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"Kolesterol yang tinggi dalam darah merupakan faktor resiko dari aterosklerosis yang menyebabkan berbagai penyakit. Intervensi farmakologik utama untuk mengurangi kadar kolesterol ialah menghambat enzim HMG-KoA reduktase. Salah satu tanaman dari marga Garcinia, yakni Garcinia dulcis memiliki potensi sebagai aktivitas antikolesterol. Berdasarkan kemotaksonomi, Garcinia latissima Miq. diperkirakan juga mempunyai potensi aktivitas antikolesterol.Penelitian ini bertujuan untuk menguji penghambatan aktivitas HMG-KoA reduktase ekstrak air daging buah G.latissima dengan perbedaan durasi infusa, serta penetapan kadar flavonoid total dan fenol total pada ekstrak. Selain itu, simplisia daging buah G. latissima Miq. akan dibuat dalam bentuk teh dan dilakukan uji hedonis untuk mengetahui tingkat kesukaan masyarakat pada teh tersebut.Hasil uji menunjukkan ekstrak air daging buah G. latissima Miq 100 ppm dengan infusa selama 5, 10 dan 15 menit menghambat aktivitas enzim HMG-KoA reduktase berturut turut sebesar 11,32; 29,02; 13,03%. Ekstrak 10 menit dengan penghambatan enzim terbesar memiliki kadar flavonoid total sebesar 31,24 mg QE/gram ekstrak dan kadar fenol total sebesar 4,64 mg GAE/gram ekstrak. Sedangkan kesukaan masyarakat terhadap warna, aroma, rasa teh celup formula A buah G. latissima Miq. berturut turut sebesar 30; 30; 20% dan terhadap formula B berturut turut sebesar 40; 33,3; 50%.

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High cholesterol in the blood is a risk factor of atherosclerosis that causes various diseases. The main pharmacologic intervention to reduce cholesterol levels is inhibiting the HMG-CoA reductase enzyme. One of the genera of Garcinia, Garcinia dulcis, has potential as an anticholesterol. Based on chemotaxonomy, Garcinia latissima Miq. is also estimated to have a potency as anticholesterol.This study aims to test the inhibition activity of HMG-CoA reductase from mesocarp water extract of G.latissima with different duration of infusions, as well as determination of total flavonoid and total phenol content in the extract. In addition, the simplicia of the mesocarp of G. latissima Miq, will be made as herbal tea and a hedonic test is performed to find out the degree of liking for the tea.The test results showed inhibitory activity of 100 ppm G. latissima Miq. mesocarp water extract with infusion for 5, 10 and 15 minute repectively 11.32; 29.02; 13.03%. The 10 minute extract with the largest enzyme inhibition had total flavonoids content of 31.24 mg QE / gram extract and total phenol content of 4.64 mg GAE / gram extract. The result of hedonic test for the color, aroma, flavor of herbal tea formula A respectively 30; 30; 20% and formula B respectively for 40; 33.3; 50%."

"Despite the great success of WTO dispute settlement,a close examination of current WTO remedies has been continued to point out a variery of potential shortcomings such as ineffective compiliance,inadequate remedies and inequitable consequences of retaliation

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"ABSTRAKTesis ini membahas tentang penggunaan jamu untuk pengobatan pada pasien diKlinik Saintifikasi Jamu Hortus Medicus Tawangmangu tahun 2012. Penelitianini adalah penelitian kualitatif menggunakan pendekatan Rapid AssesmentProcedures (RAP). Hasil penelitian menemukan bahwa jamu yang digunakanuntuk pengobatan sudah dirasakan manfaatnya dengan efek samping yang ringan,serta jamu yang paling banyak digunakan adalah sediaan godokan. Hal yangmendukung penggunaan jamu untuk pengobatan adalah pengetahuan terhadaptanaman obat, persepsi terhadap jamu, informasi mengenai klinik dan fasilitaspelayanan yang tersedia, keterjangkauan akses, adanya keluhan sakit sertakeinginan untuk sembuh. Saran dari penelitian ini perlunya edukasi kepadamasyarakat dan penambahan Klinik Saintifikasi Jamu yang terjangkau

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ABSTRACTThis thesis discusses the use of Jamu for treatment on patients at The HortusMedicus Jamu Scientification Clinic in 2012. The study was a qualitative researchusing Rapid Assessment Procedures (RAP) approach. The study found that Jamumedicine used for treatment has already felt the benefit with low side effects, aswell as the most widely used Jamu preparations is boiling. Factors encouraged theuse of Jamu medicine for treatment are the knowledge of medicinal plants, Jamuperception, the availability of information on clinical and service facilities, theaffordability of access, the pain complaints and the desire to recover. There is aneed to educate people and increasing an affordable Jamu Scientification Clinic"

""This small paperback provides a very useful introduction to herbal medicine and includes contributions from twelve specialist authors, eight of whom are based in the UK. The eight chapters cover precisely the sorts of questions that any therapist would ask about any treatment. These include: How does it work? What can be learnt from its history? Is it safe? Should it be regulated? and How does it compare to other therapies?All these matters are discussed and the available evidence is clearly presented. Specific examples of individual herbs are given, including plants such as Angelica, Arnica, Echinacca, Feverfew, Ginko, Ginseng, Saw Palmetto, Saint John s Wort and Valerian."Acupuncture in Medicine, June 2002small book offers an evidence based look at herbal medicine that will serve as a useful introductory guide for physicians, herbalists and other healthcare professionals with an interest in plant based therapy, and also healthcare policy makers, herbal product manufacturers and medical educators."CAB Abstracts, May 2000"

" ABSTRAKInfeksi virus Dengue DENV masih menjadi masalah kesehatan global terutama didaerah tropis dan subtropis termasuk di Indonesia. Sampai saat ini belum ditemukanvaksin dan antiviral yang efektif untuk mencegah dan mengobati infeksi DENV.Ekstrak daun mengkudu Morinda citrifolia Linn diketahui memiliki efekmenghambat infeksi beberapa jenis virus dan bakteri. Penelitian ini bertujuan untukmengetahui kemampuan ekstrak daun Morinda citrifolia Linn pada konsentrasi 20 g/ml, 10 g/ml, 5 g/ml, 2,5 g/ml, dan 1,25 g/ml dalam menghambatpertumbuhan DENV2 pada sel Huh-7,5 yang diinfeksi DENV2 dengan multiplicityof infection 0,5. Fokus virus yang terbentuk divisualisasi melalui immunoassay danjumlah fokus antara kelompok perlakukan dibandingkan dengan kelompok kontrolpositif berupa sel Huh-7.5 yang terinfeksi DENV2 tanpa penambahan ekstrak daunMorinda citrifolia Linn. Secara statistik, pemberian ekstrak daun mengkudu dengankonsentrasi 1,25 ?g/ml memberikan hasil penghambatan yang signifikan p 0,05 .Kata kunci: DENV2, mengkudu Morinda citrifolia Linn , replikasi virus

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ABSTRAKDengue viral infection remains become one of the global health burden particularlyin tropical and subtropical area include in Indonesia. Till nowadays there is nospecific vaccine and antiviral to prevent and cure Dengue viral infection. Morindacitrifolia Linn leave extract has been known has the antiviral and antibacterialactivity. This research is aimed to know the effects of Morinda citrifolia Linn leavesextract in five different concentrations 20 g ml, 10 g ml, 5 g ml, 2,5 g ml, and1,25 g ml in inhibiting the replication of DENV2 on Huh 7.5 cells infected byDENV2 with multiplicity of infection 0,5. Foci that formed is visualized byimmunoassay and the amount of foci in each group is compared to positif controlthat Huh 7.5 cells is infected by DENV2 without addition of Morinda citrifolia Linnleaves extract. Statistically, addition 1,25 g ml of Morinda citrifolia Linn leaveextract shows significant inhibiting result p 0,05 .Key Words DENV2, Morinda citrifolia Linn, viral replication"

"Tesis ini merupakan bagian dari riset tentang the sociology of markets of Indonesian traditional medicine  (jamu) (Hardjosoekarto et al, forthcoming), khususnya yang menyajikan laporan awal tentang dinamika pasar obat tradisional di Indonesia dengan menggunakan konsep market field dari Jense Beckert, yang menekankan interelasi tiga social forces yaitu institutions, networks dan cognitive frames. Studi ini fokus pada respons Koperasi Jamu Indonesia (KOJAI) terhadap peng-ilmiahan Jamu yang dimulai sejak tahun 2007. Social Network Analysis diterapkan untuk mengukur perubahan KOJAI networks, baik pada level makro maupun pada level meso.  Ekplorasi kualitatif perubahan dua KOJAI social forces lainnya, yaitu institutions dan cognitive frames dilakukan pada level meso. Riset ini menyajikan bukti berlakunya Beckertss social grid model dengan pengayaan beberapa novelties. Pertama, dinamika interrelasi tiga social forces itu dapat terjadi di level meso yaitu pada level KOJAI as organizational field. Kedua, stabilitas dan perubahan organizational field itu dapat terjadi karena adanya dinamika internal di dalam organisasi itu sendiri, tetapi dapat juga berlangsung karena adanya perubahan external seperti perubahan institutional rules pada tingkat makro. Ketiga, riset ini juga menyajikan aplikasi Social Network Analysis untuk mengukur network as a market forces, sebuah pengukuran market field yang tidak dilakukan oleh Beckert. Hasil penelitian menunjukkan bahwa, jamu kurang berkembang karena, banyak regulasi yang memperkecil pengaruh dari aktor bisnis, baik itu pelaku usaha jamu maupun petani dalam mendapatkan dominasi nya di market field. Dominasi market field lebih banyak dilakukan oleh aktor dari Pemeritah, namun tetap belum memberikan hasil signifikan dalam pengembangan jamu. Oleh sebab itu, perlu adanya penguatan untuk para pelaku usaha industri yang memiliki keterbatasan modal dalam merealisasikan pemenuhan CPOTB. Sebagai stategi efektif, penelitian ini memberikan saran untuk memobilisasi cognitive frame bahwa proses produksi jamu tidak bisa disamakan dengan proses produksi obat kimia melalui konstruksi pada sisi institusional dan network struktur berdasarkan dari pemikiran Beckert (2010).

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This thesis is a part of research on the sociology of markets of Indonesian traditional medicine (jamu) (Hardjosoekarto et al, forthcoming), specifically which presents a preliminary report on the dynamics of the traditional medicine market in Indonesia by using the market field concept from Jense Beckert, which emphasizes the interrelation of three social forces namely institutions, networks and cognitive frames. This study focuses on the response of the Indonesian Herbal Cooperative (KOJAI) to the knowledge of herbal medicine that began in 2007. Social Network Analysis is applied to measure changes in KOJAI networks, both at the macro level and at the meso level. Qualitative exploration of changes in two other KOJAI social forces, namely institutions and cognitive frames is carried out at the meso level. This research presents evidence of the validity of Beckerts's social grid model with the enrichment of several novelties. First, the dynamics of the interrelation of the three social forces can occur at the meso level, namely at the KOJAI as organizational field level. Second, stability and organizational field changes can occur due to internal dynamics within the organization itself, but can also take place due to external changes such as changes in institutional rules at the macro level. Third, this research also presents a Social Network Analysis application to measure network as a market forces, a measurement of market fields that Beckert did not do. The results showed that, herbal medicine was underdeveloped because, there were many regulations that reduced the influence of Bussines actors, both herbal and farmer entrepreneurs in getting their dominance in the market field. Market field domination is mostly done by actors from the Government, but still does not provide significant results in the development of herbal medicine. Therefore, it is necessary to strengthen for industrial businesses that have limited capital in realizing the fulfillment of CPOTB. As an effective strategy, this study provides suggestions for mobilizing cognitive frames that the process of herbal medicine production cannot be equated with the process of producing chemical drugs through construction on the institutional and network structures based on the thought of Beckert (2010)."