Praktik Spesialis Keperawatan merupakan sebuah proses penting dari pendidikan profesi dalam rangka mengaplikasikan peran perawat spesialis yang berdampak pada upaya peningkatan kualitas pelayanan keperawatan. Praktik ini dilakukan dan dikembangkan berdasarkan ilmu pengetahuan dan teknologi melalui berbagai penelitian. Model Virginia Henderson dan Teori Sosial Kognitif Bandura di RS Fatmawati Jakarta. Tiga kompetensi yang harus dicapai dalam praktek residensi ini adalah memberikan asuhan keperawatan menggunakan pendekatan teori keperawatan, menerapkan implementasi keperawatan yang berbasis bukti ilmiah (Evidence Based Nursing practice), dan melakukan proyek inovasi keperawatan yang berguna bagi lahan yang menjadi tempat praktek residensi.Sebagai pemberi asuhan keperawatan, mahasiswa residensi telah memberikan asuhan keperawatan menggunakan pendekatan teori Virginia henderson pada 1 kasus kelolaan utama dan 30 kasus resume klien HIV/AIDS dengan berbagai infeksi oportunitik. Sebagai peneliti, mahasiswa residensi telah mengaplikasi penerapan intervensi motivasi harian pada klien HIV/AIDS dan hasil dari Evidence Based Nursing ini menunjukkan bahwa intervensi sleep Hygiene dapat meningkatkan kualitas tidur klien HIV. Sedangkan sebagai inovator, telah dilakukan inovasi membuat Booklet Modul HIV Education and Emotional Support (HIVE) Dukungan Sebaya Dalam Meningkatkan Kepatuhan Minum Obat Antiretroviral Therapy dan hasil penerapan proyek inovasi ini menunjukkan manfaat yang sangat signifikan bagi peningkatan kepatuhan minum obat bagi ODHIV.

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Nursing Specialist Practice is an important process of professional education in order to apply the role of specialist nurses that have an impact on efforts to improve the quality of nursing services. This practice is carried out and developed based on science and technology through various studies. Virginia Henderson Model and Bandura's Social Cognitive Theory at Fatmawati Hospital, Jakarta. The three competencies that must be achieved in this residency practice are providing nursing care using a nursing theory approach, implementing nursing implementation based on scientific evidence (evidence based nursing practice), and conducting nursing innovation projects that are useful for the land that is the place of residency practice.

As nursing care providers, residency students have provided nursing care using the Virginia Henderson theory approach to 1 primary management case and 30 resume cases of HIV/AIDS patients with various opportunistic infections. As researchers, residency students have applied the application of daily motivational interventions to HIV/AIDS patients and the results of this Evidence Based Nursing show that sleep hygiene interventions can improve the sleep quality of HIV patients. Meanwhile, as an innovator, an innovation has been made in creating a Booklet Module for HIV Education and Emotional Support (HIVE) Peer Support in Increasing Compliance in Taking Antiretroviral Therapy Medication and the results of implementing this innovation project show very significant benefits for increasing compliance in taking medication for PLHIV.