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"99mTc-sestamibi is a single-photon emission computed tomography (SPECT) radiotracer that is widely used for the imaging of myocardial perfusion, as well as a variety of malignant and benign diseases. 99mTc-Sestamibi. Clinical applications provides a detailed and informative overview of almost all the oncologic and non-oncologic applications of 99mTc-sestamibi SPECT, including several relatively rare indications. Different disease-related protocols for 99mTc-sestamibi SPECT are presented, and for each disease a comprehensive summary of the relevant pathology and epidemiology is provided. Throughout, there is a strong emphasis on the practical aspects of use of this popular tracer, including instructions for the preparation of several commercially available tracer kits. Clinical practitioners will find this book to be an invaluable guide to the application and benefits of 99mTc-sestamibi SPECT in both the inpatient and the outpatient setting."

"In this book how cosmogenic radionuclides can be used to trace and to reconstruct the history of a large variety of processes. They discuss the way in which cosmogenic radionuclides can assist in the quantification of complex processes in the present-day environment. "

"The rapid advances in CCT technology, the advent of new clinical applications, and the acquisition of data on prognostic value are just some of the reasons for the publication of this new edition of Clinical Applications of Cardiac CT, little more than 3 years after the first edition appeared. The text has been extensively revised and updated to reflect current knowledge and practice, and the structure and layout of the educational content have also been improved. The imaging targets, semeiology, technique, and clinical applications of CCT are all covered in detail, and in addition relevant information is provided on epidemiology, clinical assessment, and the role of other diagnostic modalities. This book will prove an invaluable tool for radiologists and cardiologists alike."

"Multidetector-row computed tomography (MDCT) has become a fundamental imaging technique for the study of many anatomical districts in different clinical situations, as it provides a fast, reliable, and accurate simultaneous evaluation of different organs, including parenchyma, hollow viscera, vessels, and bony structures. It has also equipped the radiologist with the ability to explore areas that in the last decade were largely ignored by CT, especially the coronary arteries and the colon, and to limit invasive diagnostic tests (e.g., catheter angiography) to those cases in which interventional procedures are required.The examination quality and the consequent diagnostic accuracy of MDCT are the results of an optimized study technique, which nonetheless needs to be adapted to the particular clinical situation of the patient, while bearing in mind the radiation exposure. Another fundamental parameter in the optimization of MDCT is the protocol for the intravenous injection of iodinated contrast material; in these studies, multiple variables, some modifiable by the operator and others patient-dependent, must be considered based on the aims of maximizing arterial and venous enhancements whilst minimizing the dose of iodine injected, saving money, and increasing patient safety.Through the presentation of cases addressing different anatomical regions and various clinical indications, including emergency and neuro-imaging, this volume seeks to provide the general radiologist and trainee specialist with a guide to the main study protocols to be implemented in order to optimize examination quality and, consequently, facilitate the diagnostic process."

"Technology and principles using cone beam computed tomography / Matthew Jacobson -- The nature of ionizing radiation and the risks from maxillofacial cone beam computed tomography / Sanjay M. Mallya and Stuart C. White -- Diagnosis of jaw pathologies using cone beam computed tomography / Sharon Brooks -- Diagnosis of sinus pathologies using cone beam computed tomography / Aaron Miracle and Christian GuÌ?ldner -- Orthodontic and orthognathic planning using cone beam computed tomography / Lucia H.S. Cevidanes, Martin Styner, Beatriz Paniagua, JoaÌ?o Roberto Gonçalves -- Three-dimensional planning in maxillofacial reconstruction of large defects using cone beam computed tomography / Rutger Schepers, Gerry M. Raghoebar, Lars U. Lahoda, Harry Reintsema, Arjan Vissink, and Max J. Witjes -- Implant planning using cone beam computed tomography / David Sarment -- CAD/CAM surgical guidance using cone beam computed tomography / George A. Mandelaris and Alan L. Rosenfeld -- Assessment of the airway and supporting structures using cone beam computed tomography / David D. Hatcher -- Endodontics using cone beam computed tomography / Martin D. Levin -- Periodontal disease using cone beam computer tomography / Bart Vandenbergh"

"Over the past decade, PET-CT has achieved great success owing to its ability to simultaneously image structure and function, and show how the two are related. More recently, PET-MRI has also been developed, and it represents an exciting novel option that promises to have applications in oncology as well as neurology. The first part of this book discusses the basics of these dual-modality techniques, including the scanners themselves, radiotracers, scan performance, quantitation, and scan interpretation. As a result, the reader will learn how to perform the techniques to maximum benefit. The second part of the book then presents in detail the PET-CT and PET-MRI findings in cancers of the different body systems. The final two chapters address the use of PET/CT in radiotherapy planning and examine areas of controversy. The authors are world-renowned experts from North America, Europe, and Australia, and the lucid text is complemented by numerous high-quality illustrations."

"The horizons of sophisticated imaging have expanded with the use of combined positron emission tomography (PET) and computed tomography (CT). PET-CT has revolutionized medical imaging by adding anatomic localization to functional imaging, thus providing physicians with information that is vital for the accurate diagnosis and treatment of pathologies. Since the integration of PET and CT several years ago, PET/CT procedures are now routine at leading medical centers throughout the world. This has increased the importance of nuclear medicine physicians acquiring a broad knowledge in sectional anatomy for image interpretation. The Atlas of Sectional Radiological Anatomy for PET/CT is a user-friendly guide presenting high-resolution, full-color images of anatomical detail and focuses solely on normal FDG distribution throughout the head & neck, thorax, abdomen, and pelvis, the primary sites for cancer detection and treatment through PET/CT."

""The book offers a comprehensive and user-oriented description of the theoretical and technical system fundamentals of computed tomography (CT) for a wide readership, from conventional single-slice acquisitions to volume acquisition with multi-slice and cone-beam spiral CT. It covers in detail all characteristic parameters relevant for image quality and all performance features significant for clinical application. Readers will thus be informed how to use a CT system to an optimum depending on the different diagnostic requirements. This includes a detailed discussion about the dose required and about dose measurements as well as how to reduce dose in CT. All considerations pay special attention to spiral CT and to new developments towards advanced multi-slice and cone-beam CT. For the third edition most of the contents have been updated and latest topics like dual source CT, dual energy CT, flat detector CT and interventional CT have been added. The enclosed CD-ROM again offers copies of all figures in the book and attractive case studies, including many examples from the most recent 64-slice acquisitions, and interactive exercises for image viewing and manipulation. This book is intended for all those who work daily, regularly or even only occasionally with CT: physicians, radiographers, engineers, technicians and physicists. A glossary describes all the important technical terms in alphabetical order. The enclosed DVD again offers attractive case studies, including many examples from the most recent 64-slice acquisitions, and interactive exercises for image viewing and manipulation"--Back cover."

"PET scanner dikenal secara luas dalam pencitraan klinis untuk menentukan abnormalitas deteksi lesi kecil. Dalam studi ini, dilakukan evaluasi deteksi objek lesi menggunakan solid fantom in-house. Pengukuran dilakukan dengan menggunakan phantoms in-house dalam bentuk silinder lingkaran dan elips dengan objek lesi berdiameter 6 mm dan konsentrasi aktivitas FDG yang bervariasi. Lebih lanjut, dilakukan pula pengukuran objek lesi  dengan ukuran 6-, 8-, 11-, 16-, and 21 mm yang berada dalam phantoms silinder elips dengan material ekuivalen paru dan liver, berturut-turut dengan ukuran major dan minor axis, (33 × 18 cm) dan (28×20 cm). Objek lesi dilakukan variasi posisi secara sejajar dan melingkar. Evaluasi citra PET dilakukan perhitungan untuk menentukan Full Width Half Maximum (FWHM) berdasarkan protokol National Electrical Manufacturing Association (NEMA), dan selanjutnya menghitung Conversion Factor FWHM (CFh), serta menggunakan Fitting Gaussian. CFh merupakan rasio antara ukuran objek aktual dan citra FWHM. FWHM dalam sumbu x dan sumbu y berkisar antara 7,61 hingga 10,68 untuk 6 mm; 8,41 hingga 10,94 untuk 8 mm; 9,59 hingga 11,20 untuk 11 mm; 12,59 hingga 14,43 untuk 16 mm; 16,77 hingga 18,61 untuk 21 mm. Dengan hasil menunjukan CFh dipengaruhi oleh ukuran objek lesi di dalam phantom silinder elipse dengan material ekuivalen paru-paru dan hati yang. Citra PET  10 mm diperoleh nilai FCF  1.00 menunjukan ukuran objek sebenarnya lebih kecil dari ukuran citra. Citra PET hampir tidak mengalami perbesaran apabila citra PET mendekati 10 mm. Untuk citra PET 10 mm ditunjukan oleh nilai FCF  1.00, yang berarti ukuran objek sebenar lebih dari ukuran citra.

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PET scanner is widely known in clinical imaging to determine small lesions. We evaluated the detection of lesion object using solid-phantom in-house. Measurement was performed using in-house phantoms ellipse with carried out sizes of lesion object 6-, 8-, 11-, 16-, and 21 mm in lung and liver equivalent material. The lesion object was arranged in different position of parallel and circular.  Evaluation of PET image was calculated to determine the Full Width Half Maximum (FWHM) based on National Electrical Manufacturing Association (NEMA) protocol, and furthermore to calculate Conversion Factor FWHM (CFh), which represents the ratio between the size of the actual object and FWHM profile image.

The FWHMs in x-axis and y-axis were range 7.61 to 10.68 for 6 mm; 8.41 to 10.94 for 8 mm; 9.59 to 11.20 for 11 mm; 12.59 to 14.43 for 16 mm; 16.77 to 18.61 for 21 mm. With the result that the CFh was affected by the size of lesion object inside the ellipse cylinder phantom with lung and liver equivalent. PET image is size <10 mm obtained CFh value <1.00, it indicates that the actual object size is smaller than the image size. The PET image was barely enlarged if the PET image approaches 10 mm. PET images >10 mm was indicated by the CFh value >1.00, which means the object size was actually higher than the image size."

"Tujuan penelitian ini adalah untuk melakukan pengukuran CTDI dan dosis efektif pada 3 mesin CT dengan pengujian abdominal terhadap pasien pediatrik dan dewasa menggunakan phantom CT yang dibuat dan detector pensil CT serta electrometer RADCAL. Phantom CT dibuat berdasarkan standar US-FDA untuk CT. Pengujian Computed Tomography (CT) yang dilakukan menggunakan 2 CT phantom yang berbeda, diameter 32 cm (pasien dewasa) dan diameter 16 cm (pasien pediatrik). Pengukuran CTDI dan perhitungan dosis efektif radiasi menunjukkan bahwa terdapat dosis pasien pediatrik yang lebih tinggi signifikan dibandingkan dengan dosis pasien dewasa pada perlakuan yang sama. Hal ini menandakan pentingnya penentuan secara hati-hati parameter teknis scan dan justifikasi yang kuat terhadap penggunaan pengujian CT pada pasien pediatrik.

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A study has been performed to measure CTDI and effective dose on 3 CT machines pertinent to abdominal examination to adult and pediatric patients using fabricated CT phantom and RADCAL pencil detector and electrometer. The CT phantom was tailored according US-FDA standard. Computed tomographic (CT) examinations have been performed using two different CT phantoms, 32 cm (adult) and 16 cm (pediatric) diameter. Computed tomographic (CT) examinations and radiation effective dose showed significant higher pediatric dose as compared to adult patient dose at the same examinations. This indicates the importance of careful selection of technical scan parameters and strong justification of the use of CT examination on pediatric patient."