foramen, lateral canal and accesories, as well as dentin tubules. The correlation appeared as the endodontic defect can be from periodontal lesion, or a periodontal defect is from a pulp tissue. Together they can emerge and form a combination lesion. Endodontic infections have been highly correlated with deeper periodontal pockets and furcation involvement in mandibular, the causal relationship between the two pathoses has not yet been established. This consensus supports the influence of degenerated or inflamed pulp that can happen on the periodintium; but not all researchers agree about the effect of periodontal disease on the pulp. Conclusion: The mechanism of endo-perio lesion need to taken care in order to have appropriate diagnostic so that the right therapy would be able to keep the teeth in the oral cavity."

"Latar belakang: Indonesia memiliki jumlah lansia yang banyak dan akan terus bertambah setiap tahunnya. Karies gigi dan karies akar merupakan masalah kesehatan gigi dan mulut yang sering dialami oleh lansia. Perilaku kesehatan gigi dan mulut merupakan salah satu faktor penyebab karies yang dapat dimodifikasi. Tujuan penelitian ini adalah untuk mengetahui hubungan perilaku kesehatan gigi dan mulut pada status karies gigi dan akar lansia di tahun 2018. Metode: Desain studi cross-sectional menggunakan data Riskesdas 2018. Jumlah sampel sebanyak 4678 subjek usia 60 tahun ke atas. Hasil: Prevalensi karies gigi dan karies akar lansia Indonesia secara berturutturut adalah 95,7% dan 95,5%. Lansia Indonesia memiliki skor rerata decay, missing, filled teeth (DMFT) sebesar 15,6 (SE 0,1) dan skor median root caries index (RCI) sebesar 38,9% (IQR 10%,77,8%). Sembilan dari sepuluh lansia Indonesia tidak mengunjungi tenaga medis gigi dalam setahun terakhir. Uji korelasi Spearman menunjukkan bahwa perilaku menyikat gigi, konsumsi makanan manis, konsumsi minuman manis, dan berkunjung ke tenaga medis gigi memiliki korelasi (p < 0,05) pada skor rerata DMFT lansia Indonesia. Hal yang mirip juga terlihat pada skor median RCI lansia Indonesia, kecuali pada korelasinya dengan makanan manis. Selain itu, perbedaan skor rerata DMFT terlihat antara kategori sosiodemografi usia, tingkat pendidikan, status ekonomi, pekerjaan dan daerah domisili. Perbedaan status karies akar juga terlihat antara kategori sosiodemografi usia, tingkat pendidikan, status ekonomi, daerah domisili, dan jaminan kesehatan. Kesimpulan: Terdapat hubungan antara perilaku kesehatan gigi dan mulut dengan status karies lansia di Indonesia. Program preventif karies, peningkatan kunjungan dokter gigi, dan adanya kebijakan pemerintah untuk menurunkan konsumsi gula pada lansia disarankan.

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Background: Indonesia has a large number of elderly and will continue to grow every year. Dental caries and root caries are dental and oral health problems that are often experienced by the elderly. Dental and oral health behavior is one of the modifiable causes of caries. The purpose of this study was to determine the relationship between dental and oral health behavior on the dental caries status and roots of the elderly in 2018. Methods: Cross-sectional study design using Riskesdas 2018 data. The number of samples was 4678 subjects aged 60 years and over. Results: The prevalence of dental caries and root caries in the Indonesian elderly were 95.7% and 95.5%, respectively. Indonesian elderly have a mean decay, missing, filled teeth (DMFT) score of 15.6 (SE 0.1) and a median root caries index (RCI) score of 38.9% (IQR 10%, 77.8%). Nine out of ten Indonesian seniors did not visit dental personnel in the past year. Spearman correlation test showed that the behavior of brushing teeth, consumption of sweet foods, consumption of sugary drinks, and visits to dental medical personnel had a correlation (p < 0.05) on the average DMFT score of the Indonesian elderly. The same thing is also seen in the median RCI score of the Indonesian elderly, except for the correlation with sweet foods. In addition, differences in DMFT mean scores were seen between sociodemographic categories of age, education level, economic status, occupation and area of ​​domicile. Differences in root caries status were also seen between sociodemographic categories of age, education level, economic status, area of ​​domicile, and health insurance. Conclusion: There is a relationship between dental and oral health behavior and the caries status of the elderly in Indonesia. A caries prevention program, an increase in dentist visits, and a government policy to reduce sugar consumption in the elderly are recommended."

"Dental caries is one of the common diseases which are attributed by many factors. Many from the adult population areafflicted with dental caries. This study aimed to determine the predictors of developing dental caries among adults.Three hundred and thirty four adults participated in this study. Information gathered were their socio-demographicbackgrounds, oral health behaviour, physical activity level, body mass index, body fat percentages, visceral fat level,and dental missing filled extracted teeth (DMFX) index. All standard protocols were observed and DMFX wasexamined using the World Health Organization (WHO) criteria. Prevalence of dental caries was 87.4%, inclusive of61.3% of female respondents with caries experience. Most of the study participants were overweight. Only consumptionof high sugar food (p=0.03) were found between dental caries and oral health behaviours. Regression analysis(p<0.001) showed that older age (p<0.001), regular visits to dental clinic per year (p=0.012), lower education level(p=0.025), and lower physical activity (p=0.008) were significant factors in developing dental caries among in thisstudy population. Older aged adults, frequent appointment with the dentist, lower education in oral health and lowerphysical activity were possible factors for dental caries presence.Sosiodemografi, Perilaku Kesehatan Gigi dan Mulut, dan Aktivitas Fisik: Berbagai Faktor Penyebab Karies.Karies gigi adalah salah satu penyakit umum disebabkan oleh banyak faktor. Banyak orang dewasa menderita kariesgigi. Penelitian ini bertujuan untuk menentukan prediktor karies gigi pada orang dewasa. Tiga ratus tiga puluh empatorang dewasa ikut berpartisipasi dalam penelitian ini. Informasi yang dikumpulkan adalah latar belakang sosiodemografis,perilaku kesehatan gigi dan mulut, tingkat aktivitas fisik, indeks massa tubuh, persentase lemak tubuh,tingkat lemak visceral, dan indeks gigi yang hilang, ditambal, dan diekstraksi (DMFX). Semua protokol standar diamatidan DMFX diperiksa mengikuti kriteria Organisasi Kesehatan Dunia (WHO). Prevalensi karies gigi adalah 87,4%,termasuk 61,3% responden perempuan dengan pengalaman karies. Sebagian besar peserta penelitian kelebihan beratbadan. Hanya konsumsi makanan tinggi gula (p=0,03) yang dapat dikaitkan dengan karies gigi dan perilaku kesehatanmulut dan gigi. Analisis regresi (p<0,001) menunjukkan bahwa usia yang lebih tua (p<0,001), kunjungan rutin ke klinikgigi per tahun (p=0,012), tingkat pendidikan yang lebih rendah (p=0,025), dan aktivitas fisik yang lebih rendah(p=0,008) merupakan faktor signifikan yang menyebabkan karies gigi pada populasi penelitian ini. Orang dewasaberusia lanjut, rendahnya frekuensi kunjungan ke dokter gigi, kurangnya pendidikan mengenai kesehatan mulut dangigi, dan aktivitas fisik yang lebih rendah merupakan faktor yang memungkinkan kehadiran karies gigi."

"Latar balakang: Early Childhood Caries seringkali dijumpai pada anak-anak dalam rentang usia kurang dari 71 bulan. Diduga kuat bakteri Streptococcus Mutans serotipe e menjadi bakteri penyebab terjadinya ECC. Imunoglobulin A (IgA) berperan didalam mulut sebagai penghambat kolonisasi dari bakteri penyebab karies gigi. Tujuan: Menganalisis keterkaitan titer IgA anti S .mutans serotipe e terhadap viskositas saliva dan skor dmft pasien Early Childhood Caries. Metode: 15 subjek ECC dari saliva pasien yang terdiri dari 8 saliva terstimulasi dan 7 saliva tidak terstimulasi yang dihitung titer IgA anti S. mutans serotipe e menggunakan teknik ELISA. Keterkaitan antara level IgA dengan viskositas saliva dan skor dmft pasien ECC dianalisis menggunakan uji korelasi. Hasil: Level IgA pada saliva yang terstimulasi lebih rendah daripada level saliva tidak terstimulasi. Adanya hubungan bermakna antara level IgA dengan viskositas saliva (r = 0.766). Tidak ditemukan adanya hubungan yang bermakna (r >0.005) antara level IgA dengan skor dmft (r= -0.413). Kesimpulan: Hasil penelitian ini menunjukan bahwa terdapat korelasi yang positif dan bermakna antara level IgA anti S. mutans serotipe e dengan viskositas saliva. Terdapat hubungan negatif dan tidak bermakna antara level IgA anti S. mutans serotipe e dengan skor dmft pasien ECC. Selain itu, titer IgA anti S. mutans serotipe e pada saliva tidak terstimulasi ditemukan lebih tinggi daripada saliva yang terstimulasi tetapi tidak bermakna.

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Background: Early Childhood caries is often found in children in the age range of less than 71 months. Allegedly bacteria Streptococcus mutans serotype e took a stake in the process of formation or the occurrence of ECC. One of the body's natural defense line is immunoglobulin A (IgA). Objective: To analyze the relationship level of IgA anti-bacterial S .mutans serotype e on the viscosity of saliva and saliva dmft score of patients Early Childhood caries. Methods: 15 patients saliva samples ECC consists of 8 saliva stimulated and unstimulated saliva 7 calculated level of IgA anti bacteria S. mutans serotype e. Observations were made using ELISA technique. IgA levels were then analyzed its association with the viscosity of saliva and saliva of patients ECC dmft score. Results: Stimulated saliva ECC patients had IgA levels were lower than unstimulated saliva levels and found no significant correlation (r> 0.005) between salivary IgA level ECC patients with a viscosity of saliva and dmft score. Conclusion: There were no significant correlation and positive correlation between levels of IgA anti S. mutans serotype e dmft score saliva of patients with ECC. Obtained a positive correlation and significant correlation between the viscosity of saliva to the value level of IgA anti S. mutans serotype e. Unstimulated saliva had IgA level anti S. mutans serotype e higher than the stimulated saliva but there was no significantly difference."

"Latar Belakang: Prevalensi karies gigi anak di Indonesia yang tinggi disebabkan karena perilaku ibu yang buruk dalam menjaga kebersihan gigi anaknya. Tujuan: Mengetahui peran lembar balik dan lembar evaluasi KMGS dalam merubah perilaku ibu terhadap kesehatan gigi mulut balita. Metode: melakukan pelatihan kader menggunakan lembar balik, pemeriksaan kesehatan gigi mulut balita, kemudian dievaluasi setelah diintervensi menggunakan lembar evaluasi KMGS. Hasil: terdapat peningkatan (57,15%) bermakna (p<0,05) perilaku ibu pada kelompok intervensi, penurunan bermakna (p<0,05) indeks plak (60%) dan skor kematangan plak (25,71%) anak. Kesimpulan: media lembar balik efektif meningkatkan perilaku ibu.

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Background: The high prevalence of early childhood caries in Indonesia is caused bymother’s behaviour of maintaining children’s oral hygiene.

Purpose: to know aboutthe role of flipchart and KMGS in maintaining mother's behaviour toward children's dental health.

Methods: training for cadre by using flipchart, examination of children's dental and oral health and evaluating after the intervention by using KMGS.

Results: there’s a significant improvement (57.15%) of mother’s behaviour (p<0,050) in intervention group, a significant reduction (p<0.05) of child plaque index (60%) and plaque maturity score (25.71%).

Conclusion: flipchart is an effective media to improve mother’s behaviour."

"Karies merupakan penyakit gigi yang banyak dijumpai pada anak-anak usia sekolah dasar di Indonesia. Walaupun tidak menimbulkan kematian, sebagai akibat dari kerusakan gigi dan jaringan pendukung gigi, dapat mennurunkan tingkat produktivitas seseorang, karena dari aspek biologis akan dirasakan sakit, sehingga aktivitas belajar, makan dan tidur terganggu. Penelitian ini dilakukan di Sekolah Dasar Negeri kelas 1 yang ada di Wilayah Kerja puskesmas Walantaka. Penelitian ini bertujuan untuk mengetahui fakor prilaku yang mempengaruhi status karies gigi pada siswa sekolah dasar dengan desain cross sectional dan alat yang digunakan untuk mengumpulkan data berupa kuesioner. Hasil Penelitian menunjukkan bahwa 238 (69,4%) dari 343 anak yang menderita karies gigi, jenis kelamin terbanyak adalah perempuan 114 (74%). Dari penelitian ini faktor yang paling beresiko terhadap status karies gigi siswa adalah Cara anak menyikat gigi (PR = 2,557), Frekuensi sering mengkonsumsi jajanan manis (PR = 2,197), Pekerjaan ibu (PR = 2,051) dan Frekuensi sikat gigi (PR = 1,782). Usaha untuk menurunkan angka karies gigi pada anak yaitu dengan meningkatkan kegiatan program Usaha Kesehatan Gigi Sekolah, melalui promotif dan preventif tentang kesehatan gigi dan mulut, melalui pemeriksaan gigi dan mulut secara rutin ke sekolah-sekolah sehingga dapat diambil tindakan untuk mencegah dan menanggulangi masalah kesehatan gigi dan mulut pada anak sekolah.

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Dental caries is a disease that is common in children of primary school age in Indonesia. Although no cause of death, as a result of tooth decay and tooth supporting tissues, may lower a person's level of productivity, because of the biological aspects will be felt sick, so the learning activities, eat and sleep undisturbed.

The research was conducted at the State Primary School Grade 1st in the Work Area Walantaka clinic. This study aims to determine the behavior factor affect the status of dental caries in primary school students with the cross- sectional design and the tools used to collect data in the form of a questionnaire.

Research results showed that 238 (69.4%) of 343 children who suffer from dental caries, is the most sex women 114 (74%). From this study the risk factors for dental caries status of students is the way children brushing their teeth (PR = 2.557), frequency often consume sugary snacks (PR = 2.197), maternal work (PR = 2.051) and frequency toothbrush (PR = 1.782).

Efforts to reduce the number of dental caries in children by increasing activity UKGS program, through promotion and prevention of oral health through oral examination regularly to schools so that they can take action to prevent and addressthe problem of oral health on school children. "

"Latar Belakang: Penyakit kardiovaskular merupakan penyebab kematian tertinggi di Indonesia. Karies gigi dan penyakit periodontal merupakan penyakit kronis terbesar di dunia termasuk di Indonesia. Tujuan penelitan untuk menguji hubungan antara karies gigi, penyakit periodontal dengan penyakit kardiovaskular pada usia produktif di Indonesia. Metode: Studi potong lintang menggunakan data survei kesehatan nasional (RISKESDAS) untuk menganalisis hubungan antara karies gigi, penyakit periodontal dengan penyakit kardiovaskular yang mempertimbangkan faktor-faktor risiko penyakit kardiovaskular yang lain. Analisis dibatasi pada populasi yang memiliki data pemeriksaan klinis gigi dan berusia 20-64 tahun. Ada 24.325 subjek masuk dalam analisis. Analisis chi-square digunakan untuk menilai hubungan bivariat, dan analisis regresi logistik ganda untuk menilai hubungan karies gigi, penyakit periodontal dengan penyakit kardiovaskular yang dikontrol kovariat untuk memperoleh hubungan murni. Hasil: Ada hubungan bermakna secara statistik (p < 0,05) antara karies gigi dengan penyakit kardiovaskular setelah dikontrol variabel umur (AOR 2,255;95%CI:1,333-3,814). Ada hubungan bermakna secara statistik (p < 0,05) antara kehilangan perlekatan periodontal dengan penyakit kardiovaskular setelah dikontrol dengan umur, gangguan emosional, diabetes dan hipertensi (AOR1,454;95%CI:1,129-1,873). Kesimpulan: Penelitian ini menambahkan bukti faktor risiko utama yang dapat dimodifikasi pada penyakit kardiovaskular.

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Background: Cardiovascular diseases is the highest cause of death in Indonesia. Dental caries and periodontal diseases are the biggest chronic diseases in the world, including in Indonesia. The research aimed to examine the relationship between dental caries, periodontal disease, and cardiovascular disease in productive age in Indonesia. Methods: A cross-sectional study using national health survey data (RISKESDAS) to analyze the association between dental caries, periodontal disease, and cardiovascular disease considering other risk factors for cardiovascular disease. Analysis was restricted to the population who had dental clinical examination data and were aged 20-64 years. There were 24,325 subjects included in the analysis. Chi-square analysis was used to assess the bivariate relationship, and multiple logistic regression to assess the relationship between dental caries, periodontal disease, and cardiovascular disease which were covariate controlled to obtain a pure relationship. Results: There was a statistically significant relationship (p <0.05) between dental caries and cardiovascular disease after controlling for age (AOR 2.255;95% CI:1.333-3.814). There was a statistically significant relationship (p <0.05) between periodontal attachment loss and cardiovascular disease after controlling for age, emotional disturbances, diabetes, and hypertension (AOR1.454;95%CI:1.129-1.873). Conclusion: This study adds to the evidence of major modifiable risk factors in cardiovascular disease"

"Latar Belakang: Berdasarkan Riskesdas 2013 lebih dari seperempat penduduk Indonesia (25,9%) mempunyai masalah kesehatan gigi dan mulut dengan karies gigi sebagai masalah yang memiliki prevalensi tertinggi di angka 53,2%. Salah satu penyebabnya adalah plak gigi, yang dapat dihilangkan dengan perilaku menyikat gigi. Waktu menyikat gigi yang selama ini dianjurkan adalah setelah sarapan dan sebelum tidur. Namun, ditemukan kerugian dan ketidak efektifan dari waktu menyikat gigi tersebut, sehingga dibutuhkan waktu menyikat gigi lain yang dapat menghilangkan plak secara efektif. Tujuan: Mengetahui perbedaan perlakuan menyikat gigi sebelum dan setelah makan terhadap derajat keasaman (pH) plak gigi sebagai faktor risiko karies. Metode: Penelitian ini menggunakan pendekatan Before-After Randomized Crossover Trial. Subjek penelitian adalah 20 mahasiswa/i FKG UI dengan rentang umur 19-22 tahun yang dipilih melalui metode purposive sampling. Penelitian dilakukan dengan membandingkan pH plak pada perlakuan menyikat gigi sebelum dan setelah makan. Perlakuan dilakukan sekali seminggu selama 2 minggu, dengan empat kali pengambilan data setiap perlakuannya, yaitu T0 (sebelum dilakukan perlakuan apapun/baseline), T1 (setelah makan/ setelah sikat gigi sebelum makan), T2 (setelah makan/ setelah sikat gigi setelah makan), dan T3 (setelah 6 jam). Subjek diambil sampel derajat keasaman (pH) plaknya menggunakan digital pH meter Horiba LAQUAtwin. Sample plak diambil di gigi 11-21 dengan menggunakan sample sheet sekali pakai. Hasil: Kedua kelompok sama-sama mengalami penurunan rata-rata pH plak setelah makan dan setelah enam jam paska perlakuan terakhir, serta mengalami kenaikan rata-rata pH plak setelah sikat gigi. Pada kelompok perilaku menyikat gigi sebelum makan rata-rata pH plak pada awal pemeriksaan adalah 7,32 dan turun menjadi 7,27 setelah 6 jam. Sedangkan pada kelompok perilaku menyikat gigi setelah makan rata-rata pH plak pada awal pemeriksaan yaitu 7,49 turun menjadi 7,41 setelah 6 jam. Kesimpulan: Tidak terdapat perbedaan yang bermakna antara perlakuan menyikat gigi sebelum dan setelah makan terhadap pH plak.

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Background: According to the 2013 Basic Health Research, more than a quarter of Indonesia's population (25.9%) have dental and oral health problems, of which the highest prevalence is held by dental caries at the rate of 53,2%. One of the causes of caries is dental plaque which can be removed by tooth brushing. Most recommended time for tooth brushing is twice a day, after breakfast and before going to bed. However, the ineffectiveness of those brushing time is found. Therefore, the effective time to tooth brushing is needed. Objective: To determine the effect of before-eating tooth and after-eating tooth brushing on the hydrogen-ion concentration (pH) of dental plaque as caries risk factor. Methods: This study used the Before-After Randomized Crossover Trial approach. The research subjects were 20 FKG UI students with an age range of 19-22 years selected through a purposive sampling method. The study was conducted by comparing the pH of plaque to the treatment of tooth brushing before and after eating. The treatment is done once a week for 2 weeks, with four times data collections, there are T0 (before any treatment / baseline), T1 (after eating / after brushing before eating), T2 (after eating / after brushing after eating) , and T3 (after 6 hours). The subjects would be sampled the acidity degree (pH) of dental plaque using a digital pH meter called Horiba LAQUAtwin. Plaque samples were taken in teeth 11-21 using a disposable sheet sample. Results: Both groups experienced a decrease in the average pH of plaque after meals and after six hours, and experienced an increase in the average pH of plaque after brushing. In the group tooth brushing before eating the average pH of dental plaque at the beginning of the examination, which was 7.32, dropped to 7.27 after 6 hours. While in the group of brushing behavior after eating the average pH of plaque at the beginning of the examination, which was 7.49, dropped to 7.41 after 6 hours. Conclusion: There was no significant difference between the treatment of tooth brushing before and after eating to the pH of plaque."