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"Latar belakang: Kondiloma akuminatum (KA) merupakan infeksi menular seksual tersering. Meskipun dinyatakan 90% lesi KA terkait HPV risiko rendah, tipe 6 dan 11, namun belum ada publikasi yang memaparkan tentang tipe HPV pada berbagai bentuk klinis KA di Indonesia. Tujuan: Mengidentifikasi tipe HPV pada berbagai bentuk klinis KA. Metode: Dilakukan penelitian potong lintang di Poliklinik Kulit dan Kelamin Rumah Sakit dr. Cipto Mangunkusumo, Indonesia, pada bulan April-Juli 2013, melibatkan 25 lelaki dan 12 perempuan berusia 20-57 tahun. Didapatkan 40 sampel DNA berasal dari 40 lesi KA pada 37 subyek penelitian (SP) dengan berbagai bentuk klinis. Identifikasi tipe HPV dilakukan dengan menggunakan HPV express matrix® yang mampu mendeteksi 21 tipe HPV baik risiko rendah maupun tinggi. Pemeriksaan ini mampu mengidentifikasi infeksi HPV multipel pada spesimen. Hasil: Pada 37 SP didapatkan berbagai bentuk klinis, 3 (8%) di antaranya ditemukan bentuk klinis multipel, sehingga keseluruhan lesi KA berjumlah 40. Tipe HPV teridentifikasi pada 34 lesi (85%). Terdapat 4 gambaran klinis KA dan tipe HPV terkait: (1) bentuk klasik 26 dari 40 lesi (65%): temuan terbanyak adalah HPV tipe risiko rendah pada 18 sampel, yaitu tipe 6, 11, 43, sementara pada 7 sampel terdapat ko-infeksi dengan tipe risiko rendah, dan pada 1 sampel tipe HPV tidak teridentifikasi, (2) bentuk keratotik 2 lesi (5%): pada 1sampel hanya ditemukan HPV tipe risiko tinggi yaitu tipe 35 dan pada 1 sampel tipe HPV tidak teridentifikasi, (3) papul dengan permukaan halus 9 lesi (22,5%): HPV tipe risiko rendah teridentifikasi pada 4 sampel, yaitu tipe 6, 11, 42, 43, sementara pada 3 sampel terdapat ko-infeksi dengan HPV tipe risiko rendah, dan pada 2 sampel tipe HPV tidak teridentifikasi, dan (4) papul datar-plak 3 lesi (7,5%): pada 2 sampel hanya ditemukan HPV tipe risiko tinggi, yaitu tipe 52 dan pada 1 sampel tipe HPV tidak teridentifikasi. Tipe HPV 6 dan atau 11 teridentifikasi pada 28 sampel (70%). Tipe HPV risiko rendah yang teridentifikasi adalah 6, 11, 42, dan 43, sedangkan tipe risiko tinggi yang teridentifikasi adalah 16, 31, 35, 39, 45, 52, 56, 66, dan 68. Kesimpulan: Penelitian ini adalah penelitian pertama di Indonesia yang mengidentifikasi tipe HPV pada berbagai bentuk klinis KA. Tipe yang paling banyak ditemukan pada KA tipe klasik adalah HPV risiko rendah tipe 6 dan 11. Beberapa tipe HPV risiko tinggi juga ditemukan pada beberapa lesi KA.

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Background: Condyloma acuminatum (CA) is the most common sexually transmitted infection. Although, it is stated that low-risk HPV types 6 and 11 are associated with 90% of genital warts, but there is no publication in Indonesia about identification of HPV types in various CA clinical manifestations.

Purpose: To identify HPV type among various clinical pictures of anogenital warts.

Method: A cross-sectional study is conducted in Dermato-Venereology Clinic Dr. Cipto Mangunkusumo National Hospital, Jakarta. Twenty five men and 12 women (20-57year-old) from April to July 2013 were eligible in this study. Fourty DNA samples from 40 lesions of 37 subjects with various clinical pictures of CA were collected. The HPV typing was based on PCR and dot blot hybridization using the HPV express matrix® which detects 21 HPV types of high- and low-risk, able to identify multiple types from a single specimen.

Result: Multiple clinical manifestations were found on 3 of 37 subjects (8%). HPV types were identified among 34lesions (85%). Four clinical manifestations of CA and HPV typing were documented: (1) classic 26 of 40 lesions (65%): low-risk HPV types (6, 11, 43), predominated in 18 samples, while 7 samples were co-infected with the high risk types and another sample had unidentified HPV types. (2) keratotic 2 lesions (5%): 1 sample only harbour the high risk HPV type 52, while the other was unidentified. (3) smooth papule 9 lesions (22.5%): Low-risk HPV types (6, 11, 42, 43) were found in 4 samples, while 3 samples were co-infected with the high risk types, while 2 others were unidentified, and (4) flat top papule to plaque 3 lesion (7.5%): 2 samples were unidentified and the other was high risk HPV type 52. HPV 6 and 11 can be identified in 28 samples (70%). The low risk HPV type had been identified were 6, 11, 42, and 43, while the high risk type were 16, 31, 35, 39, 45, 52, 56, 66, and 68.

Conclusion: This is the first study in Indonesia which identified HPV types in various CA clinical manifestations. The HPV low risk types 6 and 11 were the most prevalent in classic CA. Several high risk HPV types were also found in some CA lesions."

"Latar belakang : nevus melanositik didapat (NM) adalah salah satu kelainan pigmentasi melanositik yang dapat menjadi prekursor potensial melanoma. Telah diketahui bahwa tipe kulit putih merupakan salah satu faktor risiko terjadinya melanoma. Pola dermoskopi NM pada populasi kulit putih memiliki gambaran dermoskopik yang berbeda pada setiap tipe kulit (tipe I ? IV) menurut klasifikasi Fitzpatrick. Belum pernah dilaporkan perbedaan gambaran dermoskopik pada tipe kulit orang Indonesia yang umumnya berkulit sawo matang dengan tipe kulit IV dan V. Dianggap penting untuk mengetahui karakteristik gambaran klinis dan dermoskopik NM pada tipe kulit orang Indonesia yang meliputi tipe kulit III, IV dan V. Metode : penelitian ini menggunakan rancangan potong lintang, pada 96 subyek penelitian (SP) dewasa (usia 18-60 tahun) di Poliklinik IKKK RSCM Jakarta terbagi merata untuk setiap tipe kulit III, IV dan V. Dilakukan pemeriksaan gambaran klinis dan dermoskopik NM pada tiap SP. Gambaran klinis yang dinilai adalah morfologi klinis dan warna lesi. Hasil : didapatkan gambaran klinis NM yang paling banyak adalah lesi datar (88,44%), berwarna cokelat gelap (51,43%), dengan median ukuran 2 mm. Pola dermoskopik yang paling banyak ditemukan pada seluruh lesi NM adalah retikular (33,40%). Terdapat proporsi dan kecenderungan yang semakin meningkat pada pola retikular dengan meningkatnya kegelapan tipe kulit orang Indonesia (tipe kulit IV terhadap tipe kulit III OR 1,4 (95% CI 0,5-4,0); tipe kulit V terhadap tipe kulit III OR 1,7 (95% CI 0,6-4,8)). Kesimpulan : Tidak terdapat perbedaan gambaran klinis NM pada tiap tipe kulit orang Indonesia. Terdapat perbedaan pola dermoskopik pada tipe retikular dengan proporsi yang makin meningkat sesuai dengan tipe kulit yang makin gelap.

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Background : Acquired melanocytic nevi (MN) is one of melanocytic pigmentation disorder, which can be a potential precursor of melanoma. Fair skin type has been known as one of the risk factor for melanoma. The dermoscopic pattern of MN in white population is different among the skin types (type I ? IV) according to Fitzpatrick?s classification. The difference in dermoscopic pattern of MN among the skin types of Indonesian people, which commonly dark brown with types IV and V, has not been reported. It is important to know the clinical characteristics and dermoscopic pattern of MN in Indonesian people skin types, which includes the skin types of III, IV and V.

Method : We performed a cross sectional study in 96 adult patients (18-60 years old), distributed equally for each skin type III, IV and V, at the Dermatovenereology outpatient clinic Dr Cipto Mangunkusumo hospital Jakarta. Each subject was examined for clinical and dermoscopic pattern. Clinical characteristic include clinical morfology and color.

Result : The study found that the most frequent clinical characteristics of MN were planar lesion (88.44 %), dark brown color (53.43%), with median size 2 mm. The most frequent dermoscopic pattern in all MN lesions was reticular (33.40 %). There was increasing proportion and odds within reticular pattern with the increase of skin?s darkness of Indonesian people (skin type IV to type III with OR 1.4 (95% CI 0.5-4.0); skin type V to type III with OR 1.7 (95% CI 0.6-4.8), respectively).

Conclusion : Clinical characteristics were not significantly different among the skin types of Indonesian people. There was difference on dermoscopic pattern within the reticular type, showing an increase of its proportion in accordance with the darker skin types."

"ABSTRAKLatar belakang: Malassezia sp. berperan penting dalam patogenesis dermatitis seboroik DS . Pada penelitian di negara lain didapatkan M.globosa dan M.restricta sebagai spesies predominan pada lesi kulit kepala DS. Belum diketahui pola sebaran Malassezia pada kulit kepala pasien DS di Indonesia dan hubungannya dengan derajat keparahan DS. Tujuan: Mengetahui distribusi spesies Malassezia pada kulit kepala pasien DS serta hubungan antara derajat keparahan DS dengan spesies Malassezia yang ditemukan. Metode: Studi potong lintang dilakukan di Jakarta dengan cara consecutive sampling. Pada subjek dilakukan anamnesis, pemeriksaan fisis, dan pengambilan sisik dari kulit kepala, kemudian ditumbuhkan pada CHROMagar Malassezia, sub kultur pada agar SDA, Tween-60-esculin, dan reaksi katalase. Hasil : Dari 59 spesimen dengan kultur positif, terdapat 72,1 SP dengan DS ringan dan 27,7 dengan DS sedang-berat. Distribusi M.globosa sebesar 52,1 , M.dermatis 23,2 , M.japonica 7,2 , M.pachydermatis 7,2 , M.sympodialis 2,8 , serta M.obtusa dan M.furfur masing-masing 1,4 dari total 69 isolat. Terdapat 4,3 isolat yang tidak teridentifikasi. Tidak didapatkan hubungan antara derajat keparahan DS dengan spesies Malassezia. Simpulan: M.globosa merupakan spesies Malassezia terbanyak yang diidentifikasi pada pasien DS di Indonesia. Perbedaan hasil dengan negara lain diduga terjadi akibat perbedaan cara identifikasi dan lokasi geografis. Spesies Malassezia tidak mempengaruhi tingkat keparahan DS.

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ABSTRACTBackground Malassezia sp. plays an important role in the pathogenesis of seborrheic dermatitis SD . In some countries, M. restricta and M. globosa are considered the predominant organisms on SD scalp. There is no data about Malassezia sp. in Indonesian SD scalp and its relationship with severity of illness. Objective To identify the distribution of Malassezia sp. of SD scalp and correlation between severity of SD with the Malassezia sp. Methods This cross sectional study conducted in Jakarta, using consecutive sampling. Anamnesis, clinical examination, and scrapping from the scalp were done to subject. Scales inoculated on CHROMagar Malassezia, Saboraud Dextrose Agar SDA , Tween 60 esculin agar, and catalase reaction.Results There were 72,1 mild SD and 27,7 moderate to severe SD. M.globosa was identified in 52,1 , M.dermatis in 23,2 , M.japonica in 8,7 M.pachydermatis in 7,2 , M.sympodialis 2,8 , while M.obtusa and M.furfur contributes 1,4 out of 69 isolates from 59 specimens with positive cultures. There is 4,3 unidentified isolates. Malassezia species was not related to severity of SD. Conclusion M.globosa is the predominant Malassezia species in Indonesian SD patients. This difference may be attributable to the identification techniques and geographical differences. Malassezia species not related to severity of SD."

"Latar belakang dan tujuan: Akne vulgaris AV merupakan inflamasi kronik pada unit pilosebasea. Beberapa penelitian telah meneliti kadar 25-hydroxyvitamin D [25 OH D] serum pada pasien AV dengan hasil bervariasi, namun umumnya rendah. Kadar vitamin D diduga terpengaruh oleh pajanan sinar matahari, letak geografis, ras/tipe kulit, dan asupan makanan, sehingga mungkin temuan di Indonesia akan berbeda daripada penelitian terdahulu di luar negeri. Penelitian ini bertujuan untuk mengetahui kadar 25 OH D serum dan hubungan dengan derajat keparahan, lesi inflamasi, noninflamasi, dan total lesi AV. Metode: Penelitian potong lintang ini melibatkan 30 subjek penelitian SP, direkrut secara consecutive sampling, terbagi rata ke dalam kelompok AV ringan AVR, AV sedang AVS, dan AV berat AVB berdasarkan klasifikasi Lehmann. Faktor risiko AV yang berkaitan dengan vitamin D pajanan sinar matahari, penggunaan tabir surya, suplementasi, jumlah lesi, dan kadar 25 OH D serum dinilai pada seluruh SP. Hasil : Median kadar 25 OH D serum pada kelompok AVR, AVS, dan AVB yaitu 16,3 9,1- 17,8 ng/mL, 12,7 9,6-15,6 ng/mL, dan 9,35 4,9-10,9 ng/mL Median pada kelompok AVR dan AVS lebih tinggi dibandingkan AVB.

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Background and objective: Acne vulgaris AV is chronic inflammation of pilosebaceous units. Several studies have investigated the levels of serum 25 hydroxyvitamin D 25 OH D in AV patients with varying outcomes, but mostly decreased. Vitamin D levels are thought to be affected by sun exposure, geographical location, race skin type, and food intake, that research in Indonesia may yield different results. This study aimed to determine the level of serum 25 OH D and its association with the severity and the number of inflammatory, noninflammatory, and total AV lesions.

Methods: This cross sectional study included 30 patients. Subjects were recruited by consecutive sampling, grouped equally into mild, moderate, and severe AV based on Lehmann's classification. The risk factors for inadequate vitamin D such as sun exposures, sunscreen, and suplements, the number of lesions, and serum 25 OH D levels were assessed on all subjects.

Results: The median concentrations of serum 25 OH D in the three groups were respectively 16.3 9.1 17.8 ng mL, 12.7 9.6 15.6 ng mL, and 9.35 4.9 10.9 ng mL p."

"[ABSTRAKLatar belakang dan tujuan: Akne vulgaris (AV) adalah penyakit peradangan menahun unit pilosebasea yang bersifat swasirna, ditandai dengan lesi pleomorfik berupa papul, komedo, pustul, dan nodul. Pengobatan AV memerlukan waktu yang cukup lama. Penyakit menahun dengan waktu pengobatan yang lama, berdampak terhadap kepatuhan pasien. Kepatuhan pengobatan topikal lebih rendah daripada sistemik. Hanya akne vulgaris ringan (AVR) yang diterapi menggunakan obat-obatan topikal saja. Layanan pesan singkat merupakan salah satu cara yang praktis dan efisien dalam upaya meningkatkan kepatuhan pengobatan AV, dengan pertimbangan prevalensi AV lebih banyak pada usia remaja dan dewasa muda yang merupakan pengguna terbanyak layanan tersebut. Dengan layanan ini, diharapkan pasien tidak lupa menggunakan obat topikal pada AVR. Penelitian ini dilakukan untuk mengetahui efektivitas penggunaan pesan singkat elektronik terhadap kepatuhan pengobatan AVR.Metode: Studi eksperimen dengan desain randomized controlled trial (RCT) terhadap pasien AVR usia 15-25 tahun yang berobat ke Poliklinik Ilmu Kesehatan Kulit dan Kelamin (IKKK) Rumah Sakit dr. Cipto Mangunkusumo (RSCM). Penelitian ini melibatkan 2 kelompok, yaitu: kelompok intervensi yang mendapat pesan singkat elektronik dan kelompok kontrol. Kedua kelompok diberi pengobatan tretinoin krim 0,05% dan/atau klindamisin gel 1,2% selama 6 minggu.Hasil: Tidak terdapat perbedaan bermakna antara kepatuhan pengobatan AVR kelompok kontrol dengan kelompok intervensi pada minggu kedua (p=0,376) dan keempat (p=0,432). Namun pada minggu keenam, kelompok intervensi secara bermakna lebih patuh daripada kelompok kontrol (p=0,032).Kesimpulan: Pesan singkat elektronik meningkatkan kepatuhan pengobatan AVR terutama pada minggu keenam di Poliklinik IKKK RSCM.

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ABSTRACTBackground and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy.Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks.Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032).Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronicinflammatory disease of pilosebaceous unit, characterized by pleomorphic lesionsconsist of papules, comedones, pustules, and nodules. Acne vulgaris requires along duration of treatment. Chronic disease with a long duration of therapyusually has an impact on adherence. Topical therapy adherence is lower thansystemic. Only mild AV is treated with topical medications. Electronic textmessaging is a practical and efficient method in order to improve adherence toAV therapy, with a consideration of the AV prevalence are more on teens andyoung adults who are the majority users of electronic text messaging service.With this method, patients are expected not to forget the use of medication. Thisstudy was conducted to determine the effectiveness of electronic text messagingto improve adherence of mild AV therapy.Methods: Experimental study, randomized controlled trial (RCT) to mild AVpatients, age 15-25 years old who came to Dermatology and Venereology Clinicdr. Cipto Mangunkusumo Hospital. This study involved two groups: interventiongroup who received electronic text messaging, and the contrary is the controlgroup. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapybetween both groups in the second (p = 0.376) and fourth week (p = 0.432). Theintervention group was significantly higher in terms of adherence than the controlgroup in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronicinflammatory disease of pilosebaceous unit, characterized by pleomorphic lesionsconsist of papules, comedones, pustules, and nodules. Acne vulgaris requires along duration of treatment. Chronic disease with a long duration of therapyusually has an impact on adherence. Topical therapy adherence is lower thansystemic. Only mild AV is treated with topical medications. Electronic textmessaging is a practical and efficient method in order to improve adherence toAV therapy, with a consideration of the AV prevalence are more on teens andyoung adults who are the majority users of electronic text messaging service.With this method, patients are expected not to forget the use of medication. Thisstudy was conducted to determine the effectiveness of electronic text messagingto improve adherence of mild AV therapy.Methods: Experimental study, randomized controlled trial (RCT) to mild AVpatients, age 15-25 years old who came to Dermatology and Venereology Clinicdr. Cipto Mangunkusumo Hospital. This study involved two groups: interventiongroup who received electronic text messaging, and the contrary is the controlgroup. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapybetween both groups in the second (p = 0.376) and fourth week (p = 0.432). Theintervention group was significantly higher in terms of adherence than the controlgroup in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital., Background and objectives: Acne vulgaris (AV) is a self limited, chronicinflammatory disease of pilosebaceous unit, characterized by pleomorphic lesionsconsist of papules, comedones, pustules, and nodules. Acne vulgaris requires along duration of treatment. Chronic disease with a long duration of therapyusually has an impact on adherence. Topical therapy adherence is lower thansystemic. Only mild AV is treated with topical medications. Electronic textmessaging is a practical and efficient method in order to improve adherence toAV therapy, with a consideration of the AV prevalence are more on teens andyoung adults who are the majority users of electronic text messaging service.With this method, patients are expected not to forget the use of medication. Thisstudy was conducted to determine the effectiveness of electronic text messagingto improve adherence of mild AV therapy.Methods: Experimental study, randomized controlled trial (RCT) to mild AVpatients, age 15-25 years old who came to Dermatology and Venereology Clinicdr. Cipto Mangunkusumo Hospital. This study involved two groups: interventiongroup who received electronic text messaging, and the contrary is the controlgroup. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin1,2% gel for six weeks. Results: There were no significant differences in adherence of mild AV therapybetween both groups in the second (p = 0.376) and fourth week (p = 0.432). Theintervention group was significantly higher in terms of adherence than the controlgroup in the sixth week (p = 0.032). Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.]"

"Dermatitis seboroik adalah inflamasi kronik dan superfisial yang bertempatpredileksi di area kulit dengan kandungan sebum yang banyak. Sampai saat ini,berbagai penelitian telah dikembangkan untuk mengetahui etiologi dan faktor yangmempengaruhi terjadinya dermatitis seboroik. Salah satu etiologi yang sering dikaitkan dengan kejadian dermatitis seboroik adalah kelenjar sebum. Produksi kelenjar sebum yang berlebih mempunyai kaitan dengan dermatitis seboroik. Pada penderita obesitas, aktivasi kelenjar sebasea akan mengalami peningkatan sehinggaterjadi produksi sebum yang berlebih. Sebum yang berlebihan tersebut dapat dicerna oleh jamur Malassezia spp pada kulit kepala sehingga menghasilkan asam lemak tidak jenuh yang dapat merusak lapisan kulit, terjadi hiperproliferasi, dan kembali meningkatkan sekresi sebum. Penelitian ini bertujuan untuk mengetahui korelasi antara indeks massa tubuh dengan skor keparahan dermatitis seboroik dikepala pada pasien Poliklinik Kulit dan Kelamin Rumah Sakit Dr Cipto Mangunkusumo Jakarta. Penelitian ini merupakan penelitian dengan metode potong lintang. Sejumlah 87 orang pasien DS yang memenuhi kriteria inklusi dantelah diseleksi dengan kriteria eksklusi dimasukan menjadi sampel penelitian dengan metode consecutive sampling. Pada pasien tersebut dilakukan pengukuran IMT dan pengukuran derajat keparahan dermatitis seboroik menggunakan Seborrheic Dermatitis Area and Severity Index SDASI. Dari hasil penelitian tersebut didapatkan nilai median IMT pada pasien DS sebesar 24,24 16,65 ndash; 41,09 dan nilai median skor keparahan dermatitis sebesar 2,25 0,25-21. Melalui uji korelasi Spearmann, tidak didapatkan korelasi antara IMT dengan keparahandermatitis seboroik p = 0,545, r= -0.066.

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Seborrheic dermatitis SD is a chronic and superficial inflammation that havepredilection area in high sebum containing skin. Nowadays, several studies hadbeen conducted to ascertain etiology and factors associatied with seborrheicdermatitis. One of the etiology is activity of sebum gland. The excessice sebumproduction may impact occurency of SD. In obesity patients, excessive sebumproduction occur due to increasing activities of sebaceous glands. In scalp,Malassezia spp will digest sebum, thereby producing unsaturated fatty acid. Thisunsaturated fatty acid can impair skin barrier, trigger hyperproliferation, and evenincrease sebum production.

This study was aimed to determine the correlation between Body Mass Index and Seborrheic Dermatitis Severity Scoring Index in Seborrheic Dermatitis Patient's Scalp at Dermato Venereology Outpatient Policlinic dr Cipto Mangunkusumo Hospital, Jakarta.

This was cross sectional study. A total of 87 SD patients who met the inclusion criteria and selection using exclution criteria were recruited by consecutive sampling. Body mass index was measured in all patient. Severity of SD was measured using Seborrheic Dermatitis Area and Severity Index SDASI. From 87 patients, the median of IMT was 24.24 16.65 41.09 and median of severity SD was 2.25 0.25 21.

The result from Spearmann correlation test showed that IMT has no correlation with scoring of SDseverity in scalp at Dermato Venereology outpatient policlinic dr Cipto Mangunkusumo Hospital p 0.545, r 0.066."

"Dermatitis seboroik merupakan masalah kulit kronis yang ditandai gejala berupa eritema, skuama, dan papul pada kulit yang memiliki banyak kelenjar sebasea. Dermatitis seboroik ringan sering disebut ketombe. Sampai saat ini, belum ada penelitian yang menjelaskan faktor pencetus keparahan dermatitis seboroik, salah satunya depresi. Depresi adalah gangguan mood kronis yang ditandai dengan menurunnya pola hidup dan ritme biologis seseorang yang muncul akibat stress psikologis kronis. Keduanya diperkirakan memiliki korelasi meski sampai saat ini belum ada penelitian yang menunjukkan hasil bermakna. Tujuan dari penelitian ini adalah mencari korelasi antara depresi dengan keparahan dermatitis seboroik. Penelitian ini dilakukan secara cross sectional di Departemen Ilmu Kulit dan Kelamin Rumah Sakit dr. Cipto Mangunkusumo, Jakarta pada 2017. Keparahan dermatitis seboroik diukur dengan Seborrheic Dermatitis Area and Severity Index SDASI , sementara depresi diukur dengan kuesioner Beck Depression Inventory II BDI-II. Subjek penelitian sebanyak 82 pasien dermatitis seboroik. Uji normalitas data ditemukan tidak normal. Nilai median depresi sebesar 5 0-38 dan nilai median keparahan dermatitis seboroik sebesar 2,25 0,25-21. Hasil uji korelasi dengan Spearman menunjukkan hasil tidak signifikan dan tidak ada korelasi antara depresi dengan keparahan dermatitis seboroik P=0,249 dan r=-0,129. Kesimpulan dari penelitian ini adalah tidak ditemukan adanya korelasi antara depresi dengan keparahan dermatitis seboroik.

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Seborrheic dermatitis is a chronic skin disease with specific manifestation such as erythematous, squamous, and papules on sebaceous glands rich skin. Mild seborrheic dermatitis usually recognized as dandruff. There were no previous studies that explained causal factors that affect seborrheic dermatitis severity, including depression. Depression is one of psychiatry disorders that affects mood chronically, changed lifestyle, and disturbed biological rythme which caused by chronic psychology stress. There were no studies that explained their correlation, despise the fact that there is relationship between emotional stress and dermatology disorders especially in neuroendocrine system that affects skin tissue homeostatic. This was a cross sectional research that applied in dermatology and venereology clinic dr. Cipto Mangunkusumo Hospital Jakarta in 2017 to find correlation between depression and seborrheic dermatitis severity. Seborrheic dermatitis severity measured by Seborrheic Dermatitis Area and Severity Index SDASI , and depression measured by Beck Depression Inventory II BDI II. The subjects were 82 seborrheic dermatitis patients. Median number for depression was 5 0 38 and median number for seborrheic dermatitis was 2.25 0.25 21. Correlation trials with spearman showed no statistically significant between depression and seborrheic dermatitis severity P 0.249 and r 0.129. Conclusion, this research showed there was no correlation between depression and seborrheic dermatitis severity."

"ABSTRAK Latar belakang. Infeksi human papillomavirus (HPV) pada genital laki-laki selain dapatmenyebabkan kutil kelamin dan kanker penis juga meningkatkan risiko infeksi HPV padapasangan. Walaupun saat ini telah terdapat banyak penelitian mengenai peran HPV risikotinggi terhadap karsinogenesis serviks dan semakin jelas peran laki-laki sebagai vektor virusHPV, namun pemeriksaan HPV pada laki-laki belum rutin dilakukan. Penelitian ini bertujuanmengetahui proporsi kepositivan, variasi genotipe HPV pada suami pasien kanker serviksserta kesamaan genotipe HPV antara suami pasien kanker serviks yang HPV positif denganpasien kanker serviks di RSUPN Dr Cipto Mangunkusumo. Metode. Penelitian potonglintang. Pemilihan SP dilakukan secara berurutan (consecutive sampling). Sampel diambildengan menggunakan kertas amplas dan dacron swab. Pada spesimen dilakukan pemeriksaanmenggunakan HPV express matrix Kalgen®. Hasil. Sebanyak 47 SP dilibatkan dalampenelitian ini, dengan rerata usia 50,7+10,6 tahun. Dari analisis spesimen diidentifikasi HPVgenital pada 9 (19%) SP, terdiri atas genotipe risiko rendah (3 SP) dan risiko tinggi (6 SP).Genotipe HPV yang ditemukan adalah 6, 18, 31, 39, 43, 53, dan 56, dengan tipe terseringadalah 18 dan 43. Tidak didapatkan kesamaan tipe HPV di antara pasangan HPV yangpositif. Kesimpulan. Proporsi kepositivan HPV pada suami pasien kanker serviks sebesar19% dengan tipe 18 dan 43 paling banyak didapatkan, namun tidak didapatkan kesamaan tipe HPV antara SP dengan pasien kanker serviks pasangannya.ABSTRACT Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse.;Background. Human papillomavirus (HPV) infection on male genital could cause genitalwarts, penile cancer, but also increase the risk of HPV infection in their spouse. Despitemany current researches on role of high-risk HPV in cervix carcinogenesis and male partner?srole as HPV vector is well known, HPV examination on male is not yet routinely performed.The aim of this study is to find the positivity proportion and genotype variant of HPV oncervical cancer patient?s spouse, and also the genotype concordance between the spouse withHPV positive and the cervical cancer patient at dr Cipto Mangunkusumo hospital. Method.Cross-sectional design. Subject was chosen consecutively (consecutive sampling). Samplewas collected with emery paper and dacron swab. The specimen was then analyzed with HPVexpress matrix Kalgen®. Result. Fourty seven subject enrolled in this studi with mean age50,7+10,6 y.o. Specimen analysis identified genital HPV on 9 (19%) subject, with low risk (3subject) and high risk (6 subject) genotype. HPV genotypes found in this study are 6, 18, 31,39, 43, 53, dan 56, with 18 and 43 as the most frequent. No genotype concordance foundbetween the cervical cancer patient?s spouse with HPV positive and their partners. HPVgenotypes variation found on cervical cancer?s spouses are type 6, 18, 31, 39, 43, 53, dan 56.Conclusion. The positivity proportion of HPV on cervical cancer patient?s spouse was 19%,with genotype 18 and 43 as the most frequent with no HPV genotype concordance found between subjects and the spouse."

"Dermatitis Seboroik DS merupakan kelainan inflamatorik kronik pada kulit dengan karakteristik plak eritematosa dan skuama kekuningan berminyak pada area tubuh yang banyak mengandung kelenjar sebasea, termasuk kulit kepala. DS umum terjadi pada 1-5 populasi dan menimbulkan dampak negatif terhadap kualitas hidup. Sekresi sebum, yang merupakan salah satu faktor DS, memiliki laju yang bervariasi sesuai dengan usia seseorang di mana mencapai puncak pada tiga bulan pertama kehidupan, masa pubertas, dan usia dewasa 30-60 tahun. Tujuan penelitian ini yaitu mengetahui korelasi usia dan skor keparahan DS. Penelitian ini menggunakan desain cross-sectional dan mendapatkan sampel dengan metode consecutive sampling sebanyak 87 pasien Poliklinik Kulit dan Kelamin RSCM. Usia diukur berdasarkan tanggal lahir pada kartu identitas dan skor keparahan DS diukur menggunakan seborrheic dermatitis area severity index SDASI. Berdasarkan uji normalitas data dan uji korelasi Spearmann yang dilakukan, didapatkan hasil yang menunjukkan bahwa korelasi usia dan skor keparahan DS tidak signifikan p=0,495 ; r=0,074. Rerata usia dalam median yaitu 29,25 12,67-69,75 tahun, sedangkan rerata skor keparahan DS dalam median yaitu 2,25 0,25-21.

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Seborrhoeic Dermatitis DS is a chronic inflammatory disorder on skin characterized by erythematous plaque and oily yellowish scales in areas of body with high sebaceous glands, including the scalp. DS occurs in 1-5 of the population and causes negative impact to quality of life. Sebum secretion, one of DS factors, has varrying rates according to age of a person, where the peak incidence is in first three months of life, puberty, and adult age 30 60 years.

Purpose of this study was to know the correlation between age and DS severity score. In this cross sectional study, consecutive sampling method was used and total subjects were 87 patients of Poliklinik Kulit dan Kelamin RSCM. Age was obtained based on date of birth on identity card and DS severity score was measured by seborrheic dermatitis area severity index SDASI.

Based on normality test and Spearmann test which had been done, the result showed that there was no significant correlation between age and DS severity score p=0.495 ; r=0.074. Age in median was 29.25 12.67-69.75 years, while the mean DS severity score in the median was 2.25 0.25-21."

"Latar Belakang Penyakit kusta adalah penyakit infeksi kronik yang disebabkan oleh Mycobacterium leprae. Kusta menyebabkan gangguan fisik, psikologik, dan sosial, yang menurunkan kualitas hidup penderita. Deformitas yang terlihat pada pasien kusta adalah salah satu penyebab utama stigma yang mempengaruhi perilaku pencarian kesehatan dan inklusi sosial. Oleh karena itu, penelitian ini dilakukan untuk mengetahui profil bentuk dan derajat kecacatan pada pasien kusta di Poliklinik Dermatologi dan Venereologi. Metode Penelitian dilakukan secara retrospektif terhadap data pasien kusta di Rumah Sakit Dr. Cipto Mangunkusumo selama periode Januari 2022 - September 2023 dengan variabel penelitian, yaitu usia, jenis kelamin, klasifikasi, bentuk dan derajat cacat, serta tindak lanjut pengobatan cacat kusta. Hasil Pada 83 subjek penelitian, didapatkan paling banyak pasien pada kelompok usia dewasa dengan jenis kelamin laki-laki dan tipe multi basiler. Ditemukan paling banyak pasien dengan cacat kusta dengan didominasi pasien cacat tingkat 1. Frekuensi paling banyak cacat pada ekstermitas atas dan/atau bawah. Tindak lanjut pengobatan pasien cacat kusta menunjukan paling banyak pasien yang tidak dirujuk balik. Kesimpulan Didapatkan profil pasien kusta terkait bentuk dan derajat kecacatan di Rumah Sakit Dr. Cipto Mangunkusumo. Terdapat rekam medis yang tidak lengkap terhadap pemeriksaan cacat pada pasien kusta.

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Introduction Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Leprosy causes physical, psychological and social disorders, which reduce the quality of life. The deformities seen in leprosy patients are one of the main causes of stigma that influences health-seeking behavior and social inclusion. This research was conducted to determine the profile of the shape and degree of disability in leprosy patients at the Dermatology and Venereology Polyclinic. Method This research was conducted retrospectively on data from leprosy patients at Dr. Cipto Mangunkusumo during the period January 2022 - September 2023 with research variables, namely age, gender, classification, shape and degree of disability, and the follow-up treatment. Results In the 83 research subjects, the majority of patients were in the adult age group with male gender and multi bacillary type. The highest number of patients with leprosy defects were found, with the majority being patients with grade 1 defects. The highest frequency of defects was in the upper and/or lower extremities. Follow-up treatment of disabled leprosy patients showed that most patients were not referred back. Conclusion Profiles of leprosy patients were obtained regarding the form and degree of disability at Dr. Cipto Mangunkusumo. There are incomplete medical records regarding examinations of defects in leprosy patients."