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Aditya Fergiawan
Perbandingan karakteristik dosimetri film gafchromic xr rv3 dan ebt2 untuk verifikasi dosimetri pada radioterapi = A comparative study of dosimetry characteristics between gafchromic xr rv3 and ebt2 film for dosimetry verification in radiotherapy
"Penelitian ini bertujuan untuk mempelajari karakteristik dosimetri dari film gafchromic XR-RV3 yang memiliki sensitifitas terhadap rentang dosis 1 cGy hingga 30 Gy serta membandingkannya dengan film EBT2 dengan rentang dosis 1 cGy hingga 40 Gy untuk verifikasi dosis pada Radioterapi. Karakteristik film seperti respon terhadap dosis tinggi, pengaruh energi serta orientasi film menjadi fokus penelitian. Pengukuran dilakukan menggunakan energi Megavoltage x-rays (6 MV dan 10 MV), dan Cobalt 60 yang sudah dikalibrasi sesuai dengan protokol dosimetri IAEA TRS-398. Respon film pada masing-masing energi diukur pada rentang dosis 50 cGy hingga 10 Gy. Pemindaian pada masing-masing film menggunakan EPSON Perfection V700 flatbed scanner, mode transmisi untuk film EBT2 dan mode refleksi untuk film XR-RV3, 48 bit color, dan resolusi spasial 75 dpi. Data yang diperoleh dianalisa menggunakan software FilmQA Pro, ROI berukuran 3 x 3 cm2 pada bagian tengah dari film untuk memperoleh nilai pixel rata-rata. Untuk masing-masing nilai pixel yang diperoleh dari masing-masing film selanjutnya ditentukan nilai rata-rata net Optical Density (netOD). Respon bacaan film EBT2 dan XR-RV3 pada rentang energi yang berbeda menunjukkan pengaruh energi yang rendah dengan deviasi rata – rata sebesar ±1%. Hasil perbandingan karakteristik respon bacaan film EBT2 dan XR-RV3 untuk masing-masing modalitas energi berbeda menunjukkan deviasi sebesar ±3%. Pengujian respon bacaan film XR-RV3 pada sisi orientasi yang berbeda tidak menunjukkan perbedaan yang signifikan dengan deviasi rata – rata sebesar 0.2%. Hasil evaluasi profil berkas menggunakan film XR-RV3 menunjukkan jumlah noise (disturbance) yang lebih banyak dibandingkan dengan EBT2. Pengukuran nilai simetris dan kerataan berkas pada rentang energi Cobalt-60 menunjukkan penyimpangan yang cukup besar pada posisi film horizontal terhadap sumbu utama berkas yaitu diatas 30%. Pengujian sensitifitas respon bacaan film XR-RV3 pada dosis tinggi dan dosis rendah menunjukkan hasil yang lebih baik dibandingkan dengan film EBT2.
The purpose of this study is to compare the dosimetry characterization of XR-RV3 film with its sensitivity to dose levels from 1 cGy to 30 Gy and EBT2 film with its sensitivity to dose levels from 1 cGy to 40 Gy for dose verification in radiation therapy. The characteristics of film such as response at high dose levels, energy dependence and side orientation dependence to scanner were the main focus of this study. The film response to each energy (foton 6 MV, 10 MV and Cobalt-60) was measured over the dose levels from 50 cGy to 10 Gy and the output source were calibrated following IAEA TRS-398 Dosimetry Protocol. Each film piece was scanned using EPSON Perfection V700 flatbed scanner, 48-bit color, 75 dpi spatial resolution, Transmission mode for EBT2 film and Reflection mode for XR-RV3 film. The data were analyzed using FilmQA Pro Software and for each scanned image, a ROI size 3 x 3 cm2 at the field center was selected to obtain the mean pixel value. Furthermore, the pixel value from each film were calculated to find the average of net Optical Density (netOD). From this study, the result revealed that there was no significant difference in characteristics response between XR-RV3 and EBT2 film with standar deviation of ±3%. The energy dependence of XR-RV3 and EBT2 film was found to be relatively small within measurement uncertainties ±1%. The dependence of XR-RV3 film side orientation is negligibly small with the standard deviation of 0.2%. The result of beam profile dosimetry evaluation using XR-RV3 showed more amount of noise or disturbance than EBT2 film. The measurement of beam symmetry and beam flatness on energy range of Cobalt-60, showed a significant error of film in horizontal position at central axis beam that was above 30%. In addition, the sensitivity of response XR-RV3 film at high and low dose shown better result than EBT2 film."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S57939
UI - Skripsi Membership  Universitas Indonesia Library
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Pamungkas Hudigomo
Verifikasi dosis pada imrt dan vmat berbasis film gafchromic xr rv3 = Dose verification on imrt and vmat based on gafchromic film xr rv3
"Telah dilakukan penelitian yang bertujuan untuk mengimplementasikan film Gafchromic XR-RV3 untuk verifikasi dosis radioterapi pada IMRT dan VMAT. Evaluasi dosis pada target ditentukan dengan meletakkan film Gafchromic XRRV3 dan EBT2 padqa slab fantom Rando Alderson. Percobaan dilakukan dengan menggunakan Varian Clinac Trilogy, Inc. Proses simulasi terlebih dahulu dilakukan pada fantom Rando Alderson bagian thorax dan pelvis di CT simulator Phillips, Inc. Dua kasus perencanaan IMRT dan VMAT dibuat menggunakan TPS Eclipse ver. 10. Film Gafchromic yang telah dipapar kemudian dipindai menggunakan scanner Epson Perfection V700 ke dalam format tagged image file (.TIFF) dengan 72 dpi dan RGB 48 bit yang kemudian dianalisis menggunakan algoritma in-house yang telah dikembangkan oleh penelitian sebelumnya. Dalam penelitian ini dilakukan perbandingan pengukuran distribusi dosis pada film Gafchromic XR-RV3 dan EBT2 untuk mendapatkan dosis rata-rata dalam bentuk kurva histogram. Hasil penelitian ini memiliki persentase kesalahan terhadap dosis preskripsi pada kasus kanker prostat sebesar -4.85% pada film Gafchromic EBT2 dan -1.94% pada film Gafchromic XR-RV3 dengan teknik penyinaran IMRT, sedangkan untuk teknik penyinaran VMAT sebesar -4.48% pada film Gafchromic EBT2 dan -7.47% pada film Gafchromic XR-RV3. Di sisi lain, persentase kesalahan terhadap dosis preskripsi pada kasus kanker paru-paru dengan teknik penyinaran IMRT adalah 14.47% pada film Gafchromic EBT2 dan -4.37% pada film Gafchromic XR-RV3, sedangkan untuk teknik penyinaran VMAT sebesar 51.64% pada film Gafchromic EBT2 dan -28.07% pada film Gafchromic XR-RV3.
The research aims to implement Gafchromic XR-RV3 films in order to verify the dose of radiotherapy on IMRT and VMAT. The evaluation of targeted dose is determined by putting films of Gafchromic XR-RV3 and EBT2 on Rando Alderson slab fantom. The experiment was performed with Varian Clinac Trilogy, Inc. The simulation process was initially conducted on thorax and pelvis on Phillips Inc.’s CT Simulator. Two cases of IMRT and VMAT plans were made using Eclipse TPS ver. 10. Exposed Gafchromic films then scanned using Epson Perfection V700 into (.TIF) format in 72 dpi and RGB 48 bit which was analyzed by in-house algorithm that had been developed on a previous research. The comparison between EBT2 and XR-RV3 Gafchromic films were used to obtain average dose in the form of histogram curve. The percentage of errors in the case of prostate cancer toward the planned dose were -4.85% in EBT2 Gafchromic films and -1.94% in the XR-RV3 Gafchromic films on IMRT technique, whereas for VMAT were -4.48% on EBT2 Gafchromic films and -7.47% on XR-RV3 Gafchromic films. On the other hand, the percentage of errors in the case of lung cancer toward the planned dose with IMRT technique were 14.47% on EBT2 Gafchromic films and -4.37% on XR-RV3 Gafchromic films, while for VMAT were 51.64% on EBT2 Gafchromic films and -28.07% on XR-RV3 Gafchromic films."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S57739
UI - Skripsi Membership  Universitas Indonesia Library
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Putri Diah Lestari
Karakteristik dosimetri radioterapi lapangan kecil pada film gafchromic EBT2 dengan variasi terhadap resolusi citra scanner = Dosimetry characterization for small field radiotherapy in gafchromic EBT2 film with variation of scanner image resolution
"Radioterapi lapangan kecil mulai banyak digunakan pada radioterapi modern seperti Intensity modulated radiotherapy (IMRT), stereotactic radiosurgery (SRS), dan Volumetric modulated arc therapy (VMAT). Akurasi terhadap pengukuran profil berkas dan percentage depth dose (PDD) menjadi kompleks karena ketidakseimbangan elektron. Oleh karena itu, film Gafchromic EBT2 digunakan untuk dosimeter radioterapi lapangan kecil karena memiliki resolusi spasial yang tinggi. Analisa dosimetri pada film Gafchromic EBT2 sangat dipengaruhi oleh penggunaan resolusi spasial citra. Penggunaan resolusi yang terlalu tinggi dapat menyebabkan noise yang cukup besar sebaliknya resolusi citra yang terlalu rendah tidak mampu menampilkan hasil analisa yang cukup akurat. Dengan demikian penggunaan resolusi citra yang optimum menjadi parameter penting dalam analisa dosimetri pada film Gafchromic EBT2. Resolusi citra yang optimum dapat ditentukan dengan melakukan uji respon terhadap variasi resolusi citra yakni : 50, 75, 100, 150, dan 240 dpi pada saat melakukan scanning film dengan Epson Perfection V700 menggunakan orientasi film landscape. Analisa dosimetri dilakukan menggunakan algoritma MATLAB dan dibandingkan dengan penelitian sebelumnya menggunakan ImageJ, Monte Carlo dan PPC untuk melihat karakteristik dosimetri terhadap penggunaan resolusi. Secara keseluruhan hasil evaluasi menunjukkan kondisi optimum resolusi citra 150 dpi diperoleh pada TPR20,10 dengan S.D. 8.10 % dan dmax dengan S.D 4.78%. Hasil evaluasi profil berkas menunjukkan resolusi optimum untuk FWHM dan Penumbra dicapai pada resolusi 75 dpi dengan S.D. 7.0 2% dan 12.43%. Hasil evaluasi VACF menunjukkan resolusi optimum dicapai pada resolusi 50 dan 75 dpi. Hasil yang diperoleh dari masing-masing parameter dosimetri memiliki kecenderungan optimum pada resolusi citra75 dpi.
Small field radiotherapy were increasing used in modern radiotherapy especially in intensity modulated radiotherapy (IMRT), stereotactic radiosurgery (SRS), and volumetric modulated arc therapy (VMAT). Accurate beam profile and percentage depth dose (PDD) measurements of such as beams were complicated due to the electron disequilibrium. Hence the EBT2 (external beam therapy) Gafchromic film was used for dosimetry small field radiotherapy because of its high spatial resolution. Spatial resolution influence dosimetric analyze for EBT2. More perturbation cause by using high spatial resolution otherwise low image spatial resolution couldn?t determined accurately. Such as, small field radiotherapy required the optimum image resolution for important parameter in dosimetric analyze EBT2. Optimum image resolution could be determine with testing dosimetric characterization to resolution response by 50, 75, 100, 150, and 240 dpi with landscape film orientation during film scanning by Epson Perfection V700. Dosimetric analyze was done by MATLAB algorithm and compare to ImageJ, Monte Carlo and PPC from prior research to evaluate dosimetry characteristic to image resolution. The results show that optimum image resolution was 150 dpi with S.D. 8.10 % and 4.78% for TPR20,10 and dmax respectively. Beam profile evaluation for FWHM dan Penumbra attained for 75 dpi with S.D. 7.0 2% and 12.43%. VACF evaluation show that optimum image resolution rich at 50 and 75 dpi. The result for each dosimetry parameter attained to optimum image resolution at 75 dpi"
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S54792
UI - Skripsi Membership  Universitas Indonesia Library
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Mukhlisin
Verifikasi dosimetri efek gerak target tumor paru pada teknik IMRT dan VMAT menggunakan fantom toraks dinamik in-house dengan detektor TLD-100 LiF:Mg, Ti ROD dan film gafchromic EBT2 = Dosimetry verification of lung tumor motion effect on IMRT and VMAT treatment using in house dynamic thorax phantom with TLD100 LiF: Mg,Ti ROD and gafchromic EBT2 film detectors
"Gerak tumor akibat pernapasan pasien merupakan masalah yang signifikan dalam pengobatan radioterapi kanker paru-paru, khususnya teknik radioterapi modern Intensity Modulated Radiotherapy (IMRT) dan Volumetric Modulated Arc Therapy (VMAT). Interaksi gerakan antara gerak target tumor dan MLC (interplay effect) memiliki keterbatasan dalam hal modulasi intensitas radiasi, probabilitasnya hanya sebagian kecil Planning Target Volume (PTV) menerima dosis radiasi sesuai perencanaan dosis Treatment Planning System (TPS) pada waktu tertentu.
Penelitian ini melakukan verifikasi dosimetri antara dosis yang direncanakan TPS dan dosis yang diterima volume tumor, akibat adanya interplay effect pada teknik IMRT dan VMAT. Penelitian menggunakan fantom toraks dinamik in-house dengan target tumor bergerak translasi arah superior-inferior dengan variasi amplitudo dan periode gerak tumor sebesar 9,3 mm dan 2,3 sekon, 20 mm dan 3,44 sekon, 30 mm dan 4,22 sekon. Pengukuran dosis titik dengan meletakkan dosimeter TLD-100 LiF:Mg,Ti dan Film Gafchromic EBT2 pada titik tengah target tumor dan organ at risk spinal cord. Penyinaran teknik IMRT menggunakan 7-field dan teknik VMAT menggunakan Rapidarc partial double arc dengan dosis preskripsi (95%) sebesar 200 cGy per fraksi.
Hasil penelitian menunjukkan bahwa kehadiran gerak target tumor paru-paru menyebabkan efek dosimetri yang tidak diinginkan berupa underdosage dalam volume tumor. Deviasi dosis rata-rata pada target tumor antara perencanaan dosis TPS dan hasil pengukuran pada teknik IMRT dengan target tumor bergerak statis, bergerak 9,3 mm, bergerak 20 mm, bergerak 30 mm berturut-turut sebesar 0,3% sampai 0,5%, -2,7% sampai -3,0%, -3,7% sampai -4,6%, dan -6,0% sampai -6,6%, sedangkan deviasi dosis pada teknik VMAT berturut-turut sebesar 0,2% sampai 0,9%, -1,6% sampai -1,9%, -2,9% sampai -3,1%, dan -5,0% sampai -5,3%. Hal berbeda, deviasi dosis untuk organ at risk spinal cord pada teknik IMRT berturutturut sebesar -5,6% sampai -1,0%, -6,8% sampai -6,9%, -3,7% sampai -5,9%, dan 0,7% sampai 1,0%, sedangkan deviasi dosis pada teknik VMAT berturut-turut sebesar -1,4% sampai -3,1%, -3,0% sampai -6,3%, -1,6% sampai -4,2%, dan 0,1% sampai 0,9%. Kenaikan amplitudo gerak target tumor menyebabkan dosis yang diterima volume tumor menurun. Namun sebaliknya, adanya kenaikan amplitudo gerak target tumor menyebabkan dosis yang diterima organ at risk spinal cord meningkat.
Tumor motion due to patient's respiratory is a significant problem in radiotherapy treatment of lung cancer, especially in modern radiotherapy treatment of Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT). The interplay effect is the effect that may occur as the motion of Linac (primarily the MLC) and motion of the tumor target interferes. At delivery dose treatment, a small part of Planning Target Volume (PTV) does not recover dose according to Treatment Planning System (TPS) Prescription.
This investigation was carried out through dosimetry verification between TPS and actual dose by tumor volume due to the interplay effect in IMRT and VMAT treatment. Tumor target of in-house dynamic thorax phantom was designed in linier sinusoidal motion toward superior-inferior direction with amplitude and period variation of tumor motion of 9,3 mm and 2,3s, 20 mm and 3,44s, 30 mm and 4,22s respectively. For point dose measurement, TLD-100 LiF:Mg,Ti and gafchromic EBT2 film detectors were took placed at midpoint of tumor target and spinal cord. IMRT treatment irradiation was applied by 7-fields and VMAT treatment by partial double arc, with prescription dose (95%) of 200 cGy per fraction.
The results showed that the occurrence of lung tumor target motion causes underdosage dosimetry effect in tumor volume. Mean dose deviation of tumor target between TPS and measurement in IMRT treatment by tumor target moves at condition of static, 9,3 mm, 20 mm and 30 mm were 0,3% to 0,5%, -2,7% to -3,0%, -3,7% to -4,6%, and -6,0% to -6,6% respectively while dose deviation in VMAT treatment were 0,2% to 0,9%, -1,6% to -1,9%, -2,9% to -3,1%, and -5,0% to -5,3% respectively. On the other hand, mean dose deviation of spinal cord in IMRT treatment were -5,6% to -1,0%, -6,8% to -6,9%, -3,7% to -5,9%, and 0,7% to 1,0% respectively and in VMAT treatment were -1,4% to -3,1%, -3,0% to -6,3%, -1,6% to -4,2%, and 0,1% to 0,9% respectively. The increment amplitude of tumor target motion reduced dose received by tumor volume and conversely, increased dose received by spinal cord."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2015
T43728
UI - Tesis Membership  Universitas Indonesia Library
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Adi Teguh Purnomo
Komparasi dosimetri in vivo teknik vmat pada fantom rando alderson dengan detektor tld, film gafchromic ebt2 dan dioda semikonduktor = Comparison of in vivo dosimetry in vmat technique for rando alderson phantom using tld, gafchromic ebt2 and diode semiconductor
"Evaluasi dosis radiasi yang diterima pasien dapat dilakukan menggunakan metode dosimetri in-vivo dengan melakukan pengukuran dosis masukan yang didefinisikan sebagai dosis serap pada kedalaman maksimum. Dosimeter in-vivo yang digunakan adalah TLD-100 rod, Film Gafchromic EBT2, dan dioda EDP-153G yang dikalibrasi berdasarkan protokol IAEA dan ESTRO. Hasil faktor kalibrasidetektor dioda sebesar 0.0988 cGy/ADU dan 0.0966 cGy/ADU untuk protokol IAEA dan ESTRO sedangkan Faktor kalibrasidetektor TLD memiliki rata-rata perbedaan sebesar 3.69 ± 0.04 %. Selain itu, faktor koreksi dioda EDP-153G terhadap variasi SSD, luas lapangan, dan linieritas dosis berada dalam rentang nilai 0.99-1.01 untuk protokol IAEA dan ESTRO sedangkan faktor koreksi terhadap sudut sinar datang berada dalam rentang nilai 1.028 - 1.037 dan 1.027-1.057 untuk protokol IAEA dan ESTRO. Pengukuran dosimetri in-vivo dititikberatkan pada kasus kanker paru dan prostat dengan meletakkan dosimeter in-vivo diatas permukaan kulit untuk beberapa titik pengukuran. Dosis masukan yang diperoleh bervariasi untuk setiap titik pengukuran akibat adanya perbedaan fluence. Evaluasi dosis pada organ target juga ditentukan dengan meletakkan film Gafchromic EBT2 pada slab fantom Rando Alderson. Persentase error yang diperoleh terhadap dosis yang direncanakan yakni sebesar 0.03% pada film 1 dan 2.5% pada film 2 untuk kanker paru sedangkan untuk kanker prostat sebesar 5.88% untuk film 1 dan 5.50% untuk film 2.
Evaluation of the radiation dose received by the patient could be performed with the in-vivo dosimetry by mean of the entrance dose measurement which defined as the absorbed dose to the maximum depth. TLD-100 rod, Gafchromic EBT2 film, and diode EDP-153G were used as in-vivo dosimeters and calibrated by the IAEA and ESTRO protocol. The results of calibration factor for diode EDP-153G was 0.0988 cGy/ADU and 0.0966 cGy/ADU for the IAEA and ESTRO, respectively while the differences of mean percentage was 3.69 ± 0.04 % relative to IAEA protocol for TLD. In addition, a correction factor for diode EDP-15­3Gto the variation of SSD, field size, and dose linearity were within the range of0.99-1.01 for the IAEA and ESTRO while the angular correction factor was at 1.028-1.037 and 1.027-1.057 for the IAEA and ESTRO protocol, respectively. The in-vivo dosimetry measurement was concerned in lung and prostate carcinoma by putting the in-vivo dosimeters on skin surface at some points of interest. The entrance dose measurement was varied for each point of measurement due to difference of fluence. The target dose evaluation was also determined by placing the Gafchromic EBT2 Film into slab of Rando Alderson phantom. The percentage error to the planned dose was 0.03% at the film 1 and 2.5%at the film 2 for lung carcinoma while for prostate carcinoma was 5.88% for the film 1 and 5.50% for film 2. "
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S54915
UI - Skripsi Membership  Universitas Indonesia Library
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Reza Aditya
Studi distribusi dosis pasien kardiologi intervensional dengan menggunakan film gafchromic XR- RV3 dan TLD 100 rod pada fantom rando = Study of interventional cardiology patient dose distribution using gafchromic XR RV3 film and TLD 100 rod in fantom rando
"Pada prosedur kardiologi intervensional pasien akan menerima radiasi primer berintensitas tinggi dari berkas utama sinar-X, sehingga dosis yang didapatkan cukup besar. Dengan demikian, perlu adanya studi distribusi dosis untuk melihat bagaimana penyebaran dosis pada organ-organ tubuh, dengan menggunakam film Gachromic XR-RV3 dan TLD 100 jenis rod yang telah diletakkan di dalam fantom Rando berbentuk manusia (wanita dewasa) sebagai pengganti pasien dengan parameter eksposi : kV rata-rata = 90 kV, laju frame = 15 fps, kuat arus = 6,2 mA dengan ukuran FPD = 15 cm x 15 cm. Distribusi laju dosis terbesar berada pada radius 0 cm sampai dengan 5 cm dari pusat lapangan, kemudian turun drastis pada radius 7,5 cm dan sudah tidak terdeteksi nilai laju dosis radius 10 cm. Untuk nilai laju dosis terbesar terdapat pada bagian pusat lapangan yaitu sebesar 6,345 ±0,097 mGy/min. Pada pengukuran laju dosis di beberapa Organ at Risk (OAR) dengan menggunakan Film Gafchromic XR-RV3 dan TLD 100 rod sebagai dosimeter didapatkan laju dosis pada Film Gachromic XR-RV3 dan TLD 100 rod dengan nilai terbesar terdapat pada organ jantung bagian tengah berturut-turut yaitu 2,742±0.029 mGy/min dan 2,791±0.161 mGy/min. Perbedaan nilai laju dosis antara Film Gachromic XR-RV3 dengan TLD 100 rod berkisar antara 0,53 % sampai dengan 13,80%.
In interventional cardiology procedures patients will receive primary radiation of high intensity X-rays beam, so that dose received by the patient is relatively high. Thus, the dose distribution studies needed to see how the spread of the dose to the organs of the body, using Gachromic XR - RV3 film and TLD 100 type rod that has been placed in phantom Rando (adult women) as a replacement for a patient with parameters: average kV = 90 kV, frame rate = 15 fps, electric currents = 6.2 mA with FPD size = 15 cm x 15 cm. The distribution of the largest dose rate is at a radius of 0 cm to 5 cm from the center of the field, then dropped away at a radius of 7.5 cm and had no detectable dose rate value at radius of 10 cm. For the largest dose rate values are at the center of the field is about 6.345 ± 0.097 mGy / min. In the measurement of the dose rate in some organs at risk ( OAR ) using Gafchromic XR - RV3 film and TLD 100 rod obtained dose rate at Gachromic XR-RV3 film and TLD 100 rod with the largest value found in the central part of the heart organ ie 0.029 ± 2.742 mGy / min and 2.791 ± 0.161 mGy / min, respectively. The difference between the value of the dose rate Gachromic XR-RV3 film with TLD 100 rod ranged from 0.53% to 13.80%."
2013
S54336
UI - Skripsi Membership  Universitas Indonesia Library
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Henni Widyastuti
Pengaruh keberadaan film gafchromic xr rv3 terhadap kualitas citra pada prosedur kateterisasi jantung = Effect of gafchromic xr rv3 film existence to image quality in cardiac catheterization procedure
"[ABSTRAK
Dosimeter film Radiochromic XR-RV3 merupakan salah satu tipe dosimeter yang
dapat digunakan untuk mengukur dosis pasien pada prosedur kateterisasi jantung
dengan fluoroskopi sebagai pemandu. Namun, perlu dipastikan pengaruh
keberadaan film Radiochromic XR-RV3 terhadap kualitas citra. Penelitian ini
menggunakan fantom Kat Ped sebagai representasi jantung dewasa dan
membandingkan secara kuantitatif kualitas citra fantom yang dieksposi dengan
menggunakan film dan tanpa menggunakan film GafChromic XR-RV3. Kuantitasi
kualitas citra yang digunakan sebagai pembanding adalah Signal to noise ratio
(SNR) dan resolusi kontras tinggi. Signal to noise ratio (SNR) yang diperoleh
dianalisa menggunakan statistik t-test dengan confidence level 95%. Hasil analisa
menunjukkan tidak terdapat perbedaan SNR yang signifikan dengan menggunakan
film dan tanpa menggunakan film pada mode fluoroskopi low dose, normal dose
dan high dose dengan diskrepansi SNR <10%. Pada mode cine 15 fps low dan 15
fps normal, terdapat kenaikan SNR dengan menggunakan film dengan diskrepansi
<13% sedangkan pada mode cine 15 fps boost dan 25 fps coronary tidak terdapat
perbedaan signifikan SNR dengan diskrepansi rerata < 7%. Pada high contrast
analisa t-test untuk kedua mode fluoroscopy dan Cine tidak menunjukkan adanya
perbedaan signifikan dengan hasil non rejected pada confidence level 95%.
ABSTRACT
Radiochromic XR-RV3 film dosimeter is a type of dosimeter that can be used to
measure patient dose on cardiac catheterization procedure with fluoroscopy as a
guide. However, it is necessary to ensure the effect of Radiochromic XR-RV3 film
to image quality. This study used a Kat Ped phantom as a representation of the
adult heart and quantitatively compare the image quality by using a phantom that
exposed with film and without using film GafChromic XR-RV3. Quantitation of
image quality used for comparison is the signal to noise ratio (SNR) and high
contrast resolution. Signal to noise ratio (SNR) obtained statistically analyzed
using t-test with 95% confidence level. The analysis results showed no significant
difference in SNR using film and without using film on a low dose mode, the
normal dose, and high dose flouroscopy with SNR discrepancy <10%. In the cine
mode of 15 fps low and 15 fps normal, there is an increased SNR by using film
with discrepancy <13%, while in the cine mode of 15 fps boost and 25 fps
coronary there are no significant differences with mean SNR discrepancy <7%. At
high contrast t-test analysis for both Fluoroscopy and Cine mode, result showed no
significant difference with the results of non-rejected at the 95 % confidence level., Radiochromic XR-RV3 film dosimeter is a type of dosimeter that can be used to
measure patient dose on cardiac catheterization procedure with fluoroscopy as a
guide. However, it is necessary to ensure the effect of Radiochromic XR-RV3 film
to image quality. This study used a Kat Ped phantom as a representation of the
adult heart and quantitatively compare the image quality by using a phantom that
exposed with film and without using film GafChromic XR-RV3. Quantitation of
image quality used for comparison is the signal to noise ratio (SNR) and high
contrast resolution. Signal to noise ratio (SNR) obtained statistically analyzed
using t-test with 95% confidence level. The analysis results showed no significant
difference in SNR using film and without using film on a low dose mode, the
normal dose, and high dose flouroscopy with SNR discrepancy <10%. In the cine
mode of 15 fps low and 15 fps normal, there is an increased SNR by using film
with discrepancy <13%, while in the cine mode of 15 fps boost and 25 fps
coronary there are no significant differences with mean SNR discrepancy <7%. At
high contrast t-test analysis for both Fluoroscopy and Cine mode, result showed no
significant difference with the results of non-rejected at the 95 % confidence level.]"
Universitas Indonesia, 2015
S62229
UI - Skripsi Membership  Universitas Indonesia Library
cover
Ari Surya Miharja
Perbandingan karakteristik scanner vidar dosimetrypro advantage dan epson perfection v700 berbasis dosimetri film radiochromic ebt2 = Characteristics comparison of vidar dosimetrypro advantage and epson perfection v700 scanner based on radiochromic ebt2 film dosimetry
"Telah dilakukan penelitian untuk menentukan karakteristik dasar dari scanner yang digunakan untuk dosimetri film radiochromic EBT2. Dalam penelitian ini digunakan scanner Vidar DosimetryPro Advantage dan Epson Perfection V700. Pengujian yang dilakukan meliputi uji konsistensi scanner, uji variasi film to film, uji uniformitas scanner, uji efek orientasi film, uji suhu ruang penyimpanan film, uji fading film dan uji noise film/scanner. Scanner diuji menggunakan film EBT2 yang telah dipapar radiasi menggunakan Linac dengan modalitas foton 6 MV. Film mempunyai 8 buah lapangan berukuran 3 cm x 3 cm dengan dosis dari 31,31 - 250,48 cGy. Software yang digunakan untuk menganalisa hasil bacaan scanner adalah ImageJ dan FilmQA Pro. Dari hasil pengujian didapatkan konsistensi Vidar mode Logarithmic lebih baik dengan standar deviasi (SD) kurang dari 0,06%, sedangkan standar deviasi Epson mencapai 0,40%. Uniformitas Vidar juga lebih baik dengan SD kurang dari 0,76% dibandingkan Epson yang mencapai 1,16%. Orientasi film cukup berpengaruh terhadap hasil bacaan, terutama pada Epson, sehingga orientasi film harus konstan selama pemindaian. Pengujian noise film/scanner menunjukkan bahwa Epson menghasilkan noise yang lebih kecil sebesar 0,10% dibandingkan Vidar yang menghasilkan 0,33%. Performa Vidar secara keseluruhan lebih bagus daripada Epson terutama saat red channel saja yang dianalisa.
Has been done measurement of basic characteristic of Vidar DosimetryPro Advantage and Epson Perfection V700 scanner based on radiochromic EBT2 film dosimetry. The tests were consist of the consistency test, film to film variation test, scanner uniformity test, effect of film orientation test, room storage temperature test, film fading test and scanner noise test. The scanners performance were tested using The scanners performance were tested using EBT2 with eight separated 3 x 3 cm2 fileds to doses ranging from 31.31 - 250.48 cGy which was irradiated using photon beam of Linac 6 MV. For evaluation, ImageJ and FilmQA Pro were used. The performance of Vidar scanner is higher in consistency and unifromity with standard deviation of measurement 0.06% and 0.76% compare with with Epson scanner with standard deviation of 0,40% and 1.16%. The film orientation effect made a big different result especially in Epson that reached 10.65% differences between portrait and landscape orientation. The scanner noise was small: 0.10% in Epson and 0.33% in Vidar. The overall measurements of Vidar was better than Epson, especially because only red channel that was analyzed."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2014
S56087
UI - Skripsi Membership  Universitas Indonesia Library
cover
Retno Zurma
Koreksi lateral response artifacts (LRA) flatbed scanner pada film gafchromic dosimetri radioterapi teknik IMRT dan VMAT = Correcting lateral response artifacts (LRA of flatbed scanner towards gafchromic dosimetry film by conducting radiotherapy technics IMRT and VMAT
"[ABSTRAK
Film gafchromic EBT2 dan EBT3 cocok digunakan untuk jaminan kualitas (QA) pada treatment planning systems (TPS) dan linear accelerator (LINAC) serta verifikasi radioterapi teknik IMRT dan VMAT. Namun generasi selanjutnya dari film gafchromic EBT yaitu EBT2 dan EBT3 ketika dilakukan scanning (pemindaian) menggunakan scanner flatbed masih terdapat artefak geometris yang dahulunya juga ditemukan pada film EBT sehingga memerlukan penanggulangan dan koreksi yang sesuai. Pada penelitian ini menggunakan scanner flatbed Epson expression 10000XL, Epson perfection V700 dan Mikrotek 1000XL plus yang dapat menangkap warna dengan rinci dan presisi. Perangkat lunak yang digunakan dalam koreksi ini adalah FilmQA Pro 2015. Hasil yang diperoleh yaitu Koefisien A dan B diterapkan untuk variasi posisi lateral terhadap nilai tanggapan di lokasi yang bersamaan, sehingga pengkoreksian tanggapan artifak lateral dapat dilakukan. Pada dosis maksimum nilai koreksinya <0,5% dan pada kasus <0.2%. Pada pengukuran ulang untuk setiap film, standar deviasi yang diperoleh untuk setiap film sekitar 0.19%. Pengujian dosimetri channel tunggal (merah) sebelum dan sesudah koreksi pada kasus IMRT didapatkan hampir 91% dari piksel memenuhi 3% / 3mm kriteria gamma keseluruhan dengan ambang batas dosis > 10%. Untuk pengujian kasus VMAT, film di scan dengan posisi di pusat scanner dan posisi ektrim tepi scanner, maka pengukuran di channel warna merah 4% lebih tinggi dibandingkan channel warna hijau dan biru. Rata-rata konsistensi pengukuran dosis selama daerah terkena dosis > 100 cGy adalah sekitar 21,8 cGy dan di daerah yang paling dekat dengan tepi scan window sekitar 10 mm dengan perbedaan dosis 35 cGy. Setelah dilakukan koreksi, rata-rata konsistensi dosis pada tiga channel di sekitar daerah terpapar sekitar 5,1 cGy. Perbedaan dosis antar channel sekitar 9 cGy. Hasil ini menunjukkan koreksi respon artefak lateral memang perlu dilakukan. Respon yang diukur tergantung pada posisi film pada pemindai dan dosis yang diberikan. Pengukuran pada channel warna merah menunjukkan sensitivitas yang lebih besar pada dosis rendah, sedangkan respon pada channel hijau atau biru memberikan perpanjangan jangkauan dinamis dari film ke dosis tinggi. Metode triple-channel dosimetri telah terbukti memiliki keuntungan signifikan atas single channel dosimetry dengan akurasi dosimetri yang baik.
ABSTRACT
The film of gafchromic EBT2 and EBT3 are appropriate for quality assurance (QA) to the radiotherapy technics verification of IMRT and VMAT. In the next generations of EBT which are EBT2 and EBT3, are still attained the geometrical artifacts once scanning by flatbed scanner which is used to be found on EBT film in order to need an overcome ways and an appropriate correction. This research used a flatbed scanner EPSON expression 10000XL, EPSON perfection V700 and Microtech 1000XL plus and FilmQA Pro 2015 as a software for correcting it. The result shows that coefficient A and B were applied for lateral correction artifacts responses can be made. On the maximum dose, it has correction value as much as <0,5% and in case was <0.2%. The deviation standard was approximately 0,19% on re-measure for each film. Prior to the dosimetry measurement of single channel (red) and subsequent to the correction IMRT has got almost 91% of pixel which met with gamma criteria, 3% / 3mm, with dose threshold 10% TH. In the measurement of VMAT‟s case, film scanned on the center of scanner and the extreme position of the scanner edge. Thus, measurement in the red channel was 4% higher than green and blue channel. The average of dose measurement consistency during area exposed to doses > 100 cGy is approximately 21,8 cGy and the closest area with the edge of scan window is around 10 mm at difference doses 35 cGy. After correction, the average of doses consistency was 5,1 cGy on the three channel where exposed. The distinction of doses was approximately 9 cGy among channels. This result stated that the correction of artifacts lateral response is needed to carry on. The method of triple-channel dosimetry has the significant advantage on single-channel dosimetry with a good consistency. Through escalation dose and variation of lateral position, the distinct response would be increased on single-channel which is red channel. The measurement on red channel reveals the highest sensitivity on the slight dose. Whereas, a green or blue channel response provides a dynamic range extension of film to a high dose. Thus, the method of dosimetry triple-channel has the significant contribution of single-channel evidently with a good dosimetric accuracy., The film of gafchromic EBT2 and EBT3 are appropriate for quality assurance (QA) to the radiotherapy technics verification of IMRT and VMAT. In the next generations of EBT which are EBT2 and EBT3, are still attained the geometrical artifacts once scanning by flatbed scanner which is used to be found on EBT film in order to need an overcome ways and an appropriate correction. This research used a flatbed scanner EPSON expression 10000XL, EPSON perfection V700 and Microtech 1000XL plus and FilmQA Pro 2015 as a software for correcting it. The result shows that coefficient A and B were applied for lateral correction artifacts responses can be made. On the maximum dose, it has correction value as much as <0,5% and in case was <0.2%. The deviation standard was approximately 0,19% on re-measure for each film. Prior to the dosimetry measurement of single channel (red) and subsequent to the correction IMRT has got almost 91% of pixel which met with gamma criteria, 3% / 3mm, with dose threshold 10% TH. In the measurement of VMAT‟s case, film scanned on the center of scanner and the extreme position of the scanner edge. Thus, measurement in the red channel was 4% higher than green and blue channel. The average of dose measurement consistency during area exposed to doses > 100 cGy is approximately 21,8 cGy and the closest area with the edge of scan window is around 10 mm at difference doses 35 cGy. After correction, the average of doses consistency was 5,1 cGy on the three channel where exposed. The distinction of doses was approximately 9 cGy among channels. This result stated that the correction of artifacts lateral response is needed to carry on. The method of triple-channel dosimetry has the significant advantage on single-channel dosimetry with a good consistency. Through escalation dose and variation of lateral position, the distinct response would be increased on single-channel which is red channel. The measurement on red channel reveals the highest sensitivity on the slight dose. Whereas, a green or blue channel response provides a dynamic range extension of film to a high dose. Thus, the method of dosimetry triple-channel has the significant contribution of single-channel evidently with a good dosimetric accuracy.]"
2016
T45204
UI - Tesis Membership  Universitas Indonesia Library
cover
Khaerunnisa
Evaluasi perbandingan dosimetri film menggunakan metode scanner, densitometer, dan spektrofotometer dan aplikasinya dalam radioterapi = Comparative evaluation of film dosimetry using acanner, densitometer, and Spectrophotometer Methods and Its Application in Radiotherapy
"ABSTRAK
Film EBT3 merupakan model film radiochromic yang didisain khusus untuk keperluan radioterapi eksternal (external beam therapy, EBT) respon film terhadap radiasi pengion mengakibatkan perubahan pada spektrum serapan dan sifat optiknya membuat film radiochromic menjadi pilihan yang banyak digunakan dalam bidang oncologi. Respon
film terhadap radiasi biasanya diukur dalam hal perubahan kerapatan optik (netOD) yang nilainya bergantung dari banyaknya berkas yang melewati film dan juga panjang gelombang cahaya dari alat pembaca (densitometer optik). Penelitian ini bertujuan menyelidiki pengaruh penggunaan densitometer optik yang berbeda, yakni scanner, densitometer dan spektrofotometer dalam mengukur respon dosimeter film terhadap radiasi pengion. Penyelidikan respon film dilakukan dengan mengirradiasi film menggunakan pesawat Linac Varian Trilogy dengan energi 6 MV. netOD yang terbaca pada film dilakukan dengan mengekstrak mean pixel value dari kanal merah ketika menggunakan scanner. Ketika menggunakan densitometer netOD dihasilkan dari
perubahan nilai OD yang terbaca secara langsung. Sedangkan nilai netOD didapat dengan melihat perubahan spektrum serapan film sesudah dan sebelum irradiasi menggunakan spektrofotometer. Evaluasi penggunaan metode dosimetri dilakukan menggunakan
fantom homogen untuk evaluasi dosis uji dan juga untuk evaluasi pada variasi lapangan penyinaran, dan fantom non-homogen (rando) untuk implementasi metode pada perlakuan klinis radioterapi. Untuk mendapatkan hasil pengukuran yang optimum juga dilakukan penyelidikan karakteristik spektrum serapan pada variasi level dosis dan variasi waktu pengukuran pasca irradiasi. Hasil pengukuran respon film menunjukkan tidak terjadi perubahan pita serapan film terhadap perubahan level dosis ataupun terhadap perubahan waktu pasca irradiasi, yakni berada pada pusat pada panjang gelombang 635
nm untuk pita serapan maksimum, dan pita serapan ke-dua berpusat pada 583 nm. Penyelidikan sensitivitas ketiga metode menghasilkan tren kurva sensitivitas yang mirip namum memiliki besar yang berbeda dimana sensitivitas tertinggi didapat ketika menggunakan spektrofotometer. Sementara ketidakpastian (1σ) netOD untuk ketiga
metode menghasilkan nilai ketidakpastian yang cukup besar untuk dosis dibawah 100 cGy dan nilai ketidakpastian mulai membaik ketika level dosis meningkat. Pada aplikasi klinis ketiga metode dosimeteri dievaluasi dengan melihat besar diskrepansi yang dihasilkan pada adaerah target kepala, paru-paru dan prostat. Penggunaan scanner dan
spektrofotometer menghasilkan rata-rata diskrepansi dibawah 2% untuk semua target pengukuran, sedangkan densitometer menghasilkan rata-rata diskrepansi sampai 3%.
ABSTRACT
EBT3 film is a radiochromic film model specially designed for external radiotherapy (EBT). The response of the film to ionizing radiation results in changes in the absorption spectrum and its optical properties making radiochromic films a widely used choice in oncology. The response of the film to radiation is usually measured in terms of the change in optical density (netOD) whose value depends on the number of beams passing through the film and also the wavelength of light from the reader (optical densitometer). This study aims to investigate the effect of using different optical densitometers, namely scanners, densitometers and spectrophotometers in measuring the response of film dosimeters to ionizing radiation. The investigation of the film response was carried out by irradiating the film using a Linac Varian Trilogy with an energy of 6 MV. The netOD read on the film was done by extracting the mean pixel value from the red channel when using a scanner. When using a densitometer the netOD results from changes in OD values that are read directly. While the netOD value was obtained by measuring changes in the absorption spectrum of the film after and before irradiation using a spectrophotometer. Evaluate the use of the dosimetric methods was carried out using homogeneous phantom
for the evaluation of test doses and also for evaluation of variations in the radiation field, and non-homogeneous phantom (rando) for the implementation of the method in clinical radiotherapy treatment. To obtain the optimum measurement results, an investigation of the characteristics of the absorption spectrum was also carried out at variations in dose levels and variations in measurement time after irradiation. The results of the measurement of the response of the film showed that there was no change in the absorption band of the film due to changes in dose levels or to changes in time after; irradiation, which was at the center at a wavelength of 635 nm for the maximum
absorption band, and the second absorption band was centered at 583 nm. The sensitivityinvestigation of the three methods resulted in a trend of similar sensitivity curves but different magnitudes with the highest sensitivity obtained when using a spectrophotometer. Meanwhile, the uncertainty (1σ) netOD for the three methods resulted
in a fairly large uncertainty value for doses below 100 cGy and the uncertainty value began to decrease as the dose level increased. In clinical application, the three dosimetric methods were evaluated by measuring the resulting discrepancy in the target areas of the
head, lungs and prostate. The use of a scanner and a spectrophotometer resulted in an average discrepancy of below 2% for all measurement targets, while the use of a densitometer resulted in an average discrepancy of up to 3%."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2020
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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