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"ABSTRAKPengukuran VO2max secara langsung memang menghasilkan data yang akurat dan dapat dipercaya tetapi umumnya memerlukan waktu lebih banyak, peralatan yang mahal serta tenaga pelaksana terlatih. Penelitian sebelumnya telah berhasil mengembangkan model prediksi khusus untuk anak-anak dari etnis Jawa berdasarkan jenis kelamin, denyut nadi dan waktu tempuh berjalan.Penelitian ini bertujuan untuk mengembangkan model prediksi yang cocok bagi kelompok usia remaja dengan prediktor jenis kelamin, status gizi (IMT/U dan PLT), aktivitas fisik dan asupan gizi. Penelitian dilakukan pada 78 remaja laki-laki dan 114 remaja perempuan dengan rata-rata usia 16,19±0,5 tahun. Nilai estimasi VO2max diukur berdasarkan tes lari 1 mil, jenis kelamin, IMT/U ditentukan berdasarkan pengukuran berat badan dan tinggi badan, PLT diukur dengan BIA, aktivitas fisik diketahui melalui pengisian kuesioner, dan asupan gizi dihitung dengan menggunakan metode food record 3 hari. Terdapat hubungan yang bermakna antara jenis kelamin, IMT/U, persen lemak tubuh, aktivitas fisik, seluruh asupan zat gizi makro (energi, karbohidrat, protein, lemak) dan beberapa asupan zat gizi mikro (vitamin B2, vitamin B6 dan seng) dengan nilai estimasi VO2max. Model prediksi non latihan dibentuk melalui analisis multi regresi linier VO2max= 40,7 + 3,1 JK - 2,5 IMT/U - 0,08 PLT + 0,4 AF - 0,004 P + 0,001 A - 1,76 B6 - 0,2 B12 + 0,5 Zn. Untuk meningkatkan nilai VO2max pada remaja, sekolah direkomendasikan untuk mengimplementasikan program TOP yang kegiatannya berfok us pada kegiatan pengendalian berat badan, peningkatan aktivitas fisik, dan promosi asupan yang bergizi seimbang.

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ABSTRACTA direct measurement on maximal oxygen uptake (VO2max) provides accurate and reliable data but requires more time, costly aquipment and trained personnel. Previous research has developed a VO2max prediction model special for Javanese children using sex, heart rate and walk time.The purpose of this study was to investigate the use of gender, nutritional status (body mass index for age and percent fat), physical activity level, and dietary intake in another VO2max prediction model for adolescent. The design study was a cross sectional one. Subjects were 78 male and 114 female wih a mean age of 16,19±0,5 years. Estimated VO2max was measured from one mile run test; sex; BMI for age was calculated from measured height and weight, percent fat was assessed by BIA, self report physical activity was assessed by PAQ-A and 3 day food records were used to calculate the average dietary intake. Male students (42,45 ml/kg/min) had significantly higher estimated VO2max than female (38,74 ml/kg/min). There were significant correlations between sex, BMI for age, percent fat, physical activity, all macronutrient intake (energi, carbohydrat, protein, and fat) and some micronutrient intake (vitamin B2, vitamin B6 and zinc) with estimated VO2max. The non-exercise prediction model was developed by a multiple regression analysis: VO2max= 40,7+3,1 JK-2,5 IMT/U-0,08 PLT + 0,4 AF-0,004 P + 0,001 A-1,76 B6-0,2 B12+0,5 Zn. In order to improve adolescent?s VO2max, school was recomended to implement TOP program focused on weight management, increased physical activity and promoted adequate dietary intake."

"ABSTRAK Penelitian mengenai asupan serat pangan dan air dan kejadian konstipasi pada remaja masih belum banyak Tujuan penelitian ini untuk mendapatkan profil jumlah asupan serat pangan dan air pada remaja serta hubungan antara asupan serat pangan dan air terhadap pola buang air besar konsistensi tinja dan konstipasi Studi potong lintang dilakukan pada 120 siswa SMU berusia 15 17 tahun dilakukan selama Oktober Desember 2015 Data jumlah asupan energi karbohidrat protein lemak air dan serat bahan makanan dan minuman dikumpulkan dengan menggunakan food record form selama 2x24 jam dan food frequency questionnaire FFQ Subjek terdiri dari 82 anak perempuan 68 3 dan 38 anak lelaki 31 7 sebagian besar dengan gizi baik dan perawakan normal Hanya dua subjek yang mengalami konstipasi Median asupan energi protein lemak dan karbohidrat air dan serat berturut turut sebanyak 1419 3 kalori 54 6 gram 48 4 gram dan 183 2 gram 2079 mL dan 5 1 gram Jumlah asupan energi karbohidrat dan air subjek lelaki secara bermakna lebih tinggi dibandingkan perempuan Tidak didapatkan hubungan bermakna antara asupan serat pangan dan air dengan kejadian konstipasi Data yang didapat menunjukkan jumlah asupan serat pangan remaja usia 15 17 tahun di bawah AKG yang dianjurkan Sebaliknya jumlah asupan air sesuai dengan AKG yang dianjurkan Data yang didapat diharapkan dapat dipergunakan sebagai dasar untuk penelitian selanjutnya ABSTRACT Indonesian children and adolescent are alleged not to consume sufficient fiber and water while studies show fiber and water affect defecation profile This cross sectional study records the amount of fiber and water intake of Indonesian adolescents aged 15 17 years and their defecation pattern Subjects are 120 SMU 68 students aged 15 17 years 82 girls and 38 boys The study was conducted between October and December 2015 We attempt to find any correlation between fiber and water intake and defecation profile Most of the subjects were well nourished and normal stature Median water and fiber intake were 2079 mL and 5 1 grams The median of energy protein fats and carbohydrates intake were 1419 3 calories 54 6 grams 48 4 grams and 183 2 grams consecutively Only two subjects who experienced constipation About 49 subjects had abdominal pain according to Rome III Criteria We found there is no significant association between dietary fiber intake and water consumption and constipation However we feel that future study should be carried out to encrich our data in this field ;Indonesian children and adolescent are alleged not to consume sufficient fiber and water while studies show fiber and water affect defecation profile This cross sectional study records the amount of fiber and water intake of Indonesian adolescents aged 15 17 years and their defecation pattern Subjects are 120 SMU 68 students aged 15 17 years 82 girls and 38 boys The study was conducted between October and December 2015 We attempt to find any correlation between fiber and water intake and defecation profile Most of the subjects were well nourished and normal stature Median water and fiber intake were 2079 mL and 5 1 grams The median of energy protein fats and carbohydrates intake were 1419 3 calories 54 6 grams 48 4 grams and 183 2 grams consecutively Only two subjects who experienced constipation About 49 subjects had abdominal pain according to Rome III Criteria We found there is no significant association between dietary fiber intake and water consumption and constipation However we feel that future study should be carried out to encrich our data in this field ;Indonesian children and adolescent are alleged not to consume sufficient fiber and water while studies show fiber and water affect defecation profile This cross sectional study records the amount of fiber and water intake of Indonesian adolescents aged 15 17 years and their defecation pattern Subjects are 120 SMU 68 students aged 15 17 years 82 girls and 38 boys The study was conducted between October and December 2015 We attempt to find any correlation between fiber and water intake and defecation profile Most of the subjects were well nourished and normal stature Median water and fiber intake were 2079 mL and 5 1 grams The median of energy protein fats and carbohydrates intake were 1419 3 calories 54 6 grams 48 4 grams and 183 2 grams consecutively Only two subjects who experienced constipation About 49 subjects had abdominal pain according to Rome III Criteria We found there is no significant association between dietary fiber intake and water consumption and constipation However we feel that future study should be carried out to encrich our data in this field "

"Prevalensi obesitas pada remaja usia 16-18 tahun di Indonesia terus meningkat dalam lima tahun terakhir, begitu pula dengan prevalensi depresi pada remaja. Remaja rentan mengalami ketidakstabilan psikologis sehingga rentan mengalami depresi. Penelitian ini bertujuan untuk mengetahui hubungan antara depresi dengan obesitas pada remaja usia 16 - 18 tahun di Indonesia. Penelitian ini menggunakan desain studi cross-sectional dengan data sekunder yaitu Riskesdas 2018. Sampel penelitian ini adalah remaja usia 16 - 18 tahun di Indonesia yang menjadi sampel Riskesdas sebanyak 43010 remaja. Hasil penelitian ini menunjukkan bahwa 4,3% remaja mengalami obesitas. Depresi secara signifikan berhubungan dengan obesitas (p = 0,009). Hasil analisis multivariat menunjukkan remaja yang depresi 1,28 kali (95% CI; 1,068 – 1,535) lebih memungkinkan untuk menjadi obesitas setelah mengontrol konsumsi makanan manis, minuman manis, makanan berlemak, makanan instan, konsumsi sayur, aktivitas fisik, status merokok, dan konsumsi alkohol. Disimpulkan terdapat hubungan antara depresi dengan obesitas pada remaja usia 16-18 tahun di Indonesia.

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ABSTRACTThe prevalence of obesity among adolescence in Indonesia has increased in the last five years, as well as the prevalence of depression. Adolescences are prone to experiencing psychological imbalance so they are prone to depression. The aim of this study is to analyze the association between depression and obesity among 16-18 years old adolescences in Indonesia. This study used a cross-sectional design and used secondary data from Riskesdas 2018. The sample in this study is 16-18 years old adolescences who were taken as the sample of Riskesdas 2018. The study shows that 4,3% of adolescences are obese. Depression is significantly associated with obesity (p=0,009) and depressed adolescences are 1,28 times (95%CI;1,068–1,535) more likely to become obese after controlled by consumption of sugary food, sweetened beverages, fatty food, instant food, consumption of vegetable, physical activity, smoking habit, and alcohol consumption. To conclude, there is an association between depression and obesity among 16-18 years old adolescences in Indonesia."

"Latar belakang: Lupus eritematosus sistemik (LES) merupakan penyakit autoimun sistemik yang 10-20% kasusnya memiliki awitan sejak masa kanak. Kesintasan anak dengan LES di negara maju maupun berkembang jauh meningkat sejak beberapa dekade terakhir. Meskipun kesintasannya meningkat, tidak semua anak dan remaja LES dapat memasuki masa dewasa dengan baik. Layanan transisi remaja merupakan jembatan penghubung antara layanan kesehatan anak dan dewasa yang mulai banyak dikembangkan untuk remaja dengan kebutuhan medis khusus seperti LES.Metode: Studi pre-eksperimental pada remaja LES berusia 15 tahun hingga 17 tahun 6 bulan dilakukan di RSUPNCM dalam kurun waktu antara Desember 2022 hingga Mei 2023. Dalam studi ini seluruh subyek diikutkan dalam modul transisi remaja yang kegiatannya dilakukan secara daring maupun luring. Kegiatan daring meliputi 3 kali pemaparan materi dan diskusi interaktif dengan tema LES, masa remaja, dan layanan kesehatan di klinik dewasa. Kegiatan luring dilakukan melalui bermain peran menyerupai suasana saat melakukan kunjungan mandiri di layanan kesehatan dewasa yang dilakukan pada akhir penelitian. Luaran modul transisi dinilai dengan membandingkan rerata skor TRAQ 6.0 Bahasa Indonesia sebelum dan sesudah mengikuti modul transisi.Hasil: Terdapat 36 remaja LES yang mengikuti modul transisi, namun hanya 32 subyek yang mengikuti ≥75% kegiatan. Rerata skor TRAQ 6.0 Bahasa Indonesia sebelum mengikuti modul adalah 3,4 (0,6). Rerata tersebut meningkat menjadi 3,8 (0,6) setelah mengikuti modul (p=0.001). Tidak ada hubungan antara lama sakit, derajat aktivitas penyakit, dan kunjungan mandiri terhadap skor TRAQ 6.0 Bahasa Indonesia sebelum mengikuti modul transisi. Simpulan: Modul transisi remaja terbukti dapat meningkatkan kesiapan transisi remaja dengan LES berusia 15-17 tahun.

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Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease in which 10-20% of cases have an onset in childhood. The survival of children with SLE in both developed and developing countries has increased greatly in the last few decades. Although survival has increased, not all children and adolescents with SLE can enter adulthood well. Adolescent transition services are a bridge between child and adult health services which have begun to be developed for adolescents with special medical needs such as SLE.

Methods: The pre-experimental study on LES adolescents aged 15 to 17 years 6 months was conducted at Cipto Mangunkusumo General Hospital from December 2022 to May 2023. In this study, all subjects were included in the adolescent transition module, whose activities were carried out both online and offline. Online activities include 3 presentations of material and interactive discussions on the themes of LES, adolescence, and health services in adult clinics. Offline activities are carried out through role playing, resembling the atmosphere during independent visits to adult health services carried out at the end of the study. The main outcome of the transition module was assessed by comparing the average Indonesian TRAQ 6.0 score before and after participating in the transition module.

Results: There were 36 LES adolescents who took part in the transition module, but only 32 subjects took ≥75% of the activities. The average Indonesian TRAQ 6.0 score before taking the module was 3.4 (0.6). The mean increased to 3.8 (0.6) after participating in the module (p=0.001). There is no relationship between disease duration, degree of disease activity, and independent visits to the Indonesian TRAQ 6.0 score before joining the transition module.

Conclusion: The transition module has been proven to increasing transition readiness of adolescents aged 15 to 17 years with SLE."

"Hipertensi remaja masih menjadi masalah bagi kesehatan karena dapat meningkatkan angka kesakitan dan kematian akibat penyakit kardiovaskular di masa dewasa. Salah satu faktor risiko hipertensi remaja adalah overweight. Terdapat peningkatan prevalensi overweight pada remaja umur 16-18 tahun di Indonesia berdasarkan Riskesdas tahun 2007-2013 sebesar 5,7% menjadi 6,7% Tujuan penelitian ini adalah mengetahui hubungan overweight dengan hipertensi remaja usia 15-17 tahun di Indonesia berdasarkan data IFLS V Tahun 2014. Desain Penelitian ini adalah studi cross sectional dengan menggunakan data sekunder dari IFLS V Tahun 2014. Analisis data yang digunakan adalah Regresi Logistik. Hasil analisis menunjukkan remaja dengan overweight berpeluang 1,530 kali (95% CI; 1,080-2,166) dibandingkan remaja tidak overweight setelah dikendalikan oleh jenis kelamin. Remaja terutama remaja laki-laki dapat meningkatkan aktivitas fisik (jalan cepat dan lari) untuk mencegah overweight dan hipertensi.

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Adolescents hypertension is still become a problem for health, because it can increase the number of mortality and morbidity from cardiovascular disease in adulthood. Overweight has become one of the risk factors of it. There is increasing prevalence of overweight in adolescents of aged 16-18 in Indonesia. Based on Riskesdas, there is a growing of adolescents at the aged of 16-18 in Indonesia between 2007-2013, its around 5,7% and 6,7%. The aim of this study is to find out the relation of overweight and adolescents hypertension at the aged of 15-17 based on IFLS V data in 2014.

The design of this study is using cross sectional secondary data of IFLS V 2014 with logistic regression are used for data analysis. The analysis showed that adolescents with overweight had a POR 1,530 times (95% CI 1.880-2.166) compared to un-overweight (normal-weight) adolescents after being control by gender. The boys have advantage to increasing of physical activity (by running or brisk walking) to prevent from overweight and hypertension."

"ABSTRAKLatar belakang: Thalassemia merupakan suatu penyakit gen tunggal yang disebabkan oleh kerusakan pada gen dalam mengontrol produksi protein sehingga sel darah merah akan mudah pecah dan pengikatan oksigen terganggu. Hal ini akan memicu terjadinya anemia dan membutuhkan transfusi darah secara rutin dan seumur hidup. Transfusi darah rutin menyebabkan terjadinya akumulasi besi yang memicu beberapa komplikasi, salah satunya adalah gangguan pada fungsi pankreas. Tujuan: Untuk mengetahui hubungan antara profil besi dengan gangguan fungsi pankreas berupa diabetes mellitus dan gangguan toleransi glukosa pada subjek thalassemia mayor. Metode: Desain potong-lintang pada 79 subjek thalassemia mayor di Pusat Thalassemia RS Cipto Mangunkusumo Jakarta. Hasil: Dua 2,53 subjek mengalami gangguan toleransi glukosa dan 77 97,47 subjek dengan nilai toleransi glukosa normal. Nilai median feritin serum pada kelompok gangguan toleransi glukosa yakni 5595,5 2062,0-9199,0 ng/mL sedangkan yang tidak mengalami gangguan toleransi glukosa yakni 3309,0 487,0-11247,0 ng/mL p= 0,574 . Nilai median saturasi transferin pada subjek gangguan toleransi glukosa yakni 76 52-100 sedangkan yang tidak mengalami gangguan toleransi glukosa yakni 89 11-100 p= 0,827 . Kesimpulan: Tidak didapatkan adanya hubungan yang signifikan antara kadar feritin serum dan saturasi transferin terhadap gangguan fungsi pankreas.

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ABSTRACTBackground Thalassemia is a single gene disease that is caused by defect on gene which controls the protein production that eventually leads to red blood cell lysis and defect on oxygen binding capacity. Therefore, the patient needs regular blood transfusion during his lifetime. Regular blood transfusion causes iron accumulation that leads to complications such as defect on pancreas function. Aim To know the association between iron profile and defect on pancreas function such as diabetes mellitus and glucose intolerance in major thallassemia subjects. Methods Cross sectional design on 79 major thalassemia subjects in Thalassemia Center of RS Cipto Mangunkusumo, Jakarta. Results Two 2.53 subjects were glucose intolerant and 77 97,47 subject has a normal blood glucose. Median value of serum ferritin level in glucose intolerant subjects was 5595.5 2062,0 9199,0 ng mL meanwhile the median value of serum ferritin level in normal glucose level subjects was 3309.0 487,0 11247,0 ng mL p 0.574 . The median value of transferrin saturation in glucose intolerant patients is 76 52 100 meanwhile the median value of tranferrin saturation level in normal glucose level subjects is 89 11 100 p 0,827 . Conclusion There is no significant association between serum ferritin level and transferrin saturation and defect of pancreas function."

"Defisiensi besi adalah defisiensi mikronutrien yang paling sering ditemui. Jika tidak diobati, dapat menyebabkan anemia defisiensi besi dan gangguan kognitif, terutama pada anak usia sekolah, yang ireversibel. Diagnosis defisiensi besi rumit, tidak praktis, dan mahal. Organisasi AAP merekomendasikan RET-He sebagai pemeriksaan laboratorium untuk skrining defisiensi besi. Tujuan penelitian adalah untuk mencari nilai batasan RET-He untuk skrining status besi pada anak usia 6 – 18 tahun. Studi ini merupakan studi potong lintang terhadap 207 anak sehat usia 6 - 18 tahun di Indonesia. Penelitian ini mencari nilai batasan RET-He untuk skrining status besi, kemudian dibandingkan dengan hemoglobin, mean corpuscular volume, feritin, dan saturasi transferin. Kurva ROC dikerjakan untuk menentukan nilai batasan RET-He untuk skrining status besi dengan menggunakan IBM SPSS versi 22. Pemeriksaan RET-He mendapatkan nilai batasan ≤ 30,3 pg (sensitivitas 100%, spesifisitas 19,7%, NDN 100%, NDP 5,4%) untuk skrining deplesi besi; nilai batasan RET-He ≤ 28,9 pg (sensitivitas 78,9%, spesifisitas 56,2%, NDN 92,2%, dan NDP 28,9%) untuk defisiensi besi; dan nilai batasan RET-He ≤ 27 pg (sensitivitas 75%, spesifisitas 80%, NDN 98,1%, dan NDP 18,7%) untuk anemia defisiensi besi. Peneliti menarik kesimpulan bahwa RET-He dapat digunakan sebagai parameter skrining defisiensi besi dengan nilai batasan ≤ 28,9 pg. Skrining untuk anemia defisiensi besi dapat menggunakan RET-He dengan nilai batasan ≤ 27 pg, namun harus dilakukan dengan parameter lain, seperti Hb. Pemeriksaan RET-He dengan nilai batasan ≤ 30,3 pg tidak dapat digunakan untuk skrining deplesi besi.

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Iron deficiency (ID) is the most common micronutrient deficiency in the world. Left untreated, ID will lead to iron deficiency anemia (IDA) and other irreversible consequences. Screening iron deficiency is complex, impractical, and expensive. The AAP recommended RET-He as an alternative laboratory examination to screen ID. The objective is to find RET-He cut-off value to screen for iron status in healthy children, aged 6 – 18 years old. This study is a cross-sectional study of 207 children aged 6 – 18 years old in Indonesia. RET-He was compared with hemoglobin, mean corpuscular volume, ferritin to assess iron status in children. Receiver operating curve was performed to determine the optimal cut-off value for RET-He using IBM SPSS 22. Reticulocyte hemoglobin equivalent with cut-off value ≤ 30.3 pg was established to screen iron depletion (100% sensitivity, 19.7% specificity, 100% NPV, 5.4% PPV); meanwhile RET-He ≤ 28.9 pg to screen iron deficiency (78.9% sensitivity, 56.2% specificity, 92.2% NPV, 28.9% PPV); and RET-He ≤ 27 pg to screen IDA (75% sensitivity, 80% specificity, 98.1% NPV, 18.7% PPV). The researcher concluded that RET-He can be used as an iron deficiency screening parameter with a cut-off value ≤ 28.9 pg. Screening for IDA with RET-He ≤ 27 pg need to be done with other parameters, such as Hb. RET-He ≤ 30.3 pg cannot be used for iron depletion."