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"The “always on-hand” pocket guide to the treatment of infectious diseases.- The most important antibiotics and antimycotics :Spectrum – dosage – side-effects- Numerous tables sorted by substances, pathogens, indications- Administration of antibiotics during pregnancy, renal and hepatic insufficiency, dialysis- Including statements on the cost of therapyNumerous tips and troubleshooting guides on topics such as :- Potential mistakes- Therapy failures- Perioperative antibiotic prophylaxisAdjusted to European standards :Up-to-date substances, authorizations, resistances and trade names."

"Antibiotik profilaksis adalah antibiotik yang digunakan untuk mencegah terjadinya infeksi. Antibiotik yang biasa digunakan memiliki spektrum sempit, toksisitas rendah, memiliki sifat bakterisidal dan spesifik. Tujuan penelitian ini adalah melihat kesesuaian penggunaan antibiotik profilaksis pada pasien yang dilakukan pembedahan di Instalasi Bedah Sentral RSUP Fatmawati periode Januari ndash; Maret 2017 dengan PPAB RSUP Fatmawati tahun 2016 dan ASHP Guidelines tahun 2013. Metode penelitian ini dilakukan secara deskriptif analitik dengan pengambilan data secara retrospektif. Pengambilan sampel dengan teknik total sampling. Pasien yang paling banyak dilakukan pembedahan adalah pasien perempuan 57,54 dan kelompok usia yang paling banyak adalah >45-55 tahun. Rencana pembedahan yang paling banyak dilakukan adalah elektif 73,75 . Divisi pembedahan yang paling banyak dilakukan adalah bedah kebidanan 20,37 . 2.191 pasien mendapatkan antibiotik profilaksis sebelum pembedahan dan persentase divisi pembedahan yang paling banyak menggunakan antibiotik profilaksis adalah bedah digestif 89,15 . Antibiotik profilaksis yang paling banyak digunakan adalah penggunaan tunggal sefazolin 41,05 . Kesesuaian penggunaan antibiotik profilaksis dengan PPAB RSUP Fatmawati tahun 2016 sebesar 51,92 dan kesesuaian penggunaan antibiotik profilaksis dengan ASHP Guidelines 2013 sebesar 43,13.

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Prophylactic antibiotics are antibiotics used to prevent infection. Commonly used antibiotics have a narrow spectrum, low toxicity, have a bactericidal activity and specific. The purpose of this study is to see the suitability of the use of prophylactic antibiotics in surgical patients at the Central Surgery Installation of Fatmawati Central General Hospital January March 2017 with Antibiotic Guidelines from Fatmawati Central General Hospital 2016 and ASHP Guidelines 2013. This research method is done analitical descriptively with retrospective retrieval data. Sampling with total sampling technique. Patients most widely performed surgery were female 57.54 and the age group most was 45 55 years. The most widely performed surgical plan was elective 73.75 . The most widely performed surgical division was midwifery surgery 20.37 . 2,191 patients received prophylactic antibiotics before surgery and surgery division percentage of the most widely used surgical antibiotic prophylaxis was digestive 89.15 . The most widely used prophylactic antibiotic is cefazoline 41.05 . The compliance of prophylactic antibiotic usage with Antibiotic Guidelines from Fatmawati Central General Hospital 2016 was 51,92 and compliance of antibiotic prophylaxis with ASHP Guidelines 2013 was 43,13."

"The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed."

"Summary: "Learn all you need to know about gastrointestinal drugs and their clinical use with this one-stop, rapid reference pocket guide. Brought to you by many of the world’s leading GI drug experts, Pocket Guide to Gastrointestinal Drugs provides comprehensive guidance to the pharmacological properties of drugs used to treat gastrointestinal conditions, including mechanisms of action, appropriate administration, and potential adverse effects associated with their use. Organized by class of drug and ranging from PPIs to immunosupressants, each chapter first examines the specific agents within that class and then their appropriate and judicious use across a range of specific GI disorders. Key features include: - Introduction of drug class, - Basic pharmacology, including mechanism of action, bioavailability, metabolism, interactions, adverse effects, toxicity, and special considerations, - Dosing information for each GI condition and on- and off-label use, - Consistent use of both generic and trade names throughout, - Specific reference to drug use in pediatric patients and during pregnancy. Perfect for quick consultation on the wards and in the office, Pocket Guide to Gastrointestinal Drugs is the ideal tool for all those managing patients with GI conditions, including gastroenterologists, GI trainees, emergency physicians, GI specialist nurses, primary care physicians and residents, intensivists and pharmacists"--Provided by publisher.Contents: Machine generated contents note: Section I: Upper GI Tract1 Prokinetic agents and antiemetics / Hemangi Kale and Ronnie Fass -- 2 Proton pump inhibitors / Wanda P. Blanton and M. Michael Wolfe -- 3 Histamine H2-receptor antagonists / Kentaro Sugano -- 4 Prostaglandins and other mucosal protecting agents / Carlos Sostres and Angel LanasSection II: Small and Large Intestine -- 5 5-HT Modulators and other anti-diarrheal agents and cathartics / Albena Halpert and Douglas Drossman -- 6 5-Aminosalicylates / Hannah L. Miller and Francis A. Farraye -- 7 Immunosuppressive agents / Lev Lichtenstein and Gerald M. Fraser -- 8 Biological agents / Gert Van AsscheSection III: Liver and Pancreas -- 9 Interferons / Robert C. Lowe -- 10 Nucleoside analogues / David P. Nunes -- 11 Ursodeoxycholic acid and chelating agents / James Dooley -- 12 Agents for the treatment of portal hypertension / Karen L. Krok and Andres Cardenas -- 13 Pancreatic enzymes / Steven Czinn and Samra S. Blanchard -- Section IV: Antimicrobials and Vaccines -- 14 Antibiotics for the therapy of gastrointestinal diseases / Melissa Osborn -- 15 Antimicrobials for parasitic diseases / Joachim Richter -- 16 Vaccines for Viral Hepatitides / Savio John and Raymond T. Chung -- 17 Rotavirus and Other Enteric Vaccinations / Christopher J. Moran and Esther Israel -- Section V: Nutrition and Probiotics -- 18 Parenteral and enteral nutrition feeding formulas / Dominic N. Reeds and Beth Taylor -- 19 Probiotics / Christina M. Surawicz."

"This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large bacterial resistome which is a collection of all resistance genes and their precursors in both pathogenic and non-pathogenic bacteria. Ongoing resistance surveillance programs are also discussed, together with the perspective of a clinical microbiologist. The book then turns to specific themes such as the most serious area of resistance in pathogens, namely in Gram-negative organisms. The role of combinations of antibiotics in combating resistance emergence is discussed, particularly in the tuberculosis field, and then the importance of non-multiplying and persistent bacteria which are phenotypically resistant to antibiotics and prolong the duration of therapy of antibiotics which leads to poor compliance and resistance emergence. The role of anti-microbial compounds in textiles is covered, with its potential to exacerbate the spread of resistance. Then, efflux pumps are discussed. The final chapter describes the compounds which are in late stage clinical development, illustrating the paucity of the antibiotic pipeline, especially for Gram-negative bacteria."

"The book starts with four chapters in which the potential, advantages, and phylogeny of enzybiotics are reviewed. Then, the new ways of controlling infections by Gramnegative bacteria and an updated view of bacteriophage holins are presented. After a review of antistaphylococcal lytic enzymes, the book goes on to discuss membrane targeted enzybiotics, as well as the design of phage cocktails for current therapy. Finally, the last two chapters deal respectively with the novel methods to identify new enzybiotics and the use of modified phages to induce suicide in bacteria.Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores :- A new approach to controlling infections using Gram-negative bacteria- Bacteriophage holins and their membrane-disrupting activity- Anti-staphylococcal lytic enzymes- Membrane-targeted enzybiotics- Design of phage cocktails for therapy from a host-range point of view- Novel methods to identify new enzybiotics- Genetically modified phages that deliver suicidal genes to target bacteriaThe authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.As more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics."

"La terapia antibiotica è un campo della medicina in continua evoluzione ed è al centro di dibattiti sempre vivi. Tema assai delicato, oggi più che mai, è l’importanza di un uso calibrato e razionale degli antimicrobici che limiti il rischio di resistenze batteriche e preservi l’efficacia delle cure. La comparsa di nuovi patogeni ha spinto la comunità scientifica a riconsiderare molti aspetti delle terapie, e proprio di tutte queste novità il volume fornisce un attento aggiornamento.Per facilitare la consultazione questa guida raggruppa le informazioni secondo diversi criteri di ricerca: per distretti corporei, per tipologia di microbo e per classi di farmaci. In questo modo il medico, a seconda delle circostanze, può trovare rapidamente i dettagli essenziali dei diversi farmaci e deciderne l’impiego più opportuno. Completa il volume anche una sezione sul controverso tema degli antibiotici in gravidanza."