Hasil Pencarian  ::  Simpan CSV :: Kembali

"Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atherosclerosis. There is a focus on both the "bad" and "good" cholesterol carriers, LDL and HDL. Adi Haber proceeds from basic findings in pure chemistry through biochemical and cell culture tests to in vivo examinations. The work in this thesis shows that corroles are highly efficient both for early and late treatment of atherosclerosis in animals. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases."

"

Aterosklerosis adalah fenomena penyempitan arteri karena penumpukan plak di dinding arteri sebagai akibat dari suatu pola hidup tidak sehat. Menurut pendekatan ilmu sosial, pola hidup yang salah dapat ditularkan kepada orang lain disekitarnya. Bentuk penanganan pasien aterosklerosis adalah melalui operasi bypass yang harus dilakukan oleh dokter spesialis dan di rumah sakit tertentu, yang keduanya memiliki jumlah yang terbatas. Jika jumlah pasien dengan komplikasi aterosklerosis terus bertambah, itu akan berdampak pada pengobatan yang tidak lagi optimal. Penelitian ini bertujuan untuk membangun model penyebaran aterosklerosis tanpa dan dengan mempertimbangkan pengaruh keterbatasan sumber daya rumah sakit, yang dikenal sebagai efek saturasi. Kedua model dibentuk dengan membagi kompartemen manusia dalam populasi yang rentan, terinfeksi aterosklerosis, dan penderita aterosklerosis yang menjalani pengobatan. Model-model yang telah dibangun kemudian dianalisis secara analitik dan numerik. Studi analitik dilakukan untuk menemukan dan menganalisis titik keseimbangan, menentukan bilangan reproduksi dasar (R0), dan menyelidiki keberadaan bifurkasi dari model yang dibangun. Bifurkasi maju, mundur dan maju dengan hysteresis muncul dari model yang telah terbentuk. Hasil analitik didukung oleh simulasi numerik terkait elastisitas dan sensitivitas R0 serta simulasi autonomous.

 

---

Atherosclerosis is a narrowing of the arteries due to the buildup of plaque on the artery walls resulting from an unhealthy lifestyle. According to the social science approach, the wrong lifestyle can be ”infection” to other people. The form of treatment for atherosclerosis patients is through bypass surgery, which must be performed by specialists and in specific hospitals, both of which have a limited number. If the number of patients with atherosclerosis complications continues to increase, it will result in no longer optimal treatment. This study aims to build a model of atherosclerosis spread without and taking into account the effect of limited hospital resources, known as the saturation effect. Both models were formed by dividing the human compartment into populations susceptible, infected with atherosclerosis, and people with atherosclerosis who are undergoing treatment. The models that have built are then analyzed analytically and numerically. Analytical studies carried out to find and analyze the equilibrium point, determine the basic reproduction number (R0), and investigate the existence of a bifurcation of the built model. Forward bifurcation, backward bifurcation, and forward bifurcation with hysteresis appear from the model that has formed. The analytical results supported by numerical simulations related to elasticity and sensitivity of R0 as well as autonomous simulations.

 

"

"Penlitian ini membahas tentang eliminasi componen metallic dan saturasi componen olefin bersama dengan eliminasi componen lain yang juga tidak di inginkan yang akan mempengaruhi laju reaksi dan kualitas produk. Solusi dari masalah ini adalah dengan mendesain sebuah trickle bed reactor berisikan Cobalt Molybdenum sebagai katalis yang dilengkapi dengan pelindung alumina dan mengandung HCL anhidrat. Reaktor ini mempunyai tinggi 3.33 m dan lebar diameter 1.5 berisikan 3080 kg katalis. Reactor yang mempunyai volume 5.874 m3 ini di desain untuk memproses 1 kg/s naphtha yang mengandung 0.03wt% sulfur, 40 ppb lead, dan 2vol% olefin.

---

This research discusses on removal of metallic compound and saturation of olefin with addition to other impurities removal from selected naphtha composition since it affects overall reaction rate and product quality. The solution is to design a trickle bed reactor loaded with Cobalt Molybdenum catalyst supported with alumina guard and potentially impregnated with anhydrous HCL. The reactor dimension is found to be 3.33 m in height and 1.5 in diameter packed with 3080 kg of catalyst. This 5.874 m3 reactor is designed to treat 1 kg/s naphtha which contains 0.03wt% sulphur, 40 ppb of lead and 2vol% of olefin."

"This book about olefin metathesis of renewable platform chemicals, Pd-catalysed telomerisation of 1,3-dienes with multifunctional renewable substrates - versatile routes for the valorisation of biomass-derived platform molecules, hydroformylation and related reactions of renewable resources, catalytic oxidation and deoxygenation of renewables with rhenium complexes, and recent developments in catalytic activation of renewable resources for polymer synthesis."

"This book about Pd-catalyzed coupling reactions, applications of rhodium-catalyzed hydroformylation in the pharmaceutical, agrochemical and fragrance industries, ruthenium-catalyzed selective hydrogenation for flavor and fragrance applications, asymmetric hydrogenation, case study : sequential Pd-catalyzed cross-coupling reactions : challenges on scale-up, pilot plant scale synthesis of an aryl-indole - scale up of a suzuki coupling, development of a mild and robust method for palladium catalysed cyanation on large scale, and application of ring closing metathesis strategy to the synthesis of vaniprevir (MK-7009), a 20-membered macrocyclic HCV protease inhibitor."

"This book about selectivity in palladium catalyzed allylic substitution, computational insights into palladium-mediated allylic substitution reactions, palladium-catalyzed enantioselective allylic substitution, iridium-catalyzed asymmetric allylic substitutions, molybdenum- and tungsten-catalyzed enantioselective allylic substitutions, copper-catalyzed enantioselective allylic substitution, allylic substitutions catalyzed by miscellaneous metals, and enantioselective allylic substitutions in natural product synthesis."