Hasil Pencarian  ::  Simpan CSV :: Kembali

"The key knowledge assembled in this book comprises today?s most comprehensive resource on Sjögren?s syndrome. Sjögren?s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others.This practical clinical resource begins with an overview of Sjögren?s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book?s contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets.Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren?s patients and physicians."

"Sjögren’s syndrome : diagnosis and therapeutics provides a thorough, multisystemic overview of the clinical manifestations of Sjögren’s Syndrome. It contains chapters pertinent across the range of medical specialties that may encounter Sjögren’s Syndrome cases. Chapters are specialty-specific, for easy reference by the relevant medical specialist. In addition to being a diagnostic guide, Sjögren’s Syndrome: Diagnosis and Therapeutics includes a section on prognosis and outcomes of Sjögren’s Syndrome patients and provides an exhaustive therapeutic update, focused on new agents and experimental techniques.The inclusion of diagnostic/therapeutic algorithms illustrates the text with clinical photographs of the main organs involved and helps the reader to make guided diagnostic and therapeutic decisions through decision-based algorithms."

"Tesis ini bertujuan untuk menilai stabilitas LAM mata kering terkait sindrom Sj gren SS yang diberikan terapi kombinasi tetes mata sodium hialuronat 0,1 SH dan hydroxypropyl HP -guar, atau monoterapi tetes mata sodium hialuronat SH. Sebanyak 17 pasien SS dalam penelitian ini dibagi ke dalam 2 kelompok. Kelompok pertama mendapatkan kombinasi SH dan HP-guar sementara kelompok kedua mendapatkan terapi SH. NIKBUT, Schirmer, skor pewarnaan okular dan sitologi impresi, serta keluhan subjektif yang dilakukan sebelum dan sesudah pemberian obat. Setelah terapi selama 28 hari, terdapat peningkatan median NIKBUT, Schirmer, skor pewarnaan okular, densitas sel Goblet dan keluhan subjektif pada mata kering terkait SS.

---

The objectives of the study is to assess the stability of dry eye LAM associated with Sj gren syndrome SS given combination therapy of sodium hyaluronate 0.1 SH and hydroxypropyl HP guar, or monotherapy sodium hyaluronic SH. A total of 17 SS patients in this study were divided into 2 groups. The first group received a combination of SH and HP guar while the second group received SH therapy. NIKBUT, Schirmer, ocular staining score and impression cytology, as well as subjective complaints made before and after drug administration. After 28 days of therapy, there was a median increase in NIKBUT, Schirmer, ocular staining scores, Goblet cell density and subjective complaints on SS related dry eyes. "

"Latar Belakang. Perkembangan teknologi dan meningkatnya peran penggunaan tangan di bidang industri, rumah tangga dan perkantoran akan meningkatkan angka kejadian STK. Hal ini akan memiliki dampak negatif di bidang medis, sosial dan ekonomi. Pemeriksaan Ultrasonografi (USG) berguna sebagai penunjang dalam mendiagnosis STK. Kemajuan dalam kualitas dan portabilitas USG telah menempatkan USG sebagai alat pilihan dalam penelitian dan penerapan klinis di bidang neurologi. USG mudah dijumpai di pelayanan kesehatan, memiliki biaya yang murah, waktu pemeriksaan yang singkat dan tidak invasif, serta memiliki sensitivitas dan spesifisitas yang cukup baik dalam mendiagnosis STK. Metode. Desain penelitian berupa studi potong lintang. Subyek penelitian adalah pasien Poliklinik Neurologi RSCM yang memenuhi kriteria inklusi dan eksklusi. Subyek diperoleh secara konsekutif. Pada subyek dilakukan wawancara, pengisian kuesioner, pemeriksan fisik, elektroneurografi dan ultrasonografi di Poliklinik Neurologi RSCM. Dilakukan analisis data menggunakan perangkat SPSS 17.0. Hasil. Diperoleh 58 subyek tangan yang masuk kriteria inklusi. Sensitivitas dan spesifisitas kombinasi gambaran klinis dan USG adalah 86,04% dan 73,33%. Sedangkan akurasi kombinasi gambaran klinis dan USG sebesar 82,75%. Terdapat kesesuaian antara pemeriksaan kombinasi klinis dan USG dengan kombinasi klinis dan elektroneurografi dalam mendeteksi STK (kappa = 0,70). Kesimpulan. Nilai sensitivitas kombinasi gambaran klinis dan USG sama dengan elektroneurografi. Sedangkan spesifisitas kombinasi gambaran klinis dan USG lebih rendah daripada elektroneurografi. Kombinasi gambaran klinis dan USG dapat digunakan sebagai alternatif pemeriksan dalam mendiagnosis STK.

---

Background. Technological development and the increased use of hands in the fields of industrial, household and office space will increase the prevalence of Carpal Tunnel Syndrome (CTS). This will have a negative impact on medical science, social and economic. Ultrasonography (USG) is useful to support diagnosis of CTS. Progress in the quality and portability of ultrasound has placed ultrasound as a chosen instrument in research and clinical application in the field of neurology. USG is easily found at the health centers, has a lower cost, a short examination time and not invasive, as well as having superior specificity and sensitivity is good enough in diagnosing CTS.

Method. A cross-sectional sectional study was conducted. The research subject were patients of the Neurology Clinic of RSCM Hospital who meet all of the inclusion and exclusion criteria.

Result. Fifthy eight hands were included in this study. The sensitivity and specificity of the combination of clinical features and ultrasonography were 86.04% and 73.33%. While, the accuracy of the combination of clinical features and ultrasonography was 82.75%. There is a conformity between the combination of clinical features and ultrasound with a combination of clinical picture and electroneurography in diagnosing CTS (kappa = 0.70).

Conclusion. The combination of clinical features and ultrasonography has similar sensitivity with electroneurography. Meanwhile, the specificity of the combination of clinical features and ultrasonography is inferior to electroneurography. Thus, the combination of clinical features and ultrasonography can be used as an alternative to electroneurography in diagnosing CTS."

"

Latar Belakang :  Carpal Tunnel Syndrome (CTS) merupakan kelainan neuropati perifer terbanyak pada ekstremitas atas akibat terjebaknya atau terjepitnya saraf medianus pada terowongan karpal. Pada pekerja seringkali diakibatkan oleh gerakan repetitif dengan fleksi dan ekstensi pada daerah pergelangan tangan, gerakan menggenggam erat, getaran. Kasus CTS merupakan gangguan muskuloskeletal pada ekstremitas atas yang mengakibatkan pembiayaan kesehatan yang besar, kurangnya produktivitas, hilangnya hari kerja hingga terjadinya disabilitas.

Tujuan : menilai efektivitas terapi nonoperatif bila dibandingkan dengan terapi operatif pada pasien dengan CTS.

Metode : Penelusuran artikel dengan menggunakan Pubmed dan Google Scholar dan menggunakan kriteria inklusi dan eksklusi yang telah ditentukan sebelumnya. Hasil pencarian artikel tersebut kemudian dilakukan telaah dengan menggunakan kriteria penilaian validitas, tingkat pentingnya hasil yang didapat pada penelitian tersebut, dan kemamputerapan.

Hasil : Studi dalam systematic review ini masih mencakup studi yang sedikit dan sangat heterogen dengan outcomes yang bervariasi sehingga secara clinical efficacy belum dapat diyakini bahwa salah satu intervensi lebih baik yang lainnya pada tatalaksana CTS. Hasil gabungan dari analisis subgrup berupa peningkatan fungsi, peningkatan gejala, peningkatan parameter neurofisiologis, dan biaya perawatan pada waktu tindak lanjut yang berbeda menunjukkan bahwa perbedaan tidak signifikan secara statistik antara kedua intervensi. Perbedaan komplikasi dan efek samping secara statistik signifikan dan pengobatan non operatif mencapai hasil yang lebih baik daripada operatif (OR= 2,03, 95% CI= 1,28-3,22, p= 0,003).

Kesimpulan : Tatalaksana pada pasien Carpal Tunnel Syndrome baik dengan intervensi operatif maupun non operatif memiliki keuntungan masing- masing. Hasil intervensi dari segi peningkatan fungsi, perbaikan gejala dan parameter neurofisiologi serta pembiayaan tidak ada ada perbedaan yang signifikan antara keduanya. Intervensi operatif dapat dilakukan apabila perawatan non operatif gagal.

---

Background : Carpal Tunnel Syndrome (CTS) is the most common peripheral neuropathy in the upper extremities due to trapping or pinching of the median nerve in the carpal tunnel. In workers it is often caused by repetitive movements with flexion and extension on the wrist area, tight grasping movements, vibration. CTS cases are musculoskeletal disorders of the upper extremities with the most expensive health financing in the United States. In addition, it also causes loss of work days that exceed other occupational diseases other than fractures. CTS also results in large compensation expenditures, lack of productivity to disability.

Objective: to assess the effectiveness of nonoperative therapy when compared with operative therapy in patients with CTS.

Methods: Searching the articles by using Pubmed and Google Scholar as well as inclution and exclution criteria predetermined, articles were than performed using the assesment criteria of validity, importance, and ability applied

Results: The studies in this systematic review still include few and very heterogeneous studies with varying outcomes so that clinical efficacy cannot yet be believed that one of the other interventions is better in the management of CTS. The combined results from the subgroup analysis of improved function, improved symptoms, increased neurophysiological parameters, and treatment costs at different follow up times showed that the difference was not statistically significant between the 2 interventions. The difference in complications and side effects was statistically significant and nonoperative treatment achieved better results than operative (OR= 2.03, 95% CI= 1.28-3.22, p= 0.003).

Conclusion: The management of Carpal Tunnel Syndrome patients with both operative and non-operative interventions has their respective advantages. The results of the intervention in terms of improved function, improvement of symptoms and neurophysiological parameters and financing there is no significant difference between the two. Operative intervention can be done if non-operative care fails.

"

"Buku yang berjudul "The merck manual of diagnosis and theraphy" ini merupakan sebuah kamus tentang penyakit dan obat-obatan."