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"Principles of toxicology : environmental and industrial applications, this edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields. Principles of toxicology, second edition features :

• - Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems
• - Coverage of occupational medicine and epidemiological issues
• - The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins
• - Special emphasis on the evaluation and control of toxic hazards
• - Specific case histories on applying risk assessment methods in the modern workplace
• - Ample figures, references, and a comprehensive glossary of toxicological terms

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"This first comprehensive survey to cover all pharmaceutically relevant topics provides a comprehensive introduction to this novel and revolutionary tool, presenting both concepts and application examples of biosimulated cells, organs and organisms.Following an introduction to the role of biosimulation in drug development, the authors go on to discuss the simulation of cells and tissues, as well as simulating drug action and effect. A further section is devoted to simulating networks and populations, and the whole is rounded off by a look at the potential for biosimulation in industrial drug development and for regulatory decisions.Part of the authors are members of the BioSim Network of Excellence that encompasses more than 40 academic institutions, pharmaceutical companies and regulatory authorities dealing with drug development; other contributors come from industry, resulting in a cross-disciplinary expert reference."