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"This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more."

"Written for busy professionals at the forefront of new drug development, "Drug delivery" gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination, including overviews, timely examples, and extensive references, of a host of specific subjects."

"Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug discrimination : applications to medicinal chemistry and drug studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action. The book provides medicinal chemists with a fuller understanding of the nature and use of drug discrimination studies for evaluating the action of drugs while helping pharmacologists understand and better interact with medicinal chemists and drug designers when sharing pharmacologic data."

"ABSTRAKTesis ini membahas model Integrated Care Pathway (ICP) perawatan pasiendengan penyalahgunaan NAPZA putus zat opioid sebagai salah satu kasus.Penelitian ini adalah penelitian kualitatif dengan desain deskriptif. Hasilpenelitian menunjukkan koordinasi, komunikasi, kesinambungan dan kolaborasipelayanan pasien putus zat opioid belum berjalan optimal yang melibatkanberbagai unsur disiplin keilmuan pada pelayanan yang diberikan. Model ICPyang diusulkan agar dikembangkan kembali dengan melibatkan berbagai multidisiplin ilmu yang terlibat di dalam pelayanan pasien dengan penyalahgunaanNAPZA putus zat opioid di RSKO Jakarta melalui sebuah kegiatan FGD yangmelibatkan lebih banyak tenaga kesehatan yang terkait dengan layanan sehinggadapat menghasilkan ICP yang sesuai dengan kebutuhan.

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ABSTRACTThis thesis discusses the model of Integrated Care Pathway (ICP) treatment ofpatients with drug abuse of opioid withdrawal as one case. This study is aqualitative study with a descriptive design. The results show coordination,communication, and collaboration continuity of patient care opioid withdrawalhas not run optimally involving various elements of scientific disciplines on theservice provided. ICP models are proposed for re-developed with the involvementof a variety of multi-disciplines involved in the care of patients with drug abuse ofopioid withdrawal in RSKO Jakarta through an FGD activities that involve morehealth workers associated with the service so that it can produce the ICP inaccordance with the requirements ."

"Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include : proteomics, glycoprotein mapping, natural products dereplication, lead identification screening, open-access LC/MS, in vitro drug screening written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce."