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"Lesi tuberkulosis dapat terjadi bersamaan dengan keganasan sehingga menyulitkan diagnosis. Satu kasus karsinoma usus besar yang bersamaan dengan lesi tuberkulosis di tempat yang sama dilaporkan. Pasien telah menyelesaikan terapi anti tuberkulosis dan saat ini sedang menjalani kemoterapi reguler. Sampai saat ini keadaan umum pasien baik. (Med J Indones 2004; 14: 128-30)

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Tubercular lesion may coexist with malignancy in various sites resulting in difficulties in diagnosing the conditions. A case of carcinoma caecum associated with tubercular lesion in the same site is reported. The patient have completed the antitubercular therapy and is now on regular anticancer chemotherapy. Till now the patient is doing fine. (Med J Indones 2004; 14: 128-30)"

"AbstrakA 43-year old male presented with persistent discomfort and pain upper abdomen (epigastrium) more on left side associated with fever on and off, along with fatigue and loss of appetite for the last four months. Physical examination revealed mass on left hypochondrium extending to epigastrium with mild distension of the abdomen. Imaging studies of the patient showed dextrocardia on chest x-ray postero-anterior (PA) view, thoracic and abdominal CT scan showed situs inversus totalis with multiple SOL (space occupying lesion) in right lobe of liver with largest measuring 8x6 cm2 in the 4th segment. USG-guided FNAC of the mass showed features of hepatocellular carcinoma. Thereupon, hepatocellular carcinoma in situs inversus totalis was diagosed to this patient and was clinically staged as T3aN0M0. He was given sorafenib 400 mg orally twice daily with an advice to come for regular assessment every 4 week."

"Ameloblastoma merupakan jenis tumor odontogenik yang umumnya jinak. Namun demikian, kurang dari 2% kasus ameloblastoma mengalami metastasis, terutama ke paru. Kami melaporkan satu kasus ameloblastik karsinoma dengan metastasis di kedua paru setelah 10 tahun pasca reseksi tumor primer dan 2 tahun pasca kemoterapi.

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AbstractAmeloblastoma is a type of odontogenic tumor and generally considered as a benign tumor. However, less than 2% of ameloblastoma were found to have metastases, mostly to the lung. We reported a case of 46-year-old man presenting with an ameloblastic carcinoma with lung metastases 10 years after the primary tumor was resected and 2 years after chemotherapy. Keywords: ameloblastoma, chemotherapy, radiation."

"Nasopharyngeal carcinoma (NPC) is still a significant health problem due to its relatively high incidence. Rarely, NPC could extend and involve the oral cavity, and may present as an ulceration or exophytic mass. Objectives: To discuss the rare clinical appearance of NPC involving the oral cavity and the significant role of dentists in its diagnosis and management. Case Report: We reported 3 cases of NPC with oral cavity involvement. In the first two cases, the patients presented with persistent oral ulceration with bone exposure and perforation to the above structure. The third patient presented with an ulcerated exophytic mass with temporomandibular disorder. The ulceration occurred due to bone destruction by the expansion of NPC mass, which indicated advance stage of the disease. All patients were managed with twice a day 0.2% chlorhexidine gluconate rinsing in combination with placing a chlorhexidine-moistened gauze to inhibit bacterial overgrowth and prevent secondary infection. The use of chlorhexidine was substituted by saline solution during patients’ radiotherapy and chemotherapy cycles. Conclusion: Dentist’s awareness to recognize the oral cavity involvement of NPC as well as recognizing the symptoms of NPC is very important, in order to make appropriate diagnosis and oral management. The oral management will eventually affect treatment outcome and quality of life."

"ABSTRACTAlthough basal cell carcinoma (BCC) is a common skin tumor, very rare cases of BCC arising from upper vermilion mucosa of lip have been reported previously. This tumor basically, originates from pillar structures and the involvement of the vermilion lip contrasts this concept so it is devoid of hair follicles and sweat glands. The exact pathogenesis of vermilion lip BCC is not clear but it has been postulated that the neoplasm originates from the pluripotential epithelial cells of the oral mucosa and epidermis. On the other hand, some authors consider their origin from ectopic sebaceous glands. Herein, we report a 34- year-old man with an asymptomatic ulcerated lesion on the upper left lip vermilion mucosa .The diagnosis of BCC was confirmed with histopathological examination after incisional biopsy of the mucosal neoplasm. After surgery of lip lesion, no recurrency was seen after 3 months follow-up the patient."

"Karsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen

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AbstractKarsinoma paratiroid merupakan neoplasma yang jarang ditemukan, dengan frekuensi kurang dari 1% dari seluruh kasus hiperparatiroidisme primer. Beberapa gambaran klinis dan biokimiawi dapat mengarahkan pada karsinoma paratiroid namun diagnosis pre dan intraoperatif yang akurat masih sulit ditegakkan. Studi ini melaporkan satu kasus karsinoma paratiroid yang terdiagnosis pasca-operasi. Intraoperatif ditemukan pembesaran kelenjar paratiroid yang telah menginfiltrasi laringeus rekuren dan kelenjar tiroid kanan. Hasil histopatologik menunjukkan nodul tumor yang dipisahkan oleh jaringan ikat tebal, disertai invasi pada kapsul dan jaringan sekitar. Diagnosis akhir karsinoma paratiroid ditegakkan berdasarkan gambaran klinis dan pemeriksaan spesimen"

"Periosteal osteosarkoma merupakan tumor ganas tulang yang jarang didapat, dibentuk dari sarkoma tulang dengan didominasi komponen tulang rawan yang berdiferensiasi dan tumbuh pada permukaan tulang. Penelusuran kepustakaan tidak banyak menyebutkan mengenai kasus ini. Laporan kasus ini terakhir dilaporkan oleh Klinik Mayo tahun 1999. Kami laporkan satu kasus periosteal osteosarkoma pada penderita laki-laki berusia 17 tahun. Penderita menjalani tindakan pembedahan berupa prosedur ?limb salvage?, dengan pra dan pasca bedah penderita mendapat kemoterapi (neo-ajuvan dan ajuvan). Tidak ditemukan rekurensi lokal dan metastasis di paru, pada follow up sampai dengan 14 bulan pasca bedah. (Med J Indones 2003; 12: 166-70)

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Periosteal osteosarcoma is a rare type of malignant bone neoplasm, with predominantly cartilaginous component and arising on the bone surface. Reports of the case in the literature were rare. Last case was reported by Mayo Clinic in 1999. We report a case of periosteal osteosarcoma in a 17-year-old male, who was treated surgically with a limb salvage procedure, neoadjuvant and adjuvant chemotherapy were also given to the patient. There was no local recurrence and lung metastases up to 14 months after surgery. (Med J Indones 2003; 12: 166-70)"

"Penganiayaan anak merupakan masalah sosial dan masalah medis yang penting dan dapat menyebabkan kecacatan dan kematian pada anak. Angka kejadian penganiayaan anak dalam setahun diperkirakan sekitar 15 sampai 42 kasus diantara 1000 anak dan terdapat kecenderungan peningkatan. Patah tulang merupakan tanda klinis kedua terbanyak yang ditemukan setelah lesi kulit, dan sekitar sepertiga anak yang teraniaya akan mendatangi ahli bedah tulang. Kami melaporkan seorang anak laki-laki berusia 7 bulan yang diduga mengalami penganiyaan anak. Diagnosis kami didasarkan pada temuan patah tulang multiple, keterlambatan dalam mencari pertolongan medis dan perbedaan antara riwayat perjalanan penyakit dengan temuan klinis. Anak tersebut mengalami patah tulang multipel dengan proses penyembuhan yang bervariasi, termasuk patah tulang pada suprakondilar humerus kiri, radius dan ulna kiri, radius dan ulna kanan, kedua tulang femur, tibia kanan serta tibia dan fibula kiri. Pemeriksaan radiologis merupakan modalitas yang penting dalam menegakkan kemungkinan adanya penganiayaan pada anak tersebut. Anak tersebut telah mendapatkan penanganan medis, proteksi, kelompok konsultasi untuk kedua orang tua dan sedang dalam penyelidikan pihak kepolisian. (Med J Indones 2004; 13: 59-65)

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Child abuse is a pervasive social and medical problem that remains a major cause of disability and death among children. The annual incidence of abuse is estimated to be 15 to 42 cases per 1,000 children and appears to be increasing. Fractures are the second most common presentation of physical abuse after skin lesions, and approximately one third of abused children will eventually be seen by an orthopedic surgeon. We report a 7-month-old boy who was suspected to be abused. Our diagnosis was based on findings of multiple fractures, delay in seeking medical treatment and discrepancy between the history of illness and the clinical findings. He sustained multiple fractures in variety of healing, namely fractures on left supracondylar humeri, left radius and ulna, right radius and ulna, both femora, right tibia, and left tibia and fibula. Radiological examination was an important modality in revealing the possibility of abuse on this child. He had received medical treatment, protection, consultation team for the parents and an underway police investigation. (Med J Indones 2004; 13: 59-65)."