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"This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules."

"This book that addresses the modern aspects of bone healing and repair. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones."

"Reading the novels of D.H. Lawrence for the first time in his life is for the student of English Literature usually a be_wildering experience. At least, with me it certainly was the case. In the beginning I was really puzzled when reading these novels; and I hardly could disentangle the knot of problems in them which struck me as being subtle and complex, and even often seemingly contradictory. At the same time this initial confusion and bewilderment was a challenge for me to try to understand this unusual and interest_ing writer. Gradually I became aware that one of Lawrence's main preoccupations in his novels was the pursuit of happiness through personal relationships. Also I became aware that Lawrence assumed to teach mankind new ways in the realm of human experience through personal relationships.In this I was rather astonished to find Mr. Mark Spilka's judgement in his book The Love Ethic of D.H. Lawrence, that As The Prophet of individual regeneration, Lawrence had achieved a good measure of success; his vision of love, friendship, and life-responsibility had broadened and deepened, through the major novels, and had reached its fullest scope with Lady Chatterley's Lover_"

"This volume presents a new contribution for the field of Tissue Engineering with a focus on the development of mathematical and computational methods that are relevant to understand human tissues, as well to model, design, and fabricate optimized and smart scaffolds."