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"Molecular and translational vascular medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine. The text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis. Furthermore, it covers new areas of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms. Lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. All chapters are written by established experts in their fields, including pathologists, cardiovascular surgeons, and internists as well as translational biomedical researchers in a wide range of disciplines. While comprehensive, the material is presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases."

"This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders."

"This book provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational cardiology : molecular basis of cardiac metabolism, cardiac remodeling, translational therapies and imaging techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines."

"This concise and accessible systems-based text provides an integrated overview which considers both the basic sciences and clinical applications of the cardiovascular system. A general introduction to the cardiovascular system is followed by anatomy and histology, blood and body fluids, biochemistry and excitation-contraction coupling, form and function, integration and regulation, and pathology and therapeutics. The Cardiovascular System at a Glance is a perfect introduction and revision aid to understanding the heart and circulation and now also features: an extended section of self-assessment clinical cases to aid revision and illustrate clinical relevance; up-to-date information on pharmacology of the cardiovascular system; expanded material on history and examination and increased detlail on ECG of arrhythmias; and highly visual colour presentation."."The third edition of The Cardiovascular System at a Glance is an ideal resource for medical students, whilst students of other health professions and specialist cardiology nurses will also find it invaluable. Examination candidates who need an authoritative yet concise guide to the cardiovascular system will find it extremely useful"

"Triclustering digunakan untuk mengelompokkan data tiga dimensi secara simultan. Metode triclustering yang digunakan pada penelitian ini adalah gabungan 𝛿-Trimax dengan Fuzzy Cuckoo search (FCS) berdasarkan Lévy Flight. Data yang digunakan adalah data ekspresi gen dari proses diferensiasi human induced pluripoten stem cell (HiPSC) pada penderita penyakit jantung. Tahap awal adalah mencari populasi solusi tricluster homogen menggunakan metode 𝛿-Trimax. Penentuan nilai skala 𝛿 untuk menjalankan algoritma pada tahap populasi awal dilakukan menggunakan metode silhouette coefficient. Algoritma 𝛿-Trimax yang digunakan pada penelitian ini adalah algoritma Muliple Nodes Deletions dan Single Node Deletions. Tricluster yang didapatkan dari tahap 𝛿- Trimax selanjutnya akan dioptimasi menggunakan metode Fuzzy Cuckoo search berdasarkan Lévy Flight. Solusi tricluster yang berpotensi meningkatkan nilai fungsi objektif akan diganti menggunakan local random walk. Kumpulan tricluster yang terbentuk dari tahap optimasi akan dievaluasi menggunakan metode Tricluster Quality Index (TQI). Solusi tricluster terbaik yang diterapkan pada dataset tiga dimensi penyakit jantung didapatkan dari penggunaan nilai skala 𝛿 = 0,026 dan 𝜃 = 1,7. Solusi tricluster terbaik dianalisis lebih lanjut menggunakan Gene Ontology (GO) untuk menjelaskan keterkaitan gen-gen terhadap proses biologis, fungsi molekuler, dan komponen seluler.

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Triclustering is used to group three-dimensional data simultaneously. The triclustering method used in this research is a combination of δ-Trimax with Fuzzy Cuckoo search (FCS) based on Lévy Flight. The threedimensional data used is gene expression data from the human induced pluripotent stem cell (HiPSC) differentiation process in heart disease sufferers. The initial stage finds a homogeneous population of tricluster solutions using the δ-Trimax method. Determining the δ scale value for running the algorithm at the initial population stage is carried out using the silhouette coefficient method. The δ-Trimax algorithm used in this research is the Multiple Nodes Deletions and Single Node Deletions algorithms. The tricluster obtained from the δ-Trimax stage will then be optimized using the Fuzzy Cuckoo search method based on Lévy Flight. The tricluster solution which has the potential to increase the objective function value will be replaced using a local random walk. The tricluster collection formed from the optimization stage will be evaluated using the Tricluster Quality Index (TQI) method. The best tricluster solution applied to a three-dimensional heart disease dataset was obtained from using scale values δ = 0,026 and θ = 1,7. The best tricluster solution was further analyzed using Gene Ontology (GO) to explain the relationship of genes to biological processes, molecular functions, and cellular components.

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"Perawat spesialis kardiovaskuler berperan dalam praktik keperawatan berupa pemberi asuhan keperawatan tingkat lanjut, melakukan pembuktian ilmiah keperawatan dan agen pembaharu. Asuhan keperawatan dilakukan pada kasus pasien post operasi bedah jantung MVR (Mitral Valve Replacement) dan 30 pasien gangguan sistem kardiovaskuler dengan pendekatan model konservasi Levine. Model konservasi Levine efektif digunakan pada pasien dengan gangguan sistem kardiovaskuler. Evidence based nursing dilakukan dengan menerapkan edukasi berdasarkan kebutuhan pasien Acute Coronary Syndrome (ACS) untuk menurunkan kecemasan dengan hasil yang signifikan (p value 0,000). Proyek inovasi menerapkan format handover dengan metode SBAR (Situation, Background, Assessment, Recommendation).

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Cardiovascular specialist nurses play a role in nursing practice in the form of advanced nursing care providers, scientific proof of nursing and change agents. Nursing care is performed in the case of postoperative heart surgery patients MVR (Mitral Valve Replacement) and 30 patients with cardiovascular system disorder with Levine conservation model approach. Levine's conservation model is effective in patients with cardiovascular system disorders. Evidence-based nursing is done by applying education based on patient Acute Coronary Syndrome (ACS) needs of learning to decrease anxiety with significant results (p value 0,000). The innovation project applies the handover format using the SBAR (Situation, Background, Assessment, Recommendation) method."

"This book presents many of the major, relevant advances in molecular pathology that are occurring in the field of pediatric oncology and will serve as a useful overview for resident and attending physicians as well as scientists interested in understanding the molecular pathology of pediatric cancer in the context of clinical medicine. Chapters are based upon organ systems, and each is written by an expert or pair of experts in their field with subspecialty training and extensive clinical experience. Each chapter describes a variable number of tumors and includes an overview of the classification system and clinicopathological characteristics of each tumor. This is followed by a discussion of the molecular pathology relevant to a specific tumor, including specific molecular markers of the tumors, methods used for diagnosis or clinical management, clinical significance of the markers, and if appropriate, a description or discussion of current activities in translational research or issues that need to be addressed in the future. "

"Practical, didactic format designed to deliver point-of-care information to practitioners of cardiology. Highly illustrated with schematics and useful clinical figures, this will be an essential reference to all outpatient cardiology procedures."