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"The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current methods and techniques. Each chapter was written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: In vitro mammalian cytogenetics tests Phototoxicity Carcinogenicity studies The pharmacogenomics of personalized medicine Bridging studies Toxicogenomics and toxicoproteomics Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This is a hands-on guide for pharmaceutical scientists involved in preclinical testing,enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin."

"Forensic professionals, often working through heavy caseloads, require quick and easy access to reliable sources of information to help interpret toxicology results. While several in-depth resources are available, they are often large, cumbersome, and contain more information than is needed. The Handbook of Forensic Toxicology for Medical Examiners is a concise handbook referencing the most common toxic substances and their levels of toxicity, making it an ideal text for quick confirmation in the field or in the lab." "The book begins by explaining the proper selection and submission of specimens for toxicological analysis. It describes the various types of specimens and identifies the cases for which these specimens would be most useful, providing instruction on proper collection. The author then explains the methodology involved in performing the specific tests." "The main section of the text consists of an alphabetical listing of nearly 300 toxic substances, including drugs of --abuse, poisons, prescription drugs, and over-the-counter medications. For each entry, the book provides the common brand names; classification; half life; volume of distribution; usual dosage; tables of toxicity in various samples, including blood, urine, and tissues; and other important information based on the extensive experience of the author. The text is heavily referenced with materials that are useful for preparation of courtroom testimony, and it contains supplemental appendices with information on acetylcholinesterase inhibitors, drugs that prolong the QT interval, pharmacogenetics, normal laboratory values, and conversion charts." "The busy forensic professional needs a concise handbook that provides critical information quickly without the need to wade through extraneous and inconsequential material. This volume offers an easy-to-use format that allows quick access to the most pertinent information, saving time and increasing accuracy." --Book Jacket."

"Buku yang berjudul "Handbook of emergency toxicology : a guide for the identification, diagnosis and treatment of poisoning" ini ditulis oleh Sidney Kaye. Buku ini merupakan sebuah buku panduan mengenai identifikasi dan diagnosa racun-racun."